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Research Output 1980 2019

2019
2 Citations (Scopus)

Budding Uninhibited by Benzimidazole-1 Insufficiency Prevents Acute Renal Failure in Severe Sepsis by Maintaining Anticoagulant Functions of Vascular Endothelial Cells

Matsubara, Y., Matsumoto, T., Yoshiya, K., Yoshida, A., Ikeda, S., Furuyama, T., Nakatsu, Y., Tsuzuki, T., Nomura, M. & Maehara, Y., Mar 1 2019, In : Shock. 51, 3, p. 364-371 8 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Anticoagulants
Sepsis
Endothelial Cells
Thrombomodulin

Corrigendum to “Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing” [Exp. Cell Res. 377 (2019) 24–35](S0014482719300825)(10.1016/j.yexcr.2019.02.020)

Hayashida, G., Shioi, S., Hidaka, K., Fujikane, R., Hidaka, M., Tsurimoto, T., Tsuzuki, T., Oda, S. & Nakatsu, Y., Oct 1 2019, In : Experimental Cell Research. 383, 1, 111432.

Research output: Contribution to journalComment/debate

Flap Endonucleases
Escherichia coli
Methylnitrosourea
Mutation
Genomic Instability

Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing

Hayashida, G., Shioi, S., Hidaka, K., Fujikane, R., Hidaka, M., Tsurimoto, T., Tsuzuki, T., Oda, S. & Nakatsu, Y., Apr 15 2019, In : Experimental Cell Research. 377, 1-2, p. 24-35 12 p.

Research output: Contribution to journalArticle

Open Access
Microsatellite Instability
DNA Mismatch Repair
Mutation
Microsatellite Repeats
Hereditary Nonpolyposis Colorectal Neoplasms

Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro

Matsuno, Y., Atsumi, Y., Shimizu, A., Katayama, K., Fujimori, H., Hyodo, M., Minakawa, Y., Nakatsu, Y., Kaneko, S., Hamamoto, R., Shimamura, T., Miyano, S., Tsuzuki, T., Hanaoka, F. & Yoshioka, K. I., Dec 1 2019, In : Nature communications. 10, 1, 3925.

Research output: Contribution to journalArticle

Open Access
microsatellites
Microsatellite Instability
DNA Mismatch Repair
destabilization
Microsatellite Repeats
2018

Effects of mismatches distant from the target position on gene correction with a 5′-tailed duplex

Suzuki, T., Yanai, Y., Nishigaki, N., Nakatsu, Y., Tsuzuki, T. & Kamiya, H., May 1 2018, In : Journal of Bioscience and Bioengineering. 125, 5, p. 619-623 5 p.

Research output: Contribution to journalArticle

Gene Order
Genes
DNA
Substitution reactions
Mutation
2017
11 Citations (Scopus)

Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway

Egashira, I., Takahashi-Yanaga, F., Nishida, R., arioka, M., Igawa, K., Tomooka, K., Nakatsu, Y., Tsuzuki, T., Nakabeppu, Y., Kitazono, T. & Sasaguri, T., Jan 1 2017, In : Cancer Science. 108, 1, p. 108-115 8 p.

Research output: Contribution to journalArticle

Celecoxib
Intestinal Neoplasms
Catenins
Wnt Signaling Pathway
Growth

Gene transfer by circulating plasma bubble flow

Yamanishi, Y., Tanaka, R., Arakawa, Y. & Nakatsu, Y., Feb 23 2017, 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017. Institute of Electrical and Electronics Engineers Inc., p. 444-447 4 p. 7863438. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

plasma bubbles
Gene transfer
genes
liquid air
Plasmas
2016
6 Citations (Scopus)

BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector

Yamamoto, H., ishimura, M., Ochiai, M., Takada, H., Kusuhara, K., Nakatsu, Y., Tsuzuki, T., Mitani, K. & Hara, T., Feb 1 2016, In : Gene Therapy. 23, 2, p. 205-213 9 p.

