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2014

The actual state and problems in neurology training at hospital

Fukutake, T., Hashimoto, Y., Taniwaki, T., Toyoshima, I., Amano, T., Aoki, M., Yoshii, F., Inuzuka, T. & Kira, J-I., Jan 1 2014, In : Clinical Neurology. 54, 4, p. 341-348 8 p.

Research output: Contribution to journalArticle

Neurology
Teaching
Certification
Teaching Hospitals
Education
2013
4 Citations (Scopus)

Month of birth in multiple sclerosis with and without longitudinally extensive spinal cord lesions: A study of a Japanese national survey

Araki, Y., Kinoshita, M., Motoyama, R., Matsushita, T., Nakagawa, M., Kira, J. I. & Tanaka, M., Jul 15 2013, In : Journal of the Neurological Sciences. 330, 1-2, p. 67-70 4 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Spinal Cord
Parturition
Population
Surveys and Questionnaires
2015

Neuropathology of multiple sclerosis

Masaki, K. & Kira, J. I., Sep 1 2015, In : Nihon rinsho. Japanese journal of clinical medicine. 73, p. 141-149 9 p.

Research output: Contribution to journalArticle

Acute Disease
Meningitis
Multiple Sclerosis
Disease Progression
Chronic Disease

Background and trigger factors for neuroimmunological diseases

Kira, J. I., Sep 1 2015, In : Nihon rinsho. Japanese journal of clinical medicine. 73, p. 13-22 10 p.

Research output: Contribution to journalArticle

Autoimmune Diseases of the Nervous System
Feeding Behavior
Genetic Predisposition to Disease
HLA Antigens
Autoimmunity
2013
7 Citations (Scopus)
Neuromyelitis Optica
Multiple Sclerosis
Aquaporin 4
Sanitation
Age of Onset
7 Citations (Scopus)

A guide to facilitate the early treatment of patients with idiopathic demyelinating disease (multiple sclerosis and neuromyelitis optica)

Carroll, W. M., Saida, T., Kim, H. J., Kira, J., Kermode, A. G., Tsai, C. P., Fujihara, K., Kusunoki, S., Tanaka, M., Kim, K. K. & Bates, D., Sep 2013, In : Multiple Sclerosis Journal. 19, 10, p. 1371-1380 10 p.

Research output: Contribution to journalReview article

Neuromyelitis Optica
Demyelinating Diseases
Multiple Sclerosis
Therapeutics
Neurology
2014
3 Citations (Scopus)

Japanese guidelines for fingolimod in multiple sclerosis: Putting into practice

Matsui, M., Shimizu, Y., Doi, H., Tomioka, R., Nakashima, I., Niino, M. & Kira, J-I., Jan 1 2014, In : Clinical and Experimental Neuroimmunology. 5, 1, p. 34-48 15 p.

Research output: Contribution to journalReview article

Multiple Sclerosis
Guidelines
Lysosphingolipid Receptors
Aquaporin 4
Neuromyelitis Optica
2011

Erratum: Recurrent Hopkin's syndrome: A case report and review of the literature (Journal of the Neurological Sciences (2010) 297 (89-91))

Pavone, P., Longo, M. R., Scalia, F., Polosa, R., Kira, J. I. & Falsaperla, R., Apr 15 2011, In : Journal of the Neurological Sciences. 303, 1-2, 1 p.

Research output: Contribution to journalComment/debate

2016
3 Citations (Scopus)
MELAS Syndrome
Rhabdomyolysis
Status Epilepticus
Stroke
Occipital Lobe
2014
Multiple Sclerosis
Japan
Research
2018

Oral phase dysphagia in facial onset sensory and motor neuronopathy

Watanabe, M., Shiraishi, W., Yamasaki, R., Isobe, N., Sawatsubashi, M., Yasumatsu, R., Nakagawa, T. & Kira, J. I., Jun 2018, In : Brain and Behavior. 8, 6, e00999.

Research output: Contribution to journalArticle

Deglutition Disorders
Deglutition
Pharynx
Aspiration Pneumonia
Gastrostomy
Vesicular Glutamate Transport Protein 2
STAT3 Transcription Factor
Transcriptional Activation
Glutamic Acid
Spinal Cord
2017

Safety and effectiveness of interferon β-1a intramuscular therapy: results of the postmarketing drug surveillance in Japan

Makioka, H., Nakaya, F., Ling, Y., Torii, S., Saida, T. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 10, p. 553-561 9 p.

