Find Research Outputs

Review article
45 Citations (Scopus)

The role of redox modulation of class II histone deacetylases in mediating pathological cardiac hypertrophy

Oka, S. I., Ago, T., Kitazono, T., Zablocki, D. & Sadoshima, J., Aug 1 2009, In : Journal of Molecular Medicine. 87, 8, p. 785-791 7 p.

Research output: Contribution to journalReview article

Histone Deacetylases
Cardiomegaly
Oxidation-Reduction
Thioredoxins
Cell Nucleus Active Transport

The role of serine/threonine kinase, protein kinase D, in thymocyte development

Ishikawa, E. & Yamasaki, S., Jan 1 2017, In : Seikagaku. 89, 5, p. 748-751 4 p.

Research output: Contribution to journalReview article

protein kinase D
99 Citations (Scopus)

The role of sirtuins in cardiac disease

Matsushima, S. & Sadoshima, J., Jan 1 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 9, p. H1375-H1389

Research output: Contribution to journalReview article

Sirtuins
Heart Diseases
Histone Deacetylases
Cardiomegaly
Histone Code
28 Citations (Scopus)

The role of Smads in BMP signaling

Nishimura, R., Hata, K., Ikeda, F., Matsubara, T., Yamashita, K., Ichida, F. & Yoneda, T., Jan 1 2003, In : Frontiers in Bioscience. 8, SUPPL.

Research output: Contribution to journalReview article

Smad Proteins
Bone Morphogenetic Proteins
Organogenesis
Transforming Growth Factors
Osteogenesis
3 Citations (Scopus)

The role of telomere binding molecules for normal and abnormal hematopoiesis

Hosokawa, K. & Arai, F., Jun 1 2018, In : International journal of hematology. 107, 6, p. 646-655 10 p.

Research output: Contribution to journalReview article

Telomere
Hematopoiesis
Hematopoietic Stem Cells
Hematopoietic System
DNA Damage
14 Citations (Scopus)

The role of TFAM-associated proteins in mitochondrial RNA metabolism

Uchiumi, T. & Kang, D., May 1 2012, In : Biochimica et Biophysica Acta - General Subjects. 1820, 5, p. 565-570 6 p.

Research output: Contribution to journalReview article

Mitochondrial DNA
Metabolism
Biochemistry
Small Ribosome Subunits
Proteins
261 Citations (Scopus)

The role of the electric field in confinement

Itoh, K. & Itoh, S. I., Dec 1 1996, In : Plasma Physics and Controlled Fusion. 38, 1, p. 1-49 49 p.

Research output: Contribution to journalReview article

Electric field effects
Plasma confinement
High energy physics
Orbits
Electric fields
11 Citations (Scopus)

The role of the host defense system in the development of cerebral vasospasm: Analogies between atherosclerosis and subarachnoid hemorrhage

Yanamoto, H., Kataoka, H., Nakajo, Y. & Iihara, K., Dec 1 2012, In : European Neurology. 68, 6, p. 329-343 15 p.

Research output: Contribution to journalReview article

Intracranial Vasospasm
Subarachnoid Hemorrhage
Atherosclerosis
Cerebral Arteries
Constriction
9 Citations (Scopus)

The role of the OVOL1–OVOL2 axis in normal and diseased human skin

Tsuji, G., Ito, T., Chiba, T., Mitoma, C., Nakahara, T., Uchi, H. & Furue, M., Jun 2018, In : Journal of Dermatological Science. 90, 3, p. 227-231 5 p.

Research output: Contribution to journalReview article

Atopic Dermatitis
Skin Diseases
Skin
Genes
Tissue
4 Citations (Scopus)

The roles of heat shock proteins in host defense against bacterial infection

Yoshikai, Y., Jan 1 1998, In : Rinsho byori. The Japanese journal of clinical pathology. 46, 6, p. 564-573 10 p.

