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  • Hiroyuki Tsutsui
2013

Suppression of ventricular fibrillation by electrical modification of the Purkinje system in hypertrophic cardiomyopathy

Yokoshiki, H., Mitsuyama, H., Watanabe, M., Mizukami, K. & Tsutsui, H., Jan 1 2013, In : Heart and Vessels. 29, 5, p. 709-717 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Interrelation between myocardial oxidative metabolism and diastolic function in patients undergoing surgical ventricular reconstruction

Chiba, S., Naya, M., Iwano, H., Yoshinaga, K., Katoh, C., Manabe, O., Yamada, S., Wakasa, S., Kubota, S., Matsui, Y., Tamaki, N. & Tsutsui, H., Feb 1 2013, In : European Journal of Nuclear Medicine and Molecular Imaging. 40, 3, p. 349-355 7 p.

Research output: Contribution to journalArticle

2016

Bedside teaching serelaxin

Tsutsui, H., Jul 1 2016, In : Respiration and Circulation. 64, 7, p. 725-730 6 p.

Research output: Contribution to journalArticle

2012

Decreased glomerular filtration rate is a significant and independent risk for in-hospital mortality in Japanese patients with acute myocardial infarction: Report from the Hokkaido acute myocardial infarction registry

Satoh, H., Ishimori, N., Sakakibara, M., Yamada, S., Kawashima, N., Urasawa, K., Fujii, S. & Tsutsui, H., Apr 1 2012, In : Hypertension Research. 35, 4, p. 463-469 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2013

Exercise intolerance in chronic heart failure - Skeletal muscle dysfunction and potential therapies

Okita, K., Kinugawa, S. & Tsutsui, H., Feb 4 2013, In : Circulation Journal. 77, 2, p. 293-300 8 p.

Research output: Contribution to journalReview article

61 Citations (Scopus)
2012

Conduction and refractory disorders in the diabetic atrium

Watanabe, M., Yokoshiki, H., Mitsuyama, H., Mizukami, K., Ono, T. & Tsutsui, H., Jul 1 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 303, 1, p. H86-H95

Research output: Contribution to journalArticle

41 Citations (Scopus)
2013

Unique preferential conduction within the isolated septal substrate in a patient with ventricular tachycardia complicated with non-ischemic dilated cardiomyopathy

Watanabe, M., Yokoshiki, H., Mitsuyama, H., Mizukami, K. & Tsutsui, H., Nov 1 2013, In : Journal of Electrocardiology. 46, 6, p. 682-685 4 p.

Research output: Contribution to journalArticle

[Multidisciplinary management for heart failure --prevention, diagnosis and updated treatment].

Yokoshiki, H., Tsutsui, H., Goto, D., Kinugawa, S. & Ooka, T., Jan 1 2013, In : Unknown Journal. 88, 1, p. 11-14 4 p.

Research output: Contribution to journalArticle

2012

Cardiac (18)F-FDG PET/CT with heparin detects infective vegetation in a patient with mechanical valve replacement.

Klaipetch, A., Manabe, O., Oyama-Manabe, N., Chiba, S., Naya, M., Yamada, S., Hirata, K., Tsutsui, H. & Tamaki, N., Jan 1 2012, In : Clinical nuclear medicine. 37, 12, p. 1184-1185 2 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Blood flow restriction exercise in sprinters and endurance runners

Takada, S., Okita, K., Suga, T., Omokawa, M., Morita, N., Horiuchi, M., Kadoguchi, T., Takahashi, M., Hirabayashi, K., Yokota, T., Kinugawa, S. & Tsutsui, H., Mar 1 2012, In : Medicine and Science in Sports and Exercise. 44, 3, p. 413-419 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2011

Syndecan-4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cell proliferation and vascular progenitor cell mobilization

Ikesue, M., Matsui, Y., Ohta, D., Danzaki, K., Ito, K., Kanayama, M., Kurotaki, D., Morimoto, J., Kojima, T., Tsutsui, H. & Uede, T., May 1 2011, In : Arteriosclerosis, thrombosis, and vascular biology. 31, 5, p. 1066-1074 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2012
2016

Relationship between uric acid and coronary artery disease

Sakakibara, M. & Tsutsui, H., Jun 20 2016, In : Nippon rinsho. Japanese journal of clinical medicine. 74 Pt 1, p. 165-171 7 p.

Research output: Contribution to journalArticle

2011

Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction

Matsui, Y., Ikesue, M., Danzaki, K., Morimoto, J., Sato, M., Tanaka, S., Kojima, T., Tsutsui, H. & Uede, T., May 27 2011, In : Circulation research. 108, 11, p. 1328-1339 12 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
2015

Assessment of coronary flow reserve by dynamic single-photon emission computed tomography

Naya, M. & Tsutsui, H., Jan 1 2015, In : Circulation Journal. 79, 3, p. 515-516 2 p.