Research output: Contribution to journalArticle

Postmarketing Product Surveillance
Interferons
Japan
Safety
Recurrence
2018

The neuropathological study of myelin oligodendrocyte glycoprotein in the temporal lobe of schizophrenia patients

Marui, T., Torii, Y., Iritani, S., Sekiguchi, H., Habuchi, C., Fujishiro, H., Oshima, K., Niizato, K., Hayashida, S., Masaki, K., Kira, J. & Ozaki, N., Aug 1 2018, In : Acta Neuropsychiatrica. 30, 4, p. 232-240 9 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Temporal Lobe
Schizophrenia
Oligodendroglia
Brain
2016

Minocycline-induced human herpesvirus 6 encephalomyelitis with drastically disseminated contrast-enhanced lesions

Shinoda, K., Iwata, T., Nakamura, Y., Masaki, K., Matsushita, T., Yamasaki, R. & Kira, J. I., Dec 1 2016, In : European Journal of Neurology. 23, 12, p. e76-e77

Research output: Contribution to journalLetter

Drug Hypersensitivity Syndrome
Human Herpesvirus 6
Encephalomyelitis
Minocycline
Magnetic Resonance Imaging

Recurrent cerebellitis associated with primary Sjögren's syndrome

Shinoda, K., Murai, H., Akutagawa, N., Ochi, H. & Kira, J. I., May 1 2016, In : Clinical and Experimental Neuroimmunology. 7, 2, p. 183-184 2 p.

Research output: Contribution to journalLetter

Sjogren's Syndrome
2011
8 Citations (Scopus)

Astrocytopathy in neuromyelitis optica, multiple sclerosis and Baló's disease

Matsushita, T., Masaki, K., Suzuki, S., Matsuoka, T., Yonekawa, T., Wu, X. M., Tabira, T., Iwaki, T. & Kira, J. I., Dec 1 2011, In : Clinical Neurology. 51, 11, p. 898-900 3 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Demyelinating Diseases
Aquaporin 4
Connexin 43
Multiple Sclerosis
2014
Neurosciences
Allergy and Immunology
Myelitis
Multiple Sclerosis
Hyperalgesia
2012
20 Citations (Scopus)
Aquaporin 4
Neuroimaging
Central Nervous System
Antibodies
Spinal Cord
2015
11 Citations (Scopus)

Analysis of cerebral lobar microbleeds and a decreased cerebral blood flow in a memory clinic setting

Doi, H., Inamizu, S., Saito, B. Y., Murai, H., Araki, T. & Kira, J. I., Jan 1 2015, In : Internal Medicine. 54, 9, p. 1027-1033 7 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Occipital Lobe
Parietal Lobe
Brain
Frontal Lobe
2019

Long-term use of interferon-β in multiple sclerosis increases Vδ1-Vδ2-Vγ9- γδ T cells that are associated with a better outcome

Maimaitijiang, G., Watanabe, M., Shinoda, K., Isobe, N., Nakamura, Y., Masaki, K., Matsushita, T., Yoshikai, Y. & Kira, J. I., Sep 13 2019, In : Journal of neuroinflammation. 16, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Interferons
Multiple Sclerosis
T-Lymphocytes
B-Lymphocytes
T-Lymphocyte Subsets
2019
Mitochondrial DNA
Mitochondria
Pharmaceutical Preparations
2011
76 Citations (Scopus)

Characteristics of myasthenia gravis according to onset-age: Japanese nationwide survey

Murai, H., Yamashita, N., Watanabe, M., Nomura, Y., Motomura, M., Yoshikawa, H., Nakamura, Y., Kawaguchi, N., Onodera, H., Araga, S., Isobe, N., Nagai, M. & Kira, J. I., Jun 15 2011, In : Journal of the Neurological Sciences. 305, 1-2, p. 97-102 6 p.

