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  • Koichi Akashi
2017

Analysis of the variable factors influencing tacrolimus blood concentration during the switch from continuous intravenous infusion to oral administration after allogeneic hematopoietic stem cell transplantation

Suetsugu, K., Ikesue, H., Miyamoto, T., Shiratsuchi, M., Yamamoto-Taguchi, N., Tsuchiya, Y., Matsukawa, K., Uchida, M., Watanabe, H., Akashi, K. & Masuda, S., Mar 1 2017, In : International journal of hematology. 105, 3, p. 361-368 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Shared epitope positivity is related to efficacy of abatacept in rheumatoid arthritis

Oryoji, K., Yoshida, K., Kashiwado, Y., Tanaka, K., Mizuki, S. I., Tsukamoto, H., Kamada, K. & Akashi, K., Aug 1 2018, In : Annals of the Rheumatic Diseases. 77, 8, p. 1234-1236 3 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)
2017
3 Citations (Scopus)

Suggestion of added value by bevacizumab to chemotherapy in patients with unresectable or recurrent small bowel cancer

Takayoshi, K., Kusaba, H., Uenomachi, M., Mitsugi, K., Makiyama, C., Makiyama, A., Uchino, K., Shirakawa, T., Shibata, Y., Shinohara, Y., Inadomi, K., Tsuchihashi, K., Arita, S., Ariyama, H., Esaki, T., Akashi, K. & Baba, E., Aug 1 2017, In : Cancer chemotherapy and pharmacology. 80, 2, p. 333-342 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Twist1 regulates embryonic hematopoietic differentiation through binding to Myb and Gata2 promoter regions

Kulkeaw, K., Inoue, T., Iino, T., Tani, K., Akashi, K., Speck, N. A., Nakanishi, Y. & Sugiyama, D., Sep 12 2017, In : Blood Advances. 1, 20, p. 1672-1681 10 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Microenvironmental immune cell signatures dictate clinical outcomes for PTCL-NOS

Sugio, T., Miyawaki, K., Kato, K., Sasaki, K., Yamada, K., Iqbal, J., Miyamoto, T., Ohshima, K., Maeda, T., Miyoshi, H. & Akashi, K., Sep 11 2018, In : Blood Advances. 2, 17, p. 2242-2252 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2019

PUFA-Plasmalogens Attenuate the LPS-Induced Nitric Oxide Production by Inhibiting the NF-kB, p38 MAPK and JNK Pathways in Microglial Cells

Youssef, M., Ibrahim, A., Akashi, K. & Hossain, M. S., Jan 15 2019, In : Neuroscience. 397, p. 18-30 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., Dec 2018, In : Cancer Science. 109, 12, p. 3874-3882 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy

Kumagai, H., Kusaba, H., Yamanaka, T., Nio, K., Inadomi, K., Takayoshi, K., Ito, M., Tamura, S., Makiyama, A., Makiyama, C., Hirano, G., Shibata, Y., Shirakawa, T., Mitsugi, K., Ariyama, H., Esaki, T., Akashi, K. & Baba, E., Jun 1 2018, In : Medicine (United States). 97, 25, e11042.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2014

Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy Keijiro Ishikawa1

Yoshida, S., Nakao, S., Nakama, T., Kita, T., Asato, R., Sassa, Y., Arita, R., Miyazaki, M., Enaida, H., Oshima, Y., Murakami, N., Niiro, H., Ono, J., Matsuda, A., Goto, Y., Akashi, K., Izuhara, K., Kudo, A., Kono, T., Hafezi-Moghadam, A. & 1 others, Ishibashi, T., Jan 2014, In : FASEB Journal. 28, 1, p. 131-142 12 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2012

Plasma biomarkers of lower gastrointestinal and liver acute GVHD

Harris, A. C., Ferrara, J. L. M., Braun, T. M., Holler, E., Teshima, T., Levine, J. E., Choi, S. W., Landfried, K., Akashi, K., Lugt, M. V., Couriel, D. R., Reddy, P. & Paczesny, S., Mar 22 2012, In : Blood. 119, 12, p. 2960-2963 4 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)
2013

