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• 2011

  [Lymphoid malignancies: progress in diagnosis and treatment. Topics: I. Pathogenesis and pathophysiology--recent findings; 1. Leukemia stem cells in acute lymphoblastic leukemia].

  Takenaka, K. & Akashi, K., Jul 10 2011, In: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 100, 7, p. 1753-1764 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• [Myeloid lineage commitment from the hematopoietic stem cell].

  Arinobu, Y. & Akashi, K., Jul 2011, In: Japanese Journal of Allergology. 60, 7, p. 817-822 6 p.

  Research output: Contribution to journal › Review article › peer-review

• [Specific surface markers of AML-leukemic stem cells].

  Kikushige, Y., Miyamoto, T. & Akashi, K., Jul 1 2011, In: [Rinshō ketsueki] The Japanese journal of clinical hematology. 52, 7, p. 531-534 4 p.

  Research output: Contribution to journal › Review article › peer-review

• Advances in therapies for acute promyelocytic leukemia

  Kamimura, T., Miyamoto, T., Harada, M. & Akashi, K., Nov 2011, In: Cancer Science. 102, 11, p. 1929-1937 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Acute Promyelocytic Leukemia
  • Retinoic Acid Receptors
  • Leukemia
  • Anthracyclines
  • Tretinoin
  40 Citations (Scopus)

• Analysis of immune reconstitution after autologous CD34 ⁺ stem/progenitor cell transplantation for systemic sclerosis: Predominant reconstitution of Th1 CD4 ⁺ t cells

  Tsukamoto, H., Nagafuji, K., Horiuchi, T., Mitoma, H., Niiro, H., Arinobu, Y., Inoue, Y., To, K., Miyamoto, T., Iwasaki, H., Teshima, T., Harada, M. & Akashi, K., May 2011, In: Rheumatology. 50, 5, p. 944-952 9 p., keq414.

  Research output: Contribution to journal › Article › peer-review

  • Immune Reconstitution
  • Systemic Scleroderma
  • Hematopoietic Stem Cell Transplantation
  • Stem Cell Transplantation
  • Stem Cells
  37 Citations (Scopus)

• Clinical features and outcomes of 35 disseminated intravascular coagulation cases treated with recombinant human soluble thrombomodulin at a single institution.

  Kawano, N., Yoshida, S., Ono, N., Himeji, D., Nagahiro, Y., Sayaka Kawano, K., Yamashita, K., Ikeda, N., Uezono, S., Ochiai, H., Kawano, F., Kikuchi, I., Ishikawa, F., Shimoda, K., Ueda, A. & Akashi, K., 2011, In: Journal of clinical and experimental hematopathology : JCEH. 51, 2, p. 101-107 7 p.

  Research output: Contribution to journal › Article › peer-review

  • human THBD protein
  • Disseminated Intravascular Coagulation
  • Hematologic Diseases
  • Communicable Diseases
  • Hemorrhage
  18 Citations (Scopus)

• Clonal origin of Epstein-Barr virus (EBV)-infected T/NK-cell subpopulations in EBV-positive T/NK-cell lymphoproliferative disorders of childhood

  Ohga, S., Ishimura, M., Yoshimoto, G., Miyamoto, T., Takada, H., Tanaka, T., Ohshima, K., Ogawa, Y., Imadome, K. I., Abe, Y., Akashi, K. & Hara, T., May 2011, In: Journal of Clinical Virology. 51, 1, p. 31-37 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Lymphoproliferative Disorders
  • Human Herpesvirus 4
  • Natural Killer Cells
  • T-Lymphocytes
  • T-Lymphocyte Subsets
  14 Citations (Scopus)

• Correlation between pretreatment or follow-up CT findings and therapeutic effect of autologous peripheral blood stem cell transplantation for interstitial pneumonia associated with systemic sclerosis

  Yabuuchi, H., Matsuo, Y., Tsukamoto, H., Sunami, S., Kamitani, T., Sakai, S., Hatakenaka, M., Nagafuji, K., Horiuchi, T., Harada, M., Akashi, K. & Honda, H., Aug 2011, In: European Journal of Radiology. 79, 2, p. e74-e79

