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  • Koichi Akashi
2019

Sick sinus syndrome observed in a patient with cholinesterase deficiency

Yasuda, S., Fukata, M., Yokoyama, T., Arita, T., Odashiro, K., Maruyama, T., Hiramoto, Y. & Akashi, K., Jan 1 2019, In : Internal Medicine. 58, 6, p. 809-812 4 p.

Research output: Contribution to journalArticle

Open Access

Clinicopathological features of HCV-positive splenic diffuse large B cell lymphoma

Shimono, J., Miyoshi, H., Arakawa, F., Yamada, K., Sugio, T., Miyawaki, K., Eto, T., Miyagishima, T., Kato, K., Nagafuji, K., Akashi, K., Teshima, T. & Ohshima, K., May 1 2019, In : Annals of Hematology. 98, 5, p. 1197-1207 11 p.

Research output: Contribution to journalArticle

2017

Assessment of erythrocyte deformability in an obese case of chronic thromboembolic pulmonary hypertension

Yoda, S., Yokoyama, T., Fukata, M., Arita, T., Odashiro, K., Maruyama, T. & Akashi, K., Jan 1 2017, In : Journal of Biorheology. 31, 2, p. 57-60 4 p.

Research output: Contribution to journalArticle

2016

Retrospective analysis of cardiovascular diseases related to chemotherapies for advanced solid tumor patients

Shirakawa, T., Nakano, M., Nio, K., Tamura, S., Komoda, M., Kumagai, H., Uchino, K., Odashiro, K., Arita, S., Shibata, Y., Ariyama, H., Kusaba, H., Akashi, K. & Baba, E., Sep 1 2016, In : Anti-cancer drugs. 27, 9, p. 891-898 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

Usefulness of medication instruction sheets for sharing information on cancer chemotherapy within the health care team

Uchida, M., Nakamura, T., Watanabe, H., Kato, K., Miyamoto, T., Akashi, K. & Masuda, S., Jan 1 2019, In : Pharmazie. 74, 9, p. 566-569 4 p.

Research output: Contribution to journalArticle

2017

Regorafenib-induced retinal and gastrointestinal hemorrhage in a metastatic colorectal cancer patient with liver dysfunction

Tsuchihashi, K., Shimokawa, H., Takayoshi, K., Nio, K., Aikawa, T., Matsushita, Y., Wada, I., Arita, S., Ariyama, H., Kusaba, H., Sonoda, K. H., Akashi, K. & Baba, E., Oct 1 2017, In : Medicine (United States). 96, 42, e8285.

Research output: Contribution to journalArticle

2016

Peripheral artery disease and omega-3-polyunsaturated fatty acids

Odashiro, K., Fujihara, M., Karashima, E., Mori, T., Koike, A., Kaneko, T., Maruyama, T. & Akashi, K., Jan 1 2016, Peripheral Artery Disease (PAD): Risk Factors, Diagnosis and Emerging Treatments. Nova Science Publishers, Inc., p. 85-100 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Erratum to: Assessing the safety and efficacy of ruxolitinib in a multicenter, open-label study in Japanese patients with myelofibrosis (International Journal of Hematology, (2017), 105, 3, (309-317), 10.1007/s12185-016-2130-z)

Komatsu, N., Kirito, K., Shimoda, K., Ishikawa, T., Ohishi, K., Ohyashiki, K., Takahashi, N., Okada, H., Amagasaki, T., Yonezu, T. & Akashi, K., Mar 1 2017, In : International journal of hematology. 105, 3, 1 p.

Research output: Contribution to journalComment/debate

2019

Evaluation of the compliance with antiemetic guidelines for prevention of chemotherapy-induced nausea and vomiting in patients with hematologic malignancy

Uchida, M., Nakamura, T., Shima, T., Mori, Y., Yoshimoto, G., Kato, K., Shimokawa, M., Hosohata, K., Miyamoto, T. & Akashi, K., Jan 1 2019, In : Pharmazie. 74, 4, p. 250-254 5 p.

Research output: Contribution to journalArticle

2016

Immunosuppressant therapy successfully improved regorafenib-induced severe hepatic injury in a patient with metastatic gastrointestinal stromal tumor: A case report

Kuwayama, M., Uchino, K., Takayoshi, K., Komoda, M., Kohjima, M., Nakamuta, M., Momosaki, S., Kusaba, H., Akashi, K. & Baba, E., Jan 2016, In : Oncology Letters. 11, 1, p. 85-88 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2019

Efficacy and safety of ramucirumab plus modified FOLFIRI for metastatic colorectal cancer

Yoshihiro, T., Kusaba, H., Makiyama, A., Kobayashi, K., Uenomachi, M., Ito, M., Doi, Y., Mitsugi, K., Aikawa, T., Takayoshi, K., Esaki, T., Shimokawa, H., Tsuchihashi, K., Ariyama, H., Akashi, K. & Baba, E., May 15 2019, In : International Journal of Clinical Oncology. 24, 5, p. 508-515 8 p.

