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Research Output 1987 2019

Article
11 Citations (Scopus)

Development and application of a T-RFLP data analysis method using correlation coefficient matrices

Nakano, Y., Takeshita, T., Kamio, N., Shiota, S., Shibata, Y., Yasui, M. & Yamashita, Y., Dec 1 2008, In : Journal of Microbiological Methods. 75, 3, p. 501-505 5 p.

Research output: Contribution to journalArticle

Restriction Fragment Length Polymorphisms
Environmental Microbiology
Fluorescent Dyes
rRNA Genes
Saliva
5 Citations (Scopus)

Diacylglycerol kinase alpha regulates globular adiponectin-induced reactive oxygen species

Kamio, N., Akifusa, S. & Yamashita, Y., Mar 1 2011, In : Free Radical Research. 45, 3, p. 336-341 6 p.

Research output: Contribution to journalArticle

Diacylglycerol Kinase
Adiponectin
Reactive Oxygen Species
Nitric Oxide
Messenger RNA
38 Citations (Scopus)

Discrimination of Streptococcus pneumoniae from viridans group streptococci by genomic subtractive hybridization

Suzuki, N., Seki, M., Nakano, Y., Kiyoura, Y., Maeno, M. & Yamashita, Y., Sep 1 2005, In : Journal of Clinical Microbiology. 43, 9, p. 4528-4534 7 p.

Research output: Contribution to journalArticle

Viridans Streptococci
Nucleic Acid Hybridization
Streptococcus pneumoniae
Streptococcus mitis
DNA Primers
32 Citations (Scopus)

Discrimination of the oral microbiota associated with high hydrogen sulfide and methyl mercaptan production

Takeshita, T., Suzuki, N., Nakano, Y., Yasui, M., Yoneda, M., Shimazaki, Y., Hirofuji, T. & Yamashita, Y., Apr 19 2012, In : Scientific reports. 2, 215.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Microbiota
Sulfhydryl Compounds
Mouth
Megasphaera
25 Citations (Scopus)

Distinct composition of the oral indigenous microbiota in South Korean and Japanese adults

Takeshita, T., Matsuo, K., Furuta, M., Shibata, Y., Fukami, K., Shimazaki, Y., Akifusa, S., Han, D. H., Kim, H. D., Yokoyama, T., Ninomiya, T., Kiyohara, Y. & Yamashita, Y., Nov 11 2014, In : Scientific reports. 4, 6990.

Research output: Contribution to journalArticle

Microbiota
Veillonella
Prevotella
Haemophilus
Neisseria
3 Citations (Scopus)

Does a clinical evaluation of oral cleanliness correlate with caries incidence in preschool children? Findings from a cohort study.

Seki, M., Karakama, F. & Yamashita, Y., Jun 2003, In : Journal of Oral Science. 45, 2, p. 93-98 6 p.

Research output: Contribution to journalArticle

Streptococcus mutans
Preschool Children
Cohort Studies
Oral Diagnosis
Incidence
5 Citations (Scopus)

Effective method for discriminating between oral bacterial and human alkaline phosphatase activity

Shibata, Y., Yamashita, Y., Miyazaki, H., Ueno, S. & Takehara, T., Jan 1 1994, In : Oral Microbiology and Immunology. 9, 1, p. 35-39 5 p.

Research output: Contribution to journalArticle

Alkaline Phosphatase
Gingival Crevicular Fluid
Bacteria
Sodium Dodecyl Sulfate
Prevotella intermedia
10 Citations (Scopus)

Effectiveness of the salivary occult blood test as a screening method for periodontal status

Shimazaki, Y., Akifusa, S., Takeshita, T., Shibata, Y., Doi, Y., Hata, J., Ninomiya, T., Hirakawa, Y., Kiyohara, Y. & Yamashita, Y., Apr 1 2011, In : Journal of periodontology. 82, 4, p. 581-587 7 p.

Research output: Contribution to journalArticle

Occult Blood
Hematologic Tests
Tooth
Hemorrhage
Periodontal Diseases
10 Citations (Scopus)

Effect of Calcium Ions on Cell Surface Electrostatics of Bacteroides gingivalis and Other Oral Bacteria

Yamashita, Y., Kunimori, A. & Takehara, T., Jan 1 1991, In : Zentralblatt fur Bakteriologie. 275, 1, p. 46-53 8 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Static Electricity
Electrodes
Ions
Calcium

Effect of coffee on the compositional shift of oral indigenous microbiota cultured in vitro

Ogata, K., Takeshita, T., Shibata, Y., Matsumi, R., Kageyama, S., Asakawa, M. & Yamashita, Y., Sep 1 2019, In : Journal of Oral Science. 61, 3, p. 418-424 7 p.

