(Chemical Equation Presented) Making the right substitution: A remarkable acceleration effect of phenyl-substituted silyl groups in hydroalumination and carbolithiation reactions of propargylic alcohols (see formula) is described. The results show that an aryl silyl group can act not only as a protecting group but also as an activating group of the alkynyl moiety. This work provides an efficient group-selective approach to multifunctionalized alkenes.
|Number of pages||3|
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - Dec 23 2005|
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