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2018

Le hazard ou la nécessité? Comorbid pathologies of neurodegenerative diseases

Uchihara, T. & Iwaki, T., Feb 1 2018, In : Neuropathology. 38, 1, p. 62-63 2 p.

Research output: Contribution to journalEditorial

Neurodegenerative Diseases
Pathology
2011
8 Citations (Scopus)

Astrocytopathy in neuromyelitis optica, multiple sclerosis and Baló's disease

Matsushita, T., Masaki, K., Suzuki, S., Matsuoka, T., Yonekawa, T., Wu, X. M., Tabira, T., Iwaki, T. & Kira, J. I., Dec 1 2011, In : Clinical Neurology. 51, 11, p. 898-900 3 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Demyelinating Diseases
Aquaporin 4
Connexin 43
Multiple Sclerosis
2017

Report on an 11-year analysis of neurology autopsy cases: Focusing on neurodegenerative diseases

Fujii, N., Watanabe, A., Arahata, H., Kawano, Y., Sasagasako, N. & Iwaki, T., May 2017, In : IRYO - Japanese Journal of National Medical Services. 71, 5, p. 199-203 5 p.

Research output: Contribution to journalArticle

Tauopathies
Neurology
Neurodegenerative Diseases
Autopsy
2019
Mitochondrial DNA
Mitochondria
Pharmaceutical Preparations
2017

Dura mater graft-associated Creutzfeldt-Jakob disease with 30-year incubation period

Shijo, M., Honda, H., Koyama, S., Ishitsuka, K., Maeda, K., Kuroda, J., Tanii, M., Kitazono, T. & Iwaki, T., Jun 2017, In : Neuropathology. 37, 3, p. 275-281 7 p.

Research output: Contribution to journalArticle

Dura Mater
Creutzfeldt-Jakob Syndrome
Parietal Lobe
Transplants
Pathology
2013
68 Citations (Scopus)
Fluorodeoxyglucose F18
Glioblastoma
Positron-Emission Tomography
Lymphoma
Central Nervous System
2017

A case of suprasellar ganglioglioma arising from the genu‒rostrum of the corpus callosum composed of tumor cells in various stages of neuronal differentiation

Funakoshi, Y., Natori, Y., Suzuki, S., Iwaki, T., Imamoto, N., Yamada, T., Inoue, D., Mori, M., Matsuo, S. & Iwaki, K., Jan 1 2017, In : Japanese Journal of Neurosurgery. 26, 5, p. 362-368 7 p.

Research output: Contribution to journalArticle

Ganglioglioma
Corpus Callosum
Septum Pellucidum
Optic Chiasm
Neoplasms
2013
5 Citations (Scopus)

Pediatric glioblastoma with oligodendroglioma component: Aggressive clinical phenotype with distinct molecular characteristics

Mizoguchi, M., Hata, N., Suzuki, S. O., Fujioka, Y., Murata, H., Amano, T., Nakamizo, A., Yoshimoto, K., Iwaki, T. & Sasaki, T., Dec 2013, In : Neuropathology. 33, 6, p. 652-657 6 p.

Research output: Contribution to journalArticle

Oligodendroglioma
Glioblastoma
temozolomide
Pediatrics
Phenotype
2011
2 Citations (Scopus)

Exacerbation of radiation induced meningioma due to hemorrhage after cerebral angiography: A case report

Yamaguchi, S., Suzuki, S. O., Matsuo, Y., Uesaka, T., Matsukado, K. & Iwaki, T., Jan 1 2011, In : Neurological Surgery. 39, 1, p. 45-50 6 p.

