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  • ario takeuchi
2015

Inhibition of the HER2-YB1-AR axis with lapatinib synergistically enhances enzalutamide anti-tumor efficacy in castration resistant prostate cancer

Shiota, M., Bishop, J. L., Takeuchi, A., Nip, K. M., Cordonnier, T., Beraldi, E., Kuruma, H., Gleave, M. E. & Zoubeidi, A., Jan 1 2015, In : Oncotarget. 6, 11, p. 9086-9098 13 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Secondary bladder cancer after anticancer therapy for prostate cancer: Reduced comorbidity after androgen-deprivation therapy

Shiota, M., Yokomizo, A., Takeuchi, A., Imada, K., Kiyoshima, K., Inokuchi, J., Tatsugami, K., Ohga, S., Nakamura, K., Honda, H. & Naito, S., Jan 1 2015, In : Oncotarget. 6, 16, p. 14710-14719 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2014

Risk factors for febrile neutropenia in patients receiving docetaxel chemotherapy for castration-resistant prostate cancer

Shiota, M., Yokomizo, A., Takeuchi, A., Kiyoshima, K., Inokuchi, J., Tatsugami, K. & Naito, S., Jan 1 2014, In : Supportive Care in Cancer. 22, 12, p. 3219-3226 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2012
9 Citations (Scopus)
2017

Smoking effect on oncological outcome among men with prostate cancer after radical prostatectomy

Sato, N., Shiota, M., Shiga, K. I., Takeuchi, A., Inokuchi, J., Tatsugami, K., Yokomizo, A., Koga, H., Yamaguchi, A., Naito, S. & Eto, M., May 1 2017, In : Japanese journal of clinical oncology. 47, 5, p. 453-457 5 p., hyx013.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

External validation of preoperative nomograms predicting lymph node involvement in patients who underwent extended pelvic lymph node dissection during robot-assisted radical prostatectomy

Inokuchi, J., Namitome, R., Kiyoshima, K., Takeuchi, A., Shiota, M., Takahashi, R., Tatsugami, K., Yokomizo, A. & Eto, M., Sep 2016, In : Nishinihon Journal of Urology. 78, 9, p. 451-456 6 p.

Research output: Contribution to journalArticle

2012

Androgen receptor signaling regulates cell growth and vulnerability to doxorubicin in bladder cancer

Shiota, M., Takeuchi, A., Yokomizo, A., Kashiwagi, E., Tatsugami, K., Kuroiwa, K. & Naito, S., Jul 1 2012, In : Journal of Urology. 188, 1, p. 276-286 11 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2019
2 Citations (Scopus)
2017

Tumor-infiltrating lymphocyte-mediated pleuritis followed by marked shrinkage of metastatic kidney cancer of the chest wall during nivolumab treatment

Yanagihara, T., Tanaka, K., Ota, K., Kashiwagi, E., Takeuchi, A., Tatsugami, K., Eto, M., Nakanishi, Y. & Okamoto, I., Aug 1 2017, In : Annals of Oncology. 28, 8, p. 2038-2039 2 p., mdx214.

Research output: Contribution to journalLetter

5 Citations (Scopus)
2013

A C-type lectin receptor pathway is responsible for the pathogenesis of acute cyclophosphamide-induced cystitis in mice

Dejima, T., Shibata, K., Yamada, H., Takeuchi, A., Hara, H., Eto, M., Naito, S. & Yoshikai, Y., Dec 1 2013, In : MICROBIOLOGY and IMMUNOLOGY. 57, 12, p. 833-841 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2011

Statins reduce the androgen sensitivity and cell proliferation by decreasing the androgen receptor protein in prostate cancer cells

Yokomizo, A., Shiota, M., Kashiwagi, E., Kuroiwa, K., Tatsugami, K., Inokuchi, J., Takeuchi, A. & Naito, S., Feb 15 2011, In : Prostate. 71, 3, p. 298-304 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Y-box binding protein-1 promotes castration-resistant prostate cancer growth via androgen receptor expression

Shiota, M., Takeuchi, A., Song, Y. H., Yokomizo, A., Kashiwagi, E., Uchiumi, T., Kuroiwa, K., Tatsugami, K., Fujimoto, N., Oda, Y. & Naito, S., Aug 1 2011, In : Endocrine-Related Cancer. 18, 4, p. 505-517 13 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2014

Inhibition of RSK/YB-1 signaling enhances the anti-cancer effect of enzalutamide in prostate cancer

