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Research Output 2002 2019

  • 743 Citations
  • 15 h-Index
  • 40 Article
  • 1 Editorial
  • 1 Review article
2019

Early initiation of a factor Xa inhibitor can attenuate tissue repair and neurorestoration after middle cerebral artery occlusion

Komori, M., Ago, T., Wakisaka, Y., Nakamura, K., Tachibana, M., Yoshikawa, Y., Shibahara, T., Yamanaka, K., Kuroda, J. & Kitazono, T., Sep 1 2019, In : Brain Research. 1718, p. 201-211 11 p.

Research output: Contribution to journalArticle

Peptide Initiation Factors
Middle Cerebral Artery Infarction
Stroke
Nervous System
Monocytes

Nox4 Promotes Neural Stem/Precursor Cell Proliferation and Neurogenesis in the Hippocampus and Restores Memory Function Following Trimethyltin-Induced Injury

Yoshikawa, Y., Ago, T., Kuroda, J., Wakisaka, Y., Tachibana, M., Komori, M., Shibahara, T., Nakashima, H., Nakashima, K. & Kitazono, T., Feb 1 2019, In : Neuroscience. 398, p. 193-205 13 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Neurogenesis
Hippocampus
Cell Proliferation
Wounds and Injuries

Poor glycemic control and posterior circulation ischemic stroke

Kuroda, J., Matsuo, R., Yamaguchi, Y., Sato, N., Kamouchi, M., Hata, J., Wakisaka, Y., Ago, T. & Kitazono, T., Apr 1 2019, In : Neurology: Clinical Practice. 9, 2, p. 129-139 11 p.

Research output: Contribution to journalArticle

Stroke
Propensity Score
Hemoglobins
Glucose
Insulin Resistance

Poor glycemic control and posterior circulation ischemic stroke

Fukuoka Stroke Registry Investigators, Apr 1 2019, In : Neurology: Clinical Practice. 9, 2, p. 129-139 11 p.

Research output: Contribution to journalArticle

Stroke
Propensity Score
Hemoglobins
Glucose
Insulin Resistance
Open Access
Metalloproteases
Biomarkers
Stroke

Quality Management Program of Stroke Rehabilitation Using Adherence to Guidelines: A Nationwide Initiative in Japan

Miura, S., Miyata, R., Matsumoto, S., Higashi, T., Wakisaka, Y., Ago, T., Kitazono, T., Iihara, K. & Shimodozono, M., Sep 2019, In : Journal of Stroke and Cerebrovascular Diseases. 28, 9, p. 2434-2441 8 p.

Research output: Contribution to journalArticle

Guideline Adherence
Japan
Rehabilitation
Medicine
Quality of Health Care
2018
1 Citation (Scopus)

Association of Embolic Sources With Cause-Specific Functional Outcomes Among Adults With Cryptogenic Stroke

Fukuoka Stroke Registry Investigators, Sep 7 2018, In : JAMA network open. 1, 5, p. e182953

Research output: Contribution to journalArticle

Open Access
Stroke
Paradoxical Embolism
Embolism
Registries
National Institutes of Health (U.S.)

Association of Embolic Sources With Cause-Specific Functional Outcomes Among Adults With Cryptogenic Stroke

Fukuoka Stroke Registry Investigators, Sep 7 2018, In : JAMA network open. 1, 5, p. e182953

Research output: Contribution to journalArticle

Stroke
Paradoxical Embolism
Embolism
Registries
National Institutes of Health (U.S.)
8 Citations (Scopus)

Insulin resistance and clinical outcomes after acute ischemic stroke

Ago, T., Matsuo, R., Hata, J., Wakisaka, Y., Kuroda, J., Kitazono, T. & Kamouchi, M., Jan 1 2018, In : Neurology. 90, 17, p. E1470-E1477

Research output: Contribution to journalArticle

Insulin Resistance
Stroke
Homeostasis
Recurrence
Nervous System

Insulin resistance and clinical outcomes after acute ischemic stroke

Fukuoka Stroke Registry Investigators, Apr 24 2018, In : Neurology. 90, 17, p. e1470-e1477