Research output: Contribution to journalArticle

2016

The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-)

Tsuchihashi, K., Okazaki, S., Ohmura, M., Ishikawa, M., Sampetrean, O., Onishi, N., Wakimoto, H., Yoshikawa, M., Seishima, R., Iwasaki, Y., Morikawa, T., Abe, S., Takao, A., Shimizu, M., Masuko, T., Nagane, M., Furnari, F. B., Akiyama, T., Suematsu, M., Baba, E. & 3 others, Akashi, K., Saya, H. & Nagano, O., May 15 2016, In : Cancer Research. 76, 10, p. 2954-2963 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2019

Anti-GPRC5D/CD3 bispecific T-cell-redirecting antibody for the treatment of multiple myeloma

Kodama, T., Kochi, Y., Nakai, W., Mizuno, H., Baba, T., Habu, K., Sawada, N., Tsunoda, H., Shima, T., Miyawaki, K., Kikushige, Y., Mori, Y., Miyamoto, T., Maeda, T. & Akashi, K., Jan 1 2019, In : Molecular Cancer Therapeutics. 18, 9, p. 1555-1564 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access
2 Citations (Scopus)
2018

Recent advances in the diagnosis and management of primary myelofibrosis

Takenaka, K., Shimoda, K. & Akashi, K., Jul 2018, In : Korean Journal of Internal Medicine. 33, 4, p. 679-690 12 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer

Makiyama, A., Arimizu, K., Hirano, G., Makiyama, C., Matsushita, Y., Shirakawa, T., Ohmura, H., Komoda, M., Uchino, K., Inadomi, K., Arita, S., Ariyama, H., Kusaba, H., Shinohara, Y., Kuwayama, M., Kajitani, T., Oda, H., Esaki, T., Akashi, K. & Baba, E., May 1 2018, In : Gastric Cancer. 21, 3, p. 464-472 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2020

Myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease

Matsuoka, S., Hashimoto, D., Kadowaki, M., Ohigashi, H., Hayase, E., Yokoyama, E., Hasegawa, Y., Tateno, T., Chen, X., Aoyama, K., Oka, H., Onozawa, M., Takeda, K., Akashi, K. & Teshima, T., Jan 1 2020, In : Haematologica. 105, 1, p. 226-234 9 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2018
2016

Efficacy and safety of TAS-102 in clinical practice of salvage chemotherapy for metastatic colorectal cancer

Arita, S., Shirakawa, T., Matsushita, Y., Shimokawa, H. K., Hirano, G., Makiyama, A., Shibata, Y., Tamura, S., Esaki, T., Mitsugi, K., Ariyama, H., Kusaba, H., Akashi, K. & Baba, E., Apr 2016, In : Anticancer research. 36, 4, p. 1959-1966 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2019

Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells

Tominaga, K., Minato, H., Murayama, T., Sasahara, A., Nishimura, T., Kiyokawa, E., Kanauchi, H., Shimizu, S., Sato, A., Nishioka, K., Tsuji, E. I., Yano, M., Ogawa, T., Ishii, H., Mori, M., Akashi, K., Okamoto, K., Tanabe, M., Tada, K. I., Tojo, A. & 1 others, Gotoh, N., Jan 8 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 2, p. 625-630 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

Analysis of the variable factors influencing tacrolimus blood concentration during the switch from continuous intravenous infusion to oral administration after allogeneic hematopoietic stem cell transplantation

Suetsugu, K., Ikesue, H., Miyamoto, T., Shiratsuchi, M., Yamamoto-Taguchi, N., Tsuchiya, Y., Matsukawa, K., Uchida, M., Watanabe, H., Akashi, K. & Masuda, S., Mar 1 2017, In : International journal of hematology. 105, 3, p. 361-368 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Shared epitope positivity is related to efficacy of abatacept in rheumatoid arthritis

Oryoji, K., Yoshida, K., Kashiwado, Y., Tanaka, K., Mizuki, S. I., Tsukamoto, H., Kamada, K. & Akashi, K., Aug 1 2018, In : Annals of the Rheumatic Diseases. 77, 8, p. 1234-1236 3 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)
2017
3 Citations (Scopus)

Suggestion of added value by bevacizumab to chemotherapy in patients with unresectable or recurrent small bowel cancer

Takayoshi, K., Kusaba, H., Uenomachi, M., Mitsugi, K., Makiyama, C., Makiyama, A., Uchino, K., Shirakawa, T., Shibata, Y., Shinohara, Y., Inadomi, K., Tsuchihashi, K., Arita, S., Ariyama, H., Esaki, T., Akashi, K. & Baba, E., Aug 1 2017, In : Cancer chemotherapy and pharmacology. 80, 2, p. 333-342 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Twist1 regulates embryonic hematopoietic differentiation through binding to Myb and Gata2 promoter regions

