6-Amino-6-deoxychitosan. Preparation and application as plasmid vector in COS-1 cells

Taku Satoh, Takeshi Nagasaki, Nobuo Sakairi, Seiji Shinkai

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

6-Amino-6-deoxychitosan was prepared from 6-deoxy-6-halo-N- phthaloylchitosan via 6-azidation. The product has high stereoregularity because of the effective and regioselective reactions. To evaluate 6-amino-6- deoxychitosan as a gene transfer agent, transfection efficiencies of its complexes with plasmid DNA in COS-1 cells were examined.

Original languageEnglish
Pages (from-to)340-341
Number of pages2
JournalChemistry Letters
Volume33
Issue number3
DOIs
Publication statusPublished - Mar 1 2004

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Plasmids
Gene transfer
DNA
6-amino-6-deoxy-chitosan
N-phthaloylchitosan

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

6-Amino-6-deoxychitosan. Preparation and application as plasmid vector in COS-1 cells. / Satoh, Taku; Nagasaki, Takeshi; Sakairi, Nobuo; Shinkai, Seiji.

In: Chemistry Letters, Vol. 33, No. 3, 01.03.2004, p. 340-341.

Research output: Contribution to journalArticle

Satoh, Taku ; Nagasaki, Takeshi ; Sakairi, Nobuo ; Shinkai, Seiji. / 6-Amino-6-deoxychitosan. Preparation and application as plasmid vector in COS-1 cells. In: Chemistry Letters. 2004 ; Vol. 33, No. 3. pp. 340-341.
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