Prevalence and risk factors of vertebral fracture in female Japanese patients with systemic lupus erythematosus

Furukawa, M., Kiyohara, C., Horiuchi, T., Tsukamoto, H., Mitoma, H., Kimoto, Y., Uchino, A., Nakagawa, M., Oryoji, K., Shimoda, T., Harada, M. & Akashi, K., Jul 1 2013, In : Modern Rheumatology. 23, 4, p. 765-773 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2015

The coordinated actions of TIM-3 on cancer and myeloid cells in the regulation of tumorigenicity and clinical prognosis in clear cell renal cell carcinomas

Komohara, Y., Morita, T., Annan, D. A., Horlad, H., Ohnishi, K., Yamada, S., Nakayama, T., Kitada, S., Suzu, S., Kinoshita, I., Dosaka-Akita, H., Akashi, K., Takeya, M. & Jinushi, M., Sep 2015, In : Cancer Immunology Research. 3, 9, p. 999-1007 9 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2013

Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment

Yamauchi, T., Takenaka, K., Urata, S., Shima, T., Kikushige, Y., Tokuyama, T., Iwamoto, C., Nishihara, M., Iwasaki, H., Miyamoto, T., Honma, N., Nakao, M., Matozaki, T. & Akashi, K., Feb 21 2013, In : Blood. 121, 8, p. 1316-1325 10 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)
2015

Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma

Kiyasu, J., Miyoshi, H., Hirata, A., Arakawa, F., Ichikawa, A., Niino, D., Sugita, Y., Yufu, Y., Choi, I., Abe, Y., Uike, N., Nagafuji, K., Okamura, T., Akashi, K., Takayanagi, R., Shiratsuchi, M. & Ohshima, K., Nov 5 2015, In : Blood. 126, 19, p. 2193-2201 9 p.

Research output: Contribution to journalArticle

205 Citations (Scopus)
2017

Persistent detection of alternatively spliced BCR-ABL variant results in a failure to achieve deep molecular response

Yuda, J., Miyamoto, T., Odawara, J., Ohkawa, Y., Semba, Y., Hayashi, M., Miyamura, K., Tanimoto, M., Yamamoto, K., Taniwaki, M. & Akashi, K., Nov 2017, In : Cancer Science. 108, 11, p. 2204-2212 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

Yamauchi, T., Masuda, T., Canver, M. C., Seiler, M., Semba, Y., Shboul, M., Al-Raqad, M., Maeda, M., Schoonenberg, V. A. C., Cole, M. A., Macias-Trevino, C., Ishikawa, Y., Yao, Q., Nakano, M., Arai, F., Orkin, S. H., Reversade, B., Buonamici, S., Pinello, L., Akashi, K. & 2 others, Bauer, D. E. & Maeda, T., Mar 12 2018, In : Cancer Cell. 33, 3, p. 386-400.e5

Research output: Contribution to journalArticle

17 Citations (Scopus)
2015
18 Citations (Scopus)

Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study

Suehiro, Y., Hasegawa, A., Iino, T., Sasada, A., Watanabe, N., Matsuoka, M., Takamori, A., Tanosaki, R., Utsunomiya, A., Choi, I., Fukuda, T., Miura, O., Takaishi, S., Teshima, T., Akashi, K., Kannagi, M., Uike, N. & Okamura, J., May 1 2015, In : British Journal of Haematology. 169, 3, p. 356-367 12 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2020
2015

Successful treatment of adult Langerhans cell histiocytosis with intensified chemotherapy

Minami, M., Shima, T., Kato, K., Yamamoto, H., Tsuchihashi, K., Oku, S., Shimokawa, T., Tochigi, T., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H., Oda, Y., Miyamoto, T. & Akashi, K., Aug 11 2015, In : International journal of hematology. 102, 2, p. 244-248 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

Mogamulizumab Treatment Prior to Allogeneic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-versus-Host Disease