Kulkeaw, K., Inoue, T., Iino, T., Tani, K., Akashi, K., Speck, N. A., Nakanishi, Y. & Sugiyama, D., Sep 12 2017, In : Blood Advances. 1, 20, p. 1672-1681 10 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Microenvironmental immune cell signatures dictate clinical outcomes for PTCL-NOS

Sugio, T., Miyawaki, K., Kato, K., Sasaki, K., Yamada, K., Iqbal, J., Miyamoto, T., Ohshima, K., Maeda, T., Miyoshi, H. & Akashi, K., Sep 11 2018, In : Blood Advances. 2, 17, p. 2242-2252 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2019

PUFA-Plasmalogens Attenuate the LPS-Induced Nitric Oxide Production by Inhibiting the NF-kB, p38 MAPK and JNK Pathways in Microglial Cells

Youssef, M., Ibrahim, A., Akashi, K. & Hossain, M. S., Jan 15 2019, In : Neuroscience. 397, p. 18-30 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., Dec 2018, In : Cancer Science. 109, 12, p. 3874-3882 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy

Kumagai, H., Kusaba, H., Yamanaka, T., Nio, K., Inadomi, K., Takayoshi, K., Ito, M., Tamura, S., Makiyama, A., Makiyama, C., Hirano, G., Shibata, Y., Shirakawa, T., Mitsugi, K., Ariyama, H., Esaki, T., Akashi, K. & Baba, E., Jun 1 2018, In : Medicine (United States). 97, 25, e11042.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Persistent detection of alternatively spliced BCR-ABL variant results in a failure to achieve deep molecular response

Yuda, J., Miyamoto, T., Odawara, J., Ohkawa, Y., Semba, Y., Hayashi, M., Miyamura, K., Tanimoto, M., Yamamoto, K., Taniwaki, M. & Akashi, K., Nov 2017, In : Cancer Science. 108, 11, p. 2204-2212 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

Yamauchi, T., Masuda, T., Canver, M. C., Seiler, M., Semba, Y., Shboul, M., Al-Raqad, M., Maeda, M., Schoonenberg, V. A. C., Cole, M. A., Macias-Trevino, C., Ishikawa, Y., Yao, Q., Nakano, M., Arai, F., Orkin, S. H., Reversade, B., Buonamici, S., Pinello, L., Akashi, K. & 2 others, Bauer, D. E. & Maeda, T., Mar 12 2018, In : Cancer Cell. 33, 3, p. 386-400.e5

Research output: Contribution to journalArticle

17 Citations (Scopus)
2020
2016

Mogamulizumab Treatment Prior to Allogeneic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-versus-Host Disease

Sugio, T., Kato, K., Aoki, T., Ohta, T., Saito, N., Yoshida, S., Kawano, I., Henzan, H., Kadowaki, M., Takase, K., Muta, T., Miyawaki, K., Yamauchi, T., Shima, T., Takashima, S., Mori, Y., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H. & 6 others, Ogawa, R., Ohno, Y., Eto, T., Kamimura, T., Miyamoto, T. & Akashi, K., Sep 1 2016, In : Biology of Blood and Marrow Transplantation. 22, 9, p. 1608-1614 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2020

Helper T cell-dominant tertiary lymphoid structures are associated with disease relapse of advanced colorectal cancer

Yamaguchi, K., Ito, M., Ohmura, H., Hanamura, F., Nakano, M., Tsuchihashi, K., Nagai, S., Ariyama, H., Kusaba, H., Yamamoto, H., Oda, Y., Nakamura, M., Akashi, K. & Baba, E., Jan 1 2020, In : OncoImmunology. 9, 1, 1724763.

Research output: Contribution to journalArticle

Open Access
2018
2 Citations (Scopus)
2016

Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2

Hayashi, M., Maehara, K., Harada, A., Semba, Y., Kudo, K., Takahashi, H., Oki, S., Meno, C., Ichiyanagi, K., Akashi, K. & Ohkawa, Y., Mar 2016, In : Journal of Cellular Biochemistry. 117, 3, p. 780-792 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2017

Systemic chemotherapy with pronounced efficacy and neutropenia in a granulocyte-colony stimulating factor-producingadvanced gastric neuroendocrine carcinoma

Tsuruta, N., Takayoshi, K., Arita, S., Aikawa, T., Ariyama, H., Kusaba, H., Ohuchida, K., Nagai, E., Kohashi, K., Hirahashi, M., Inadomi, K., Tanaka, M., Sagara, K., Okumura, Y., Nio, K., Nakano, M., Nakamura, M., Oda, Y., Akashi, K. & Baba, E., Jan 1 2017, In : Oncology Letters. 14, 2, p. 1500-1504 5 p.