  Research output: Contribution to journal › Article › peer-review

  • Peripheral Blood Stem Cell Transplantation
  • Systemic Scleroderma
  • Interstitial Lung Diseases
  • Glass
  • Therapeutic Uses
  7 Citations (Scopus)

• Diagnostic value of serum procalcitonin and C-reactive protein for infections after allogeneic hematopoietic stem cell transplantation versus nontransplant setting

  Mori, Y., Miyawaki, K., Kato, K., Takenaka, K., Iwasaki, H., Harada, N., Miyamoto, T., Akashi, K. & Teshima, T., 2011, In: Internal Medicine. 50, 19, p. 2149-2155 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Procalcitonin
  • Hematopoietic Stem Cell Transplantation
  • C-Reactive Protein
  • Infection
  • Serum
  12 Citations (Scopus)

• Human STEAP3 maintains tumor growth under hypoferric condition

  Isobe, T., Baba, E., Arita, S., Komoda, M., Tamura, S., Shirakawa, T., Ariyama, H., Takaishi, S., Kusaba, H., Ueki, T. & Akashi, K., Nov 1 2011, In: Experimental Cell Research. 317, 18, p. 2582-2591 10 p.

  Research output: Contribution to journal › Article › peer-review

  • human STEAP1 protein
  • Prostate
  • Iron
  • Antigens
  • Growth
  15 Citations (Scopus)

• Impaired deformability of erythrocytes in diabetic rat and human: Investigation by the nickel-mesh-filtration technique

  Saito, K., Kogawa, Y., Fukata, M., Odashiro, K., Maruyama, T., Akashi, K. & Fujino, T., Dec 2011, In: Journal of Biorheology. 25, 1-2, p. 18-26 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Nickel
  • Rats
  • Formability
  • Rat control
  • Microcirculation
  6 Citations (Scopus)

• Influence of common cardiac drugs on gastroesophageal reflux disease: Multicenter questionnaire survey

  Nakaji, G., Fujihara, M., Fukata, M., Yasuda, S., Odashiro, K., Maruyama, T. & Akashi, K., Sep 2011, In: International Journal of Clinical Pharmacology and Therapeutics. 49, 9, p. 555-563 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastroesophageal Reflux
  • Calcium Channel Blockers
  • Pharmaceutical Preparations
  • Warfarin
  • Medicine
  7 Citations (Scopus)

• Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis

  Shimoda, S., Harada, K., Niiro, H., Shirabe, K., Taketomi, A., Maehara, Y., Tsuneyama, K., Nakanuma, Y., Leung, P., Ansari, A. A., Gershwin, M. E. & Akashi, K., Apr 2011, In: Hepatology. 53, 4, p. 1270-1281 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Biliary Liver Cirrhosis
  • Toll-Like Receptors
  • Bile Ducts
  • Natural Killer Cells
  • Ligands
  88 Citations (Scopus)

• Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin

  Hirano, G., Izumi, H., Yasuniwa, Y., Shimajiri, S., Ke-Yong, W., Sasagiri, Y., Kusaba, H., Matsumoto, K., Hasegawa, T., Akimoto, M., Akashi, K. & Kohno, K., Apr 2011, In: International journal of oncology. 38, 4, p. 893-902 10 p.

  Research output: Contribution to journal › Article › peer-review

  • riboflavin kinase
  • Cisplatin
  • Flavin-Adenine Dinucleotide
  • Glutathione Reductase
  • Flavin Mononucleotide
  14 Citations (Scopus)

• Modulation of CD4⁺ T cell responses following splenectomy in hepatitis C virus-related liver cirrhosis

  Hashimoto, N., Shimoda, S., Kawanaka, H., Tsuneyama, K., Uehara, H., Akahoshi, T., Kinjo, N., Taketomi, A., Shirabe, K., Akashi, K., Lleo, A., Ansari, A. A., Gershwin, M. E. & Maehara, Y., Aug 2011, In: Clinical and Experimental Immunology. 165, 2, p. 243-250 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Splenectomy
  • Liver Cirrhosis
  • Hepacivirus
  • T-Lymphocytes
  • Thrombocytopenia
  26 Citations (Scopus)

