TY - JOUR
T1 - 1,1,4,7,10,10-Hexamethyltriethylenetetramine
T2 - A reagent to enhance the rate of alkylation reaction of the lithium enolate of 1-tetralone with alkyl halides
AU - Goto, Mariko
AU - Akimoto, Koh ichi
AU - Aoki, Kazumasa
AU - Shindo, Mitsuru
AU - Koga, Kenji
PY - 1999/11/12
Y1 - 1999/11/12
N2 - The rate of the reaction of the lithium enolate of 1-tetralone with alkyl halides was enhanced greatly in the presence of 3 equivalents of 1,1,4,7,10,10-hexamethyltriethylenetetramine. The ratio of the monoalkylated product to the dialkylated product was found to have increased under a shorter reaction time.
AB - The rate of the reaction of the lithium enolate of 1-tetralone with alkyl halides was enhanced greatly in the presence of 3 equivalents of 1,1,4,7,10,10-hexamethyltriethylenetetramine. The ratio of the monoalkylated product to the dialkylated product was found to have increased under a shorter reaction time.
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U2 - 10.1016/S0040-4039(99)01721-9
DO - 10.1016/S0040-4039(99)01721-9
M3 - Article
AN - SCOPUS:0033550194
VL - 40
SP - 8129
EP - 8132
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 46
ER -