Research output: Contribution to journalArticle

Open Access
Microbiota
Coffee
Streptococcus
Streptococcus mitis
Bacterial Load
1 Citation (Scopus)

Effect of magnesium ions on secretion of glucosyltransferase from Streptococcus sobrinus

Yamashita, Y. & Takehara, T., Dec 1 1989, In : Microbios. 60, 244-245, p. 177-182 6 p.

Research output: Contribution to journalArticle

Streptococcus sobrinus
Glucosyltransferases
Dental Caries
Streptococcus
Magnesium
47 Citations (Scopus)

Effect of mixed mutans streptococci colonization on caries development

Seki, M., Yamashita, Y., Shibata, Y., Torigoe, H., Tsuda, H. & Maeno, M., Feb 1 2006, In : Oral Microbiology and Immunology. 21, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

Streptococcus mutans
Streptococcus sobrinus
Preschool Children
Toothpastes
Polymerase Chain Reaction
17 Citations (Scopus)

Effect of xylitol gum on the level of oral mutans streptococci of preschoolers: Block-randomised trial

Seki, M., Karakama, F., Kawato, T., Tanaka, H., Saeki, Y. & Yamashita, Y., Oct 1 2011, In : International Dental Journal. 61, 5, p. 274-280 7 p.

Research output: Contribution to journalArticle

Xylitol
Streptococcus mutans
Gingiva
Chewing Gum
Diarrhea
4 Citations (Scopus)
Streptococcus sobrinus
Glucosyltransferases
Streptococcus mutans
Surface Antigens
Cell Adhesion
39 Citations (Scopus)
Glucosyltransferases
Streptococcus mutans
Glucans
Surface Antigens
Cell Adhesion
13 Citations (Scopus)

Effects of oil drops containing Lactobacillus salivarius WB21 on periodontal health and oral microbiota producing volatile sulfur compounds

Suzuki, N., Tanabe, K., Takeshita, T., Yoneda, M., Iwamoto, T., Oshiro, S., Yamashita, Y. & Hirofuji, T., Mar 1 2012, In : Journal of Breath Research. 6, 1, 017106.

Research output: Contribution to journalArticle

Sulfur Compounds
Microbiota
Oral Health
Oils
Placebos
6 Citations (Scopus)

Effects of oral care with tongue cleaning on coughing ability in geriatric care facilities: a randomised controlled trial

Izumi, M., Takeuchi, K., Ganaha, S., Akifusa, S. & Yamashita, Y., Dec 1 2016, In : Journal of Oral Rehabilitation. 43, 12, p. 953-959 7 p.

Research output: Contribution to journalArticle

Tongue
Aspiration Pneumonia
Geriatrics
Randomized Controlled Trials
Control Groups
1 Citation (Scopus)

Effects of xylitol-containing chewing gum on the oral microbiota

Takeuchi, K., Asakawa, M., Hashiba, T., Takeshita, T., Saeki, Y. & Yamashita, Y., Dec 1 2018, In : Journal of Oral Science. 60, 4, p. 588-594 7 p.

Research output: Contribution to journalArticle

Chewing Gum
Xylitol
Microbiota
Bacterial Load
Japan
48 Citations (Scopus)
Root Canal Irrigants
Tooth Apex
Dental Pulp Cavity
Equipment and Supplies
Constriction
13 Citations (Scopus)

Enteral tube feeding alters the oral indigenous microbiota in elderly adults

Takeshita, T., Yasui, M., Tomioka, M., Nakano, Y., Shimazaki, Y. & Yamashita, Y., Oct 1 2011, In : Applied and environmental microbiology. 77, 19, p. 6739-6745 7 p.

Research output: Contribution to journalArticle

tube feeding
Microbiota
Enteral Nutrition
mouth
polymorphism
5 Citations (Scopus)

Estimation of tumor necrosis factor-alpha in the diagnosis, the prognosis and the treatment follow-up of oral squamous cell carcinoma.

