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Fingerprint Dive into the research topics where Yuichi Tsukada is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Histones Medicine & Life Sciences
Histone Demethylases Medicine & Life Sciences
Hepatocyte Growth Factor Medicine & Life Sciences
Methylation Medicine & Life Sciences
Hep G2 Cells Medicine & Life Sciences
Histone Code Medicine & Life Sciences
Hepatocellular Carcinoma Medicine & Life Sciences
Jumonji Domain-Containing Histone Demethylases Medicine & Life Sciences

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Research Output 2001 2019

  • 3071 Citations
  • 16 h-Index
  • 19 Article
  • 2 Review article

Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression

Nakatsukasa, H., Oda, M., Yin, J., Chikuma, S., Ito, M., Koga-Iizuka, M., Someya, K., Kitagawa, Y., Ohkura, N., Sakaguchi, S., Koya, I., Sanosaka, T., Kohyama, J., Tsukada, Y., Yamanaka, S., Takamura-Enya, T., Lu, Q. & Yoshimura, A., Jan 1 2019, In : International Immunology. 31, 5, p. 335-347 13 p.

Research output: Contribution to journalArticle

Interleukin-17
Protein Transport
Regulatory T-Lymphocytes
Immunoglobulin G
5-Methylcytosine
10 Citations (Scopus)

Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation

Someya, K., Nakatsukasa, H., Ito, M., Kondo, T., Tateda, K. I., Akanuma, T., Koya, I., Sanosaka, T., Kohyama, J., Tsukada, Y., Takamura-Enya, T. & Yoshimura, A., Aug 1 2017, In : International Immunology. 29, 8, p. 365-375 11 p., dxx049.

Research output: Contribution to journalArticle

Enzyme Induction
Enzyme Activation
Catalytic Domain
5-Methylcytosine
Oxygen
34 Citations (Scopus)

Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons

Hatanaka, Y., Inoue, K., Oikawa, M., Kamimura, S., Ogonuki, N., Kodama, E. N., Ohkawa, Y., Tsukada, Y. & Ogura, A., Nov 24 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 47, p. 14641-14646 6 p.

Research output: Contribution to journalArticle

Chromatin Assembly Factor-1
Histone Code
Histone Chaperones
Retroelements
Blastocyst
18 Citations (Scopus)

Maternal TET3 is dispensable for embryonic development but is required for neonatal growth

Tsukada, Y., Akiyama, T. & Nakayama, K., Oct 28 2015, In : Scientific reports. 5, 15876.

Research output: Contribution to journalArticle

5-Methylcytosine
Zygote
Embryonic Development
Mothers
DNA Methylation
49 Citations (Scopus)

Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity

Suzuki, T., Ozasa, H., Itoh, Y., Zhan, P., Sawada, H., Mino, K., Walport, L., Ohkubo, R., Kawamura, A., Yonezawa, M., Tsukada, Y., Tumber, A., Nakagawa, H., Hasegawa, M., Sasaki, R., Mizukami, T., Schofield, C. J. & Miyata, N., Sep 26 2013, In : Journal of Medicinal Chemistry. 56, 18, p. 7222-7231 10 p.

Research output: Contribution to journalArticle

Histone Demethylases
Enzyme Assays
Antineoplastic Agents
Histones
Lysine