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Author

  • Koichi Akashi
2011

[Myeloid lineage commitment from the hematopoietic stem cell].

Arinobu, Y. & Akashi, K., Jul 2011, In : Japanese Journal of Allergology. 60, 7, p. 817-822 6 p.

Research output: Contribution to journalReview article

2013

Nilotinib exacerbates diabetes mellitus by decreasing secretion of endogenous insulin

Ito, Y., Miyamoto, T., Chong, Y., Maki, T., Akashi, K. & Kamimura, T., Jan 1 2013, In : International journal of hematology. 97, 1, p. 135-138 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2018

Erratum: Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack (Blood Adv) (2018) 2:4 (390-400) DOI: 10.1182/bloodadvances.201701334)

Espinoza, J. L., Elbadry, M. I., Chonabayashi, K., Yoshida, Y., Katagiri, T., Harada, K., Nakagawa, N., Zaimoku, Y., Imi, T., Takamatsu, H., Ozawa, T., Maruyama, H., Hassanein, H. A., Noreldin, A. K. A., Takenaka, K., Akashi, K., Hamana, H., Kishi, H., Akatsuka, Y. & Nakao, S., Sep 11 2018, In : Blood Advances. 2, 17, p. 2253 1 p.

Research output: Contribution to journalComment/debate

Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack

Espinoza, J. L., Elbadry, M. I., Chonabayashi, K., Yoshida, Y., Katagiri, T., Harada, K., Nakagawa, N., Zaimoku, Y., Imi, T., Takamatsu, H., Ozawa, T., Maruyama, H., Hassanein, H. A., Noreldin, A. K. A., Takenaka, K., Akashi, K., Hamana, H., Kishi, H., Akatsuka, Y. & Nakao, S., Feb 27 2018, In : Blood Advances. 2, 4, p. 390-400 11 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)
2019

Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells

Tominaga, K., Minato, H., Murayama, T., Sasahara, A., Nishimura, T., Kiyokawa, E., Kanauchi, H., Shimizu, S., Sato, A., Nishioka, K., Tsuji, E. I., Yano, M., Ogawa, T., Ishii, H., Mori, M., Akashi, K., Okamoto, K., Tanabe, M., Tada, K. I., Tojo, A. & 1 others, Gotoh, N., Jan 8 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 2, p. 625-630 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia

Elbadry, M. I., Mizumaki, H., Hosokawa, K., Espinoza, J. L., Nakagawa, N., Yoshida, Y., Katagiri, T., Hosomichi, K., Zaimoku, Y., Imi, T., Nguyen, M. A. T., Fujii, Y., Tajima, A., Ogawa, S., Takenaka, K., Akashi, K. & Nakao, S., 2019, In : Haematologica. 104, 10, p. E447-E450

Research output: Contribution to journalLetter

Open Access
2015

A multinational, open-label, phase 2 study of ruxolitinib in Asian patients with myelofibrosis: Japanese subset analysis

Oritani, K., Okamoto, S., Tauchi, T., Saito, S., Ohishi, K., Handa, H., Takenaka, K., Gopalakrishna, P., Amagasaki, T., Ito, K. & Akashi, K., Mar 6 2015, In : International journal of hematology. 101, 3, p. 295-304 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2018
6 Citations (Scopus)
2017

Manifestation of J wave induced by acetylcholine applied for a coronary spasm provocation test in a patient with aborted sudden cardiac death

Kodama, H., Fujita, K., Moriyama, S., Irie, K., Noda, H., Yokoyama, T., Fukata, M., Arita, T., Odashiro, K., Maruyama, T. & Akashi, K., Jun 2017, In : journal of arrhythmia. 33, 3, p. 234-236 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Assessment of erythrocyte deformability in an obese case of chronic thromboembolic pulmonary hypertension

Yoda, S., Yokoyama, T., Fukata, M., Arita, T., Odashiro, K., Maruyama, T. & Akashi, K., Jan 1 2017, In : Journal of Biorheology. 31, 2, p. 57-60 4 p.

Research output: Contribution to journalArticle

2020
1 Citation (Scopus)
2018

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

Yamauchi, T., Masuda, T., Canver, M. C., Seiler, M., Semba, Y., Shboul, M., Al-Raqad, M., Maeda, M., Schoonenberg, V. A. C., Cole, M. A., Macias-Trevino, C., Ishikawa, Y., Yao, Q., Nakano, M., Arai, F., Orkin, S. H., Reversade, B., Buonamici, S., Pinello, L., Akashi, K. & 2 others, Bauer, D. E. & Maeda, T., Mar 12 2018, In : Cancer Cell. 33, 3, p. 386-400.e5