Research output: Contribution to journalArticle

Dependovirus
Gene Targeting
Homologous Recombination
Adenoviridae
Genetic Therapy
2 Citations (Scopus)

BubR1 Insufficiency Impairs Liver Regeneration in Aged Mice after Hepatectomy through Intercalated Disc Abnormality

Ikawa-Yoshida, A., matsumoto, T., Okano, S., Aoyagi, Y., Matsubara, Y., Furuyama, T., Nakatsu, Y., Tsuzuki, T., Onimaru, M., Ohkusa, T., Nomura, M. & Maehara, Y., Aug 26 2016, In : Scientific reports. 6, 32399.

Research output: Contribution to journalArticle

Liver Regeneration
Hepatectomy
Desmocollins
Hepatocytes
Liver
2 Citations (Scopus)

BUBR1 insufficiency in mice increases their sensitivity to oxidative stress

Matsuda, D., matsumoto, T., Honma, K., Ikawa-Yoshida, A., Onimaru, M., Furuyama, T., Nakatsu, Y., Tsuzuki, T. & Maehara, Y., Nov 1 2016, In : In Vivo. 30, 6, p. 769-776 8 p.

Research output: Contribution to journalArticle

Oxidative stress
Oxidative Stress
Water
Chromosomes
Tumors
3 Citations (Scopus)

Insertion and deletion mismatches distant from the target position improve gene correction with a tailed duplex

Kamiya, H., Nishigaki, N., Ikeda, A., Yukawa, S., Morita, Y., Nakatsu, Y., Tsuzuki, T. & Harashima, H., Jul 2 2016, In : Nucleosides, Nucleotides and Nucleic Acids. 35, 7, p. 379-388 10 p.

Research output: Contribution to journalArticle

Gene Order
Genes
DNA
HeLa Cells
Plasmids
2015
8 Citations (Scopus)

BubR1 insufficiency inhibits neointimal hyperplasia through impaired vascular smooth muscle cell proliferation in mice

Kyuragi, R., matsumoto, T., Harada, Y., Saito, S., Onimaru, M., Nakatsu, Y., Tsuzuki, T., Nomura, M., Yonemitsu, Y. & Maehara, Y., Feb 2 2015, In : Arteriosclerosis, thrombosis, and vascular biology. 35, 2, p. 341-347 7 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Hyperplasia
Cell Proliferation
Bone Marrow Transplantation
8 Citations (Scopus)

Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo

Kubokura, N., Takahashi, F., arioka, M., Yoshihara, T., Igawa, K., Tomooka, K., Morimoto, S., Nakatsu, Y., Tsuzuki, T., Nakabeppu, Y., Matsumoto, T., Kitazono, T. & Sasaguri, T., Jan 1 2015, In : Journal of Pharmacological Sciences. 127, 4, p. 446-455 10 p.

Research output: Contribution to journalArticle

Growth
Neoplasms
Intestinal Neoplasms
Catenins
Dictyostelium
7 Citations (Scopus)

UV-induced mutations in epidermal cells of mice defective in DNA polymerase η and/or ι

Kanao, R., Yokoi, M., Ohkumo, T., Sakurai, Y., Dotsu, K., Kura, S., Nakatsu, Y., Tsuzuki, T., Masutani, C. & Hanaoka, F., May 1 2015, In : DNA Repair. 29, p. 139-146 8 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Cells
Mutation
Cytosine
Dimers
2014
13 Citations (Scopus)

Abnormality in Wnt signaling is causatively associated with oxidative stress-induced intestinal tumorigenesis in MUTYH-null mice

Isoda, T., Nakatsu, Y., Yamauchi, K., Piao, J., Yao, T., Honda, H., Nakabeppu, Y. & Tsuzuki, T., Aug 23 2014, In : International journal of biological sciences. 10, 8, p. 940-947 8 p.

Research output: Contribution to journalArticle

abnormality
tumor
carcinogenesis
Carcinogenesis
Oxidative Stress
14 Citations (Scopus)

DIF-1 inhibits tumor growth in vivo reducing phosphorylation of GSK-3β and expressions of cyclin D1 and TCF7L2 in cancer model mice

Takahashi, F., Yoshihara, T., Jingushi, K., Igawa, K., Tomooka, K., Watanabe, Y., Morimoto, S., Nakatsu, Y., Tsuzuki, T., Nakabeppu, Y. & Sasaguri, T., Jun 1 2014, In : Biochemical Pharmacology. 89, 3, p. 340-348 9 p.

