8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

Neuroscience

• Neuron 100%
• Mitochondrial DNA 80%
• Neuritogenesis 80%
• Antioxidant 60%
• DNA 40%
• Neurodegenerative Disorder 40%
• 8-Oxoguanine 40%
• Brain 20%
• Neurodegeneration 20%
• In Vitro 20%
• Oxidative Stress 20%
• Neurite Outgrowth 20%
• Cytosine 20%
• Neurite 20%
• Deoxyguanosine Triphosphate 20%
• Pyrophosphate 20%

Biochemistry, Genetics and Molecular Biology

• Mitochondrial DNA 80%
• Mouse 60%
• Wild Type 40%
• Oxidative Stress 20%
• Aging 20%
• Enzymatic Hydrolysis 20%
• Cytosine 20%
• Neurite Outgrowth 20%
• Pyrophosphate 20%
• Deoxyguanosine Triphosphate 20%