Research output: Contribution to journalArticle

Cerebral Angiography
Hemorrhage
Meningioma
Neoplasms
Hemosiderin
2019
3 Citations (Scopus)
Myelin-Oligodendrocyte Glycoprotein
Central Nervous System Vasculitis
Immunotherapy
Antibodies
Cerebrum
2011
4 Citations (Scopus)

Persistent roles of signal transduction of platelet-derived growth factor B in genesis, growth, and anaplastic transformation of gliomas in an in-vivo serial transplantation model

Torisu, R., Suzuki, S. O., Masui, K., Yoshimoto, K., Mizoguchi, M., Hashizume, M., Canoll, P., Goldman, J. E., Sasaki, T. & Iwaki, T., Feb 1 2011, In : Brain tumor pathology. 28, 1, p. 33-42 10 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-sis
Glioma
Signal Transduction
Transplantation
Growth
2019

Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease

Mori, S., Honda, H., Ishii, T., Yoshimura, M., Sasagasako, N., Suzuki, S. O., Taniwaki, T. & Iwaki, T., Oct 1 2019, In : Neuropathology. 39, 5, p. 358-367 10 p.

Research output: Contribution to journalArticle

Intranuclear Inclusion Bodies
Normal Distribution
Huntington Disease
Sarcoma
Carrier Proteins
Isocitrate Dehydrogenase
Gadolinium
Glioma
Survival
Glioblastoma
2011
22 Citations (Scopus)

An autopsied case of sporadic adult-onset amyotrophic lateral sclerosis with FUS-positive basophilic inclusions

Matsuoka, T., Fujii, N., Kondo, A., Iwaki, A., Hokonohara, T., Honda, H., Sasaki, K., Suzuki, S. O. & Iwaki, T., Feb 1 2011, In : Neuropathology. 31, 1, p. 71-76 6 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Sarcoma
Intermediate Filaments
Genes
Cytomegalovirus Infections
2014
118 Citations (Scopus)

Altered expression of diabetes-related genes in Alzheimer's disease brains: The Hisayama study

Hokama, M., Oka, S., Leon, J., Ninomiya, T., Honda, H., Sasaki, K., Iwaki, T., Ohara, T., Sasaki, T., LaFerla, F. M., Kiyohara, Y. & Nakabeppu, Y., Sep 2014, In : Cerebral Cortex. 24, 9, p. 2476-2488 13 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Brain
Genes
Diabetes Mellitus
Brain Diseases
2011
136 Citations (Scopus)

Midlife and late-life blood pressure and dementia in japanese elderly: The hisayama study

Ninomiya, T., Ohara, T., Hirakawa, Y., Yoshida, D., Doi, Y., Hata, J., Kanba, S., Iwaki, T. & Kiyohara, Y., Jul 1 2011, In : Hypertension. 58, 1, p. 22-28 7 p.

Research output: Contribution to journalArticle

Vascular Dementia
Dementia
Blood Pressure
Hypertension
Alzheimer Disease
13 Citations (Scopus)

Donor-derived adult T-cell leukaemia

Nakamizo, A., Akagi, Y., Amano, T., Suzuki, S. O., Otsuka, R., Abe, Y., Yoshimoto, K., Iwaki, T. & Sasaki, T., Jan 1 2011, In : The Lancet. 377, 9771, 1 p.

Research output: Contribution to journalArticle

HTLV-I Infections
Immunocompetence
Peripheral Blood Stem Cell Transplantation
Carrier State
Adult T Cell Leukemia Lymphoma
2012
Denervation
Motor Neurons
Axotomy
Noxae
Temporal Muscle
2019

Differences between primary central nervous system lymphoma and glioblastoma: topographic analysis using voxel-based morphometry

Yamashita, K., Hiwatashi, A., Togao, O., Kikuchi, K., Momosaka, D., Hata, N., Akagi, Y., Suzuki, S. O., Iwaki, T., Iihara, K. & Honda, H., Oct 2019, In : Clinical Radiology. 74, 10, p. 816.e1-816.e8

Research output: Contribution to journalArticle

Glioblastoma
Lymphoma
Central Nervous System
Software
Corpus Callosum
2017
16 Citations (Scopus)

Discrepancy in programmed cell death-ligand 1 between primary and metastatic non-small cell lung cancer