Research output: Contribution to journalArticle

T Cell Transcription Factor 1
Glycogen Synthase Kinase 3
Phosphorylation
Cyclin D1
Tumors
2013
11 Citations (Scopus)

Mismatch repair deficient mice show susceptibility to oxidative stress-induced intestinal carcinogenesis.

Piao, J., Nakatsu, Y., Mizuki, O., Taguchi, K. I. & Tsuzuki, T., Jan 1 2013, In : International journal of biological sciences. 10, 1, p. 73-79 7 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
tumor
carcinogenesis
repair
Carcinogenesis
2012
13 Citations (Scopus)

Activation of AMP-activated protein kinase by MAPO1 and FLCN induces apoptosis triggered by alkylated base mismatch in DNA

Lim, T. H., Fujikane, R., Sano, S., Sakagami, R., Nakatsu, Y., Tsuzuki, T., Sekiguchi, M. & Hidaka, M., Mar 1 2012, In : DNA Repair. 11, 3, p. 259-266 8 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Estrone
Chemical activation
Apoptosis
DNA
2011

[Oxidative DNA damage-induced intestinal tumorigenesis in Mutyh-deficient mice].

Tsuzuki, T., Piao, J. S. & Nakatsu, Y., Apr 1 2011, In : Nihon rinsho. Japanese journal of clinical medicine. 69 Suppl 3, p. 137-142 6 p.

Research output: Contribution to journalArticle

DNA Glycosylases
Intestinal Neoplasms
DNA Damage
Carcinogenesis
Oxidative Stress
15 Citations (Scopus)

Cleavage of oxidized guanine nucleotide and ADP sugar by human NUDT5 protein

Ito, R., Sekiguchi, M., Setoyama, D., Nakatsu, Y., Yamagata, Y. & Hayakawa, H., Jun 1 2011, In : Journal of Biochemistry. 149, 6, p. 731-738 8 p.

Research output: Contribution to journalArticle

Adenosine Diphosphate Sugars
Adenosine Diphosphate Ribose
Guanine Nucleotides
Adenosine Monophosphate
Sugar Phosphates
1 Citation (Scopus)

Oxidative stress-induced tumorigenesis in the small intestines of DNA repair-deficient mice.

Tsuzuki, T., Piao, J. S., Isoda, T., Kunihiko, S., Nakabeppu, Y. & Nakatsu, Y., Mar 1 2011, In : Health Physics. 100, 3, p. 293-294 2 p.

Research output: Contribution to journalConference article

DNA Mutational Analysis
Bromates
Neoplastic Cell Transformation
Radiation-Induced Neoplasms
DNA Repair-Deficiency Disorders
2010
4 Citations (Scopus)

Targeted sequence alteration of a chromosomal locus in mouse liver

Kamiya, H., Uchiyama, M., Piao, J., Nakatsu, Y., Tsuzuki, T. & Harashima, H., Mar 1 2010, In : International Journal of Pharmaceutics. 387, 1-2, p. 180-183 4 p.

Research output: Contribution to journalArticle

Biotechnology
Transgenes
Genetic Therapy
Single-Stranded DNA
Liver
2009
10 Citations (Scopus)

A novel protein, MAPO1, that functions in apoptosis triggered by O 6-methylguanine mispair in DNA

Komori, K., Takagi, Y., Sanada, M., Lim, T. H., Nakatsu, Y., Tsuzuki, T., Sekiguchi, M. & Hidaka, M., Feb 26 2009, In : Oncogene. 28, 8, p. 1142-1150 9 p.

Research output: Contribution to journalArticle

Apoptosis
DNA
Proteins
Genes
Methyl Methanesulfonate
2008
8 Citations (Scopus)

Effects of target sequence and sense versus anti-sense strands on gene correction with single-stranded DNA fragments

Kamiya, H., Uchiyama, M., Nakatsu, Y., Tsuzuki, T. & Harashima, H., Oct 1 2008, In : Journal of biochemistry. 144, 4, p. 431-436 6 p.