Sugio, T., Kato, K., Aoki, T., Ohta, T., Saito, N., Yoshida, S., Kawano, I., Henzan, H., Kadowaki, M., Takase, K., Muta, T., Miyawaki, K., Yamauchi, T., Shima, T., Takashima, S., Mori, Y., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H. & 6 others, Ogawa, R., Ohno, Y., Eto, T., Kamimura, T., Miyamoto, T. & Akashi, K., Sep 1 2016, In : Biology of Blood and Marrow Transplantation. 22, 9, p. 1608-1614 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2020

Helper T cell-dominant tertiary lymphoid structures are associated with disease relapse of advanced colorectal cancer

Yamaguchi, K., Ito, M., Ohmura, H., Hanamura, F., Nakano, M., Tsuchihashi, K., Nagai, S., Ariyama, H., Kusaba, H., Yamamoto, H., Oda, Y., Nakamura, M., Akashi, K. & Baba, E., Jan 1 2020, In : OncoImmunology. 9, 1, 1724763.

Research output: Contribution to journalArticle

Open Access
2011

Diagnostic value of serum procalcitonin and C-reactive protein for infections after allogeneic hematopoietic stem cell transplantation versus nontransplant setting

Mori, Y., Miyawaki, K., Kato, K., Takenaka, K., Iwasaki, H., Harada, N., Miyamoto, T., Akashi, K. & Teshima, T., Oct 11 2011, In : Internal Medicine. 50, 19, p. 2149-2155 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2015

M2 macrophages enhance pathological neovascularization in the mouse model of oxygen-induced retinopathy

Zhou, Y., Yoshida, S., nakao, S., Yoshimura, T., Kobayashi, Y., Nakama, T., Kubo, Y., Miyawaki, K., Yamaguchi, M., Ishikawa, K., Oshima, Y., Akashi, K. & Ishibashi, T., Jan 1 2015, In : Investigative Ophthalmology and Visual Science. 56, 8, p. 4767-4777 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2018
2 Citations (Scopus)
2016

Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2

Hayashi, M., Maehara, K., Harada, A., Semba, Y., Kudo, K., Takahashi, H., Oki, S., Meno, C., Ichiyanagi, K., Akashi, K. & Ohkawa, Y., Mar 2016, In : Journal of Cellular Biochemistry. 117, 3, p. 780-792 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2017

Systemic chemotherapy with pronounced efficacy and neutropenia in a granulocyte-colony stimulating factor-producingadvanced gastric neuroendocrine carcinoma

Tsuruta, N., Takayoshi, K., Arita, S., Aikawa, T., Ariyama, H., Kusaba, H., Ohuchida, K., Nagai, E., Kohashi, K., Hirahashi, M., Inadomi, K., Tanaka, M., Sagara, K., Okumura, Y., Nio, K., Nakano, M., Nakamura, M., Oda, Y., Akashi, K. & Baba, E., Jan 1 2017, In : Oncology Letters. 14, 2, p. 1500-1504 5 p.

Research output: Contribution to journalArticle

2014

Successful chemoradiotherapy for undifferentiated malignant neoplasm arising from the left pulmonary artery

Kumagai, H., Nio, K., Okumura, Y., Komoda, M., Shirakawa, T., Kusaba, H., Yasuda, S., Odashiro, K., Arita, S., Ariyama, H., Yamada, Y., Yamamoto, H., Oda, Y., Nakamura, K., Akashi, K. & Baba, E., Mar 6 2014, In : Case Reports in Oncology. 7, 2, p. 484-490 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Bi-cytopenia possibly induced by anti-PD-1 antibody for primary malignant melanoma of the esophagus A case report

Inadomi, K., Kumagai, H., Arita, S., Tsuruta, N., Takayoshi, K., Mishima, K., Ota, S. I., Tanaka, M., Okumura, Y., Sagara, K., Nio, K., Nakano, M., Uchi, H., Yamamoto, H., Ariyama, H., Kusaba, H., Niiro, H., Oda, Y., Akashi, K. & Baba, E., Jul 26 2016, In : Medicine (United States). 95, 29, e4283.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2015

A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression

Kikushige, Y., Miyamoto, T., Yuda, J., Jabbarzadeh-Tabrizi, S., Shima, T., Takayanagi, S. I., Niiro, H., Yurino, A., Miyawaki, K., Takenaka, K., Iwasaki, H. & Akashi, K., Sep 3 2015, In : Cell stem cell. 17, 3, p. 341-352 12 p., 1815.