Takamori, S., Toyokawa, G., Okamoto, I., Takada, K., Kozuma, Y., Matsubara, T., Haratake, N., Akamine, T., Katsura, M., Mukae, N., Shoji, F., Okamoto, T., Oda, Y., Iwaki, T., Iihara, K., Nakanishi, Y. & Maehara, Y., Aug 2017, In : Anticancer research. 37, 8, p. 4223-4228 6 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Death
Ligands
Radiotherapy
Brain
2015
Acute Disseminated Encephalomyelitis
Rubella virus
Rubella
Virus Diseases
2013
14 Citations (Scopus)

TAR DNA-binding protein 43 pathology in a case clinically diagnosed with facial-onset sensory and motor neuronopathy syndrome: An autopsied case report and a review of the literature

Sonoda, K., Sasaki, K., Tateishi, T., Yamasaki, R., Hayashi, S., Sakae, N., Ohyagi, Y., Iwaki, T. & Kira, J. I., Sep 15 2013, In : Journal of the Neurological Sciences. 332, 1-2, p. 148-153 6 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Pathology
Spinal Nerve Roots
Upper Extremity
Autopsy
2018

Four-repeat tau dominant pathology in a congenital myotonic dystrophy type 1 patient with mental retardation

Mizuno, Y., Maeda, N., Hamasaki, H., Arahata, H., Sasagasako, N., Honda, H., Fujii, N. & Iwaki, T., May 2018, In : Brain Pathology. 28, 3, p. 431-433 3 p.

Research output: Contribution to journalLetter

Myotonic Dystrophy
Intellectual Disability
Pathology
2019
Open Access
Tauopathies
Basal Ganglia
Microtubule-Associated Proteins
Alzheimer Disease
Parkinsonian Disorders
2015
20 Citations (Scopus)

Loss of hnRNPA1 in ALS spinal cord motor neurons with TDP-43-positive inclusions

Honda, H., Hamasaki, H., Wakamiya, T., Koyama, S., Suzuki, S. O., Fujii, N. & Iwaki, T., Feb 1 2015, In : Neuropathology. 35, 1, p. 37-43 7 p.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
DNA-Binding Proteins
Motor Neurons
Spinal Cord
Heterogeneous-Nuclear Ribonucleoproteins
2014
7 Citations (Scopus)

Down-regulation of MET in hippocampal neurons of Alzheimer's disease brains

Hamasaki, H., Honda, H., Suzuki, S. O., Hokama, M., Kiyohara, Y., Nakabeppu, Y. & Iwaki, T., Jun 2014, In : Neuropathology. 34, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Hippocampus
Alzheimer Disease
Down-Regulation
Pyramidal Cells
2013
6 Citations (Scopus)

IFPA Meeting 2012 Workshop Report III: Trophoblast deportation, gestational trophoblastic disease, placental insufficiency and fetal growth restriction, trophoblast over-invasion and accreta-related pathologies, placental thrombosis and fibrinolysis

Al-Khan, A., Bulmer, J. N., Chantraine, F., Chen, C. P., Chen, Q., Collins, S., Cotechini, T., Fitzgerald, J. S., He, M., Holland, O., Hung, T. H., Illsley, N. P., Ino, K., Iwaki, T., Kanayama, N., Kaneki, E., Katabuchi, H., Kobayashi, Y., Kondo, A., Masuzaki, H. & 13 others, Matjila, M., Miura, K., Mori, A., Murthi, P., Nagahashi, K., Nie, G., Ohba, T., Sood, R., Sugimura, M., Takizawa, T., Usui, H., Velicky, P. & Lash, G. E., Jan 1 2013, In : Placenta. 34, SUPPL, p. S11-S16

Research output: Contribution to journalArticle

Placental Insufficiency
Gestational Trophoblastic Disease
Trophoblasts
Fibrinolysis
Fetal Development
2019

Clinicopathological review of solitary fibrous tumors: dedifferentiation is a major cause of patient death

Yamada, Y., Kohashi, K., Kinoshita, I., Yamamoto, H., Iwasaki, T., Yoshimoto, M., Ishihara, S., Toda, Y., Itou, Y., Koga, Y., Hashisako, M., Nozaki, Y., Kiyozawa, D., Kitahara, D., Inoue, T., Mukai, M., Honda, Y., Toyokawa, G., Tsuchihashi, K., Matsushita, Y. & 9 others, Fushimi, F., Taguchi, K., Tamiya, S., Oshiro, Y., Furue, M., Nakashima, Y., Suzuki, S., Iwaki, T. & Oda, Y., Oct 1 2019, In : Virchows Archiv. 475, 4, p. 467-477 11 p.