Kurokawa, H., Yamashita, M., Yamashita, Y., Murata, T., Miura, K. & Kajiyama, M., Jan 1 1998, In : Fukuoka igaku zasshi = Hukuoka acta medica. 89, 11, p. 312-320 9 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Tumor Necrosis Factor-alpha
Serum
Tumor Biomarkers
Therapeutics

Evaluating occlusal caries using a non-destructive Micro-CT examination

Kawato, T., Furuta, M., Ogiso, B., Yamashita, Y., Kitami, S., Iida, T., Kuwabara, A. & Maeno, M., Oct 20 2009, In : Journal of Hard Tissue Biology. 18, 1, p. 35-39 5 p.

Research output: Contribution to journalArticle

Tomography
Tooth
Sensitivity and Specificity
Canes
Three-Dimensional Imaging
34 Citations (Scopus)

Evaluation of mutans streptococci in plaque and saliva: Correlation with caries development in preschool children

Seki, M., Karakama, F., Terajima, T., Ichikawa, Y., Ozaki, T., Yoshida, S. & Yamashita, Y., Jan 1 2003, In : Journal of Dentistry. 31, 4, p. 283-290 8 p.

Research output: Contribution to journalArticle

Streptococcus mutans
Preschool Children
Saliva
Deciduous Tooth
Incidence
1 Citation (Scopus)

Evaluation of neo-adjuvant chemotherapy for oral squamous cell carcinoma

Kurokawa, H., Miura, K., Yamashita, Y., Tokudome, S., Murata, T. & Kajiyama, M., Sep 24 1997, In : Japanese Journal of Cancer and Chemotherapy. 24, 10, p. 1273-1278 6 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Squamous Cell Carcinoma
Carboplatin
Peplomycin
Cisplatin
12 Citations (Scopus)

Evidence for the presence of two distinct sites of sucrose hydrolysis and glucosyl transfer activities on 1,3-α-D-glucan synthase of Streptococcus mutans

Yamashita, Y., Hanada, N., Itoh-Andoh, M. & Takehara, T., Jan 30 1989, In : FEBS Letters. 243, 2, p. 343-346 4 p.

Research output: Contribution to journalArticle

Streptococcus mutans
Sucrose
Hydrolysis
Immune Sera
Enzymes
4 Citations (Scopus)

Exploration of bacterial species associated with the salivary microbiome of individuals with a low susceptibility to dental caries

Yasunaga, H., Takeshita, T., Shibata, Y., Furuta, M., Shimazaki, Y., Akifusa, S., Ninomiya, T., Kiyohara, Y., Takahashi, I. & Yamashita, Y., Nov 1 2017, In : Clinical Oral Investigations. 21, 8, p. 2399-2406 8 p.

Research output: Contribution to journalArticle

Dental Caries Susceptibility
Microbiota
Porphyromonas
Saliva
Tooth
40 Citations (Scopus)

Expression and characterization of streptococcal rgp genes required for rhamnan synthesis in Escherichia coli

Shibata, Y., Yamashita, Y., Ozaki, K., Nakano, Y. & Koga, T., Jun 6 2002, In : Infection and Immunity. 70, 6, p. 2891-2898 8 p.

Research output: Contribution to journalArticle

Rhamnose
Polysaccharides
Escherichia coli
Glucose
Genes
15 Citations (Scopus)

Expression levels of adiponectin receptors and periodontitis

Yamaguchi, N., Hamachi, T., Kamio, N., Akifusa, S., Masuda, K., Nakamura, Y., Nonaka, K., Maeda, K., Hanazawa, S. & Yamashita, Y., Apr 1 2010, In : Journal of Periodontal Research. 45, 2, p. 296-300 5 p.

Research output: Contribution to journalArticle

Adiponectin Receptors
Periodontitis
Periodontal Diseases
Adiponectin
Tumor Necrosis Factor-alpha
2 Citations (Scopus)

Factors affecting the appetites of persons with Alzheimer's disease and mild cognitive impairment

Suma, S., Watanabe, Y., Hirano, H., Kimura, A., Edahiro, A., Awata, S., Yamashita, Y., Matsushita, K., Arai, H. & Sakurai, T., Aug 1 2018, In : Geriatrics and Gerontology International. 18, 8, p. 1236-1243 8 p.