Research output: Contribution to journalArticle

Insulin Resistance
Stroke
Homeostasis
Recurrence
Nervous System
2 Citations (Scopus)

Safety of antithrombotic therapy for patients with acute ischemic stroke harboring unruptured intracranial aneurysm

Shono, Y., Sugimori, H., Matsuo, R., Fukushima, Y., Wakisaka, Y., Kuroda, J., Ago, T., Kamouchi, M. & Kitazono, T., Oct 1 2018, In : International Journal of Stroke. 13, 7, p. 734-742 9 p.

Research output: Contribution to journalArticle

Intracranial Aneurysm
Stroke
Safety
Therapeutics
Fibrinolytic Agents
2017
4 Citations (Scopus)
Dementia
Registries
Stroke
Propensity Score
Logistic Models
6 Citations (Scopus)

Association between onset-to-door time and clinical outcomes after ischemic stroke

Matsuo, R., Yamaguchi, Y., Matsushita, T., Hata, J., Kiyuna, F., Fukuda, K., Wakisaka, Y., Kuroda, J., Ago, T., Kitazono, T., Kamouchi, M., Ishitsuka, T., Ibayashi, S., Kusuda, K., Fujii, K., Nagao, T., Okada, Y., Yasaka, M., Ooboshi, H., Irie, K. & 9 others, Omae, T., Toyoda, K., Nakane, H., Sugimori, H., Arakawa, S., Kitayama, J., Fujimoto, S., Arihiro, S. & Fukushima, Y., Nov 2017, In : Stroke. 48, 11, p. 3049-3056 8 p.

Research output: Contribution to journalArticle

Stroke
Reperfusion
National Institutes of Health (U.S.)
Therapeutics
Japan
15 Citations (Scopus)

Early Reperfusion after Brain Ischemia Has Beneficial Effects beyond Rescuing Neurons

Tachibana, M., Ago, T., Wakisaka, Y., Kuroda, J., Shijo, M., Yoshikawa, Y., Komori, M., Nishimura, A., Makihara, N., Nakamura, K. & Kitazono, T., Aug 1 2017, In : Stroke. 48, 8, p. 2222-2230 9 p.

Research output: Contribution to journalArticle

Brain Ischemia
Reperfusion
Neurons
Microtubule-Associated Proteins
Ischemia
10 Citations (Scopus)

Left atrial size and long-term risk of recurrent stroke after acute ischemic stroke in patients with nonvalvular atrial fibrillation

on behalf of the FSR Investigators, Aug 1 2017, In : Journal of the American Heart Association. 6, 8, e006402.

Research output: Contribution to journalArticle

Atrial Fibrillation
Stroke
Recurrence
Body Surface Area
Anticoagulants
1 Citation (Scopus)

Repeated Paradoxical Brain Infarctions in a Patient on Self-Managed Home Hemodialysis Using a Long-Term Indwelling Catheter

Kiyohara, T., Mizoguchi, T., Kuroda, J., Wakisaka, Y., Irie, A., Kitaoka, C., Fujisaki, K., Nakamura, U., Tsuruya, K., Kitazono, T. & Ago, T., Sep 2017, In : Journal of Stroke and Cerebrovascular Diseases. 26, 9, p. e183-e185

Research output: Contribution to journalArticle

Home Hemodialysis
Brain Infarction
Indwelling Catheters
Patent Foramen Ovale
Catheters
2016
24 Citations (Scopus)

Detrimental role of pericyte Nox4 in the acute phase of brain ischemia

Nishimura, A., Ago, T., Kuroda, J., Arimura, K., Tachibana, M., Nakamura, K., Wakisaka, Y., Sadoshima, J., Iihara, K. & Kitazono, T., Jun 1 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, 6, p. 1143-1154 12 p.

