μ-hydroxo-μ-phenolato dinuclear nickel(II) complexes in a mixed-spin state and their urea adduct as relevance to the urease active site

Rie Amase, Hitomi Shiraishi, Yuji Miyasato, Masaaki Ohba, Hisashi Okawa

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Abstract

Dinucleating compartmental ligands (2,6-bis{N-[(2-dimethylamino)ethyl] iminomethyl}-4-methylphenol (HL 1) and 2-{N-[(2-dimethylamino)ethyl] iminomethyl}-6-{N-methyl-N-[2-(dimethylamino)ethyl]aminomethyl}-4-methylphenol (HL 2)) have afforded the following dinuclear nickel(II) complexes: [Ni 2(L 1)(OH)(py)(H 2O)](ClO 4) 2·H 2O (1), [Ni 2(L 2)(OH)(MeOH) (H 2O)](ClO 4) 2·CH 3CN (2), and [Ni 2(L 2)(OH)(dmf) 2](ClO 4) 2 (3). X-ray crystallographic studies for 1 and 3 have clarified a μ-hydroxo-μ-phenolato dinuclear structure in a mixed-spin state with one pseudo octahedral Ni(II) (S = 1) and one planar Ni(II) (S = 0). The urea adducts, [Ni 2(L 1)(OH)(urea)(H 2O)](ClO 4) 2·H 2O (1′) and [Ni 2(L 2)(OH)(urea)(H 2O)](ClO 4) 2 (2′), were prepared by the reaction of 1 and 2 with urea, respectively, and were structurally characterized to be in the mixed-spin state. The relevance of 1′ and 2′ to urease is discussed.

Original languageEnglish
Pages (from-to)1814-1820
Number of pages7
JournalBulletin of the Chemical Society of Japan
Volume78
Issue number10
DOIs
Publication statusPublished - Dec 1 2005

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Urease
Nickel
Urea
Ligands
X rays
4-cresol

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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μ-hydroxo-μ-phenolato dinuclear nickel(II) complexes in a mixed-spin state and their urea adduct as relevance to the urease active site. / Amase, Rie; Shiraishi, Hitomi; Miyasato, Yuji; Ohba, Masaaki; Okawa, Hisashi.

In: Bulletin of the Chemical Society of Japan, Vol. 78, No. 10, 01.12.2005, p. 1814-1820.

Research output: Contribution to journalArticle

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AU - Ohba, Masaaki

AU - Okawa, Hisashi

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N2 - Dinucleating compartmental ligands (2,6-bis{N-[(2-dimethylamino)ethyl] iminomethyl}-4-methylphenol (HL 1) and 2-{N-[(2-dimethylamino)ethyl] iminomethyl}-6-{N-methyl-N-[2-(dimethylamino)ethyl]aminomethyl}-4-methylphenol (HL 2)) have afforded the following dinuclear nickel(II) complexes: [Ni 2(L 1)(OH)(py)(H 2O)](ClO 4) 2·H 2O (1), [Ni 2(L 2)(OH)(MeOH) (H 2O)](ClO 4) 2·CH 3CN (2), and [Ni 2(L 2)(OH)(dmf) 2](ClO 4) 2 (3). X-ray crystallographic studies for 1 and 3 have clarified a μ-hydroxo-μ-phenolato dinuclear structure in a mixed-spin state with one pseudo octahedral Ni(II) (S = 1) and one planar Ni(II) (S = 0). The urea adducts, [Ni 2(L 1)(OH)(urea)(H 2O)](ClO 4) 2·H 2O (1′) and [Ni 2(L 2)(OH)(urea)(H 2O)](ClO 4) 2 (2′), were prepared by the reaction of 1 and 2 with urea, respectively, and were structurally characterized to be in the mixed-spin state. The relevance of 1′ and 2′ to urease is discussed.

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