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Research Output 1985 2019

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Article
2013
1 Citation (Scopus)

Branched polyethylenimine-based PKCα-responsive gene carriers

Nakamura, Y., Kim, C. W., Tsuchiya, A., Kushio, S., Nobori, T., Li, K., Lee, E. K., Zhao, G. X., Funamoto, D., Niidome, T., Mori, T. & Katayama, Y., Nov 1 2013, In : Journal of Biomaterials Science, Polymer Edition. 24, 16, p. 1858-1868 11 p.

Research output: Contribution to journalArticle

Polyethyleneimine
Protein Kinase C
Peptides
Genes
Proteins

Cancer-specific DDS using stimuli-responsive polymers

Katayama, Y., Aug 2013, In : Kobunshi. 62, 8, p. 452-456 5 p.

Research output: Contribution to journalArticle

Medical nanotechnology
Polymers
Tumors
Pharmaceutical Preparations
Chemotherapy
2 Citations (Scopus)

Cancer-specific gene carriers responding to cancer microenvironment: Acidosis and hyper-activated protein kinases

Kushio, S., Tsuchiya, A., Nakamura, Y., Nobori, T., Kim, C. W., Zhao, G. X., Funamoto, T., Lee, E. K., Niidome, T., Mori, T. & Katayama, Y., Oct 1 2013, In : Biomedical Engineering - Applications, Basis and Communications. 25, 5, 1340005.

Research output: Contribution to journalArticle

Tumor Microenvironment
Neoplasm Genes
Acidosis
Protein Kinases
Polyethylene glycols
33 Citations (Scopus)

CW/pulsed NIR irradiation of gold nanorods: Effect on transdermal protein delivery mediated by photothermal ablation

Tang, H., Kobayashi, H., Niidome, Y., Mori, T., Katayama, Y. & Niidome, T., Jan 1 2013, In : Journal of Controlled Release. 171, 2, p. 178-183 6 p.

Research output: Contribution to journalArticle

Nanotubes
Gold
Skin
Lasers
Proteins
6 Citations (Scopus)

Kinase activity of protein kinase Cα in serum as a diagnostic biomarker of human lung cancer

Kang, J. H., Mori, T., Kitazaki, H., Niidome, T., Takayama, K., Nakanishi, Y. & Katayama, Y., Feb 1 2013, In : Anticancer research. 33, 2, p. 485-488 4 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Biomarkers
Protein Kinase C
Peptides
Serum
4 Citations (Scopus)

PEG-silica-modified gold nanorods that retain their optical properties in tumor tissues

Akiyama, Y., Niidome, Y., Mori, T., Katayama, Y. & Niidome, T., Dec 1 2013, In : Journal of Biomaterials Science, Polymer Edition. 24, 18, p. 2071-2080 10 p.

Research output: Contribution to journalArticle

Nanotubes
Nanorods
Silicon Dioxide
Gold
Polyethylene glycols
14 Citations (Scopus)

Rapid and selective determination of free chlorine in aqueous solution using electrophilic addition to styrene by gas chromatography/mass spectrometry

Wakigawa, K., Gohda, A., Fukushima, S., Mori, T., Niidome, T. & Katayama, Y., Jan 15 2013, In : Talanta. 103, p. 81-85 5 p.

Research output: Contribution to journalArticle

Styrene
Chlorine
Gas chromatography
Gas Chromatography-Mass Spectrometry
Mass spectrometry
4 Citations (Scopus)

Serum protein kinase Cα as a diagnostic biomarker of cancers

Kang, J. H., Mori, T., Kitazaki, H., Niidome, T., Takayama, K., Nakanishi, Y. & Katayama, Y., Jul 29 2013, In : Cancer Biomarkers. 13, 2, p. 99-103 5 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
Protein Kinase C
Blood Proteins
Phosphorylation
Neoplasms
5 Citations (Scopus)

Stabilization of cancer-specific gene carrier via hydrophobic interaction for a clear-cut response to cancer signaling