Research output: Contribution to journalArticle

24 Citations (Scopus)

Microenvironmental immune cell signatures dictate clinical outcomes for PTCL-NOS

Sugio, T., Miyawaki, K., Kato, K., Sasaki, K., Yamada, K., Iqbal, J., Miyamoto, T., Ohshima, K., Maeda, T., Miyoshi, H. & Akashi, K., Sep 11 2018, In : Blood Advances. 2, 17, p. 2242-2252 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

Reduced carotid intima-media thickness in systemic lupus erythematosus patients treated with cyclosporine A

Oryoji, K., Kiyohara, C., Horiuchi, T., Tsukamoto, H., Niiro, H., Shimoda, T., Akashi, K. & Yanase, T., Jan 2014, In : Modern Rheumatology. 24, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2019

Sick sinus syndrome observed in a patient with cholinesterase deficiency

Yasuda, S., Fukata, M., Yokoyama, T., Arita, T., Odashiro, K., Maruyama, T., Hiramoto, Y. & Akashi, K., 2019, In : Internal Medicine. 58, 6, p. 809-812 4 p.

Research output: Contribution to journalArticle

Open Access

Serum levels of fibroblast growth factor-2 distinguish Takayasu arteritis from giant cell arteritis independent of age at diagnosis

Fukui, S., Kuwahara-Takaki, A., Ono, N., Sato, S., Koga, T., Kawashiri, S. Y., Iwanaga, N., Iwamoto, N., Ichinose, K., Tamai, M., Nakamura, H., Origuchi, T., Migita, K., Arinobu, Y., Niiro, H., Tada, Y., Akashi, K., Maeda, T. & Kawakami, A., Dec 1 2019, In : Scientific reports. 9, 1, 688.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018
2 Citations (Scopus)
2017

Musashi-1 is the candidate of the regulator of hair cell progenitors during inner ear regeneration

Wakasaki, T., Niiro, H., Jabbarzadeh-Tabrizi, S., Ohashi, M., Kimitsuki, T., Nakagawa, T., Komune, S. & Akashi, K., Aug 16 2017, In : BMC Neuroscience. 18, 1, 64.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., Dec 2018, In : Cancer Science. 109, 12, p. 3874-3882 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2020

Tyrosine kinase inhibitors induce alternative spliced BCR-ABLIns35bp variant via inhibition of RNA polymerase II on genomic BCR-ABL

Yuda, J., Odawara, J., Minami, M., Muta, T., Kohno, K., Tanimoto, K., Eto, T., Shima, T., Kikushige, Y., Kato, K., Takenaka, K., Iwasaki, H., Minami, Y., Ohkawa, Y., Akashi, K. & Miyamoto, T., Jul 1 2020, In : Cancer Science. 111, 7, p. 2361-2373 13 p.

Research output: Contribution to journalArticle

Open Access
2017

Identification of unipotent megakaryocyte progenitors in human hematopoiesis

Miyawaki, K., Iwasaki, H., Jiromaru, T., Kusumoto, H., Yurino, A., Sugio, T., Uehara, Y., Odawara, J., Daitoku, S., Kunisaki, Y., Mori, Y., Arinobu, Y., Tsuzuki, H., Kikushige, Y., Iino, T., Kato, K., Takenaka, K., Miyamoto, T., Maeda, T. & Akashi, K., Jun 22 2017, In : Blood. 129, 25, p. 3332-3343 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Persistent detection of alternatively spliced BCR-ABL variant results in a failure to achieve deep molecular response

Yuda, J., Miyamoto, T., Odawara, J., Ohkawa, Y., Semba, Y., Hayashi, M., Miyamura, K., Tanimoto, M., Yamamoto, K., Taniwaki, M. & Akashi, K., Nov 2017, In : Cancer Science. 108, 11, p. 2204-2212 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2019

Previous exposure to bortezomib is linked to a lower risk of engraftment syndrome after autologous hematopoietic stem cell transplantation

Mori, Y., Yoshimoto, G., Yuda, J. I., Hayashi, M., Odawara, J., Kuriyama, T., Sugio, T., Miyawaki, K., Kamezaki, K., Kato, K., Takenaka, K., Iwasaki, H., Maeda, T., Miyamoto, T. & Akashi, K., Jan 2 2019, In : Leukemia and Lymphoma. 60, 1, p. 271-273 3 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)
2013

Effectiveness and safety of antiemetic aprepitant in japanese patients receiving high-dose chemotherapy prior to autologous hematopoietic stem cell transplantation

Uchida, M., Ikesue, H., Miyamoto, T., Kato, K., Suetsugu, K., Ichinose, K., Hiraiwa, H., Sakurai, A., Takenaka, K., Muta, T., Iwasaki, H., Teshima, T., Shiratsuchi, M., Egashira, N., Akashi, K. & Oishi, R., May 2013, In : Biological and Pharmaceutical Bulletin. 36, 5, p. 819-824 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2017

Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

Tominaga, K., Shimamura, T., Kimura, N., Murayama, T., Matsubara, D., Kanauchi, H., Niida, A., Shimizu, S., Nishioka, K., Tsuji, E. I., Yano, M., Sugano, S., Shimono, Y., Ishii, H., Saya, H., Mori, M., Akashi, K., Tada, K. I., Ogawa, T., Tojo, A. & 2 others, Miyano, S. & Gotoh, N., Mar 2 2017, In : Oncogene. 36, 9, p. 1276-1286 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2018
1 Citation (Scopus)
2020

Myeloablative intravenous busulfan-containing regimens for allo-HSCT in AML or MDS patients over 54 years old: combined results of three phase II studies

for the Japan Study Group for Cell Therapy, Transplantation (JSCT), 2020, (Accepted/In press) In : International journal of hematology.

Research output: Contribution to journalArticle

2015

Preserved in vivo reconstitution ability of PBSCs cryopreserved for a decade at -80 °c

Shima, T., Iwasaki, H., Yamauchi, T., Kadowaki, M., Kiyosuke, M., Mochimaru, T., Takenaka, K., Miyamoto, T., Akashi, K. & Teshima, T., Sep 4 2015, In : Bone Marrow Transplantation. 50, 9, p. 1195-1200 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2014

Peripheral neuropathy exacerbated by lenalidomide in a patient with multiple myeloma

Kamimura, T., Miyamoto, T., Yokota, N., Aoki, T., Ito, Y. & Akashi, K., Jan 1 2014, In : Internal Medicine. 53, 15, p. 1651-1653 3 p.

Research output: Contribution to journalArticle

Clinical impact of fluoroquinolone-resistant Escherichia coli in the fecal flora of hematological patients with neutropenia and levofloxacin prophylaxis

Chong, Y., Shimoda, S., Yakushiji, H., Ito, Y., Aoki, T., Miyamoto, T., Kamimura, T., Shimono, N. & Akashi, K., Jan 22 2014, In : PloS one. 9, 1, e85210.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2013

Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation

Shima, T., Miyamoto, T., Kikushige, Y., Mori, Y., Kamezaki, K., Takase, K., Henzan, H., Numata, A., Ito, Y., Takenaka, K., Iwasaki, H., Kamimura, T., Eto, T., Nagafuji, K., Teshima, T., Kato, K. & Akashi, K., Jan 31 2013, In : Blood. 121, 5, p. 840-848 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

High incidence and severity of injection site reactions in the first cycle compared with subsequent cycles of subcutaneous bortezomib

Kamimura, T., Miyamoto, T., Yokota, N., Aoki, T., Ito, Y. & Akashi, K., Dec 2013, In : International journal of hematology. 98, 6, p. 694-701 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Reciprocal expression of enteric antimicrobial proteins in intestinal graft-versus-host disease

Eriguchi, Y., Uryu, H., Nakamura, K., Shimoji, S., Takashima, S., Iwasaki, H., Miyamoto, T., Shimono, N., Hashimoto, D., Akashi, K., Ayabe, T. & Teshima, T., Oct 2013, In : Biology of Blood and Marrow Transplantation. 19, 10, p. 1525-1529 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2014

Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioning

Koyama, M., Hashimoto, D., Nagafuji, K., Eto, T., Ohno, Y., Aoyama, K., Iwasaki, H., Miyamoto, T., Hill, G. R., Akashi, K. & Teshima, T., 2014, In : Bone Marrow Transplantation. 49, 1, p. 110-115 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2015

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

Uryu, H., Hashimoto, D., Kato, K., Hayase, E., Matsuoka, S., Ogasawara, R., Takahashi, S., Maeda, Y., Iwasaki, H., Miyamoto, T., Saijo, S., Iwakura, Y., Hill, G. R., Akashi, K. & Teshima, T., 2015, In : Blood. 125, 19, p. 3014-3023 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2013

Evaluation of the feasibility and efficacy of autologous stem cell transplantation in elderly patients with multiple myeloma

Muta, T., Miyamoto, T., Fujisaki, T., Ohno, Y., Kamimura, T., Kato, K., Takenaka, K., Iwasaki, H., Eto, T., Takamatsu, Y., Teshima, T. & Akashi, K., 2013, In : Internal Medicine. 52, 1, p. 63-70 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2017

Early tumor shrinkage indicates a favorable response to bevacizumab-based first-line chemotherapy for metastatic colorectal cancer

