TY - JOUR
T1 - ζ-COP, a subunit of coatomer, is required for COP-coated vesicle assembly
AU - Kuge, O.
AU - Hara-Kuge, S.
AU - Orci, L.
AU - Ravazzola, M.
AU - Amherdt, M.
AU - Tanigawa, G.
AU - Wieland, F. T.
AU - Rothman, J. E.
PY - 1993
Y1 - 1993
N2 - cDNA encoding the 20-kD subunit of coatomer, ζ-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to ζ-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP- coated vesicles on Golgi cisternae. Unlike other coatomer subunits (β-, β'- , γ-, and ε-COP), ζ-COP exists in both coatomer bound and free pools.
AB - cDNA encoding the 20-kD subunit of coatomer, ζ-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to ζ-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP- coated vesicles on Golgi cisternae. Unlike other coatomer subunits (β-, β'- , γ-, and ε-COP), ζ-COP exists in both coatomer bound and free pools.
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U2 - 10.1083/jcb.123.6.1727
DO - 10.1083/jcb.123.6.1727
M3 - Article
C2 - 8276893
AN - SCOPUS:0027752244
SN - 0021-9525
VL - 123
SP - 1727
EP - 1734
JO - Journal of Cell Biology
JF - Journal of Cell Biology
IS - 6 II
ER -