• Myeloid lineage commitment from the hematopoietic stem cell

  Arinobu, Y. & Akashi, K., Dec 1 2011, In: Japanese Journal of Allergology. 60, 7, p. 817-822 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Phase II study of sequential treatment with S-1 and cisplatin for metastatic gastric cancer

  Baba, E., Esaki, T., Ariyama, H., Mitsugi, K., Morikita, T., Fujishima, H., Kusaba, H., Nakano, S. & Akashi, K., Sep 2011, In: Cancer chemotherapy and pharmacology. 68, 3, p. 611-617 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cisplatin
  • Stomach Neoplasms
  • Oncology
  • Terminology
  • Tumors
  3 Citations (Scopus)

• PJ3-064 A Case of Various Supraventricular and Ventricular Tachyarrhythmias Secondary to Polymyositis

  Yasuda, S., Kokawa, Y., Nakamura, H., Fukata, M., Odashiro, K., Maruyama, T. & Akashi, K., 2011, In: journal of arrhythmia. 27

  Research output: Contribution to journal › Article › peer-review

  • Polymyositis
  • Polyvinyl Chloride
  • Tachycardia
  • Catheter Ablation
  • Myocarditis

• Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus

  Furukawa, M., Kiyohara, C., Tsukamoto, H., Mitoma, H., Kimoto, Y., Uchino, A., Nakagawa, M., Oryoji, K., Shimoda, T., Akashi, K., Harada, M. & Horiuchi, T., Mar 2011, In: Rheumatology International. 31, 3, p. 365-376 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Systemic Lupus Erythematosus
  • Bone Density
  • Spine
  • Metabolic Bone Diseases
  • Hip
  10 Citations (Scopus)

• Regenerating islet-derived 3-alpha is a biomarker of gastrointestinal graft-versus-host disease

  Ferrara, J. L. M., Harris, A. C., Greenson, J. K., Braun, T. M., Holler, E., Teshima, T., Levine, J. E., Choi, S. W. J., Huber, E., Landfried, K., Akashi, K., Vander Lugt, M., Reddy, P., Chin, A., Zhang, Q., Hanash, S. & Paczesny, S., Dec 15 2011, In: Blood. 118, 25, p. 6702-6708 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Grafts
  • Biomarkers
  • Graft vs Host Disease
  • Plasmas
  • Cell Transplantation
  188 Citations (Scopus)

• Relationship between atrial fibrillation and gastroesophageal reflux disease: A multicenter questionnaire survey

  Shimazu, H., Nakaji, G., Fukata, M., Odashiro, K., Maruyama, T. & Akashi, K., Nov 2011, In: Cardiology. 119, 4, p. 217-223 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastroesophageal Reflux
  • Atrial Fibrillation
  • Dyslipidemias
  • Informed Consent
  • Medical Records
  16 Citations (Scopus)

• Role of autotransplantation in the treatment of acute promyelocytic leukemia patients in remission: Fukuoka BMT Group observations and a literature review

  Kamimura, T., Miyamoto, T., Nagafuji, K., Numata, A., Henzan, H., Takase, K., Ito, Y., Ohno, Y., Fujisaki, T., Eto, T., Takamatsu, Y., Teshima, T., Gondo, H., Akashi, K., Taniguchi, S. & Harada, M., Jun 2011, In: Bone Marrow Transplantation. 46, 6, p. 820-826 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Acute Promyelocytic Leukemia
  • Autologous Transplantation
  • Therapeutics
  • Consolidation Chemotherapy
  • Tretinoin
  13 Citations (Scopus)

• Self-Renewing Hematopoietic Stem Cell Is the Primary Target in Pathogenesis of Human Chronic Lymphocytic Leukemia

  Kikushige, Y., Ishikawa, F., Miyamoto, T., Shima, T., Urata, S., Yoshimoto, G., Mori, Y., Iino, T., Yamauchi, T., Eto, T., Niiro, H., Iwasaki, H., Takenaka, K. & Akashi, K., Aug 16 2011, In: Cancer Cell. 20, 2, p. 246-259 14 p.