Research output: Contribution to journalReview article

Cytoprotection
Heat-Shock Proteins
Bacterial Infections
Inflammation
Bacteria
1 Citation (Scopus)

The roles of Hsp in inflammation

Yoshikai, Y., Jan 1 1994, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 39, 5, p. 837-845 9 p.

Research output: Contribution to journalReview article

Heat-Shock Proteins
Reactive Oxygen Species
Homeostasis
B-Lymphocytes
Cytokines
13 Citations (Scopus)
Kisspeptins
Perciformes
Cyprinidae
Fishes
Reproduction

The roles of OVOL1 and OVOL 2 in skin diseases

Tsuji, G., Jan 1 2017, In : Nishinihon Journal of Dermatology. 79, 6, p. 541-546 6 p.

Research output: Contribution to journalReview article

Skin Diseases
80 Citations (Scopus)

The roles of water molecules at the biointerface of medical polymers

Tanaka, M., Hayashi, T. & Morita, S., Jul 1 2013, In : Polymer Journal. 45, 7, p. 701-710 10 p.

Research output: Contribution to journalReview article

Polymers
Molecules
Water
Blood
Biocompatible Materials
2 Citations (Scopus)

The second therapeutic trial for children with hematological malignancies who relapsed after their first allogeneic SCT: Long-term outcomes

Nishikawa, T., Inagaki, J., Nagatoshi, Y., Fukano, R., nakashima, K., Ito, N., Sawa, D., Kawano, Y. & Okamura, J., Nov 1 2012, In : Pediatric Transplantation. 16, 7, p. 722-728 7 p.

Research output: Contribution to journalReview article

Hematologic Neoplasms
Recurrence
Therapeutics
Salvage Therapy
Mortality
65 Citations (Scopus)

The shift from "hard" to "soft" electronics

Tsutsui, T. & Fujita, K., Jul 4 2002, In : Advanced Materials. 14, 13-14, p. 949-952 4 p.

Research output: Contribution to journalReview article

Electronic equipment
Flexible displays
Flexible electronics
Silicon
Labels
13 Citations (Scopus)

The Significance of the PD-L1 Expression in Non–Small-Cell Lung Cancer: Trenchant Double Swords as Predictive and Prognostic Markers

Takada, K., Toyokawa, G., Shoji, F., Okamoto, T. & Maehara, Y., Mar 2018, In : Clinical Lung Cancer. 19, 2, p. 120-129 10 p.

Research output: Contribution to journalReview article

Non-Small Cell Lung Carcinoma
Cell Death
Ligands
CD274 Antigen
Immunotherapy
24 Citations (Scopus)

The silkworm-an attractive bioresource supplied by Japan

Banno, Y., Shimada, T., Kajiura, Z. & Sezutsu, H., Jul 20 2010, In : Experimental Animals. 59, 2, p. 139-146 8 p.

Research output: Contribution to journalReview article

Bombyx
Modernization
silkworms
Japan
Experiments

The sophisticated mechanisms of the mRNA splicing on the endoplasmic reticulum

Yanagitani, K. & Kohno, K., Dec 1 2012, In : Seikagaku. 84, 4, p. 290-294 5 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

The structure of hypernuclei and hyperon mixing in neutron-star matter

Hiyama, E., Yamamoto, Y. & Sagawa, H., Jul 27 2016, In : Physica Scripta. 91, 9, 093001.

Research output: Contribution to journalReview article

hypernuclei
Neutron Stars
neutron stars
Shell
Nucleus
4 Citations (Scopus)

The subgenus Pentapedilum Kieffer (Diptera: Chironomidae) in the Yaeyama Islands, the Ryukyus, Japan

Yamamoto, N., Hirowatari, T. & Yamamoto, M., Feb 13 2012, In : Zootaxa. 3191, p. 33-40 8 p.

Research output: Contribution to journalReview article

Polypedilum
Chironomidae
Sasa
Japan
membrane

The T-cell antigen receptor and T-cell antigen recognition

Yanagi, Y., Feb 1988, In : Seikagaku. The Journal of Japanese Biochemical Society. 60, 2, p. 75-88 14 p.