Research output: Contribution to journalEditorial

2013
2019

Unexpected, but reasonable association between anderson-fabry disease and coronary vasospasm

Matoba, T., Nakano, Y. & Tsutsui, H., Feb 2019, In : Circulation Journal. 83, 2, p. 283-284 2 p.

Research output: Contribution to journalArticle

2015

Small-conductance Ca2+-activated K+ current is upregulated via the phosphorylation of CaMKII in cardiac hypertrophy from spontaneously hypertensive rats

Mizukami, K., Yokoshiki, H., Mitsuyama, H., Watanabe, M., Tenma, T., Takada, S. & Tsutsui, H., Sep 18 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 6, p. H1066-H1074

Research output: Contribution to journalArticle

10 Citations (Scopus)

Persistent depression is a significant risk factor for the development of arteriosclerosis in middle-aged Japanese male subjects

Satoh, H., Fujii, S. & Tsutsui, H., Jan 8 2015, In : Hypertension Research. 38, 1, p. 84-88 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Relation Between Dabigatran Concentration, as Assessed Using the Direct Thrombin Inhibitor Assay, and Activated Clotting Time/Activated Partial Thromboplastin Time in Patients With Atrial Fibrillation

Okubo, K., Kuwahara, T., Takagi, K., Takigawa, M., Nakajima, J., Watari, Y., Nakashima, E., Yamao, K., Fujino, T., Tsutsui, H. & Takahashi, A., Jun 15 2015, In : American Journal of Cardiology. 115, 12, p. 1696-1699 4 p., 21051.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2014

TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: Implications for inflammation in atherosclerosis

Ito, S., Iwaki, S., Kondo, R., Satoh, M., Iwabuchi, K., Ohkawa, R., Mishima, Y., Yatomi, Y., Furumoto, T., Tsutsui, H. & Fujii, S., Jan 1 2014, In : Coronary Artery Disease. 25, 4, p. 311-320 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2015
16 Citations (Scopus)
2019

Prior exposure to placental ischemia causes increased salt sensitivity of blood pressure via vasopressin production and secretion in postpartum rats

Matsuura, T., Shinohara, K., Iyonaga, T., Hirooka, Y. & Tsutsui, H., Aug 1 2019, In : Journal of hypertension. 37, 8, p. 1657-1667 11 p.

Research output: Contribution to journalArticle

2014

Assessment of quality of life during long-term treatment of tolvaptan in refractory heart failure: Design and rationale of the AQUA-TLV study

Imamura, T., Kinugawa, K., Ohtani, T., Sakata, Y., Higo, T., Kinugawa, S., Tsutsui, H., Sunagawa, K. & Komuro, I., 2014, In : International heart journal. 55, 3, p. 264-267 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2013

Acute hemodynamic effects of adaptive servo-ventilation in patients with heart failure

Yamada, S., Sakakibara, M., Yokota, T., Kamiya, K., Asakawa, N., Iwano, H., Yamada, S., Oba, K. & Tsutsui, H., May 1 2013, In : Circulation Journal. 77, 5, p. 1214-1220 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2012

Clinical efficacy of cardiac resynchronization therapy with an implantable defibrillator in a Japanese population - Results of the MIRACLE-ICD outcome measured in Japanese indication (MOMIJI) study -

Momomura, S. I., Tsutsui, H., Sugawara, Y., Ito, M., Mitsuhashi, T., Fukamizu, S., Noro, M., Matsumoto, N., Tejim, T. & Sugi, K., Aug 2 2012, In : Circulation Journal. 76, 8, p. 1911-1919 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Limitation of echocardiographic indexes for the accurate estimation of left ventricular relaxation and filling pressure: Interim results of SMAP, a multicenter study in Japan

Yamada, S., Iwano, H., Tsutsui, H., Ohte, N., Wakami, K., Seo, Y., Ishizu, T., Yamada, H., Kusunose, K. & Mikami, T., Feb 1 2012, In : Choonpa Igaku. 39, 4, p. 449-456 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Association of peripartum troponin i levels with left ventricular relaxation in women with hypertensive disorders of pregnancy

Umazume, T., Yamada, S., Yamada, T., Ishikawa, S., Furuta, I., Iwano, H., Murai, D., Hayashi, T., Okada, K., Morikawa, M., Tsutsui, H. & Minakami, H., Jan 1 2018, In : Open Heart. 5, 2, e000829.