Shiota, M., Yokomizo, A., Takeuchi, A., Itsumi, M., Imada, K., Kashiwagi, E., Inokuchi, J., Tatsugami, K., Uchiumi, T. & Naito, S., Jun 2014, In : Prostate. 74, 9, p. 959-969 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2017

Gene polymorphisms in antioxidant enzymes correlate with the efficacy of androgen-deprivation therapy for prostate cancer with implications of oxidative stress

Shiota, M., Fujimoto, N., Itsumi, M., Takeuchi, A., Inokuchi, J., Tatsugami, K., Yokomizo, A., Kajioka, S., Uchiumi, T. & Eto, M., Jan 1 2017, In : Annals of Oncology. 28, 3, p. 569-575 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2011

Impact of cold and warm ischemia on postoperative recovery of affected renal function after partial nephrectomy

Tatsugami, K., Eto, M., Yokomizo, A., Kuroiwa, K., Inokuchi, J., Tada, Y., Takeuchi, A., Seki, N. & Naito, S., May 1 2011, In : Journal of Endourology. 25, 5, p. 869-873 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2019

Serum Prognostic Factors of Androgen-deprivation Therapy among Japanese Men with De Novo Metastatic Prostate Cancer

Kobayashi, T., Namitome, R., Hirata, Y., Shiota, M., Imada, K., Kashiwagi, E., Takeuchi, A., Inokuchi, J., Tatsugami, K. & Eto, M., Jan 1 2019, In : Anticancer research. 39, 6, p. 3191-3195 5 p.

Research output: Contribution to journalArticle

2016

Equol inhibits prostate cancer growth through degradation of androgen receptor by S-phase kinase-associated protein 2

Itsumi, M., Shiota, M., Takeuchi, A., Kashiwagi, E., Inokuchi, J., Tatsugami, K., Kajioka, S., Uchiumi, T., Naito, S., Eto, M. & Yokomizo, A., Jul 1 2016, In : Cancer Science. 107, 7, p. 1022-1028 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Prognostic Significance of Preoperative Urine Cytology in Low-grade Non-muscle-invasive Bladder Cancer

Kiyoshima, K., Akitake, M., Shiota, M., Takeuchi, A., Takahashi, R., Inokuchi, J., Tatsugami, K., Yokomizo, A. & Eto, M., Feb 1 2016, In : Anticancer research. 36, 2, p. 799-802 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2015

Crosstalk between epithelialmesenchymal transition and castration resistance mediated by Twist1/AR signaling in prostate cancer

Shiota, M., Itsumi, M., Takeuchi, A., Imada, K., Yokomizo, A., Kuruma, H., Inokuchi, J., Tatsugami, K., Uchiumi, T., Oda, Y. & Naito, S., Dec 2015, In : Endocrine-Related Cancer. 22, 6, p. 889-900 12 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2017

Semaphorin 3 C drives epithelial-to-mesenchymal transition, invasiveness, and stem-like characteristics in prostate cells

Tam, K. J., Hui, D. H. F., Lee, W. W., Dong, M., Tombe, T., Jiao, I. Z. F., Khosravi, S., Takeuchi, A., Peacock, J. W., Ivanova, L., Moskalev, I., Gleave, M. E., Buttyan, R., Cox, M. E. & Ong, C. J., Dec 1 2017, In : Scientific reports. 7, 1, 11501.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2019

Overview of current and future systemic therapy for metastatic renal cell carcinoma

Osawa, T., Takeuchi, A., Kojima, T., Shinohara, N., Eto, M. & Nishiyama, H., Jan 1 2019, In : Japanese journal of clinical oncology. 49, 5, p. 395-403 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

The prognostic impact of serum testosterone during androgen-deprivation therapy in patients with metastatic prostate cancer and the SRD5A2 polymorphism

Shiota, M., Fujimoto, N., Yokomizo, A., Takeuchi, A., Kashiwagi, E., Dejima, T., Kiyoshima, K., Inokuchi, J., Tatsugami, K. & Eto, M., Jun 1 2016, In : Prostate Cancer and Prostatic Diseases. 19, 2, p. 191-196 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2015

SRD5A gene polymorphism in Japanese men predicts prognosis of metastatic prostate cancer with androgen-deprivation therapy

Shiota, M., Fujimoto, N., Yokomizo, A., Takeuchi, A., Itsumi, M., Inokuchi, J., Tatsugami, K., Uchiumi, T. & Naito, S., Jun 17 2015, In : European Journal of Cancer. 51, 14, p. 1962-1969 8 p., 9525.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2014