  Research output: Contribution to journal › Article › peer-review

  • B-Cell Chronic Lymphocytic Leukemia
  • Hematopoietic Stem Cells
  • Clone Cells
  • B-Lymphocytes
  • Immunoglobulin Genes
  179 Citations (Scopus)

• Successful allogeneic stem cell transplantation in two patients with acute myelogenous leukaemia and invasive aspergillosis by antifungal combination therapy

  Aoki, T., Miyamoto, T., Mori, Y., Yoshimoto, G., Yamauchi, T., Kamezaki, K., Takenaka, K., Iwasaki, H., Harada, N., Nagafuji, K., Shimono, N., Teshima, T. & Akashi, K., Jul 2011, In: Mycoses. 54, 4, p. e255-e259

  Research output: Contribution to journal › Letter › peer-review

  • Aspergillosis
  • Hematopoietic Stem Cell Transplantation
  • Allogeneic Cells
  • Stem Cell Transplantation
  • Acute Myeloid Leukemia
  4 Citations (Scopus)

• The classification of mRNA expression levels by the phosphorylation state of RNAPII CTD based on a combined genome-wide approach

  Odawara, J., Harada, A., Yoshimi, T., Maehara, K., Tachibana, T., Okada, S., Akashi, K. & Ohkawa, Y., Oct 20 2011, In: BMC genomics. 12, 516.

  Research output: Contribution to journal › Article › peer-review

  • RNA Polymerase II
  • Phosphorylation
  • Genome
  • Messenger RNA
  • Catalytic RNA
  27 Citations (Scopus)

• The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells

  Takashima, S., Kadowaki, M., Aoyama, K., Koyama, M., Oshima, T., Tomizuka, K., Akashi, K. & Teshima, T., Feb 14 2011, In: Journal of Experimental Medicine. 208, 2, p. 285-294 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Graft vs Host Disease
  • Stem Cells
  • Homologous Transplantation
  • Bone Marrow Transplantation
  • Intestinal Mucosa
  85 Citations (Scopus)
• 2015

  A case of Candida albicans fungus balls in the urinary tract appeared during the course of antifungal treatment for Candida endophthalmitis

  Onozawa, K., Miyake, N., Iwasaki, N., Nishida, R., Chong, Y., Shimoda, S., Shimono, N. & Akashi, K., Sep 1 2015, In: Journal of Infection and Chemotherapy. 21, 9, p. 687-690 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Endophthalmitis
  • Antifungal Agents
  • Candida
  • Candida albicans
  • Urinary Tract

• A dramatic increase in the positive blood culture rates of Helicobacter cinaedi: The evidence of differential detection abilities between the Bactec and BacT/Alert systems

  Miyake, N., Chong, Y., Nishida, R., Nagasaki, Y., Kibe, Y., Kiyosuke, M., Shimomura, T., Shimono, N., Shimoda, S. & Akashi, K., Nov 2015, In: Diagnostic Microbiology and Infectious Disease. 83, 3, p. 232-233 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Helicobacter
  • Blood Culture
  • Bacteremia
  • Growth
  9 Citations (Scopus)

• Amrubicin monotherapy for patients with extrapulmonary neuroendocrine carcinoma after platinum-based chemotherapy

  Nio, K., Arita, S., Isobe, T., Kusaba, H., Kohashi, K., Kajitani, T., Tamura, S., Hirano, G., Mitsugi, K., Makiyama, A., Esaki, T., Ariyama, H., Oda, Y., Akashi, K. & Baba, E., Apr 2015, In: Cancer chemotherapy and pharmacology. 75, 4, p. 829-835 7 p.

  Research output: Contribution to journal › Article › peer-review

  • amrubicin
  • Chemotherapy
  • Neuroendocrine Carcinoma
  • Platinum
  • Drug Therapy
  10 Citations (Scopus)

• A multinational, open-label, phase 2 study of ruxolitinib in Asian patients with myelofibrosis: Japanese subset analysis

  Oritani, K., Okamoto, S., Tauchi, T., Saito, S., Ohishi, K., Handa, H., Takenaka, K., Gopalakrishna, P., Amagasaki, T., Ito, K. & Akashi, K., Mar 6 2015, In: International journal of hematology. 101, 3, p. 295-304 10 p.