Research output: Contribution to journalReview article

Viral Tumor Antigens
T-Cell Antigen Receptor
T-Lymphocytes
25 Citations (Scopus)

The Tokyo Twin Cohort Project: Overview and initial findings

Ando, J., Nonaka, K., Ozaki, K., Sato, N., Fujisawa, K. K., Suzuki, K., Yamagata, S., Takahashi, Y., Nakajima, R., Kato, N. & Ooki, S., Dec 1 2006, In : Twin Research and Human Genetics. 9, 6, p. 817-826 10 p.

Research output: Contribution to journalReview article

Tokyo
Registries
Multiple Birth Offspring
Placentation
Selection Bias
80 Citations (Scopus)

The transcription factor Pokemon: A new key player in cancer pathogenesis

Maeda, T., Hobbs, R. M. & Pandolfi, P. P., Oct 1 2005, In : Cancer Research. 65, 19, p. 8575-8578 4 p.

Research output: Contribution to journalReview article

Transcription Factors
Neoplasms
Learning
Therapeutics

The treatment of rheumatoid arthritis with NF-kappaB inhibitors

Jimi, E. & Nakamura, I., Jan 1 2005, In : Nippon rinsho. Japanese journal of clinical medicine. 63, 9, p. 1627-1632 6 p.

Research output: Contribution to journalReview article

Rheumatoid Arthritis
Synovial Membrane
Arthritis
Joints
Lymphocytes
19 Citations (Scopus)

The unique electrical properties in an extracellular fluid of the mammalian cochlea; their functional roles, homeostatic processes, and pathological significance

Nin, F., Yoshida, T., Sawamura, S., Ogata, G., Ota, T., Higuchi, T., Murakami, S., Doi, K., Kurachi, Y. & Hibino, H., Oct 1 2016, In : Pflugers Archiv European Journal of Physiology. 468, 10, p. 1637-1649 13 p.

Research output: Contribution to journalReview article

Endolymph
Cochlea
Extracellular Fluid
Pathologic Processes
Electric properties
237 Citations (Scopus)

The use of aurophilic and other metal-metal interactions as crystal engineering design elements to increase structural dimensionality

Katz, M. J., Sakai, K. & Leznoff, D. B., Sep 9 2008, In : Chemical Society Reviews. 37, 9, p. 1884-1895 12 p.

Research output: Contribution to journalReview article

Crystal engineering
Metals
Gold
Physical properties
Supramolecular chemistry
Osteoporosis
Pharmacokinetics
Pharmaceutical Preparations
Population
Bone Remodeling
1 Citation (Scopus)

The US health care and the reform

Babazono, A., Tsuda, T. & Mino, Y., Jan 1 1996, In : Japanese Journal of Hygiene. 51, 3, p. 666-676 11 p.

Research output: Contribution to journalReview article

Health Care Reform
Delivery of Health Care
Managed Competition
Health Care Sector
Quality of Health Care
10 Citations (Scopus)

The value of home blood pressure monitoring

shimizu, M., Shibasaki, S. & Kario, K., Oct 1 2006, In : Current Hypertension Reports. 8, 5, p. 363-367 5 p.

Research output: Contribution to journalReview article

Ambulatory Blood Pressure Monitoring
Masked Hypertension
White Coat Hypertension
Blood Pressure
Equipment and Supplies
13 Citations (Scopus)

The wild Oryza collection in National BioResource Project (NBRP) of Japan: History, biodiversity and utility

Nonomura, K. I., Morishima, H., Miyabayashi, T., Yamaki, S., Eiguchi, M., Kubo, T. & Kurata, N., Dec 1 2010, In : Breeding Science. 60, 5, p. 502-508 7 p.