Research output: Contribution to journalArticle

2012

Sleep-disordered breathing is an independent risk factor of aborted sudden cardiac arrest in patients with coronary artery spasm

Sakakibara, M., Yamada, S., Kamiya, K., Yokota, T., Oba, K. & Tsutsui, H., Sep 4 2012, In : Circulation Journal. 76, 9, p. 2204-2210 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

Report of the American Heart Association (AHA) scientific sessions 2013, Dallas

Ishimori, N., Kinugawa, S., Yamada, S., Yokoshiki, H., Mitsuyama, H. & Tsutsui, H., Jan 1 2014, In : Circulation Journal. 78, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2011

Sex differences with respect to clinical characteristics, treatment, and long-term outcomes in patients with heart failure

Tsuchihashi-Makaya, M., Hamaguchi, S., Kinugawa, S., Goto, K., Goto, D., Furumoto, T., Yamada, S., Yokoshiki, H., Takeshita, A. & Tsutsui, H., Aug 4 2011, In : International Journal of Cardiology. 150, 3, p. 338-339 2 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2014

Coronary flow reserve estimated by positron emission tomography to diagnose significant coronary artery disease and predict cardiac events

Naya, M., Tamaki, N. & Tsutsui, H., Dec 19 2014, In : Circulation Journal. 79, 1, p. 15-23 9 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)
2017

Usefulness of the Continuous-Wave Doppler-Derived Pulmonary Arterial–Right Ventricular Pressure Gradient Just before Atrial Contraction for the Estimation of Pulmonary Arterial Diastolic and Wedge Pressures

Murayama, M., Mikami, T., Kaga, S., Okada, K., Hioka, T., Masauzi, N., Nakabachi, M., Nishino, H., Yokoyama, S., Nishida, M., Iwano, H., Sakakibara, M., Yamada, S. & Tsutsui, H., May 1 2017, In : Ultrasound in Medicine and Biology. 43, 5, p. 958-966 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2011

Single-slice epicardial fat area measurement: Do we need to measure the total epicardial fat volume?

Oyama, N., Goto, D., Ito, Y. M., Ishimori, N., Mimura, R., Furumoto, T., Kato, F., Tsutsui, H., Tamaki, N., Terae, S. & Shirato, H., Feb 1 2011, In : Japanese Journal of Radiology. 29, 2, p. 104-109 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2016

Characteristics of idiopathic ventricular tachycardia originating above the pulmonary valve

Yokoshiki, H., Mizukami, K., Mitsuyama, H., Watanabe, M., Tenma, T. & Tsutsui, H., Apr 1 2016, In : Heart and Vessels. 31, 4, p. 599-607 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2013

Clinical characteristics and outcomes of dilated phase of hypertrophic cardiomyopathy: Report from the registry data in Japan

Goto, D., Kinugawa, S., Hamaguchi, S., Sakakibara, M., Tsuchihashi-Makaya, M., Yokota, T., Yamada, S., Yokoshiki, H. & Tsutsui, H., Jan 1 2013, In : Journal of Cardiology. 61, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Management and two-year long-term clinical outcome of acute coronary syndrome in Japan - Prevention of atherothrombotic incidents following ischemic coronary attack (PACIFIC) registry -

Daida, H., Miyauchi, K., Ogawa, H., Yokoi, H., Matsumoto, M., Kitakaze, M., Kimura, T., Matsubara, T., Ikari, Y., Kimura, K., Tsukahara, K., Origasa, H., Morino, Y., Tsutsui, H., Kobayashi, M. & Isshiki, T., Apr 3 2013, In : Circulation Journal. 77, 4, p. 934-943 10 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)
2019

Nationwide survey of multidisciplinary care and cardiac rehabilitation for patients with heart failure in Japan ― An analysis of the AMED-CHF study ―

Kamiya, K., Yamamoto, T., Tsuchihashi-Makaya, M., Ikegame, T., Takahashi, T., Sato, Y., Kotooka, N., Saito, Y., Tsutsui, H., Miyata, H. & Isobe, M., Jan 1 2019, In : Circulation Journal. 83, 7, p. 1546-1552 7 p.

Research output: Contribution to journalArticle

Open Access
2011

Incremental diagnostic value of regional myocardial blood flow quantification over relative perfusion imaging with generator-produced rubidium-82 PET

Yoshinaga, K., Katoh, C., Manabe, O., Klein, R., Naya, M., Sakakibara, M., Yamada, S., de Kemp, R. A., Tsutsui, H. & Tamaki, N., Oct 31 2011, In : Circulation Journal. 75, 11, p. 2628-2634 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2013

Efficacy and safety of a 60-week treatment with candesartan in Japanese patients with mild to moderate chronic heart failure

Matsuzaki, M., Yamamoto, K., Yano, M., Nakamura, K., Miyata, Y., Sugiura, K., Nakata, E. & Tsutsui, H., Apr 1 2013, In : Journal of Cardiology. 61, 4, p. 267-274 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

