β-alanine enhances brain and muscle carnosine levels in broiler chicks

Shozo Tomonaga, Mitsuhito Matsumoto, Mitsuhiro Furuse

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Carnosine and its methylated derivative anserine are dipeptides present in high levels in chicken muscles. They are antioxidants and putative neurotransmitters. If administration of β-alanine, one of the constituents of carnosine, could increase levels of these dipeptides in the brain and muscles, it may improve brain function and increase commercial values of the chicken meat. In the present study, we investigated whether orally administered β-alanine could increase these dipeptide levels in the brain, Musculus pectoralis superficialis, and plasma in broiler chicks. Broilers (2 days old) were given oral doses of β-alanine (0.176, 0.88, 4.4 and 22 mmol/kg) twice a day for 5 days. Carnosine levels were dose-dependently increased in the brain, Musculus pectoralis superficialis, and plasma while no influence of anserine was detected. These results suggest that supplemental β-alanine could be effective in increasing carnosine levels in the brain and muscle of broiler chicks.

Original languageEnglish
Pages (from-to)308-312
Number of pages5
JournalJournal of Poultry Science
Volume49
Issue number4
DOIs
Publication statusPublished - Jan 1 2012

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carnosine
alanine
broiler chickens
dipeptides
brain
muscles
anserine
chicken meat
dosage
neurotransmitters
mouth
chickens
antioxidants

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology

Cite this

β-alanine enhances brain and muscle carnosine levels in broiler chicks. / Tomonaga, Shozo; Matsumoto, Mitsuhito; Furuse, Mitsuhiro.

In: Journal of Poultry Science, Vol. 49, No. 4, 01.01.2012, p. 308-312.

Research output: Contribution to journalArticle

Tomonaga, Shozo ; Matsumoto, Mitsuhito ; Furuse, Mitsuhiro. / β-alanine enhances brain and muscle carnosine levels in broiler chicks. In: Journal of Poultry Science. 2012 ; Vol. 49, No. 4. pp. 308-312.
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