Kim, C. W., Toita, R., Kang, J. H., Li, K., Lee, E. K., Zhao, G. X., Funamoto, D., Nobori, T., Nakamura, Y., Mori, T., Niidome, T. & Katayama, Y., Jan 1 2013, In : Journal of Controlled Release. 170, 3, p. 469-476 8 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Hydrophobic and Hydrophilic Interactions
Peptides
Polyethyleneimine
Neoplasms
1 Citation (Scopus)

Thermal enhancement of gene transfection in tumor cells mediated by the photothermal effect of gold nanorods

Sakamura, Y., Yoshiura, M., Tang, H., Mori, T., Katayama, Y. & Niidome, T., Jul 15 2013, In : Chemistry Letters. 42, 7, p. 767-768 2 p.

Research output: Contribution to journalArticle

Nanorods
Gold
Tumors
Genes
Cells
2012
18 Citations (Scopus)

A colorimetric assay of protein kinase activity based on peptide-induced coagulation of gold nanorods

Kitazaki, H., Mori, T., Kang, J. H., Niidome, T., Murata, M., Hashizume, M. & Katayama, Y., Nov 1 2012, In : Colloids and Surfaces B: Biointerfaces. 99, p. 7-11 5 p.

Research output: Contribution to journalArticle

Nanotubes
coagulation
Coagulation
Nanorods
Gold
8 Citations (Scopus)

A novel double-coating carrier produced by solid-in-oil and solid-in-water nanodispersion technology for delivery of genes and proteins into cells

Tahara, Y., Kaneko, T., Toita, R., Yoshiyama, C., Kitaoka, T., Niidome, T., Katayama, Y., Kamiya, N. & Goto, M., Aug 10 2012, In : Journal of Controlled Release. 161, 3, p. 713-721 9 p.

Research output: Contribution to journalArticle

Oils
Technology
Water
Proteins
Ovalbumin
5 Citations (Scopus)

Biodistribution and tumor localization of peg-modified dendritic poly(L-lysine) oligonucleotide complexes

Kurihara, R., Pissuwan, D., Mori, T., Katayama, Y. & Niidome, T., Oct 12 2012, In : Journal of Biomaterials Science, Polymer Edition. 23, 18, p. 2369-2380 12 p.

Research output: Contribution to journalArticle

Oligonucleotides
Polyethylene glycols
Lysine
Tumors
Neoplasms
24 Citations (Scopus)

Conversion of rod-shaped gold nanoparticles to spherical forms and their effect on biodistribution in tumor-bearing mice

Akiyama, Y., Mori, T., Katayama, Y. & Niidome, T., Jan 1 2012, In : Nanoscale Research Letters. 7, p. 1-6 6 p., 565.

Research output: Contribution to journalArticle

Bearings (structural)
Gold
mice
Tumors
Nanorods
2 Citations (Scopus)
Phosphorylation
Radioactivity
Ionization
Mass spectrometry
Assays
2 Citations (Scopus)

Creating a unique environment for selecting reactive enzymes with DNA: 'Sticky' binding of oligocation-grafted polymers to DNA

Tanaka, H., Mori, T., Niidome, T. & Katayama, Y., Feb 1 2012, In : Bioorganic and Medicinal Chemistry. 20, 3, p. 1346-1353 8 p.

Research output: Contribution to journalArticle

Polymers
Graft copolymers
DNA
Enzymes
Transplants
6 Citations (Scopus)

Fluorometric detection of protein kinase Cα activity based on phosphorylation-induced dissociation of a polyion complex

Toita, R., Mori, T., Naritomi, Y., Kang, J. H., Shiosaki, S., Niidome, T. & Katayama, Y., May 15 2012, In : Analytical Biochemistry. 424, 2, p. 130-136 7 p.

Research output: Contribution to journalArticle

Phosphorylation
Protein Kinase C
Fluorescence
Polymers
Infrared radiation
66 Citations (Scopus)

Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier

Arima, H., Yoshimatsu, A., Ikeda, H., Ohyama, A., Motoyama, K., Higashi, T., Tsuchiya, A., Niidome, T., Katayama, Y., Hattori, K. & Takeuchi, T., Sep 4 2012, In : Molecular pharmaceutics. 9, 9, p. 2591-2604 14 p.