Research output: Contribution to journalArticle

54 Citations (Scopus)
2020

Phase I/II study of bortezomib, lenalidomide, and dexamethasone treatment for relapsed and refractory multiple myeloma

Fukuoka Blood and Marrow Transplantation Group, Jan 1 2020, (Accepted/In press) In : International journal of hematology.

Research output: Contribution to journalArticle

2017

Musashi-1 is the candidate of the regulator of hair cell progenitors during inner ear regeneration

Wakasaki, T., Niiro, H., Jabbarzadeh-Tabrizi, S., Ohashi, M., Kimitsuki, T., Nakagawa, T., Komune, S. & Akashi, K., Aug 16 2017, In : BMC Neuroscience. 18, 1, 64.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody

Yamaguchi, K., Mishima, K., Ohmura, H., Hanamura, F., Ito, M., Nakano, M., Tsuchihashi, K., Ota, S. I., Wada, N., Uchi, H., Ariyama, H., Kusaba, H., Niiro, H., Akashi, K. & Baba, E., Oct 2018, In : Cancer Science. 109, 10, p. 3032-3042 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2015

Amrubicin monotherapy for patients with extrapulmonary neuroendocrine carcinoma after platinum-based chemotherapy

Nio, K., Arita, S., Isobe, T., Kusaba, H., Kohashi, K., Kajitani, T., Tamura, S., Hirano, G., Mitsugi, K., Makiyama, A., Esaki, T., Ariyama, H., Oda, Y., Akashi, K. & Baba, E., Apr 2015, In : Cancer chemotherapy and pharmacology. 75, 4, p. 829-835 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Downregulation of CXCR4 in metastasized breast cancer cells and implication in their dormancy

Nobutani, K., Shimono, Y., Mizutani, K., Ueda, Y., Suzuki, T., Kitayama, M., Minami, A., Momose, K., Miyawaki, K., Akashi, K., Azuma, T. & Takai, Y., Jun 17 2015, In : PloS one. 10, 6, 0130032.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2020

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein–Barr virus-associated gastric cancer

Ohmura, H., Ito, M., Uchino, K., Okada, C., Tanishima, S., Yamada, Y., Momosaki, S., Komoda, M., Kuwayama, M., Yamaguchi, K., Okumura, Y., Nakano, M., Tsuchihashi, K., Isobe, T., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Jan 1 2020, In : FEBS Open Bio. 10, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

Open Access
2017

Identification of unipotent megakaryocyte progenitors in human hematopoiesis

Miyawaki, K., Iwasaki, H., Jiromaru, T., Kusumoto, H., Yurino, A., Sugio, T., Uehara, Y., Odawara, J., Daitoku, S., Kunisaki, Y., Mori, Y., Arinobu, Y., Tsuzuki, H., Kikushige, Y., Iino, T., Kato, K., Takenaka, K., Miyamoto, T., Maeda, T. & Akashi, K., Jun 22 2017, In : Blood. 129, 25, p. 3332-3343 12 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2012

Chd2 interacts with H3.3 to determine myogenic cell fate

Harada, A., Okada, S., Konno, D., Odawara, J., Yoshimi, T., Yoshimura, S., Kumamaru, H., Saiwai, H., Tsubota, T., Kurumizaka, H., Akashi, K., Tachibana, T., Imbalzano, A. N. & Ohkawa, Y., Jul 4 2012, In : EMBO Journal. 31, 13, p. 2994-3007 14 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)
2017

