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Research Output

Applicability of the Øie-Tozer model to predict three types of distribution volume (Vd) in humans: Vd in central compartment, Vd at steady state, and Vd at beta phase

Yahata, M., Ishii, Y., Nakagawa, T., Watanabe, T. & Miyawaki, I., Apr 1 2020, In : Biopharmaceutics and Drug Disposition. 41, 4-5, p. 151-165 15 p.

Research output: Contribution to journalArticle

  • Gestational dioxin exposure suppresses prolactin-stimulated nursing in lactating dam rats to impair development of postnatal offspring

    Takeda, T., Fujii, M., Izumoto, W., Hattori, Y., Matsushita, T., Yamada, H. & Ishii, Y., Aug 2020, In : Biochemical Pharmacology. 178, 114106.

    Research output: Contribution to journalArticle

  • Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT

    Miyauchi, Y., Kurita, A., Yamashita, R., Takamatsu, T., Ikushiro, S., Mackenzie, P. I., Tanaka, Y. & Ishii, Y., Apr 30 2020, In : Biochemical and Biophysical Research Communications. 525, 2, p. 348-353 6 p.

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    UDP-Glucuronosyltransferase (UGT)-mediated attenuations of cytochrome P450 3A4 activity: UGT isoform-dependent mechanism of suppression

    Miyauchi, Y., Tanaka, Y., Nagata, K., Yamazoe, Y., Mackenzie, P. I., Yamada, H. & Ishii, Y., Mar 1 2020, In : British Journal of Pharmacology. 177, 5, p. 1077-1089 13 p.

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)