Research output: Contribution to journalArticle

Dendrimers
Cyclodextrins
Folic Acid
Small Interfering RNA
Neoplasms
22 Citations (Scopus)

Gene carrier showing all-or-none response to cancer cell signaling

Toita, R., Kang, J. H., Tomiyama, T., Kim, C. W., Shiosaki, S., Niidome, T., Mori, T. & Katayama, Y., Sep 19 2012, In : Journal of the American Chemical Society. 134, 37, p. 15410-15417 8 p.

Research output: Contribution to journalArticle

Cell signaling
Protein Kinase C
Genes
Peptides
Proteins
25 Citations (Scopus)

Gold nanorods in an oil-base formulation for transdermal treatment of type 1 diabetes in mice

Nose, K., Pissuwan, D., Goto, M., Katayama, Y. & Niidome, T., Jun 12 2012, In : Nanoscale. 4, 12, p. 3776-3780 5 p.

Research output: Contribution to journalArticle

Insulin
Medical problems
Nanorods
Gold
Oils
5 Citations (Scopus)

Improvement in the colloidal stability of protein kinase-responsive polyplexes by PEG modification

Tsuchiya, A., Naritomi, Y., Kushio, S., Kang, J. H., Murata, M., Hashizume, M., Mori, T., Niidome, T. & Katayama, Y., May 1 2012, In : Journal of Biomedical Materials Research - Part A. 100 A, 5, p. 1136-1141 6 p.

Research output: Contribution to journalArticle

Protein Kinases
Polyethylene glycols
Proteins
Cyclic AMP-Dependent Protein Kinases
Polymers

Kinome analysis using microarray of peptide substrates

Mori, T., Kamimoto, J. & Katayama, Y., Jan 1 2012, In : bunseki kagaku. 61, 3, p. 185-191 7 p.

Research output: Contribution to journalArticle

Microarrays
Protein Kinases
Peptides
Substrates
Signal transduction
7 Citations (Scopus)

Sequential release of single-stranded dnas from gold nanorods triggered by near-infrared light irradiation

Fukushima, H., Yamashita, S., Mori, T., Katayama, Y. & Niidome, T., Jul 30 2012, In : Chemistry Letters. 41, 7, p. 711-712 2 p.

Research output: Contribution to journalArticle

Nanorods
Gold
Melting point
Irradiation
Infrared radiation
2011
2 Citations (Scopus)

A hydrophilic polymer grafted with a histone tail peptide as an artificial gene regulator

Shiosaki, S., Kuramoto, M., Toita, R., Mori, T., Niidome, T. & Katayama, Y., Jul 1 2011, In : Bioorganic and Medicinal Chemistry. 19, 13, p. 4101-4105 5 p.

Research output: Contribution to journalArticle

Synthetic Genes
Gene expression
Histones
Chromatin
Polymers
3 Citations (Scopus)

A simple set-and-mix assay for screening of protein kinase inhibitors in cell lysates

Asami, Y., Oishi, J., Kitazaki, H., Kamimoto, J., Kang, J. H., Niidome, T., Mori, T. & Katayama, Y., Nov 1 2011, In : Analytical Biochemistry. 418, 1, p. 44-49 6 p.

Research output: Contribution to journalArticle

Coagulants
Preclinical Drug Evaluations
Protein Kinase Inhibitors
Cyclic AMP-Dependent Protein Kinases
Gold
36 Citations (Scopus)

A solid-in-oil dispersion of gold nanorods can enhance transdermal protein delivery and skin vaccination

Pissuwan, D., Nose, K., Kurihara, R., Kaneko, K., Tahara, Y., Kamiya, N., Goto, M., Katayama, Y. & Niidome, T., Jan 17 2011, In : Small. 7, 2, p. 215-220 6 p.