Research output: Contribution to journalArticle

Myasthenia Gravis
Age of Onset
Japan
Thymoma
Cholinergic Receptors
2013
5 Citations (Scopus)
Tropical Spastic Paraparesis
Spinal Cord Diseases
Thiamine
Viruses
Beriberi
2 Citations (Scopus)
Central Nervous System Diseases
Demyelinating Diseases
2019

Differences between predictive factors for early neurological deterioration due to hemorrhagic and ischemic insults following intravenous recombinant tissue plasminogen activator

Tanaka, K., Matsumoto, S., Furuta, K., Yamada, T., Nagano, S., Takase, K. I., Hatano, T., Yamasaki, R. & Kira, J. I., Jan 1 2019, (Accepted/In press) In : Journal of Thrombosis and Thrombolysis.

Research output: Contribution to journalArticle

Open Access
Tissue Plasminogen Activator
Stroke
Odds Ratio
Confidence Intervals
Tomography
2014
2 Citations (Scopus)

[Disease concept, etiology and mechanisms of multiple sclerosis]

Kira, J. I., Nov 1 2014, In : Nihon rinsho. Japanese journal of clinical medicine. 72, 11, p. 1884-1894 11 p.

Research output: Contribution to journalReview article

Multiple Sclerosis
Central Nervous System
Genes
Th17 Cells
Th1 Cells
2017
8 Citations (Scopus)

Efficacy, safety, and pharmacokinetics of natalizumab in Japanese multiple sclerosis patients: A double-blind, randomized controlled trial and open-label pharmacokinetic study

Saida, T., Kira, J. I., Kishida, S., Yamamura, T., Sudo, Y., Ogiwara, K., Tibung, J. T., Lucas, N. & Subramanyam, M., Jan 1 2017, In : Multiple Sclerosis and Related Disorders. 11, p. 25-31 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Randomized Controlled Trials
Pharmacokinetics
Safety
Relapsing-Remitting Multiple Sclerosis
2016
28 Citations (Scopus)

IgG4 anti-neurofascin155 antibodies in chronic inflammatory demyelinating polyradiculoneuropathy: Clinical significance and diagnostic utility of a conventional assay

Kadoya, M., Kaida, K., Koike, H., Takazaki, H., Ogata, H., Moriguchi, K., Shimizu, J., Nagata, E., Takizawa, S., Chiba, A., Yamasaki, R., Kira, J. I., Sobue, G. & Ikewaki, K., Dec 15 2016, In : Journal of Neuroimmunology. 301, p. 16-22 7 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Anti-Idiotypic Antibodies
Immunoglobulin G
Enzyme-Linked Immunosorbent Assay
Antibodies
2018
7 Citations (Scopus)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Antibodies
Neural Conduction
Immunotherapy
Cerebrospinal Fluid Proteins
2017
2 Citations (Scopus)
Pathologic Nystagmus
Smooth Pursuit
Eye Movements
Mutation
Type 2 Episodic Ataxia
5 Citations (Scopus)

HLA-DRB1*04:05 allele is associated with intracortical lesions on three-dimensional double inversion recovery images in Japanese patients with multiple sclerosis

Shinoda, K., Matsushita, T., Nakamura, Y., Masaki, K., Yamasaki, R., Yamaguchi, H., Togao, O., Hiwatashi, A. & Kira, J-I., May 1 2017, In : Multiple Sclerosis. p. 1352458517707067

Research output: Contribution to journalArticle

Multiple Sclerosis
Alleles
HLA-DRB1 Chains
HLA-DRB1*04 antigen
Logistic Models
2018
2 Citations (Scopus)
Lumbosacral Plexus
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Spinal Ganglia
ROC Curve
Research Ethics Committees
1 Citation (Scopus)

A case of multiple system atrophy-parkinsonian type with stuttering- and palilalia-like dysfluencies and putaminal atrophy

Kikuchi, Y., Umezaki, T., Uehara, T., Yamaguchi, H., Yamashita, K., Hiwatashi, A., Sawatsubashi, M., Adachi, K., Yamaguchi, Y., Murakami, D., Kira, J. I. & Nakagawa, T., Sep 2018, In : Journal of Fluency Disorders. 57, p. 51-58 8 p.