Research output: Contribution to journalReview article

Oryza
Biodiversity
Japan
History
biodiversity
115 Citations (Scopus)

The Wnt/β-catenin signaling pathway as a target in drug discovery

Takahashi-Yanaga, F. & Sasaguri, T., Sep 13 2007, In : Journal of Pharmacological Sciences. 104, 4, p. 293-302 10 p.

Research output: Contribution to journalReview article

Catenins
Wnt Signaling Pathway
Drug Discovery
Wnt Proteins
Pharmaceutical Preparations
62 Citations (Scopus)

Thioredoxin and ventricular remodeling

Ago, T. & Sadoshima, J., Nov 1 2006, In : Journal of Molecular and Cellular Cardiology. 41, 5, p. 762-773 12 p.

Research output: Contribution to journalReview article

Thioredoxins
Ventricular Remodeling
Reactive Oxygen Species
Antioxidants
Post Translational Protein Processing
236 Citations (Scopus)

Third-generation organic electroluminescence materials

Adachi, C., Jun 2014, In : Japanese Journal of Applied Physics. 53, 6, 060101.

Research output: Contribution to journalReview article

Electroluminescence
electroluminescence
light emitting diodes
Organic light emitting diodes (OLED)
fluorescence
23 Citations (Scopus)

Three-dimensional strain mapping using in situ X-ray synchrotron microtomography

Toda, H., Maire, E., Aoki, Y. & Kobayashi, M., Oct 1 2011, In : Journal of Strain Analysis for Engineering Design. 46, 7, p. 549-561 13 p.

Research output: Contribution to journalReview article

Microtomography
Synchrotrons
X rays
Three-dimensional
Image resolution

Threshold of Application of Antidepressant Drugs for Treatment of Depressive Disorder

Kuroki, T. & Tanaka, T., Jan 1 2015, In : Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. 117, 4, p. 269-276 8 p.

Research output: Contribution to journalReview article

Depressive Disorder
Antidepressive Agents
Depression
Therapeutics
Guidelines
57 Citations (Scopus)

Th subset balance in lupus nephritis

Miyake, K., Akahoshi, M. & Nakashima, H., Nov 24 2011, In : Journal of Biomedicine and Biotechnology. 2011, 980286.

Research output: Contribution to journalReview article

Lupus Nephritis
Cytokines
T-cells
Lymphocytes
Interleukin-17
33 Citations (Scopus)

Thymic generation and selection of CD25+CD4+ regulatory T cells: Implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance

Sakaguchi, S., Hori, S., Fukui, Y., Sasazuki, T., Sakaguchi, N., Takahashi, T. & Bach, Dec 1 2003, In : Novartis Foundation symposium. 252, p. 6-23 18 p.

Research output: Contribution to journalReview article

Self Tolerance
Regulatory T-Lymphocytes
Thymus Gland
T-Lymphocytes
Ligands
24 Citations (Scopus)

Time to be versatile: Regulation of the replication timing program in budding yeast

Yoshida, K., Poveda, A. & Pasero, P., Nov 29 2013, In : Journal of Molecular Biology. 425, 23, p. 4696-4705 10 p.

Research output: Contribution to journalReview article

Saccharomycetales
Replication Origin
S Phase
Peptide Initiation Factors
Licensure
6 Citations (Scopus)

Tissue culture on a chip: Developmental biology applications of self-organized capillary networks in microfluidic devices

Miura, T. & Yokokawa, R., Aug 1 2016, In : Development Growth and Differentiation. 58, 6, p. 505-515 11 p.

Research output: Contribution to journalReview article

Lab-On-A-Chip Devices
Developmental Biology
Organ Culture Techniques
Microfluidics
Microcirculation

Tissue-specific distribution of genistein, daidzein and bisphenol A in male Sprague-Dawley rats after intragastric administration

Yasuda, S., Wu, P. S., Okabe, M., Tachibana, H. & Yamada, K., May 1 2005, In : Food Science and Technology Research. 11, 2, p. 187-193 7 p.