Research output: Contribution to journalArticle

Nanotubes
Molecular Models
Ovalbumin
Nanorods
Gold
41 Citations (Scopus)

Controlled-release system mediated by a retro Diels-Alder reaction induced by the photothermal effect of gold nanorods

Yamashita, S., Fukushima, H., Niidome, Y., Mori, T., Katayama, Y. & Niidome, T., Dec 6 2011, In : Langmuir. 27, 23, p. 14621-14626 6 p.

Research output: Contribution to journalArticle

Diels-Alder reactions
Nanorods
Gold
nanorods
gold
54 Citations (Scopus)

Controlled-release system of single-stranded DNA triggered by the photothermal effect of gold nanorods and its in vivo application

Yamashita, S., Fukushima, H., Akiyama, Y., Niidome, Y., Mori, T., Katayama, Y. & Niidome, T., Apr 1 2011, In : Bioorganic and Medicinal Chemistry. 19, 7, p. 2130-2135 6 p.

Research output: Contribution to journalArticle

Nanotubes
Nanorods
Gold
Light
Irradiation
6 Citations (Scopus)

Effect of introduction of chondroitin sulfate into polymer-peptide conjugate responding to intracellular signals

Tomiyama, T., Toita, R., Kang, J. H., Koga, H., Shiosaki, S., Mori, T., Niidome, T. & Katayama, Y., Dec 1 2011, In : Nanoscale Research Letters. 6, p. 1-7 7 p., 532.

Research output: Contribution to journalArticle

Chondroitin Sulfates
Peptides
peptides
sulfates
Polymers
15 Citations (Scopus)

Fluorescent nanoparticles consisting of lipopeptides and fluorescein-modified polyanions for monitoring of protein kinase activity

Koga, H., Toita, R., Mori, T., Tomiyama, T., Kang, J. H., Niidome, T. & Katayama, Y., Aug 17 2011, In : Bioconjugate Chemistry. 22, 8, p. 1526-1534 9 p.

Research output: Contribution to journalArticle

Lipopeptides
Fluorescein
Nanoparticles
Protein Kinases
Proteins
7 Citations (Scopus)

Optimization of peptide density on microarray surface for quantitative phosphoproteomics

Shimomura, T., Han, X., Hata, A., Niidome, T., Mori, T. & Katayama, Y., 2011, In : analytical sciences. 27, 1, p. 13-17 5 p.

Research output: Contribution to journalArticle

Microarrays
Peptides
Phosphotyrosine
Antibodies
Coordination Complexes
15 Citations (Scopus)

Peptide substrates for Rho-Associated kinase 2 (Rho-Kinase 2/ROCK2)

Kang, J. H., Asai, D., Tsuchiya, A., Mori, T., Niidome, T. & Katayama, Y., Aug 1 2011, In : PloS one. 6, 7, e22699.

Research output: Contribution to journalArticle

rho-Associated Kinases
phosphotransferases (kinases)
peptides
Peptides
Substrates
6 Citations (Scopus)

Transgene regulation system responding to Rho associated coiled-coil kinase (ROCK) activation

Tsuchiya, A., Kang, J. H., Asai, D., Mori, T., Niidome, T. & Katayama, Y., Oct 10 2011, In : Journal of Controlled Release. 155, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

rho-Associated Kinases
Transgenes
Polymers
Gene Expression
Gene Transfer Techniques
2010
35 Citations (Scopus)

Active accumulation of gold nanorods in tumor in response to near-infrared laser irradiation

Shiotani, A., Akiyama, Y., Kawano, T., Niidome, Y., Mori, T., Katayama, Y. & Niidome, T., Nov 17 2010, In : Bioconjugate Chemistry. 21, 11, p. 2049-2054 6 p.