  Research output: Contribution to journal › Article › peer-review

  • INCB018424
  • Primary Myelofibrosis
  • Splenomegaly
  • Janus Kinase 1
  • Nasopharyngitis
  14 Citations (Scopus)

• A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression

  Kikushige, Y., Miyamoto, T., Yuda, J., Jabbarzadeh-Tabrizi, S., Shima, T., Takayanagi, S. I., Niiro, H., Yurino, A., Miyawaki, K., Takenaka, K., Iwasaki, H. & Akashi, K., Sep 3 2015, In: Cell stem cell. 17, 3, p. 341-352 12 p., 1815.

  Research output: Contribution to journal › Article › peer-review

  • Mucin-3
  • Galectins
  • Myeloid Progenitor Cells
  • Myeloid Leukemia
  • Drive
  77 Citations (Scopus)

• CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: Redefinition of murine common myeloid progenitor

  Miyawaki, K., Arinobu, Y., Iwasaki, H., Kohno, K., Tsuzuki, H., Iino, T., Shima, T., Kikushige, Y., Takenaka, K., Miyamoto, T. & Akashi, K., Mar 1 2015, In: STEM CELLS. 33, 3, p. 976-987 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Myeloid Progenitor Cells
  • Hematopoiesis
  • Cytidine Monophosphate
  • Myelopoiesis
  • Population
  28 Citations (Scopus)

• Characteristics of patients with development of large granular lymphocyte expansion among dasatinib-treated patients with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic stem cell transplantation

  Ito, Y., Miyamoto, T., Kamimura, T., Aoki, K., Henzan, H., Aoki, T., Shiratsuchi, M., Kato, K., Nagafuji, K., Ogawa, R., Eto, T., Iwasaki, H. & Akashi, K., Mar 1 2015, In: Clinical Lymphoma, Myeloma and Leukemia. 15, 3, p. e47-e54

  Research output: Contribution to journal › Article › peer-review

  • Dasatinib
  • Philadelphia Chromosome
  • Allogeneic Cells
  • Stem Cell Transplantation
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  6 Citations (Scopus)

• Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study

  Suehiro, Y., Hasegawa, A., Iino, T., Sasada, A., Watanabe, N., Matsuoka, M., Takamori, A., Tanosaki, R., Utsunomiya, A., Choi, I., Fukuda, T., Miura, O., Takaishi, S., Teshima, T., Akashi, K., Kannagi, M., Uike, N. & Okamura, J., May 1 2015, In: British Journal of Haematology. 169, 3, p. 356-367 12 p.

  Research output: Contribution to journal › Article › peer-review

  • leucyl-leucyl-phenylalanyl-glycyl-tyrosyl-prolyl-valyl-tyrosyl-valine
  • Adult T Cell Leukemia Lymphoma
  • Dendritic Cells
  • Cytotoxic T-Lymphocytes
  • Vaccines
  54 Citations (Scopus)

• Decreased secretion of Paneth cell α-defensins in graft-versus-host disease

  Eriguchi, Y., Nakamura, K., Hashimoto, D., Shimoda, S., Shimono, N., Akashi, K., Ayabe, T. & Teshima, T., Oct 2015, In: Transplant Infectious Disease. 17, 5, p. 702-706 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Paneth Cells
  • Defensins
  • Graft vs Host Disease
  • cryptdin
  • Dysbiosis
  26 Citations (Scopus)

• Dietary patterns and the risk of systemic lupus erythematosus in a Japanese population: The Kyushu Sapporo SLE (KYSS) Study

  the Kyushu Sapporo SLE (KYSS) Study Group, Jan 1 2015, In: International Medical Journal. 22, 3, p. 110-115 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Systemic Lupus Erythematosus
  • Dairy Products
  • Population
  • Vegetable Products
  • Meat Products
  1 Citation (Scopus)

• Downregulation of CXCR4 in metastasized breast cancer cells and implication in their dormancy

  Nobutani, K., Shimono, Y., Mizutani, K., Ueda, Y., Suzuki, T., Kitayama, M., Minami, A., Momose, K., Miyawaki, K., Akashi, K., Azuma, T. & Takai, Y., Jun 17 2015, In: PloS one. 10, 6, 0130032.

