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Author

  • Koichi Akashi
2016

Identification of human erythroid lineage-committed progenitors

Mori, Y., Akashi, K. & Weissman, I. L., May 1 2016, In : [Rinsho ketsueki] The Japanese journal of clinical hematology. 57, 5, p. 585-591 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Erratum: Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack (Blood Adv) (2018) 2:4 (390-400) DOI: 10.1182/bloodadvances.201701334)

Espinoza, J. L., Elbadry, M. I., Chonabayashi, K., Yoshida, Y., Katagiri, T., Harada, K., Nakagawa, N., Zaimoku, Y., Imi, T., Takamatsu, H., Ozawa, T., Maruyama, H., Hassanein, H. A., Noreldin, A. K. A., Takenaka, K., Akashi, K., Hamana, H., Kishi, H., Akatsuka, Y. & Nakao, S., Sep 11 2018, In : Blood Advances. 2, 17, p. 2253 1 p.

Research output: Contribution to journalComment/debate

2013

Nilotinib exacerbates diabetes mellitus by decreasing secretion of endogenous insulin

Ito, Y., Miyamoto, T., Chong, Y., Maki, T., Akashi, K. & Kamimura, T., Jan 1 2013, In : International journal of hematology. 97, 1, p. 135-138 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2017

Assessment of erythrocyte deformability in an obese case of chronic thromboembolic pulmonary hypertension

Yoda, S., Yokoyama, T., Fukata, M., Arita, T., Odashiro, K., Maruyama, T. & Akashi, K., Jan 1 2017, In : Journal of Biorheology. 31, 2, p. 57-60 4 p.

Research output: Contribution to journalArticle

2019

Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells

Tominaga, K., Minato, H., Murayama, T., Sasahara, A., Nishimura, T., Kiyokawa, E., Kanauchi, H., Shimizu, S., Sato, A., Nishioka, K., Tsuji, E. I., Yano, M., Ogawa, T., Ishii, H., Mori, M., Akashi, K., Okamoto, K., Tanabe, M., Tada, K. I., Tojo, A. & 1 others, Gotoh, N., Jan 8 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 2, p. 625-630 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2018
6 Citations (Scopus)

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

Yamauchi, T., Masuda, T., Canver, M. C., Seiler, M., Semba, Y., Shboul, M., Al-Raqad, M., Maeda, M., Schoonenberg, V. A. C., Cole, M. A., Macias-Trevino, C., Ishikawa, Y., Yao, Q., Nakano, M., Arai, F., Orkin, S. H., Reversade, B., Buonamici, S., Pinello, L., Akashi, K. & 2 others, Bauer, D. E. & Maeda, T., Mar 12 2018, In : Cancer Cell. 33, 3, p. 386-400.e5

Research output: Contribution to journalArticle

24 Citations (Scopus)
2017

Recurrent subcutaneous sweet’s disease in a myelofibrosis patient treated with ruxolitinib before allogeneic stem cell transplantation

Sakoda, T., Kanamitsu, Y., Mori, Y., Sasaki, K., Yonemitsu, E., Nagae, K., Yoshimoto, G., Kamezaki, K., Kato, K., Takenaka, K., Miyamoto, T., Furue, M., Iwasaki, H. & Akashi, K., 2017, In : Internal Medicine. 56, 18, p. 2481-2485 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack

Espinoza, J. L., Elbadry, M. I., Chonabayashi, K., Yoshida, Y., Katagiri, T., Harada, K., Nakagawa, N., Zaimoku, Y., Imi, T., Takamatsu, H., Ozawa, T., Maruyama, H., Hassanein, H. A., Noreldin, A. K. A., Takenaka, K., Akashi, K., Hamana, H., Kishi, H., Akatsuka, Y. & Nakao, S., Feb 27 2018, In : Blood Advances. 2, 4, p. 390-400 11 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)
2017

Manifestation of J wave induced by acetylcholine applied for a coronary spasm provocation test in a patient with aborted sudden cardiac death

Kodama, H., Fujita, K., Moriyama, S., Irie, K., Noda, H., Yokoyama, T., Fukata, M., Arita, T., Odashiro, K., Maruyama, T. & Akashi, K., Jun 2017, In : journal of arrhythmia. 33, 3, p. 234-236 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2015

A multinational, open-label, phase 2 study of ruxolitinib in Asian patients with myelofibrosis: Japanese subset analysis

Oritani, K., Okamoto, S., Tauchi, T., Saito, S., Ohishi, K., Handa, H., Takenaka, K., Gopalakrishna, P., Amagasaki, T., Ito, K. & Akashi, K., Mar 6 2015, In : International journal of hematology. 101, 3, p. 295-304 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2019

Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia

Elbadry, M. I., Mizumaki, H., Hosokawa, K., Espinoza, J. L., Nakagawa, N., Yoshida, Y., Katagiri, T., Hosomichi, K., Zaimoku, Y., Imi, T., Nguyen, M. A. T., Fujii, Y., Tajima, A., Ogawa, S., Takenaka, K., Akashi, K. & Nakao, S., 2019, In : Haematologica. 104, 10, p. E447-E450

Research output: Contribution to journalLetter

Open Access
2016

The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)

Tsuchihashi, K., Okazaki, S., Ohmura, M., Ishikawa, M., Sampetrean, O., Onishi, N., Wakimoto, H., Yoshikawa, M., Seishima, R., Iwasaki, Y., Morikawa, T., Abe, S., Takao, A., Shimizu, M., Masuko, T., Nagane, M., Furnari, F. B., Akiyama, T., Suematsu, M., Baba, E. & 3 others, Akashi, K., Saya, H. & Nagano, O., May 15 2016, In : Cancer Research. 76, 10, p. 2954-2963 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2012

Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells

Kumamaru, H., Ohkawa, Y., Saiwai, H., Yamada, H., Kubota, K., Kobayakawa, K., Akashi, K., Okano, H., Iwamoto, Y. & Okada, S., 2012, In : Nature communications. 3, 1140.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2018
2 Citations (Scopus)
2019

Serum levels of fibroblast growth factor-2 distinguish Takayasu arteritis from giant cell arteritis independent of age at diagnosis

Fukui, S., Kuwahara-Takaki, A., Ono, N., Sato, S., Koga, T., Kawashiri, S. Y., Iwanaga, N., Iwamoto, N., Ichinose, K., Tamai, M., Nakamura, H., Origuchi, T., Migita, K., Arinobu, Y., Niiro, H., Tada, Y., Akashi, K., Maeda, T. & Kawakami, A., Dec 1 2019, In : Scientific reports. 9, 1, 688.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Quality of life in Japanese female patients with systemic lupus erythematosus: Evaluation using the Short Form 36 Health Survey

Furukawa, M., Kiyohara, C., Horiuchi, T., Tsukamoto, H., Mitoma, H., Kimoto, Y., Uchino, A., Nakagawa, M., Oryoji, K., Shimoda, T. & Akashi, K., Mar 3 2016, In : Modern Rheumatology. 26, 2, p. 240-247 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2014

Reduced carotid intima-media thickness in systemic lupus erythematosus patients treated with cyclosporine A

Oryoji, K., Kiyohara, C., Horiuchi, T., Tsukamoto, H., Niiro, H., Shimoda, T., Akashi, K. & Yanase, T., Jan 2014, In : Modern Rheumatology. 24, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2019

Sick sinus syndrome observed in a patient with cholinesterase deficiency

Yasuda, S., Fukata, M., Yokoyama, T., Arita, T., Odashiro, K., Maruyama, T., Hiramoto, Y. & Akashi, K., 2019, In : Internal Medicine. 58, 6, p. 809-812 4 p.

Research output: Contribution to journalArticle

Open Access
2018

Microenvironmental immune cell signatures dictate clinical outcomes for PTCL-NOS

Sugio, T., Miyawaki, K., Kato, K., Sasaki, K., Yamada, K., Iqbal, J., Miyamoto, T., Ohshima, K., Maeda, T., Miyoshi, H. & Akashi, K., Sep 11 2018, In : Blood Advances. 2, 17, p. 2242-2252 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

Musashi-1 is the candidate of the regulator of hair cell progenitors during inner ear regeneration

Wakasaki, T., Niiro, H., Jabbarzadeh-Tabrizi, S., Ohashi, M., Kimitsuki, T., Nakagawa, T., Komune, S. & Akashi, K., Aug 16 2017, In : BMC Neuroscience. 18, 1, 64.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014

[Clinical aspects of primary myelofibrosis in Japan].

Shimoda, K., Takenaka, K., Kitanaka, A. & Akashi, K., 2014, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 55, 3, p. 289-294 6 p.

Research output: Contribution to journalReview article

2012

Plasma biomarkers of lower gastrointestinal and liver acute GVHD

Harris, A. C., Ferrara, J. L. M., Braun, T. M., Holler, E., Teshima, T., Levine, J. E., Choi, S. W., Landfried, K., Akashi, K., Lugt, M. V., Couriel, D. R., Reddy, P. & Paczesny, S., Mar 22 2012, In : Blood. 119, 12, p. 2960-2963 4 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)
2015

CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: Redefinition of murine common myeloid progenitor

Miyawaki, K., Arinobu, Y., Iwasaki, H., Kohno, K., Tsuzuki, H., Iino, T., Shima, T., Kikushige, Y., Takenaka, K., Miyamoto, T. & Akashi, K., Mar 1 2015, In : STEM CELLS. 33, 3, p. 976-987 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2014