Research output: Contribution to journalArticle

Solitary Fibrous Tumors
Cause of Death
Hypoglycemia
Neoplasms
Central Nervous System
2017
19 Citations (Scopus)

Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Castillo, E., Leon, J., Mazzei, G., Abolhassani, N., Haruyama, N., Saito, T., Saido, T., Hokama, M., Iwaki, T., Ohara, T., Ninomiya, T., Kiyohara, Y., Sakumi, K., Laferla, F. M. & Nakabeppu, Y., Dec 1 2017, In : Scientific reports. 7, 1, 17762.

Research output: Contribution to journalArticle

Gene Expression Profiling
Amyloidosis
Alzheimer Disease
Genes
Neurofibrillary Tangles
2012
30 Citations (Scopus)

Extensive loss of connexins in Baló's disease: Evidence for an auto-antibody-independent astrocytopathy via impaired astrocyte-oligodendrocyte/ myelin interaction

Masaki, K., Suzuki, S. O., Matsushita, T., Yonekawa, T., Matsuoka, T., Isobe, N., Motomura, K., Wu, X. M., Tabira, T., Iwaki, T. & Kira, J. I., Jun 1 2012, In : Acta neuropathologica. 123, 6, p. 887-900 14 p.

Research output: Contribution to journalArticle

Aquaporin 4
Connexins
Oligodendroglia
Myelin Sheath
Astrocytes
2013

The 102nd Neuropathological Meeting of Kyushu District 3 November 2012

Iwaki, T., Apr 1 2013, In : Neuropathology. 33, 2, p. 219 1 p.

Research output: Contribution to journalArticle

2012
13 Citations (Scopus)

Extensive distribution of glial cytoplasmic inclusions in an autopsied case of multiple system atrophy with a prolonged 18-year clinical course

Masui, K., Nakata, Y., Fujii, N. & Iwaki, T., Feb 1 2012, In : Neuropathology. 32, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

Multiple System Atrophy
Inclusion Bodies
Neuroglia
Synucleins
Ubiquitin
2013

Detection of prion protein oligomers by single molecule fluorescence imaging

Shibano, S., Sasaki, K., Kidoaki, S. & Iwaki, T., Feb 1 2013, In : Neuropathology. 33, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Optical Imaging
Polymerization
Fluorescence Microscopy
Prion Diseases
Prions
2016
11 Citations (Scopus)

Sporadic Creutzfeldt-Jakob Disease MM1+2C and MM1 are Identical in Transmission Properties

Kobayashi, A., Matsuura, Y., Iwaki, T., Iwasaki, Y., Yoshida, M., Takahashi, H., Murayama, S., Takao, M., Kato, S., Yamada, M., Mohri, S. & Kitamoto, T., Jan 1 2016, In : Brain Pathology. 26, 1, p. 95-101 7 p.

Research output: Contribution to journalArticle

Prions
Creutzfeldt-Jakob Syndrome
Dura Mater
Valine
Codon
4 Citations (Scopus)

'PrP systemic deposition disease': Clinical and pathological characteristics of novel familial prion disease with 2-bp deletion in codon 178

Matsuzono, K., Honda, H., Sato, K., Morihara, R., Deguchi, K., Hishikawa, N., Yamashita, T., Kono, S., Ohta, Y., Iwaki, T. & Abe, K., Jan 1 2016, In : European Journal of Neurology. 23, 1, p. 196-200 5 p.

Research output: Contribution to journalArticle

Prion Diseases
Codon
Fathers
Restriction Fragment Length Polymorphisms
Siblings
2019
2 Citations (Scopus)

Toxic myopathy with multiple deletions in mitochondrial DNA associated with long-term use of oral anti-viral drugs for hepatitis B: A case study

Fujii, T., Takase, K. I., Honda, H., Kawamura, N., Yamasaki, R., Urata, M., Uchiumi, T., Iwaki, T. & Kira, J. I., Apr 2019, In : Neuropathology. 39, 2, p. 162-167 6 p.