Research output: Contribution to journalArticle

Appetite
dementia
Alzheimer Disease
human being
nutrition
11 Citations (Scopus)

Factors associated with dry mouth in dependent Japanese elderly

Kakudate, N., Muramatsu, T., Endoh, M., Satomura, K., Koseki, T., Sato, Y., Ito, K., Ogasawara, T., Nakamura, S., Kishimoto, E., Kashiwazaki, H., Yamashita, Y., Uchiyama, K., Nishihara, T., Kiyohara, Y. & Kakinoki, Y., Mar 1 2014, In : Gerodontology. 31, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Mouth
Diuretics
Antidepressive Agents
Mouth Breathing
Oral Health
105 Citations (Scopus)

Formation of methyl mercaptan from L-methionine by Porphyromonas gingivalis

Yoshimura, M., Nakano, Y., Yamashita, Y., Oho, T., Saito, T. & Koga, T., Dec 1 2000, In : Infection and Immunity. 68, 12, p. 6912-6916 5 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Sulfhydryl Compounds
Methionine
Virulence
Lyases

Gender-dependent associations between occupational status and untreated caries in japanese adults

Harada, Y., Takeuchi, K., Furuta, M., Tanaka, A., Tanaka, S., Wada, N. & Yamashita, Y., Jan 1 2019, In : Industrial health. 56, 6, p. 539-544 6 p.

Research output: Contribution to journalArticle

Odds Ratio
Confidence Intervals
Tooth
Oral Diagnosis
Forestry
24 Citations (Scopus)

Gender differences in the association between metabolic syndrome and periodontal disease: The Hisayama Study

Furuta, M., Shimazaki, Y., Takeshita, T., Shibata, Y., Akifusa, S., Eshima, N., Kiyohara, Y., Ninomiya, T., Hirakawa, Y., Mukai, N., Nagata, M. & Yamashita, Y., Aug 1 2013, In : Journal of Clinical Periodontology. 40, 8, p. 743-752 10 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Periodontal Diseases
Structural Models
Logistic Models
Regression Analysis
3 Citations (Scopus)

Gender-specific associations of serum antibody to Porphyromonas gingivalis and inflammatory markers

Furuta, M., Shimazaki, Y., Tanaka, S., Takeuchi, K., Shibata, Y., Takeshita, T., Nishimura, F. & Yamashita, Y., Jan 1 2015, In : BioMed Research International. 2015, 897971.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Periodontal Diseases
C-Reactive Protein
Antibodies
Serum
64 Citations (Scopus)

Genes involved in bacitracin resistance in Streptococcus mutans

Tsuda, H., Yamashita, Y., Shibata, Y., Nakano, Y. & Koga, T., Dec 1 2002, In : Antimicrobial Agents and Chemotherapy. 46, 12, p. 3756-3764 9 p.

Research output: Contribution to journalArticle

Bacitracin
Streptococcus mutans
Rhamnose
Genes
Polysaccharides
49 Citations (Scopus)

Genes involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide in Streptococcus mutans

Yamashita, Y., Tsukioka, Y., Tomihisa, K., Nakano, Y. & Koga, T., 1998, In : Journal of Bacteriology. 180, 21, p. 5803-5807 5 p.

Research output: Contribution to journalArticle

Rhamnose
Streptococcus mutans
Cell Wall
Polysaccharides
Glucose
24 Citations (Scopus)

Genetic analysis of the gene cluster for the synthesis of serotype a-specific polysaccharide antigen in Actinobacillus actinomycetemcomitans

Suzuki, N., Nakano, Y., Yoshida, Y., Nakao, H., Yamashita, Y. & Koga, T., Dec 15 2000, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1517, 1, p. 135-138 4 p.

Research output: Contribution to journalArticle

Aggregatibacter actinomycetemcomitans
Multigene Family
Polysaccharides
Genes
Antigens
15 Citations (Scopus)

Genetic analysis of the gene cluster responsible for synthesis of serotype e-specific polysaccharide antigen in Actinobacillus actinomycetemcomitans

Yoshida, Y., Nakano, Y., Suzuki, N., Nakao, H., Yamashita, Y. & Koga, T., Dec 23 1999, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1489, 2-3, p. 457-461 5 p.

Research output: Contribution to journalArticle

Aggregatibacter actinomycetemcomitans
Multigene Family
Polysaccharides
Genes
Antigens

Genetic analysis of the surface protein antigen gene expression in Streptococcus mutans

Koga, T., Yamashita, Y., Tsukioka, Y., Nakano, Y. & Shibata, Y., Oct 23 1997, In : Advances in experimental medicine and biology. 418, p. 673-676 4 p.