The ordered acquisition of Class II and Class I mutations directs formation of human t(8;21) acute myelogenous leukemia stem cell

Shima, T., Miyamoto, T., Kikushige, Y., Yuda, J., Tochigi, T., Yoshimoto, G., Kato, K., Takenaka, K., Iwasaki, H., Mizuno, S., Goto, N. & Akashi, K., Nov 1 2014, In : Experimental Hematology. 42, 11, p. 955-965.e5

Research output: Contribution to journalArticle

13 Citations (Scopus)
2017

Mobilization of human immature hematopoietic progenitors through combinatory use of bortezomib and immunomodulatory drugs

Tochigi, T., Aoki, T., Kikushige, Y., Kamimura, T., Ito, Y., Shima, T., Yamauchi, T., Mori, Y., Yoshimoto, G., Kamezaki, K., Kato, K., Takenaka, K., Iwasaki, H., Akashi, K. & Miyamoto, T., Apr 1 2017, In : International journal of hematology. 105, 4, p. 423-432 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2015

Successful treatment of adult Langerhans cell histiocytosis with intensified chemotherapy

Minami, M., Shima, T., Kato, K., Yamamoto, H., Tsuchihashi, K., Oku, S., Shimokawa, T., Tochigi, T., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H., Oda, Y., Miyamoto, T. & Akashi, K., Aug 11 2015, In : International journal of hematology. 102, 2, p. 244-248 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2013

Higher incidence of injection site reactions after subcutaneous bortezomib administration on the thigh compared with the abdomen

Kamimura, T., Miyamoto, T., Yokota, N., Takashima, S., Chong, Y., Ito, Y. & Akashi, K., Feb 1 2013, In : European Journal of Haematology. 90, 2, p. 157-161 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2018
2 Citations (Scopus)
2017

Complex regional pain syndrome induced by pacemaker implantation for sick sinus syndrome

Kisanuki, M., Fujita, K., Moriyama, S., Irie, K., Yosida, C., Fukata, M., Arita, T., Yokoyama, T., Odashiro, K., Maruyama, T. & Akashi, K., Dec 2017, In : journal of arrhythmia. 33, 6, p. 643-645 3 p.

Research output: Contribution to journalArticle

2018

Development of a 2-h suicide prevention program for medical staff including nurses and medical residents: A two-center pilot trial

Nakagami, Y., Kubo, H., Katsuki, R., Sakai, T., Sugihara, G., Naito, C., Oda, H., Hayakawa, K., Suzuki, Y., Fujisawa, D., Hashimoto, N., Kobara, K., Cho, T., Kuga, H., Takao, K., Kawahara, Y., Matsumura, Y., Murai, T., Akashi, K., Kanba, S. & 2 others, Otsuka, K. & Kato, T. A., Jan 1 2018, In : Journal of Affective Disorders. 225, p. 569-576 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2013

The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factorα

Ueda, N., Tsukamoto, H., Mitoma, H., Ayano, M., Tanaka, A., Ohta, S. I., Inoue, Y., Arinobu, Y., Niiro, H., Akashi, K. & Horiuchi, T., May 1 2013, In : Inflammatory bowel diseases. 19, 6, p. 1224-1231 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2014

The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment

Iwamoto, C., Takenaka, K., Urata, S., Yamauchi, T., Shima, T., Kuriyama, T., Daitoku, S., Saito, Y., Miyamoto, T., Iwasaki, H., Kitabayashi, I., Itoh, K., Kishimoto, J., Kohda, D., Matozaki, T. & Akashi, K., Mar 2014, In : Experimental Hematology. 42, 3, p. 163-171.e1

Research output: Contribution to journalArticle

20 Citations (Scopus)
2018

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., Dec 2018, In : Cancer Science. 109, 12, p. 3874-3882 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2013

Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment

Yamauchi, T., Takenaka, K., Urata, S., Shima, T., Kikushige, Y., Tokuyama, T., Iwamoto, C., Nishihara, M., Iwasaki, H., Miyamoto, T., Honma, N., Nakao, M., Matozaki, T. & Akashi, K., Feb 21 2013, In : Blood. 121, 8, p. 1316-1325 10 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
2015

Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis

Tanaka, A., Tsukamoto, H., Mitoma, H., Kiyohara, C., Ueda, N., Ayano, M., Ohta, S. I., Kimoto, Y., Akahoshi, M., Arinobu, Y., Niiro, H., Tada, Y., Horiuchi, T. & Akashi, K., Dec 14 2015, In : Arthritis Research and Therapy. 17, 1, 27.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2018

Recent advances in the diagnosis and management of primary myelofibrosis

Takenaka, K., Shimoda, K. & Akashi, K., Jul 2018, In : Korean Journal of Internal Medicine. 33, 4, p. 679-690 12 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)
2017