Inhibition of protein kinase C/twist1 signaling augments anticancer effects of androgen deprivation and enzalutamide in prostate cancer

Shiota, M., Yokomizo, A., Takeuchi, A., Imada, K., Kashiwagi, E., Song, Y., Inokuchi, J., Tatsugami, K., Uchiumi, T. & Naito, S., Feb 26 2014, In : Clinical Cancer Research. 20, 4, p. 951-961 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

PMA induces androgen receptor downregulation and cellular apoptosis in prostate cancer cells

Itsumi, M., Shiota, M., Yokomizo, A., Takeuchi, A., Kashiwagi, E., Dejima, T., Inokuchi, J., Tatsugami, K., Uchiumi, T. & Naito, S., Apr 29 2014, In : Journal of Molecular Endocrinology. 53, 1, p. 31-41 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2020
2019
Open Access
2020
Open Access
2012

Sunitinib enhances antitumor effects against chemotherapy-resistant bladder cancer through suppression of ERK1/2 phosphorylation

Takeuchi, A., Eto, M., Shiota, M., Tatsugami, K., Yokomizo, A., Kuroiwa, K., Itsumi, M. & Naito, S., May 1 2012, In : International journal of oncology. 40, 5, p. 1691-1696 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2019
2013

Interaction between docetaxel resistance and castration resistance in prostate cancer: Implications of Twist1, YB-1, and androgen receptor

Shiota, M., Kashiwagi, E., Yokomizo, A., Takeuchi, A., Dejima, T., Song, Y., Tatsugami, K., Inokuchi, J., Uchiumi, T. & Naito, S., Sep 1 2013, In : Prostate. 73, 12, p. 1336-1344 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2015

Sorafenib enhances the antitumor effects of anti-CTLA-4 antibody in a murine cancer model by inhibiting myeloid-derived suppressor cells

Motoshima, T., Komohara, Y., Horlad, H., Takeuchi, A., Maeda, Y., Tanoue, K., Kawano, Y., Harada, M., Takeya, M. & Eto, M., Jun 1 2015, In : Oncology reports. 33, 6, p. 2947-2953 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2019
2013

YB-1 suppression induces STAT3 proteolysis and sensitizes renal cancer to interferon-α

Takeuchi, A., Shiota, M., Tatsugami, K., Yokomizo, A., Kuroiwa, K., Dejima, T., Tanaka, S., Itsumi, M., Eto, M. & Naito, S., Mar 1 2013, In : Cancer Immunology, Immunotherapy. 62, 3, p. 517-527 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2015

Renal cancer treatment with recipient lymphocyte infusion enhanced the antitumor effect of nonmyeloablative allogeneic stem cell transplantation

Takeuchi, A., Eto, M., Tatsugami, K., Yamada, H., Yokomizo, A., Shiota, M., Itsumi, M., Inokuchi, J., Kiyoshima, K., Dejima, T., Imada, K., Naito, S. & Yoshikai, Y., Mar 1 2015, In : Transplant Immunology. 32, 2, p. 131-139 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2013

Hsp27 regulates epithelial mesenchymal transition, metastasis, and circulating tumor cells in prostate cancer

Shiota, M., Bishop, J. L., Nip, K. M., Zardan, A., Takeuchi, A., Cordonnier, T., Beraldi, E., Bazov, J., Fazli, L., Chi, K., Gleave, M. & Zoubeidi, A., May 15 2013, In : Cancer Research. 73, 10, p. 3109-3119 11 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

Human heterochromatin protein 1 Isoforms regulate androgen receptor signaling in prostate cancer

Itsumi, M., Shiota, M., Yokomizo, A., Kashiwagi, E., Takeuchi, A., Tatsugami, K., Inokuchi, J., Song, Y., Uchiumi, T. & Naito, S., Mar 27 2013, In : Journal of Molecular Endocrinology. 50, 3, p. 401-409 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2012

p300 mediates cellular resistance to doxorubicin in bladder cancer

Takeuchi, A., Shiota, M., Tatsugami, K., Yokomizo, A., Tanaka, S., Kuroiwa, K., Eto, M. & Naito, S., Jan 1 2012, In : Molecular medicine reports. 5, 1, p. 173-176 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2016

Potential role for YB-1 in castration-resistant prostate cancer and resistance to enzalutamide through the androgen receptor V7