Research output: Contribution to journalArticle

2016

Bi-cytopenia possibly induced by anti-PD-1 antibody for primary malignant melanoma of the esophagus A case report

Inadomi, K., Kumagai, H., Arita, S., Tsuruta, N., Takayoshi, K., Mishima, K., Ota, S. I., Tanaka, M., Okumura, Y., Sagara, K., Nio, K., Nakano, M., Uchi, H., Yamamoto, H., Ariyama, H., Kusaba, H., Niiro, H., Oda, Y., Akashi, K. & Baba, E., Jul 26 2016, In : Medicine (United States). 95, 29, e4283.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2020

Phase I/II study of bortezomib, lenalidomide, and dexamethasone treatment for relapsed and refractory multiple myeloma

Fukuoka Blood and Marrow Transplantation Group, Jan 1 2020, (Accepted/In press) In : International journal of hematology.

Research output: Contribution to journalArticle

2017

Musashi-1 is the candidate of the regulator of hair cell progenitors during inner ear regeneration

Wakasaki, T., Niiro, H., Jabbarzadeh-Tabrizi, S., Ohashi, M., Kimitsuki, T., Nakagawa, T., Komune, S. & Akashi, K., Aug 16 2017, In : BMC Neuroscience. 18, 1, 64.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody

Yamaguchi, K., Mishima, K., Ohmura, H., Hanamura, F., Ito, M., Nakano, M., Tsuchihashi, K., Ota, S. I., Wada, N., Uchi, H., Ariyama, H., Kusaba, H., Niiro, H., Akashi, K. & Baba, E., Oct 2018, In : Cancer Science. 109, 10, p. 3032-3042 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2020

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein–Barr virus-associated gastric cancer

Ohmura, H., Ito, M., Uchino, K., Okada, C., Tanishima, S., Yamada, Y., Momosaki, S., Komoda, M., Kuwayama, M., Yamaguchi, K., Okumura, Y., Nakano, M., Tsuchihashi, K., Isobe, T., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Jan 1 2020, In : FEBS Open Bio. 10, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

Open Access
2017

Identification of unipotent megakaryocyte progenitors in human hematopoiesis

Miyawaki, K., Iwasaki, H., Jiromaru, T., Kusumoto, H., Yurino, A., Sugio, T., Uehara, Y., Odawara, J., Daitoku, S., Kunisaki, Y., Mori, Y., Arinobu, Y., Tsuzuki, H., Kikushige, Y., Iino, T., Kato, K., Takenaka, K., Miyamoto, T., Maeda, T. & Akashi, K., Jun 22 2017, In : Blood. 129, 25, p. 3332-3343 12 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Lingual alveolar soft part sarcoma responsive to pazopanib: A case report

Yoshihiro, T., Tsuchihashi, K., Nio, K., Arita, S., Nakano, T., Yasumatsu, R., Jiroumaru, R., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Nov 2017, In : Medicine (United States). 96, 44, e8470.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non–small cell lung cancer

Hidaka, N., Iwama, E., Kubo, N., Harada, T., Miyawaki, K., Tanaka, K., Okamoto, I., Baba, E., Akashi, K., Sasaki, H. & Nakanishi, Y., Jun 1 2017, In : Lung Cancer. 108, p. 75-82 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2019

Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial

TOURMALINE-MM3 study group, Jan 19 2019, In : The Lancet. 393, 10168, p. 253-264 12 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2016

Cord blood transplantation following reduced-intensity conditioning for adult-onset inherited hemophagocytic lymphohistiocytosis

Kuriyama, T., Kato, K., Sakamoto, K., Hayashi, M., Takashima, S., Mori, Y., Takenaka, K., Iwasaki, H., Teshima, T., Harada, N., Nagafuji, K., Miyamoto, T. & Akashi, K., Mar 15 2016, In : Internal Medicine. 55, 6, p. 667-671 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Chronic myelomonocytic leukemia blast crisis in a patient with advanced non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors

Ogata, H., Okamoto, I., Yoshimoto, G., Obara, T., Ijichi, K., Iwama, E., Harada, T., Akashi, K. & Nakanishi, Y., Mar 1 2017, In : Respiratory Investigation. 55, 2, p. 181-183 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Adult T-Cell Leukemia After Deceased Donor Liver Transplantation for Acute Liver Failure: A Case Report

Motomura, T., Yoshizumi, T., Kosai-Fujimoto, Y., Mano, Y., Toshima, T., Takeishi, K., Itoh, S., Harada, N., Ikegami, T., Soejima, Y., Yoshimoto, G., Akashi, K. & Mori, M., Jul 1 2019, In : Transplantation Proceedings. 51, 6, p. 1978-1981 4 p.

Research output: Contribution to journalArticle