Research output: Contribution to journalArticle

Pericytes
Brain Ischemia
Middle Cerebral Artery Infarction
Blood-Brain Barrier
Matrix Metalloproteinase 9
7 Citations (Scopus)

Influence of Statin Pretreatment on Initial Neurological Severity and Short-Term Functional Outcome in Acute Ischemic Stroke Patients: The Fukuoka Stroke Registry

behalf of the Fukuoka Stroke Registry Investigators, Nov 1 2016, In : Cerebrovascular Diseases. 42, 5-6, p. 395-403 9 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Registries
Stroke
Therapeutics
Logistic Models
14 Citations (Scopus)

Plasma C-reactive protein and clinical outcomes after acute ischemic stroke: A prospective observational study

Fukuoka Stroke Registry Investigators, Jun 1 2016, In : PloS one. 11, 6, e0156790.

Research output: Contribution to journalArticle

C-reactive protein
observational studies
stroke
C-Reactive Protein
blood proteins
19 Citations (Scopus)

Possible involvement of basic FGF in the upregulation of PDGFRβ in pericytes after ischemic stroke

Nakamura, K., Arimura, K., Nishimura, A., Tachibana, M., Yoshikawa, Y., Makihara, N., Wakisaka, Y., Kuroda, J., Kamouchi, M., Ooboshi, H., Kitazono, T. & Ago, T., Jan 1 2016, In : Brain Research. 1630, p. 98-108 11 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Pericytes
Fibroblast Growth Factor 2
Up-Regulation
Stroke
2015

An update on novel oral anticoagulants

Ago, T., Wakisaka, Y. & Kuroda, J., Jan 1 2015, In : Japanese Journal of Neurosurgery. 24, 4, p. 220-225 6 p.

Research output: Contribution to journalArticle

Anticoagulants
Stroke
Atrial Fibrillation
Therapeutics
35 Citations (Scopus)
Platelet-Derived Growth Factor Receptors
Extracellular Matrix Proteins
Fibrosis
Collagen Type I
Stroke
24 Citations (Scopus)

Sex differences in short-term outcomes after acute ischemic stroke: The fukuoka stroke registry

Irie, F., Kamouchi, M., Hata, J., Matsuo, R., Wakisaka, Y., Kuroda, J., Ago, T., Kitazono, T., Ishitsuka, T., Fujimoto, S., Ibayashi, S., Kusuda, K., Arakawa, S., Tamaki, K., Sadoshima, S., Irie, K., Fujii, K., Okada, Y., Yasaka, M., Nagao, T. & 7 others, Ooboshi, H., Omae, T., Toyoda, K., Nakane, H., Sugimori, H., Fukuda, K. & Fukushima, Y., Feb 6 2015, In : Stroke. 46, 2, p. 471-476 6 p.

Research output: Contribution to journalArticle

Sex Characteristics
Registries
Stroke
National Institutes of Health (U.S.)
Japan
2014
1 Citation (Scopus)
Registries
Stroke
Recurrence
Genotype
Single Nucleotide Polymorphism
13 Citations (Scopus)

Intravenous thrombolysis with recombinant tissue plasminogen activator for ischemic stroke patients over 80 years old: The Fukuoka Stroke Registry

FSR Investigators, Oct 16 2014, In : PloS one. 9, 10, e110444.

Research output: Contribution to journalArticle

t-plasminogen activator
Tissue Plasminogen Activator
stroke
Registries
Stroke
34 Citations (Scopus)

Nox4 is a major source of superoxide production in human brain pericytes

Kuroda, J., Ago, T., Nishimura, A., Nakamura, K., Matsuo, R., Wakisaka, Y., Kamouchi, M. & Kitazono, T., Mar 6 2014, In : Journal of Vascular Research. 51, 6, p. 429-438 10 p.