Shiota, M., Fujimoto, N., Imada, K., Yokomizo, A., Itsumi, M., Takeuchi, A., Kuruma, H., Inokuchi, J., Tatsugami, K., Uchiumi, T., Oda, Y. & Naito, S., Jan 1 2016, In : Journal of the National Cancer Institute. 108, 7, djw005.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2017

Suppression of LIM and SH3 Domain Protein 1 (LASP1) Negatively Regulated by Androgen Receptor Delays Castration Resistant Prostate Cancer Progression

Dejima, T., Imada, K., Takeuchi, A., Shiota, M., Leong, J., Tombe, T., Tam, K., Fazli, L., Naito, S., Gleave, M. E. & Ong, C. J., Feb 15 2017, In : Prostate. 77, 3, p. 309-320 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

Prognostic Impact of Serum Testosterone and Body Mass Index Before Androgen-deprivation Therapy in Metastatic Prostate Cancer

Shiota, M., Takeuchi, A., Sugimoto, M., Kashiwagi, E., Dejima, T., Kiyoshima, K., Inokuchi, J., Tatsugami, K. & Yokomizo, A., Dec 1 2015, In : Anticancer research. 35, 12, p. 6925-6932 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2017

Protein kinase C regulates Twist1 expression via NF-κB in prostate cancer

Shiota, M., Yokomizo, A., Takeuchi, A., Kashiwagi, E., Dejima, T., Inokuchi, J., Tatsugami, K., Uchiumi, T. & Eto, M., Apr 2017, In : Endocrine-Related Cancer. 24, 4, p. 171-180 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2011

Sorafenib augments cytotoxic effect of S-1 in vitro and in vivo through TS suppression

Takeuchi, A., Shiota, M., Tatsugami, K., Yokomizo, A., Eto, M., Inokuchi, J., Kuroiwa, K., Kiyoshima, K. & Naito, S., Dec 1 2011, In : Cancer chemotherapy and pharmacology. 68, 6, p. 1557-1564 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2019

The impact of genetic polymorphism on CYP19A1 in androgen-deprivation therapy among Japanese men

Shiota, M., Fujimoto, N., Tsukahara, S., Ushijima, M., Takeuchi, A., Kashiwagi, E., Inokuchi, J., Tatsugami, K., Uchiumi, T. & Eto, M., Jan 1 2019, In : Cancer chemotherapy and pharmacology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Immune suppression by PD-L2 against spontaneous and treatment-related antitumor immunity

Tanegashima, T., Togashi, Y., Azuma, K., Kawahara, A., Ideguchi, K., Sugiyama, D., Kinoshita, F., Akiba, J., Kashiwagi, E., Takeuchi, A., Irie, T., Tatsugami, K., Hoshino, T., Eto, M. & Nishikawa, H., Aug 1 2019, In : Clinical Cancer Research. 25, 15, p. 4808-4819 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2015

Low serum testosterone but not obesity predicts high gleason score at biopsy diagnosed as prostate cancer in patients with serum PSA lower than 20 ng/ml

Shiota, M., Takeuchi, A., Sugimoto, M., Dejima, T., Kashiwagi, E., Kiyoshima, K., Inokuchi, J., Tatsugami, K. & Yokomizo, A., Nov 2015, In : Anticancer research. 35, 11, p. 6137-6145 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Differential risk of castration resistance after initial radical prostatectomy or radiotherapy for prostate cancer

Obata, H., Shiota, M., Akitake, N., Takeuchi, A., Kashiwagi, E., Dejima, T., Kiyoshima, K., Inokuchi, J., Tatsugami, K. & Eto, M., Oct 2017, In : Anticancer research. 37, 10, p. 5631-5637 7 p.

Research output: Contribution to journalArticle

2012

Methyltransferase inhibitor adenosine dialdehyde suppresses androgen receptor expression and prostate cancer growth

Shiota, M., Takeuchi, A., Yokomizo, A., Kashiwagi, E., Tatsugami, K. & Naito, S., Jul 1 2012, In : Journal of Urology. 188, 1, p. 300-306 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Antioxidant therapy alleviates oxidative stress by androgen deprivation and prevents conversion from androgen dependent to castration resistant prostate cancer

Shiota, M., Song, Y., Takeuchi, A., Yokomizo, A., Kashiwagi, E., Kuroiwa, K., Tatsugami, K., Uchiumi, T., Oda, Y. & Naito, S., Feb 1 2012, In : Journal of Urology. 187, 2, p. 707-714 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)