Research output: Contribution to journalArticle

Nanotubes
Infrared lasers
Laser beam effects
Nanorods
Gold
6 Citations (Scopus)

A gene-delivery system specific for hepatoma cells and an intracellular kinase signal based on human liver-specific bionanocapsules and signal-responsive artificial polymer

Oishi, J., Jung, J., Tsuchiya, A., Toita, R., Kang, J. H., Mori, T., Niidome, T., Tanizawa, K., Kuroda, S. & Katayama, Y., Aug 1 2010, In : International Journal of Pharmaceutics. 396, 1-2, p. 174-178 5 p.

Research output: Contribution to journalArticle

Gene Transfer Techniques
Hepatocellular Carcinoma
Polymers
Phosphotransferases
Liver
11 Citations (Scopus)

A peptide microarray for detecting protein kinase activity in cell lysates.

Han, X. & Katayama, Y., 2010, In : Methods in molecular biology (Clifton, N.J.). 669, p. 183-194 12 p.

Research output: Contribution to journalArticle

Protein Kinases
Peptides
Fluorescence
Drug Discovery
Phosphotransferases
3 Citations (Scopus)

Characterization of gene expression regulation using D-RECS polymer by enzymatic reaction for an effective design of enzyme-responsive gene regulator

Sato, Y. T., Kawamura, K., Niidome, T. & Katayama, Y., May 1 2010, In : Journal of Controlled Release. 143, 3, p. 344-349 6 p.

Research output: Contribution to journalArticle

Gene Expression Regulation
Regulator Genes
Polymers
Enzymes
Gene Transfer Techniques
35 Citations (Scopus)

Controlled release of PEG chain from gold nanorods: Targeted delivery to tumor

Niidome, T., Ohga, A., Akiyama, Y., Watanabe, K., Niidome, Y., Mori, T. & Katayama, Y., Jun 15 2010, In : Bioorganic and Medicinal Chemistry. 18, 12, p. 4453-4458 6 p.

Research output: Contribution to journalArticle

Nanotubes
Nanorods
Gold
Polyethylene glycols
Tumors
16 Citations (Scopus)

Design of temperature-responsive polymers with enhanced hysteresis: α,α-disubstituted vinyl polymers

Mori, T., Beppu, S., Berber, M. R., Mori, H., Makimura, T., Tsukamoto, A., Minagawa, K., Hirano, T., Tanaka, M., Niidome, T., Katayama, Y., Hirano, T. & Maeda, Y., Jun 15 2010, In : Langmuir. 26, 12, p. 9224-9232 9 p.

Research output: Contribution to journalArticle

vinyl polymers
Hysteresis
Polymers
hysteresis
polymers
44 Citations (Scopus)

Gold nanoparticle-based colorimetric assay for cancer diagnosis

Kang, J. H., Asami, Y., Murata, M., Kitazaki, H., Sadanaga, N., Tokunaga, E., Shiotani, S., Okada, S., Maehara, Y., Niidome, T., Hashizume, M., Mori, T. & Katayama, Y., Apr 15 2010, In : Biosensors and Bioelectronics. 25, 8, p. 1869-1874 6 p.

Research output: Contribution to journalArticle

Gold
Nanoparticles
Assays
Protein Kinase C
Tissue
14 Citations (Scopus)

Hepatoma-targeted gene delivery using a tumor cell-specific gene regulation system combined with a human liver cell-specific bionanocapsule

Kang, J. H., Oishi, J., Kim, J. H., Ijuin, M., Toita, R., Jun, B., Asai, D., Mori, T., Niidome, T., Tanizawa, K., Kuroda, S. & Katayama, Y., Aug 2010, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 6, 4, p. 583-589 7 p.

Research output: Contribution to journalArticle

Gene expression
Liver
Tumors
Hepatocellular Carcinoma
Genes
27 Citations (Scopus)

Polydispersity as a parameter for indicating the thermal stability of proteins by dynamic light scattering

Shiba, K., Niidome, T., Katoh, E., Xiang, H., Han, L., Mori, T. & Katayama, Y., Jun 2010, In : analytical sciences. 26, 6, p. 659-663 5 p.