Research output: Contribution to journalArticle

Single-Stranded DNA
Genes
Proprioception
Gene Fusion
Plasmids
15 Citations (Scopus)

Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice

Nakane, H., Hirota, S., Brooks, P. J., Nakabeppu, Y., Nakatsu, Y., Nishimune, Y., Iino, A. & Tanaka, K., Dec 1 2008, In : DNA Repair. 7, 12, p. 1938-1950 13 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum
Spermatogenesis
Tumors
Skin
Carcinogenesis
11 Citations (Scopus)

Improved gene correction efficiency with a tailed duplex DNA fragment

Tsuchiya, H., Uchiyama, M., Hara, K., Nakatsu, Y., Tsuzuki, T., Inoue, H., Harashima, H. & Kamiya, H., Aug 19 2008, In : Biochemistry. 47, 33, p. 8754-8759 6 p.

Research output: Contribution to journalArticle

Genes
Single-Stranded DNA
DNA
Oligonucleotides
Rad51 Recombinase
59 Citations (Scopus)

Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair

Kuraoka, I., Ito, S., Wada, T., Hayashida, M., Lee, L., Saijo, M., Nakatsu, Y., Matsumoto, M., Matsunaga, T., Handa, H., Qin, J., Nakatani, Y. & Tanaka, K., Jan 11 2008, In : Journal of Biological Chemistry. 283, 2, p. 940-950 11 p.

Research output: Contribution to journalArticle

RNA Precursors
Transcription
Carrier Proteins
Repair
Cockayne Syndrome
2007
20 Citations (Scopus)

Modes of actions of two types of anti-neoplastic drugs, dacarbazine and ACNU, to induce apoptosis

Sanada, M., Hidaka, M., Takagi, Y., Takano, T. Y., Nakatsu, Y., Tsuzuki, T. & Sekiguchi, M., Dec 1 2007, In : Carcinogenesis. 28, 12, p. 2657-2663 7 p.

Research output: Contribution to journalArticle

Nimustine
Dacarbazine
Methyltransferases
Apoptosis
DNA
92 Citations (Scopus)

MUTYH-null mice are susceptible to spontaneous and oxidative stress-induced intestinal tumorigenesis

Sakamoto, K., Tominaga, Y., Yamauchi, K., Nakatsu, Y., Kunihiko, S., Yoshiyama, K., Egashira, A., Kura, S., Yao, T., Tsuneyoshi, M., Maki, H., Nakabeppu, Y. & Tsuzuki, T., Jul 15 2007, In : Cancer Research. 67, 14, p. 6599-6604 6 p.

Research output: Contribution to journalArticle

Carcinogenesis
Oxidative Stress
Adenoma
Small Intestine
Neoplasms
73 Citations (Scopus)

Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis

Tsuzuki, T., Nakatsu, Y. & Nakabeppu, Y., Apr 1 2007, In : Cancer Science. 98, 4, p. 465-470 6 p.

Research output: Contribution to journalReview article

Mutagenesis
DNA Damage
Carcinogenesis
Adenine
Escherichia coli
2006
178 Citations (Scopus)

Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids.

Nakabeppu, Y., Kunihiko, S., Sakamoto, K., Tsuchimoto, D., Tsuzuki, T. & Nakatsu, Y., Jan 1 2006, In : Biological chemistry. 387, 4, p. 373-379 7 p.

Research output: Contribution to journalConference article

DNA Glycosylases
Mutagenesis
Nucleic Acids
Carcinogenesis
Genes
5 Citations (Scopus)

Oxidative damage to nucleotide: Consequences and preventive mechanisms

Nakatsu, Y. & Sekiguchi, M., Jan 1 2006, Oxidative Stress, Disease and Cancer. Imperial College Press, p. 221-252 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nucleotides
2005
25 Citations (Scopus)

Disruption of mouse XAB2 gene involved in pre-mRNA splicing, transcription and transcription-coupled DNA repair results in preimplantation lethality

Yonemasu, R., Minami, M., Nakatsu, Y., Takeuchi, M., Kuraoka, I., Matsuda, Y., Higashi, Y., Kondoh, H. & Tanaka, K., Apr 4 2005, In : DNA Repair. 4, 4, p. 479-491 13 p.