  Research output: Contribution to journal › Article › peer-review

  • breast neoplasms
  • dormancy
  • Cells
  • neoplasm cells
  • Down-Regulation
  20 Citations (Scopus)

• Effects of conditioning intensity in allogeneic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia

  Takashima, S., Miyamoto, T., Kamimura, T., Yoshimoto, G., Yoshida, S., Henzan, H., Takase, K., Kato, K., Ito, Y., Ohno, Y., Nagafuji, K., Eto, T., Teshima, T. & Akashi, K., Dec 1 2015, In: International journal of hematology. 102, 6, p. 689-696 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Philadelphia Chromosome
  • Allogeneic Cells
  • Stem Cell Transplantation
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Survival Rate
  2 Citations (Scopus)

• Efficacy and safety of ruxolitinib in Asian patients with myelofibrosis

  Jung, C. W., Shih, L. Y., Xiao, Z., Jie, J., Hou, H. A., Du, X., Wang, M. C., Park, S., Eom, K. S., Oritani, K., Okamoto, S., Tauchi, T., Kim, J. S., Zhou, D., Saito, S., Li, J., Handa, H., Jianyong, L., Ohishi, K., Hou, M. & 8 others, Depei, W., Takenaka, K., Liu, T., Hu, Y., Amagasaki, T., Ito, K., Gopalakrishna, P. & Akashi, K., Jul 1 2015, In: Leukemia and Lymphoma. 56, 7, p. 2067-2074 8 p.

  Research output: Contribution to journal › Article › peer-review

  • INCB018424
  • Primary Myelofibrosis
  • Safety
  • Splenomegaly
  • Janus Kinase 1
  18 Citations (Scopus)

• Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells

  Aikawa, Y., Yamagata, K., Katsumoto, T., Shima, Y., Shino, M., Stanley, E. R., Cleary, M. L., Akashi, K., Tenen, D. G. & Kitabayashi, I., Mar 1 2015, In: Cancer Science. 106, 3, p. 227-236 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Leukemia
  • Stem Cells
  • Acute Myeloid Leukemia
  • Maintenance
  • Myeloid-Lymphoid Leukemia Protein
  12 Citations (Scopus)

• Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma

  Kiyasu, J., Miyoshi, H., Hirata, A., Arakawa, F., Ichikawa, A., Niino, D., Sugita, Y., Yufu, Y., Choi, I., Abe, Y., Uike, N., Nagafuji, K., Okamura, T., Akashi, K., Takayanagi, R., Shiratsuchi, M. & Ohshima, K., Nov 5 2015, In: Blood. 126, 19, p. 2193-2201 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell death
  • Lymphoma, Large B-Cell, Diffuse
  • Cells
  • Cell Death
  • Ligands
  243 Citations (Scopus)

• Factors prognostic of eligibility for allogeneic HCT among older patients with AML-CR1 and adverse- or intermediate-risk cytogenetics

  Yamasaki, S., Yoshimoto, G., Ogawa, R., Aoki, K., Higuchi, M., Harada, N., Arima, F., Kondo, S., Matubara, F., Takahashi, T., Uike, N., Miyamoto, T., Okamura, S. & Akashi, K., Jul 18 2015, In: Annals of Hematology. 94, 7, p. 1159-1165 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cytogenetics
  • Acute Myeloid Leukemia
  • Cell Transplantation
  • Allogeneic Cells
  • Karnofsky Performance Status
  3 Citations (Scopus)

• HLA-Haploidentical Peripheral Blood Stem Cell Transplantation with Post-Transplant Cyclophosphamide after Busulfan-Containing Reduced-Intensity Conditioning

  on behalf of the Japan Study Group for Cell Therapy and Transplantation, Sep 1 2015, In: Biology of Blood and Marrow Transplantation. 21, 9, p. 1646-1652 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Peripheral Blood Stem Cell Transplantation
  • Busulfan
  • Cyclophosphamide
  • Hematopoietic Stem Cell Transplantation
  • Transplants
  46 Citations (Scopus)