Research output: Contribution to journalArticle

Pericytes
Superoxides
Brain
Reactive Oxygen Species
Angiotensin II
13 Citations (Scopus)

Plasma S100A12 is associated with functional outcome after ischemic stroke: Research for Biomarkers in Ischemic Stroke

Wakisaka, Y., Ago, T., Kamouchi, M., Kuroda, J., Matsuo, R., Hata, J., Gotoh, S., Isomura, T., Awano, H., Suzuki, K., Fukuda, K., Okada, Y., Kiyohara, Y., Ooboshi, H. & Kitazono, T., May 15 2014, In : Journal of the Neurological Sciences. 340, 1-2, p. 75-79 5 p.

Research output: Contribution to journalArticle

Biomarkers
Stroke
Research
Granulocytes
Brain Injuries
10 Citations (Scopus)

Thrombolytic therapy for stroke in patients with preexisting cognitive impairment

Murao, K., Leys, D., Jacquin, A., Kitazono, T., Bordet, R., Béjot, Y., Kimura, K., Godefroy, O., Wakisaka, Y., Moulin, S., Ago, T., Sibon, I., Bombois, S., Mas, J. L., Hénon, H., Pasquier, F., Giroud, M., Cordonnier, C. & Okada, Y., Jun 10 2014, In : Neurology. 82, 23, p. 2048-2054 7 p.

Research output: Contribution to journalArticle

Thrombolytic Therapy
Stroke
Tissue Plasminogen Activator
Cerebral Hemorrhage
Odds Ratio
6 Citations (Scopus)
Thrombolytic Therapy
Tissue Plasminogen Activator
stroke
Registries
confidence
2013
3 Citations (Scopus)

Slowly progressive and painless thoracic aortic dissection presenting with a persistent fever in an elderly patient: The usefulness of combined measurement of biochemical parameters

Yamada, S., Tokumoto, M., Ohkuma, T., Kansui, Y., Wakisaka, Y., Uchizono, Y., Tsuruya, K., Kitazono, T. & Ooboshi, H., Jan 1 2013, In : Case Reports in Medicine. 2013, 498129.

Research output: Contribution to journalArticle

Dissection
Fever
Thorax
Chest Pain
Fever of Unknown Origin
2010
25 Citations (Scopus)

Critical role for copper/zinc-superoxide dismutase in preventing spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice

Wakisaka, Y., Chu, Y., Miller, J. D., Rosenberg, G. A. & Heistad, D. D., Apr 1 2010, In : Stroke. 41, 4, p. 790-797 8 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Superoxide Dismutase
Zinc
Copper
Superoxides
65 Citations (Scopus)

Spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice

Wakisaka, Y., Chu, Y., Miller, J. D., Rosenberg, G. A. & Heistad, D. D., Jan 1 2010, In : Journal of Cerebral Blood Flow and Metabolism. 30, 1, p. 56-69 14 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Hypertension
Oxidative Stress
Angiotensin II
Matrix Metalloproteinases
2009
105 Citations (Scopus)

Novel aspects of oxidative stress in cardiovascular diseases

Heistad, D. D., Wakisaka, Y., Miller, J., Chu, Y. & Pena-Silva, R., Feb 10 2009, In : Circulation Journal. 73, 2, p. 201-207 7 p.

Research output: Contribution to journalReview article

Reactive Oxygen Species
Oxidative Stress
Cardiovascular Diseases
Antioxidants
Stroke
2008
43 Citations (Scopus)

Clinicopathological outline of dementia with Lewy bodies applying the revised criteria: The Hisayama study

Fujimi, K., Sasaki, K., Noda, K., Wakisaka, Y., Tanizaki, Y., Matsui, Y., Sekita, A., Iida, M., Kiyohara, Y., Kanba, S. & Iwaki, T., Jul 1 2008, In : Brain Pathology. 18, 3, p. 317-325 9 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Lewy Bodies
Pathology
Brain Stem
Autopsy
21 Citations (Scopus)

Oxidative stress through activation of NAD(P)H oxidase in hypertensive mice with spontaneous intracranial hemorrhage

Wakisaka, Y., Miller, J. D., Chu, Y., Baumbach, G. L., Wilson, S., Faraci, F. M., Sigmund, C. D. & Heistad, D. D., Jun 30 2008, In : Journal of Cerebral Blood Flow and Metabolism. 28, 6, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

