11-Ketotestosterone (11-KT) is considered a potent male-specific androgen in teleost fish. It has important roles in sex characteristic development, spermatogenesis, and male reproductive behavior. Recently, 11KT was identified as an active androgen in other vertebrates. 11-KT mediates these effects through the androgen receptor (AR), a member of the nuclear receptor superfamily. Liganded AR regulates the transcription of androgen-responsive genes.
|Title of host publication||Handbook of Hormones|
|Subtitle of host publication||Comparative Endocrinology for Basic and Clinical Research|
|Number of pages||2|
|Publication status||Published - Jan 1 2021|
All Science Journal Classification (ASJC) codes