Ito, M., Kusaba, H., Mukaide, S., Kishimoto, J., Shimokawa, H., Tamura, S., Makiyama, A., Hirano, G., Oda, H., Shirakawa, T., Komoda, M., Uchino, K., Tanaka, R., Mitsugi, K., Esaki, T., Arita, S., Ariyama, H., Akashi, K. & Baba, E., 2017, In : Anti-cancer drugs. 28, 10, p. 1166-1173 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

The risk factors for oxaliplatin-induced peripheral sensory neuropathy and thrombocytopenia in advanced gastric cancer

Yamaguchi, K., Kusaba, H., Makiyama, A., Mitsugi, K., Uchino, K., Tamura, S., Shibata, Y., Esaki, T., Ito, M., Takayoshi, K., Tsuchihashi, K., Arita, S., Ariyama, H., Akashi, K. & Baba, E., Oct 1 2018, In : Cancer chemotherapy and pharmacology. 82, 4, p. 625-633 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2014

Combination of bortezomib, thalidomide, and dexamethasone (VTD) as a consolidation therapy after autologous stem cell transplantation for symptomatic multiple myeloma in Japanese patients

Takashima, S., Miyamoto, T., Kadowaki, M., Ito, Y., Aoki, T., Takase, K., Shima, T., Yoshimoto, G., Kato, K., Muta, T., Shiratsuchi, M., Takenaka, K., Iwasaki, H., Teshima, T., Kamimura, T. & Akashi, K., Aug 2014, In : International journal of hematology. 100, 2, p. 159-164 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2020

Phase I/II study of bortezomib, lenalidomide, and dexamethasone treatment for relapsed and refractory multiple myeloma

Fukuoka Blood and Marrow Transplantation Group, May 1 2020, In : International journal of hematology. 111, 5, p. 673-680 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Recurrent subcutaneous sweet’s disease in a myelofibrosis patient treated with ruxolitinib before allogeneic stem cell transplantation

Sakoda, T., Kanamitsu, Y., Mori, Y., Sasaki, K., Yonemitsu, E., Nagae, K., Yoshimoto, G., Kamezaki, K., Kato, K., Takenaka, K., Miyamoto, T., Furue, M., Iwasaki, H. & Akashi, K., 2017, In : Internal Medicine. 56, 18, p. 2481-2485 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015
2019

Large-scale genome analysis of bovine commensal Escherichia coli reveals that bovine-adapted E. Coli lineages are serving as evolutionary sources of the emergence of human intestinal pathogenic strains

Arimizu, Y., Kirino, Y., Sato, M. P., Uno, K., Sato, T., Gotoh, Y., Auvray, F., Brugere, H., Oswald, E., Mainil, J. G., Anklam, K. S., Döpfer, D., Yoshino, S., Ooka, T., Tanizawa, Y., Nakamura, Y., Iguchi, A., Morita-Ishihara, T., Ohnishi, M., Akashi, K. & 2 others, Hayashi, T. & Ogura, Y., 2019, In : Genome Research. 29, 9, p. 1495-1505 11 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2020

Combination of CD47 and signal-regulatory protein-α constituting the “don’t eat me signal” is a prognostic factor in diffuse large B-cell lymphoma

Kazama, R., Miyoshi, H., Takeuchi, M., Miyawaki, K., Nakashima, K., Yoshida, N., Kawamoto, K., Yanagida, E., Yamada, K., Umeno, T., Suzuki, T., Kato, K., Takizawa, J., Seto, M., Akashi, K. & Ohshima, K., Jul 1 2020, In : Cancer Science. 111, 7, p. 2608-2619 12 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2014

[Clinical aspects of primary myelofibrosis in Japan].

Shimoda, K., Takenaka, K., Kitanaka, A. & Akashi, K., 2014, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 55, 3, p. 289-294 6 p.

Research output: Contribution to journalReview article

2015

Successful treatment of adult Langerhans cell histiocytosis with intensified chemotherapy

Minami, M., Shima, T., Kato, K., Yamamoto, H., Tsuchihashi, K., Oku, S., Shimokawa, T., Tochigi, T., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H., Oda, Y., Miyamoto, T. & Akashi, K., Aug 11 2015, In : International journal of hematology. 102, 2, p. 244-248 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

Recent advances in the diagnosis and management of primary myelofibrosis

Takenaka, K., Shimoda, K. & Akashi, K., Jul 2018, In : Korean Journal of Internal Medicine. 33, 4, p. 679-690 12 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)
2015

CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: Redefinition of murine common myeloid progenitor

Miyawaki, K., Arinobu, Y., Iwasaki, H., Kohno, K., Tsuzuki, H., Iino, T., Shima, T., Kikushige, Y., Takenaka, K., Miyamoto, T. & Akashi, K., Mar 1 2015, In : STEM CELLS. 33, 3, p. 976-987 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)