• Identification and biology of CML stem cells

  Iwasaki, H. & Akashi, K., Jan 1 2015, Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia. Springer Japan, p. 1-10 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Myeloid Progenitor Cells
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive
  • Hematopoietic Stem Cells
  • Protein-Tyrosine Kinases
  • Stem Cell Niche
  1 Citation (Scopus)

• Increased CD226 expression on CD8⁺ T cells is associated with upregulated cytokine production and endothelial cell injury in patients with systemic sclerosis

  Ayano, M., Tsukamoto, H., Kohno, K., Ueda, N., Tanaka, A., Mitoma, H., Akahoshi, M., Arinobu, Y., Niiro, H., Horiuchi, T. & Akashi, K., Aug 1 2015, In: Journal of Immunology. 195, 3, p. 892-900 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Systemic Scleroderma
  • Endothelial Cells
  • Cytokines
  • T-Lymphocytes
  • Wounds and Injuries
  23 Citations (Scopus)

• Increased Syk phosphorylation leads to overexpression of TRAF6 in peripheral B cells of patients with systemic lupus erythematosus

  Iwata, S., Yamaoka, K., Niiro, H., Jabbarzadeh-Tabrizi, S., Wang, S. P., Kondo, M., Yoshikawa, M., Akashi, K. & Tanaka, Y., Jun 3 2015, In: Lupus. 24, 7, p. 695-704 10 p.

  Research output: Contribution to journal › Article › peer-review

  • TNF Receptor-Associated Factor 6
  • Systemic Lupus Erythematosus
  • B-Lymphocytes
  • Phosphorylation
  • 2-(7-(3,4-dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide
  13 Citations (Scopus)

• M2 macrophages enhance pathological neovascularization in the mouse model of oxygen-induced retinopathy

  Zhou, Y., Yoshida, S., Nakao, S., Yoshimura, T., Kobayashi, Y., Nakama, T., Kubo, Y., Miyawaki, K., Yamaguchi, M., Ishikawa, K., Oshima, Y., Akashi, K. & Ishibashi, T., 2015, In: Investigative Ophthalmology and Visual Science. 56, 8, p. 4767-4777 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Pathologic Neovascularization
  • Oxygen
  • Macrophages
  • Retinal Neovascularization
  • Endothelial Cells
  32 Citations (Scopus)

• Microarray analysis of gene expression in fibrovascular membranes excised from patients with proliferative diabetic retinopathy

  Ishikawa, K., Yoshida, S., Kobayashi, Y., Zhou, Y., Nakama, T., Nakao, S., Sassa, Y., Oshima, Y., Niiro, H., Akashi, K., Kono, T. & Ishibashi, T., 2015, In: Investigative Ophthalmology and Visual Science. 56, 2, p. 932-946 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Diabetic Retinopathy
  • Microarray Analysis
  • Gene Expression
  • Membranes
  • Genes
  29 Citations (Scopus)

• Natural killer cells regulate T cell immune responses in primary biliary cirrhosis

  Shimoda, S., Hisamoto, S., Harada, K., Iwasaka, S., Chong, Y., Nakamura, M., Bekki, Y., Yoshizumi, T., Shirabe, K., Ikegami, T., Maehara, Y., He, X. S., Gershwin, M. E. & Akashi, K., Dec 1 2015, In: Hepatology. 62, 6, p. 1817-1827 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Biliary Liver Cirrhosis
  • Natural Killer Cells
  • Epithelial Cells
  • T-Lymphocytes
  • Interferons
  39 Citations (Scopus)

• Preserved in vivo reconstitution ability of PBSCs cryopreserved for a decade at -80 °c

  Shima, T., Iwasaki, H., Yamauchi, T., Kadowaki, M., Kiyosuke, M., Mochimaru, T., Takenaka, K., Miyamoto, T., Akashi, K. & Teshima, T., Sep 4 2015, In: Bone Marrow Transplantation. 50, 9, p. 1195-1200 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Cryopreservation
  • Homologous Transplantation
  • Autologous Transplantation
  • Freezing
  • Nitrogen
  3 Citations (Scopus)