Research output: Contribution to journalArticle

Bacterial Gene Expression Regulation
Molecular Sequence Data
Bacterial Outer Membrane Proteins
Bacterial Adhesion
Bacterial Antigens
26 Citations (Scopus)

Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2

Akifusa, S., Kamio, N., Shimazaki, Y., Yamaguchi, N., Nishihara, T. & Yamashita, Y., May 1 2009, In : Free Radical Biology and Medicine. 46, 9, p. 1308-1316 9 p.

Research output: Contribution to journalArticle

Adiponectin
Reactive Oxygen Species
Apoptosis
DNA Damage
DNA
13 Citations (Scopus)

Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans

Suzuki, N., Nakano, Y., Yoshida, Y., Nezu, T., Terada, Y., Yamashita, Y. & Koga, T., Dec 17 2002, In : European Journal of Biochemistry. 269, 23, p. 5963-5971 9 p.

Research output: Contribution to journalArticle

Aggregatibacter actinomycetemcomitans
Guanosine
Diphosphates
Oxidoreductases
Guanosine Diphosphate Mannose
38 Citations (Scopus)

High production of methyl mercaptan by L-methionine-α-deamino- γ-mercaptomethane lyase from Treponema denticola

Fukamachi, H., Nakano, Y., Okano, S., Shibata, Y., Abiko, Y. & Yamashita, Y., May 27 2005, In : Biochemical and Biophysical Research Communications. 331, 1, p. 127-131 5 p.

Research output: Contribution to journalArticle

Treponema denticola
Lyases
Sulfhydryl Compounds
Methionine
Biofilms
18 Citations (Scopus)

Histatin 5 inhibits apoptosis in human gingival fibroblasts induced by Porphyromonas gingivalis cell-surface polyssacharide

Imatani, T., Kato, T., Okuda, K. & Yamashita, Y., Dec 1 2004, In : European Journal of Medical Research. 9, 11, p. 528-532 5 p.

Research output: Contribution to journalArticle

Histatins
Porphyromonas gingivalis
Polysaccharides
Fibroblasts
Apoptosis
26 Citations (Scopus)
Osteogenesis
Transplants
Bone Substitutes
Bone and Bones
Alveolar Process
18 Citations (Scopus)

Histological grading of malignancy correlates with regional lymph node metastasis and survival of patients with oral squamous cell carcinoma.

Kurokawa, H., Yamashita, Y., Murata, T., Yoshikawa, T., Tokudome, S., Miura, K. & Kajiyama, M., Jan 1 1998, In : Fukuoka igaku zasshi = Hukuoka acta medica. 89, 8, p. 225-231 7 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Lymph Nodes
Neoplasm Metastasis
Survival
Neoplasms
43 Citations (Scopus)

Identification and characterization of an autolysin-e cncoding gene of Streptococcus mutans

Shibata, Y., Kawada, M., Nakano, Y., Toyoshima, K. & Yamashita, Y., Jun 1 2005, In : Infection and Immunity. 73, 6, p. 3512-3520 9 p.

Research output: Contribution to journalArticle

N-Acetylmuramoyl-L-alanine Amidase
Streptococcus mutans
Biofilms
Genes
Sucrose
49 Citations (Scopus)

Identification of a fourth gene involved in dTDP-rhamnose synthesis in Streptococcus mutans

Tsukioka, Y., Yamashita, Y., Nakano, Y., Oho, T. & Koga, T., Jan 1 1997, In : Journal of bacteriology. 179, 13, p. 4411-4414 4 p.

Research output: Contribution to journalArticle

Rhamnose
Streptococcus mutans
Genes
Shigella flexneri
Antigens
31 Citations (Scopus)
Frameshift Mutation
Streptococcus mutans
Cell Wall
Antigens
Codon
42 Citations (Scopus)

Identification of a genetic locus essential for serotype b-specific antigen synthesis in Actinobacillus actinomycetemcomitans

Yoshida, Y., Nakano, Y., Yamashita, Y. & Koga, T., 1998, In : Infection and Immunity. 66, 1, p. 107-114 8 p.

Research output: Contribution to journalArticle

Aggregatibacter actinomycetemcomitans
Genetic Loci
Polysaccharides
Antigens
Escherichia coli
6 Citations (Scopus)

Identification of anion channels responsible for fluoride resistance in oral streptococci

Men, X., Shibata, Y., Takeshita, T. & Yamashita, Y., Nov 2016, In : PloS one. 11, 11, e0165900.

Research output: Contribution to journalArticle

Streptococcus
fluorides
Fluorides
Streptococcus sanguinis
anions