A statement on the appropriate administration of tafamidis in patients with transthyretin cardiac amyloidosis

Endo, J., Sano, M., Izumiya, Y., Tsujita, K., Nakamura, K., Tahara, N., Kuwahara, K., Inomata, T., Ueda, M., Sekijima, Y., Ando, Y., Tsutsui, H., Isobe, M. & Fukuda, K., Jan 1 2019, In : Circulation Journal. 84, 1, p. 15-17 3 p.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)
2013

Home telemonitoring study for Japanese patients with heart failure (HOMES-HF): Protocol for a multicentre randomised controlled trial

Kotooka, N., Asaka, M., Sato, Y., Kinugasa, Y., Nochioka, K., Mizuno, A., Nagatomo, D., Mine, D., Yamada, Y., Eguchi, K., Hanaoka, H., Inomata, T., Fukumoto, Y., Yamamoto, K., Tsutsui, H., Masuyama, T., Kitakaze, M., Inoue, T., Shimokawa, H., Momomura, S. I. & 2 others, Seino, Y. & Node, K., Jun 13 2013, In : BMJ open. 3, 6, e002972.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2012

Activation of natural killer T cells ameliorates postinfarct cardiac remodeling and failure in mice

Sobirin, M. A., Kinugawa, S., Takahashi, M., Fukushima, A., Homma, T., Ono, T., Hirabayashi, K., Suga, T., Azalia, P., Takada, S., Taniguchi, M., Nakayama, T., Ishimori, N., Iwabuchi, K. & Tsutsui, H., Sep 1 2012, In : Circulation research. 111, 8, p. 1037-1047 11 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2013

Minimal dose for effective clinical outcome and predictive factors for responsiveness to carvedilol: Japanese chronic heart failure (J-CHF) study

Okamoto, H., Hori, M., Matsuzaki, M., Tsutsui, H., Yamazaki, T., Nagai, R., Yoshikawa, T., Fujio, Y., Nonen, S., Azuma, J., Izumi, T., Ohashi, Y. & Kitabatake, A., Apr 5 2013, In : International Journal of Cardiology. 164, 2, p. 238-244 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2018

Small-conductance Ca2+-activated K+ channel activation deteriorates hypoxic ventricular arrhythmias via CaMKII in cardiac hypertrophy

Tenma, T., Mitsuyama, H., Watanabe, M., Kakutani, N., Otsuka, Y., Mizukami, K., Kamada, R., Takahashi, M., Takada, S., Sabe, H., Tsutsui, H. & Yokoshiki, H., Aug 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 315, 2, p. H262-H272

Research output: Contribution to journalArticle

2 Citations (Scopus)

Diagnostic value of quantitative coronary flow reserve and myocardial blood flow estimated by dynamic 320 MDCT scanning in patients with obstructive coronary artery disease

Obara, M., Naya, M., Oyama-Manabe, N., Aikawa, T., Tomiyama, Y., Sasaki, T., Kikuchi, Y., Manabe, O., Katoh, C., Tamaki, N. & Tsutsui, H., Jul 1 2018, In : Medicine (United States). 97, 27, e11354.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

Overestimation by echocardiography of the peak systolic pressure gradient between the right ventricle and right atrium due to tricuspid regurgitation and the usefulness of the early diastolic transpulmonary valve pressure gradient for estimating pulmonary artery pressure

Hioka, T., Kaga, S., Mikami, T., Okada, K., Murayama, M., Masauzi, N., Nakabachi, M., Nishino, H., Yokoyama, S., Nishida, M., Iwano, H., Sakakibara, M., Yamada, S. & Tsutsui, H., Jul 1 2017, In : Heart and Vessels. 32, 7, p. 833-842 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2019

Left atrial involvement of cardiac sarcoidosis manifesting as left atrial re-entrant tachycardia

Enzan, N., Ohtani, K., Nagaoka, K., Sakamoto, I. & Tsutsui, H., Aug 1 2019, In : European heart journal cardiovascular Imaging. 20, 8, 1 p., jez051.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Efficacy and safety of ivabradine in Japanese patients with chronic heart failure ― J-SHIFT study ―

behalf of the J-SHIFT Study Investigators, Jan 1 2019, In : Circulation Journal. 83, 10, p. 2049-2060 12 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2011

Long-Term Survival in Implantable Cardioverter-Defibrillators(ICD) Leads Inserted by the Extrathoracic Introduction Technique

Watanabe, M., Yokoshiki, H., Mitsuyama, H., Matsui, Y. & Tsutsui, H., Jan 1 2011, In : journal of arrhythmia. 27

Research output: Contribution to journalArticle