Research output: Contribution to journalArticle

Multiple System Atrophy
Stuttering
Atrophy
deficit
Putamen
2016
19 Citations (Scopus)

A nationwide survey of pediatric acquired demyelinating syndromes in Japan

Yamaguchi, Y., Torisu, H., Kira, R., Ishizaki, Y., Sakai, Y., Sanefuji, M., Ichiyama, T., Oka, A., Kishi, T., Kimura, S., Kubota, M., Takanashi, J., Takahashi, Y., Tamai, H., Natsume, J., Hamano, S., Hirabayashi, S., Maegaki, Y., Mizuguchi, M., Minagawa, K. & 4 others, Yoshikawa, H., Kira, J., Kusunoki, S. & Hara, T., Nov 8 2016, In : Neurology. 87, 19, p. 2006-2015 10 p.

Research output: Contribution to journalArticle

Japan
Acute Disseminated Encephalomyelitis
Neuromyelitis Optica
Pediatrics
Multiple Sclerosis
3 Citations (Scopus)

Requirement of CD30 expression on CD4 T cells in the pathogenesis of experimental autoimmune encephalomyelitis

Shinoda, K., Sun, X., Oyamada, A., Yamada, H., Kira, J. I. & Yoshikai, Y., Feb 15 2016, In : Journal of Neuroimmunology. 291, p. 39-45 7 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
T-Lymphocytes
Th17 Cells
Antigens
Th1 Cells

A case of primary central nervous system vasculitis diagnosed by second brain biopsy and treated successfully

Mizuno, Y., Shigeto, H., Yamada, T., Maeda, N., Suzuki, S. O. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 3, p. 186-190 5 p.

Research output: Contribution to journalArticle

Central Nervous System Vasculitis
Biopsy
Brain
Frontal Lobe
Diplopia
2019

Modified diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomography Score including deep white matter lesions predicts symptomatic intracerebral hemorrhage following intravenous thrombolysis

Tanaka, K., Matsumoto, S., Furuta, K., Yamada, T., Nagano, S., Takase, K. I., Hatano, T., Yamasaki, R. & Kira, J. I., Jan 1 2019, (Accepted/In press) In : Journal of Thrombosis and Thrombolysis.

Research output: Contribution to journalArticle

Open Access
Alberta
Cerebral Hemorrhage
Stroke
Tomography
Tissue Plasminogen Activator
2011
17 Citations (Scopus)

Impact and characteristics of quality of life in Japanese patients with multiple sclerosis

Kikuchi, H., Mifune, N., Niino, M., Ohbu, S., Kira, J. I., Kohriyama, T., Ota, K., Tanaka, M., Ochi, H., Nakane, S., Maezawa, M. & Kikuchi, S., Feb 1 2011, In : Quality of Life Research. 20, 1, p. 119-131 13 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Quality of Life
Social Adjustment
Medical Staff
Focus Groups
2019
3 Citations (Scopus)
Myelin-Oligodendrocyte Glycoprotein
Central Nervous System Vasculitis
Immunotherapy
Antibodies
Cerebrum
2012
22 Citations (Scopus)

First diagnostic criteria for atopic myelitis with special reference to discrimination from myelitis-onset multiple sclerosis

Isobe, N., Kanamori, Y., Yonekawa, T., Matsushita, T., Shigeto, H., Kawamura, N. & Kira, J. I., May 15 2012, In : Journal of the Neurological Sciences. 316, 1-2, p. 30-35 6 p.

Research output: Contribution to journalArticle

Myelitis
Multiple Sclerosis
Oligoclonal Bands
Sensitivity and Specificity
Brain
2017
2 Citations (Scopus)

Structural changes in Parkinson’s disease: voxel-based morphometry and diffusion tensor imaging analyses based on 123I-MIBG uptake

Kikuchi, K., Hiwatashi, A., Togao, O., Yamashita, K., Somehara, R., Kamei, R., Baba, S., Yamaguchi, H., Kira, J. I. & Honda, H., Dec 1 2017, In : European Radiology. 27, 12, p. 5073-5079 7 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Parkinson Disease
Mediastinum
Brain
Myocardial Perfusion Imaging
2019
Chronic Progressive Multiple Sclerosis
Neuroimaging
Cross-Sectional Studies
Oligoclonal Bands
Colony-Stimulating Factor Receptors