Research output: Contribution to journalReview article

intragastric administration
bisphenol A
daidzein
Genistein
genistein

Topical corticosteroids: How to use in clinical practice

Furue, M., Jul 27 2009, In : Japanese Journal of Allergology. 58, 5, p. 491-497 7 p.

Research output: Contribution to journalReview article

Topical Administration
Preschool Children
Atopic Dermatitis
Adrenal Cortex Hormones

Topical steroids and tacrolimus for the treatment of atopic dermatitis

Furue, M., Oct 2006, In : Fukuoka igaku zasshi = Hukuoka acta medica. 97, 10, p. 285-292 8 p.

Research output: Contribution to journalReview article

Topical Administration
Evidence-Based Medicine
Tacrolimus
Patient Education
Atopic Dermatitis
1 Citation (Scopus)

Topical tacrolimus as treatment of atopic dermatitis

Furue, M. & Takeuchi, S., Dec 1 2009, In : Clinical, Cosmetic and Investigational Dermatology. 2, p. 161-166 6 p.

Research output: Contribution to journalReview article

Tacrolimus
Atopic Dermatitis
Eczematous Skin Diseases
Steroids
Therapeutics
3 Citations (Scopus)

Topical tacrolimus in the management of atopic dermatitis in Japan

Furue, M., Uchi, H., Moroi, Y., Ogawa, S., Nakahara, T. & Urabe, K., Mar 1 2006, In : Dermatologic Therapy. 19, 2, p. 118-126 9 p.

Research output: Contribution to journalReview article

Tacrolimus
Atopic Dermatitis
Japan
Steroids
Eczematous Skin Diseases
51 Citations (Scopus)

Topographic mapping--the olfactory system.

Imai, T., Sakano, H. & Vosshall, L. B., Aug 1 2010, In : Cold Spring Harbor Perspectives in Biology. 2, 8

Research output: Contribution to journalReview article

Olfactory Bulb
Insects
Mammals
Odorant Receptors
Neurons
30 Citations (Scopus)

Total pancreatectomy for intraductal papillary-mucinous tumor of the pancreas: Reappraisal of total pancreatectomy

Yamaguchi, K., Konomi, H., Kobayashi, K., Ogura, Y., Sonoda, Y., Kawamoto, M., Nakano, K. & Tanaka, M., Sep 1 2005, In : Hepato-gastroenterology. 52, 65, p. 1585-1590 6 p.

Research output: Contribution to journalReview article

Pancreatectomy
Pancreas
Neoplasms
Liver Abscess
Pylorus

Total parenteral nutrition in pediatric stem cell transplantation

Kato, K., Matsuyama, T., Murahashi, O., Umeda, R. & Sugito, T., Jan 1 2001, In : Nippon rinsho. Japanese journal of clinical medicine. 59 Suppl 5, p. 815-818 4 p.

Research output: Contribution to journalReview article

Central Venous Catheterization
Nutrition Assessment
Total Parenteral Nutrition
Hematopoietic Stem Cell Transplantation
Stem Cell Transplantation
54 Citations (Scopus)

Total synthesis and chemical biology of the sarcodictyins

Nicolaou, K. C., Pfefferkorn, J., Xu, J., Winssinger, N., Ohshima, T., Kim, S., Hosokawa, S., Vourloumis, D., Van Delft, F. & Li, T., Sep 1999, In : Chemical and Pharmaceutical Bulletin. 47, 9, p. 1199-1213 15 p.

Research output: Contribution to journalReview article

Diterpenes
Structure-Activity Relationship
Tubulin
Cytotoxicity
Paclitaxel
37 Citations (Scopus)

To wake up cancer stem cells, or to let them sleep, that is the question

Takeishi, S. & Nakayama, K. I., Jul 1 2016, In : Cancer Science. 107, 7, p. 875-881 7 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Sleep
Cell Cycle
Stem Cell Niche
Therapeutics