Intracranial Hemorrhages
NADPH Oxidase
Oxidative Stress
NG-Nitroarginine Methyl Ester
Superoxides
2007
26 Citations (Scopus)

Altered expression of COX-2 in subdivisions of the hippocampus during aging and in Alzheimer's disease: The Hisayama study

Fujimi, K., Noda, K., Sasaki, K., Wakisaka, Y., Tanizaki, Y., Iida, M., Kiyohara, Y., Kanba, S. & Iwaki, T., May 1 2007, In : Dementia and Geriatric Cognitive Disorders. 23, 6, p. 423-431 9 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Hippocampus
Alzheimer Disease
Pathology
Brain
2006
10 Citations (Scopus)

Increased asymmetric pulvinar magnetic resonance imaging signals in Creutzfeldt-Jakob disease with florid plaques following a cadaveric dura mater graft

Wakisaka, Y., Santa, N., Doh-ura, K., Kitamoto, T., Ibayashi, S., Iida, M. & Iwaki, T., Feb 1 2006, In : Neuropathology. 26, 1, p. 82-88 7 p.

Research output: Contribution to journalArticle

Pulvinar
Dura Mater
Creutzfeldt-Jakob Syndrome
Magnetic Resonance Imaging
Transplants
34 Citations (Scopus)

Quantitative analysis of neurofibrillary pathology in a general population to reappraise neuropathological criteria for senile dementia of the neurofibrillary tangle type (tangle-only dementia): The Hisayama study

Noda, K., Sasaki, K., Fujimi, K., Wakisaka, Y., Tanizaki, Y., Wakugawa, Y., Kiyohara, Y., Iida, M., Aizawa, H. & Iwaki, T., Dec 1 2006, In : Neuropathology. 26, 6, p. 508-518 11 p.

Research output: Contribution to journalArticle

Neurofibrillary Tangles
Dementia
Alzheimer Disease
Pathology
Population
2005
8 Citations (Scopus)

Fatal familial insomnia with an unusual prion protein deposition pattern: An autopsy report with an experimental transmission study

Sasaki, K., Doh-Ura, K., Wakisaka, Y., Tomoda, H. & Iwaki, T., Feb 1 2005, In : Neuropathology and Applied Neurobiology. 31, 1, p. 80-87 8 p.

Research output: Contribution to journalArticle

Fatal Familial Insomnia
Autopsy
Cerebral Cortex
Olivary Nucleus
Cerebellar Ataxia
2003
75 Citations (Scopus)

Age-associated prevalence and risk factors of Lewy body pathology in a general population: The Hisayama study

Wakisaka, Y., Furuta, A., Tanizaki, Y., Kiyohara, Y., Iida, M. & Iwaki, T., Oct 1 2003, In : Acta neuropathologica. 106, 4, p. 374-382 9 p.

Research output: Contribution to journalArticle

Lewy Bodies
Pathology
Lewy Body Disease
Population
Alzheimer Disease
30 Citations (Scopus)

Cellular Distribution of NDRG1 Protein in the Rat Kidney and Brain during Normal Postnatal Development

Wakisaka, Y., Furuta, A., Masuda, K., Morikawa, W., Kuwano, M. & Iwaki, T., Nov 2003, In : Journal of Histochemistry and Cytochemistry. 51, 11, p. 1515-1525 11 p.

Research output: Contribution to journalArticle

myc Genes
Down-Regulation
Kidney
Brain
Proteins
2002
51 Citations (Scopus)

Clusterin/apolipoprotein J is associated with cortical Lewy bodies: Immunohistochemical study in cases with α-synucleinopathies

Sasaki, K., Doh-ura, K., Wakisaka, Y. & Iwaki, T., Dec 1 2002, In : Acta neuropathologica. 104, 3, p. 225-230 6 p.

Research output: Contribution to journalArticle

Clusterin
Lewy Bodies
Synucleins
Inclusion Bodies
Lewy Body Disease