Research output: Contribution to journalArticle

Poisons
Muscular Diseases
Hepatitis B
Mitochondrial DNA
Nucleosides
2012
16 Citations (Scopus)

Molecular characteristics of glioblastoma with 1p/19q co-deletion

Mizoguchi, M., Yoshimoto, K., Ma, X., Guan, Y., Hata, N., Amano, T., Nakamizo, A., Suzuki, S. O., Iwaki, T. & Sasaki, T., Jul 1 2012, In : Brain tumor pathology. 29, 3, p. 148-153 6 p.

Research output: Contribution to journalArticle

Glioblastoma
Isocitrate Dehydrogenase
Loss of Heterozygosity
Oligodendroglioma
Gene Expression
2015
24 Citations (Scopus)

Midlife and late-life smoking and risk of dementia in the community: The Hisayama study

Ohara, T., Ninomiya, T., Hata, J., Ozawa, M., Yoshida, D., Mukai, N., Nagata, M., Iwaki, T., Kitazono, T., Kanba, S. & Kiyohara, Y., Nov 2015, In : Journal of the American Geriatrics Society. 63, 11, p. 2332-2339 8 p.

Research output: Contribution to journalArticle

Dementia
Smoking
Vascular Dementia
Alzheimer Disease
Confidence Intervals
2018
1 Citation (Scopus)

Expression of CRYM in different rat organs during development and its decreased expression in degenerating pyramidal tracts in amyotrophic lateral sclerosis

Hommyo, R., Suzuki, S. O., Abolhassani, N., Hamasaki, H., Shijo, M., Maeda, N., Honda, H., Nakabeppu, Y. & Iwaki, T., Jun 2018, In : Neuropathology. 38, 3, p. 247-259 13 p.

Research output: Contribution to journalArticle

Pyramidal Tracts
Amyotrophic Lateral Sclerosis
Pyramidal Cells
Kidney
Cerebral Cortex
3 Citations (Scopus)

DCTN1 F52L mutation case of Perry syndrome with progressive supranuclear palsy-like tauopathy

Honda, H., Sasagasako, N., Shen, C., Shijo, M., Hamasaki, H., Suzuki, S. O., Tsuboi, Y., Fujii, N. & Iwaki, T., Jun 2018, In : Parkinsonism and Related Disorders. 51, p. 105-110 6 p.

Research output: Contribution to journalArticle

Tauopathies
Progressive Supranuclear Palsy
Parkinsonian Disorders
Hypoventilation
Mutation
2019

Frequent Detection of Pituitary-Derived PrPres in Human Prion Diseases

Honda, H., Matsumoto, M., Shijo, M., Hamasaki, H., Sadashima, S., Suzuki, S. O., Aishima, S., Kai, K., Nakayama, K. I., Sasagasako, N. & Iwaki, T., Oct 1 2019, In : Journal of neuropathology and experimental neurology. 78, 10, p. 922-929 8 p.

Research output: Contribution to journalArticle

Prion Diseases
Human Growth Hormone
Pituitary Gland
Molecular Weight
Dura Mater
2017
38 Citations (Scopus)

Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain

Abolhassani, N., Leon, J., Sheng, Z., Oka, S., Hamasaki, H., Iwaki, T. & Nakabeppu, Y., Jan 15 2017, In : Mechanisms of Ageing and Development. 161, Pt A, p. 95-104 15 p.

Research output: Contribution to journalArticle

DNA Damage
Alzheimer Disease
Glucose
DNA Glycosylases
Brain
2016
15 Citations (Scopus)

Trends in autopsy-verified dementia prevalence over 29 years of the Hisayama study

Honda, H., Sasaki, K., Hamasaki, H., Shijo, M., Koyama, S., Ohara, T., Ninomiya, T., Kiyohara, Y., Suzuki, S. O. & Iwaki, T., Aug 1 2016, In : Neuropathology. 36, 4, p. 383-387 5 p.