Research output: Contribution to journalArticle

RNA Precursors
Transcription
DNA Repair
Xeroderma Pigmentosum Group A Protein
Repair
2003
31 Citations (Scopus)

Three novel mutations responsible for Cockayne syndrome group A

Ren, Y., Saijo, M., Nakatsu, Y., Nakai, H., Yamaizumi, M. & Tanaka, K., Feb 1 2003, In : Genes and Genetic Systems. 78, 1, p. 93-102 10 p.

Research output: Contribution to journalArticle

Cockayne Syndrome
Mutation
Exons
Founder Effect
Polymerase Chain Reaction
2002
24 Citations (Scopus)

Additive roles of XPA and MSH2 genes in UVB-induced skin tumorigenesis in mice

Yoshino, M., Nakatsu, Y., Riele, H. T., Hirota, S., Kitamura, Y. & Tanaka, K., Nov 1 2002, In : DNA Repair. 1, 11, p. 935-940 6 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Skin
Carcinogenesis
Genes
Knockout Mice
2001
83 Citations (Scopus)

Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum group A and Cockayne syndrome group B DNA repair genes

Murai, M., Enokido, Y., Inamura, N., Yoshino, M., Nakatsu, Y., Van Der Horst, G. T. J., Hoeijmakers, J. H. J., Tanaka, K. & Hatanaka, H., Nov 6 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 23, p. 13379-13384 6 p.

Research output: Contribution to journalArticle

Cockayne Syndrome
Xeroderma Pigmentosum
Cerebellar Ataxia
DNA Repair
Genes
1 Citation (Scopus)

Transcription-coupled repair and Cockayne syndrome

Nakatsu, Y., 2001, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 46, 8 Suppl, p. 908-915 8 p.

Research output: Contribution to journalReview article

Cockayne Syndrome
Genetic Transcription
Bacterial Proteins
DNA Repair
Transcription Factors
30 Citations (Scopus)

UV-induced skin carcinogenesis in xeroderma pigmentosum group A (XPA) gene-knockout mice with nucleotide excision repair-deficiency

Tanaka, K., Kamiuchi, S., Ren, Y., Yonemasu, R., Ichikawa, M., Murai, H., Yoshino, M., Takeuchi, S., Saijo, M., Nakatsu, Y., Miyauchi-Hashimoto, H. & Horio, T., Jun 2 2001, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 477, 1-2, p. 31-40 10 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum
Gene Knockout Techniques
Knockout Mice
DNA Repair
Carcinogenesis
2000
43 Citations (Scopus)

A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA

Nitta, M., Saijo, M., Kodo, N., Matsuda, T., Nakatsu, Y., Tamai, H. & Tanaka, K., Nov 1 2000, In : Nucleic acids research. 28, 21, p. 4212-4218 7 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
DNA Repair
Carrier Proteins
Proteins
Two-Hybrid System Techniques
16 Citations (Scopus)

Decreased UV sensitivity, mismatch repair activity and abnormal cell cycle checkpoints in skin cancer cell lines derived from UVB-irradiated XPA-deficient mice

Ichikawa, M., Nakane, H., Marra, G., Corti, C., Jiricny, J., Fitch, M., Ford, J. M., Ikejima, M., Shimada, T., Yoshino, M., Takeuchi, S., Nakatsu, Y. & Tanaka, K., May 31 2000, In : Mutation Research - DNA Repair. 459, 4, p. 285-298 14 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Skin Neoplasms
Cell Cycle Checkpoints
Skin
Repair
21 Citations (Scopus)

Studies of in vivo mutations in rpsL transgene in UVB-irradiated epidermis of XPA-deficient mice

Murai, H., Takeuchi, S., Nakatsu, Y., Ichikawa, M., Yoshino, M., Gondo, Y., Katsuki, M. & Tanaka, K., May 30 2000, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 450, 1-2, p. 181-192 12 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum
Transgenes
Epidermis
Mutation
DNA Repair
90 Citations (Scopus)

XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription

Nakatsu, Y., Asahina, H., Citterio, E., Rademakers, S., Vermeulen, W., Kamiuchi, S., Yeo, J. P., Khaw, M. C., Saijo, M., Kodo, N., Matsuda, T., Hoeijmakers, J. H. J. & Tanaka, K., Nov 10 2000, In : Journal of Biological Chemistry. 275, 45, p. 34931-34937 7 p.

