(η6-arene)RuII/chiral SN ligand: A novel bifunctional catalyst system for asymmetric transfer hydrogenation of aromatic ketones

Masato Ito, Yuji Shibata, Akira Watanabe, Takao Ikariya

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A binary catalyst system of [RuCl26-arene)] 2 and a protic aminothiol (SN) ligand has been found to promote hydrogen transfer between alcohols and carbonyl compounds. The chiral catalyst system with the pipecolinol-derived chiral SN ligand displays excellent stereoselectivity in the asymmetric transfer hydrogenation of aromatic ketones using HCO2H-Et3N. Novel unsymmetrical bis(thiolate)- bridged binuclear complex, which is relevant to the generation of catalytically active species, has been synthesized and structurally characterized.

Original languageEnglish
Pages (from-to)1621-1626
Number of pages6
JournalSynlett
Issue number10
DOIs
Publication statusPublished - Jun 1 2009
Externally publishedYes

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Ketones
Hydrogenation
Ligands
Stereoselectivity
Carbonyl compounds
Catalysts
Hydrogen
Alcohols

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

(η6-arene)RuII/chiral SN ligand : A novel bifunctional catalyst system for asymmetric transfer hydrogenation of aromatic ketones. / Ito, Masato; Shibata, Yuji; Watanabe, Akira; Ikariya, Takao.

In: Synlett, No. 10, 01.06.2009, p. 1621-1626.

Research output: Contribution to journalArticle

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