Research output: Contribution to journalArticle

Dementia
Autopsy
Alzheimer Disease
Pathology
Life Style
2017
14 Citations (Scopus)

A comprehensive analysis identifies BRAF hotspot mutations associated with gliomas with peculiar epithelial morphology

Hatae, R., Hata, N., Suzuki, S. O., Yoshimoto, K., Kuga, D., Murata, H., Akagi, Y., Sangatsuda, Y., Iwaki, T., Mizoguchi, M. & Iihara, K., Jun 2017, In : Neuropathology. 37, 3, p. 191-199 9 p.

Research output: Contribution to journalArticle

Glioma
Mutation
Glioblastoma
Ganglioglioma
Neuroepithelial Neoplasms
2018
3 Citations (Scopus)
Craniopharyngioma
Freezing
Mutation
Staining and Labeling
Central Nervous System Cysts
2013
28 Citations (Scopus)

Impaired cytoplasmic-nuclear transport of hypoxia-inducible factor-1α in amyotrophic lateral sclerosis

Nagara, Y., Tateishi, T., Yamasaki, R., Hayashi, S., Kawamura, M., Kikuchi, H., Iinuma, K. M., Tanaka, M., Iwaki, T., Matsushita, T., Ohyagi, Y. & Kira, J. I., Sep 1 2013, In : Brain Pathology. 23, 5, p. 534-546 13 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Cell Nucleus Active Transport
Amyotrophic Lateral Sclerosis
Karyopherins
Anterior Horn Cells
43 Citations (Scopus)

Connexin 43 Astrocytopathy Linked to Rapidly Progressive Multiple Sclerosis and Neuromyelitis Optica

Masaki, K., Suzuki, S. O., Matsushita, T., Matsuoka, T., Imamura, S., Yamasaki, R., Suzuki, M., Suenaga, T., Iwaki, T. & Kira, J. I., Aug 22 2013, In : PloS one. 8, 8, e72919.

Research output: Contribution to journalArticle

Neuromyelitis Optica
connexins
Connexin 43
sclerosis
Multiple Sclerosis
2016
46 Citations (Scopus)

Differentiation of high-grade and low-grade diffuse gliomas by intravoxel incoherent motion MR imaging

Togao, O., Hiwatashi, A., Yamashita, K., Kikuchi, K., Mizoguchi, M., Yoshimoto, K., Suzuki, S. O., Iwaki, T., Obara, M., Van Cauteren, M. & Honda, H., Jan 1 2016, In : Neuro-Oncology. 18, 1, p. 132-141 10 p.

Research output: Contribution to journalArticle

Glioma
ROC Curve
Area Under Curve
Perfusion
2012
24 Citations (Scopus)

Arterial spin labeling of hemangioblastoma: Differentiation from metastatic brain tumors based on quantitative blood flow measurement

Yamashita, K., Yoshiura, T., Hiwatashi, A., Togao, O., Yoshimoto, K., Suzuki, S. O., Kikuchi, K., Mizoguchi, M., Iwaki, T. & Honda, H., Aug 1 2012, In : Neuroradiology. 54, 8, p. 809-813 5 p.

Research output: Contribution to journalArticle

Hemangioblastoma
Brain Neoplasms
Neoplasms
Infratentorial Neoplasms
Neoplasm Metastasis
2013
3 Citations (Scopus)

Radiation-induced spinal cord glioblastoma with cerebrospinal fluid dissemination subsequent to treatment of lymphoblastic lymphoma

Kikkawa, Y., Suzuki, S. O., Nakamizo, A., Tsuchimochi, R., Murakami, N., Yoshitake, T., Aishima, S., Okubo, F., Hata, N., Amano, T., Yoshimoto, K., Mizoguchi, M., Iwaki, T. & Sasaki, T., Jan 1 2013, In : Surgical Neurology International. 4, 1, 107905.

Research output: Contribution to journalArticle

Glioblastoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Cerebrospinal Fluid
Spinal Cord
T-Cell Lymphoma