Research output: Contribution to journalArticle

Transcription
DNA Repair
Carrier Proteins
Repair
Genome
1998
84 Citations (Scopus)

A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice

Lehman, A. L., Nakatsu, Y., Ching, A., Bronson, R. T., Oakey, R. J., Keiper-Hrynko, N., Finger, J. N., Durham-Pierre, D., Horton, D. B., Newton, J. M., Lyon, M. F. & Brilliant, M. H., Aug 4 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 16, p. 9436-9441 6 p.

Research output: Contribution to journalArticle

Genes
Proteins
Alleles
Cytochromes a
Hypopigmentation
33 Citations (Scopus)

Mutational analysis of a function of xeroderma pigmentosum group A (XPA) protein in strand-specific DNA repair

Kobayashi, T., Takeuchi, S., Saijo, M., Nakatsu, Y., Morioka, H., Otsuka, E., Wakasugi, M., Nikaido, O. & Tanaka, K., Oct 15 1998, In : Nucleic acids research. 26, 20, p. 4662-4668 7 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum Group A Protein
Pyrimidine Dimers
DNA Repair
Xeroderma Pigmentosum
Transcription Factor TFIIH
4 Citations (Scopus)

RPA2, a gene for the 32 kDa subunit of replication protein A on chromosome 1p35-36, is not mutated in patients with familial melanoma linked to chromosome 1p36

Jing Ping, Y., Nakatsu, Y., Goldstein, A. M., Tucker, M. A., Kraemer, K. H. & Tanaka, K., 1998, In : Melanoma Research. 8, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

Replication Protein A
Chromosomes
Dysplastic Nevus Syndrome
Nevi and Melanomas
Genes
34 Citations (Scopus)

Strand specificity and absence of hot spots for p53 mutations in ultraviolet B-induced skin tumors of XPA-deficient mice

Takeuchi, S., Nakatsu, Y., Nakane, H., Murai, H., Hirota, S., Kitamura, Y., Okuyama, A. & Tanaka, K., Feb 15 1998, In : Cancer Research. 58, 4, p. 641-646 6 p.

Research output: Contribution to journalArticle

Skin
Mutation
Neoplasms
Xeroderma Pigmentosum
Skin Neoplasms
1997
20 Citations (Scopus)

Loss of the xeroderma pigmentosum group A gene (XPA) enhances apoptosis of cultured cerebellar neurons induced by UV but not by low-K+ medium

Enokido, Y., Inamura, N., Araki, T., Satoh, T., Nakane, H., Yoshino, M., Nakatsu, Y., Tanaka, K. & Hatanaka, H., Jul 1 1997, In : Journal of Neurochemistry. 69, 1, p. 246-251 6 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum
Neurons
Genes
Apoptosis
Irradiation
25 Citations (Scopus)

Mutations in the XPD gene leading to xeroderma pigmentosum symptoms

Kobayashi, T., Kuraoka, I., Saijo, M., Nakatsu, Y., Tanaka, A., Someda, Y., Fukuro, S. & Tanaka, K., Apr 22 1997, In : Human Mutation. 9, 4, p. 322-331 10 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum
Mutation
Genes
Inborn Genetic Diseases
Complementary DNA
1996

In vitro and in vivo analysis of the XPA gene

Tanaka, K., Nakatsu, Y., Saijo, M., Kobayashi, T., Matsuda, T., Kuraoka, I., Murai, H., Nakane, H., Takeuchi, S., Kodo, N. & Nitta, M., Dec 1 1996, In : Japanese Journal of Human Genetics. 41, 1, 1 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum
DNA Repair
Genes
Proteins
Carcinogenesis
1995
156 Citations (Scopus)

DNA repair protein XPA binds replication protein A (RPA)

Matsuda, T., Saijo, M., Kuraoka, I., Kobayashi, T., Nakatsu, Y., Nagai, A., Enjoji, T., Masutani, C., Sugasawa, K., Hanaoka, F., Yasui, A. & Tanaka, K., Jan 1 1995, In : Journal of Biological Chemistry. 270, 8, p. 4152-4157 6 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum Group A Protein
Replication Protein A
DNA Repair
DNA
Repair