Lingual alveolar soft part sarcoma responsive to pazopanib: A case report

Yoshihiro, T., Tsuchihashi, K., Nio, K., Arita, S., Nakano, T., Yasumatsu, R., Jiroumaru, R., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Nov 2017, In : Medicine (United States). 96, 44, e8470.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non–small cell lung cancer

Hidaka, N., Iwama, E., Kubo, N., Harada, T., Miyawaki, K., Tanaka, K., Okamoto, I., Baba, E., Akashi, K., Sasaki, H. & Nakanishi, Y., Jun 1 2017, In : Lung Cancer. 108, p. 75-82 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2011

Role of autotransplantation in the treatment of acute promyelocytic leukemia patients in remission: Fukuoka BMT Group observations and a literature review

Kamimura, T., Miyamoto, T., Nagafuji, K., Numata, A., Henzan, H., Takase, K., Ito, Y., Ohno, Y., Fujisaki, T., Eto, T., Takamatsu, Y., Teshima, T., Gondo, H., Akashi, K., Taniguchi, S. & Harada, M., Jun 1 2011, In : Bone Marrow Transplantation. 46, 6, p. 820-826 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2013

Autologous peripheral blood stem cell transplantation with granulocyte colony-stimulating factor combined conditioning regimen as a postremission therapy for acute myelogenous leukemia in first complete remission

Eto, T., Takase, K., Miyamoto, T., Ohno, Y., Kamimura, T., Nagafuji, K., Takamatsu, Y., Teshima, T., Gondo, H., Taniguchi, S., Akashi, K. & Harada, M., Aug 1 2013, In : International journal of hematology. 98, 2, p. 186-196 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2011

Modulation of CD4+ T cell responses following splenectomy in hepatitis C virus-related liver cirrhosis

Hashimoto, N., Shimoda, S., Kawanaka, H., Tsuneyama, K., Uehara, H., Akahoshi, T., Kinjo, N., Taketomi, A., Shirabe, K., Akashi, K., Lleo, A., Ansari, A. A., Gershwin, M. E. & Maehara, Y., Aug 1 2011, In : Clinical and Experimental Immunology. 165, 2, p. 243-250 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2012

Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis

Mizuochi, C., Fraser, S. T., Biasch, K., Horio, Y., Kikushige, Y., Tani, K., Akashi, K., Tavian, M. & Sugiyama, D., Apr 27 2012, In : PloS one. 7, 4, e35763.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Coronary and peripheral artery aneurysms in a patient with hypereosinophilia

Fukata, M., Odashiro, K. & Akashi, K., Apr 18 2012, In : Heart Asia. 4, 1, p. 54-55 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2013

Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation

Shima, T., Miyamoto, T., Kikushige, Y., Mori, Y., Kamezaki, K., Takase, K., Henzan, H., Numata, A., Ito, Y., Takenaka, K., Iwasaki, H., Kamimura, T., Eto, T., Nagafuji, K., Teshima, T., Kato, K. & Akashi, K., Jan 31 2013, In : Blood. 121, 5, p. 840-848 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2012

[Diagnostic usefulness of FDG-PET/CT in multiple primary osseous Hodgkin lymphoma].

Kamezaki, K., Harada, Y., Shimono, N., Ohshima, K. & Akashi, K., Dec 2012, In : Unknown Journal. 53, 12, p. 2003-2007 5 p.

Research output: Contribution to journalArticle

2015

Recent advances in therapeutic approaches for adult T-cell leukemia/lymphoma

Kato, K. & Akashi, K., Dec 14 2015, In : Viruses. 7, 12, p. 6604-6612 9 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)
2012

Low incidence of adenovirus hemorrhagic cystitis following autologous hematopoietic stem cell transplantation in the rituximab era

Mori, Y., Miyamoto, T., Kamezaki, K., Kato, K., Kikushige, Y., Takashima, S., Urata, S., Shimoda, S., Shimono, N., Takenaka, K., Iwasaki, H., Nagafuji, K., Teshima, T. & Akashi, K., Aug 1 2012, In : American Journal of Hematology. 87, 8, p. 828-830 3 p.

Research output: Contribution to journalLetter

6 Citations (Scopus)