3D rotation of oocyte based on vibration-induced flow control integrated with label-free polarizing observation

Takeshi Hayakawa, Shinya Sakuma, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a novel 3D cell rotation method based on a vibration-induced flow. By applying circular vibration to a microchip having micropillar patterns, local flow is induced around each micropillar. Thus, we can induce the rotational flow when we pattern three micropillars in triangular configuration and the rotational flow can be utilized for rotational manipulation of cells. Additionally, we can achieve the rotation in vertical direction by applying circular vibration in vertical direction. Furthermore, we integrated polarizing microscopy to the rotation system for label-free observation of internal structure of oocytes. We succeeded in rotation of oocyte with 63.7 degrees/s and demonstrated polarizing observation of oocyte.

Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages32-34
Number of pages3
ISBN (Electronic)9780979806483
Publication statusPublished - 2015
Externally publishedYes
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: Oct 25 2015Oct 29 2015

Publication series

NameMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
CountryKorea, Republic of
CityGyeongju
Period10/25/1510/29/15

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Fingerprint Dive into the research topics of '3D rotation of oocyte based on vibration-induced flow control integrated with label-free polarizing observation'. Together they form a unique fingerprint.

Cite this