A Transcriptional Switch Point during Hematopoietic Stem and Progenitor Cell Ontogeny

Sugiyama, D., Joshi, A., Kulkeaw, K., Tan, K. S., Yokoo-Inoue, T., Mizuochi-Yanagi, C., Yasuda, K., Doi, A., Iino, T., Itoh, M., Nagao-Sato, S., Tani, K., Akashi, K., Hayashizaki, Y., Suzuki, H., Kawaji, H., Carninci, P. & Forrest, A. R. R., Mar 1 2017, In : Stem cells and development. 26, 5, p. 314-327 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2012

[Clinical outcomes of allogeneic hematopoietic stem cell transplantation for adult primary myelofibrosis: retrospective analysis by Fukuoka BMT group].

Kamimura, T., Yong, C., Ito, Y., Henzan, H., Miyamoto, T., Ohno, Y., Eto, T., Takenaka, K. & Akashi, K., Mar 2012, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 53, 3, p. 323-328 6 p.

Research output: Contribution to journalReview article

2013

Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation

Shima, T., Miyamoto, T., Kikushige, Y., Mori, Y., Kamezaki, K., Takase, K., Henzan, H., Numata, A., Ito, Y., Takenaka, K., Iwasaki, H., Kamimura, T., Eto, T., Nagafuji, K., Teshima, T., Kato, K. & Akashi, K., Jan 31 2013, In : Blood. 121, 5, p. 840-848 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2014

Peripheral neuropathy exacerbated by lenalidomide in a patient with multiple myeloma

Kamimura, T., Miyamoto, T., Yokota, N., Aoki, T., Ito, Y. & Akashi, K., Jan 1 2014, In : Internal Medicine. 53, 15, p. 1651-1653 3 p.

Research output: Contribution to journalArticle

2013

Reciprocal expression of enteric antimicrobial proteins in intestinal graft-versus-host disease

Eriguchi, Y., Uryu, H., Nakamura, K., Shimoji, S., Takashima, S., Iwasaki, H., Miyamoto, T., Shimono, N., Hashimoto, D., Akashi, K., Ayabe, T. & Teshima, T., Oct 2013, In : Biology of Blood and Marrow Transplantation. 19, 10, p. 1525-1529 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2014

Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioning

Koyama, M., Hashimoto, D., Nagafuji, K., Eto, T., Ohno, Y., Aoyama, K., Iwasaki, H., Miyamoto, T., Hill, G. R., Akashi, K. & Teshima, T., 2014, In : Bone Marrow Transplantation. 49, 1, p. 110-115 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2012

Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells

Uchino, K., Hirano, G., Hirahashi, M., Isobe, T., Shirakawa, T., Kusaba, H., Baba, E., Tsuneyoshi, M. & Akashi, K., Sep 10 2012, In : Experimental Cell Research. 318, 15, p. 1799-1807 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2015

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

Uryu, H., Hashimoto, D., Kato, K., Hayase, E., Matsuoka, S., Ogasawara, R., Takahashi, S., Maeda, Y., Iwasaki, H., Miyamoto, T., Saijo, S., Iwakura, Y., Hill, G. R., Akashi, K. & Teshima, T., 2015, In : Blood. 125, 19, p. 3014-3023 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2013

Evaluation of the feasibility and efficacy of autologous stem cell transplantation in elderly patients with multiple myeloma

Muta, T., Miyamoto, T., Fujisaki, T., Ohno, Y., Kamimura, T., Kato, K., Takenaka, K., Iwasaki, H., Eto, T., Takamatsu, Y., Teshima, T. & Akashi, K., 2013, In : Internal Medicine. 52, 1, p. 63-70 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2015

Preserved in vivo reconstitution ability of PBSCs cryopreserved for a decade at -80 °c

Shima, T., Iwasaki, H., Yamauchi, T., Kadowaki, M., Kiyosuke, M., Mochimaru, T., Takenaka, K., Miyamoto, T., Akashi, K. & Teshima, T., Sep 4 2015, In : Bone Marrow Transplantation. 50, 9, p. 1195-1200 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Composite lymphoma of peripheral T-cell lymphoma and Hodgkin lymphoma, mixed cellularity type; pathological and molecular analysis

Ichikawa, A., Miyoshi, H., Yamauchi, T., Arakawa, F., Kawano, R., Muta, H., Sugita, Y., Akashi, K. & Ohshima, K., Apr 1 2017, In : Pathology International. 67, 4, p. 194-201 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2013

Evaluating the association between histological manifestations of cord colitis syndrome with GVHD

Shimoji, S., Kato, K., Eriguchi, Y., Takenaka, K., Iwasaki, H., Miyamoto, T., Oda, Y., Akashi, K. & Teshima, T., Sep 2013, In : Bone Marrow Transplantation. 48, 9, p. 1249-1252 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)