Research output: Contribution to journalArticle

Polydispersity
Dynamic light scattering
Thermodynamic stability
Melting point
Differential scanning calorimetry
6 Citations (Scopus)

Progress in current non-viral carriers for gene delivery

Shoji-Moskowitz, Y., Asai, D., Kodama, K., Katayama, Y. & Nakashima, H., Jan 1 2010, In : Frontiers in Medicinal Chemistry. 5, 1, p. 81-97 17 p.

Research output: Contribution to journalArticle

Gene therapy
Genetic Therapy
Genes
HIV Protease
Viral Genes
15 Citations (Scopus)

Protein kinase substrate profiling with a high-density peptide microarray

Han, X., Sonoda, T., Mori, T., Yamanouchi, G., Yamaji, T., Shigaki, S., Niidome, T. & Katayama, Y., Nov 1 2010, In : Combinatorial Chemistry and High Throughput Screening. 13, 9, p. 777-789 13 p.

Research output: Contribution to journalArticle

Microarrays
Protein Kinases
Peptides
Proteins
Substrates
14 Citations (Scopus)

Specific transgene expression in HIV-infected cells using protease-cleavable transcription regulator

Asai, D., Kuramoto, M., Shoji, Y., Kang, J. H., Kodama, K. B., Kawamura, K., Mori, T., Miyoshi, H., Niidome, T., Nakashima, H. & Katayama, Y., Jan 4 2010, In : Journal of Controlled Release. 141, 1, p. 52-61 10 p.

Research output: Contribution to journalArticle

Transgenes
Peptide Hydrolases
HIV
Peptides
Picornaviridae
5 Citations (Scopus)

Targeted delivery of gold nanorods modified with thermo-sensitive polymer.

Niidome, T., Shiotani, A., Mori, T. & Katayama, Y., Nov 20 2010, In : Journal of Controlled Release. 148, 1

Research output: Contribution to journalArticle

Acrylic Resins
Nanotubes
Drug Delivery Systems
Gold
Polymers
10 Citations (Scopus)

Tumor therapy by gene regulation system responding to cellular signal

Tomiyama, T., Toita, R., Kang, J. H., Asai, D., Shiosaki, S., Mori, T., Niidome, T. & Katayama, Y., Nov 20 2010, In : Journal of Controlled Release. 148, 1, p. 101-105 5 p.

Research output: Contribution to journalArticle

Genetic Therapy
Protein Kinase C
Neoplasms
Gene Transfer Techniques
Polymers
16 Citations (Scopus)

Unusually Large Hysteresis of Temperature-Responsive Poly(N-ethyl-2- propionamidoacrylamide) Studied by Microcalorimetry and FT-IR

Berber, M. R., Mori, H., Hafez, I. H., Minagawa, K., Tanaka, M., Niidome, T., Katayama, Y., Maruyama, A., Hirano, T., Maeda, Y. & Mori, T., Jun 17 2010, In : Journal of Physical Chemistry B. 114, 23, p. 7784-7790 7 p.

Research output: Contribution to journalArticle

Phase Transition
Hysteresis
Transition Temperature
hysteresis
Temperature
2009
8 Citations (Scopus)

A novel protease activity assay using a protease-responsive chaperone protein

Sao, K., Murata, M., Fujisaki, Y., Umezaki, K., Mori, T., Niidome, T., Katayama, Y. & Hashizume, M., Jun 5 2009, In : Biochemical and Biophysical Research Communications. 383, 3, p. 293-297 5 p.

Research output: Contribution to journalArticle

Assays
Peptide Hydrolases
Proteins
Factor Xa
Small Heat-Shock Proteins
7 Citations (Scopus)

A syngeneic hepatocellular carcinoma model rapidly and simply prepared using a hydrodynamics-based procedure

Kang, J. H., Mori, T., Niidome, T. & Katayama, Y., Sep 1 2009, In : Veterinary Journal. 181, 3, p. 336-339 4 p.

Research output: Contribution to journalArticle

hepatoma
Hydrodynamics
hydrodynamics
Hepatocellular Carcinoma
liver neoplasms