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  • Koichi Akashi

[A case report of malignant lymphoma receiving infliximab therapy with Behçet's disease].

Sonoda, K. H., Fukuhara, T., Yoshikawa, H., Takeda, A., Yoshimura, T., Akahoshi, M., Kusumoto, H., Kohno, K., Kato, K., Akashi, K., Kohashi, K., Aijima, S., Namba, K. & Ishibashi, T., May 2014, In : Nippon Ganka Gakkai zasshi. 118, 5, p. 440-445 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

[Clinical aspects of primary myelofibrosis in Japan].

Shimoda, K., Takenaka, K., Kitanaka, A. & Akashi, K., 2014, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 55, 3, p. 289-294 6 p.

Research output: Contribution to journalReview article

[Clinical outcomes of allogeneic hematopoietic stem cell transplantation for adult primary myelofibrosis: retrospective analysis by Fukuoka BMT group].

Kamimura, T., Yong, C., Ito, Y., Henzan, H., Miyamoto, T., Ohno, Y., Eto, T., Takenaka, K. & Akashi, K., Mar 2012, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 53, 3, p. 323-328 6 p.

Research output: Contribution to journalReview article

[Diagnostic usefulness of FDG-PET/CT in multiple primary osseous Hodgkin lymphoma].

Kamezaki, K., Harada, Y., Shimono, N., Ohshima, K. & Akashi, K., Dec 2012, In : Unknown Journal. 53, 12, p. 2003-2007 5 p.

Research output: Contribution to journalArticle

[Effect of bortezomib-based induction therapy on the peripheral blood stem cell harvest in multiple myeloma].

Muta, T., Miyamoto, T., Fujisaki, T., Ohno, Y., Kamimura, T., Henzan, T., Kato, K., Takenaka, K., Iwasaki, H., Eto, T., Takamatsu, Y., Teshima, T., Akashi, K. & Fukuoka Blood, B., Jan 1 2013, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 54, 1, p. 109-116 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

[Leukemia stem cells: current understanding and future directions].

Takenaka, K. & Akashi, K., Apr 2012, In : Nihon rinsho. Japanese journal of clinical medicine. 70 Suppl 2, p. 139-145 7 p.

Research output: Contribution to journalArticle

[Myeloid lineage commitment from the hematopoietic stem cell].

Arinobu, Y. & Akashi, K., Jul 2011, In : Japanese Journal of Allergology. 60, 7, p. 817-822 6 p.

Research output: Contribution to journalReview article

[New approaches to target leukemia stem cells]

Takenaka, K. & Akashi, K., Jun 1 2014, In : Nihon rinsho. Japanese journal of clinical medicine. 72, 6, p. 1018-1025 8 p.

Research output: Contribution to journalArticle

[Specific surface markers of AML-leukemic stem cells].

Kikushige, Y., Miyamoto, T. & Akashi, K., Jul 1 2011, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 52, 7, p. 531-534 4 p.

Research output: Contribution to journalReview article

A co-localization model of paired ChIP-seq data using a large ENCODE data set enables comparison of multiple samples

Maehara, K., Odawara, J., Harada, A., Yoshimi, T., Nagao, K., Obuse, C., Akashi, K., Tachibana, T., Sakata, T. & Ohkawa, Y., Jan 1 2013, In : Nucleic acids research. 41, 1, p. 54-62 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Acquired initiating mutations in early hematopoietic cells of CLL patients

Damm, F., Mylonas, E., Cosson, A., Yoshida, K., Della Valle, V., Mouly, E., Diop, M., Scourzic, L., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Kikushige, Y., Davi, F., Lambert, J., Gautheret, D., Merle-Béral, H., Sutton, L., Dessen, P., Solary, E. & 7 others, Akashi, K., Vainchenker, W., Mercher, T., Droin, N., Ogawa, S., Nguyen-Khac, F. & Bernard, O. A., Sep 2014, In : Cancer Discovery. 4, 9, p. 1088-1101 14 p.

Research output: Contribution to journalArticle

131 Citations (Scopus)

Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody

Yamaguchi, K., Mishima, K., Ohmura, H., Hanamura, F., Ito, M., Nakano, M., Tsuchihashi, K., Ota, S. I., Wada, N., Uchi, H., Ariyama, H., Kusaba, H., Niiro, H., Akashi, K. & Baba, E., Oct 2018, In : Cancer Science. 109, 10, p. 3032-3042 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Acute and Chronic Effects of Cancer Drugs on the Cardiovascular System

Moriyama, S., Fukata, M., Kusaba, H., Maruyama, T. & Akashi, K., Apr 2020, In : Heart Failure Clinics. 16, 2, p. 231-241 11 p.

Research output: Contribution to journalReview article

Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

Tominaga, K., Shimamura, T., Kimura, N., Murayama, T., Matsubara, D., Kanauchi, H., Niida, A., Shimizu, S., Nishioka, K., Tsuji, E. I., Yano, M., Sugano, S., Shimono, Y., Ishii, H., Saya, H., Mori, M., Akashi, K., Tada, K. I., Ogawa, T., Tojo, A. & 2 others, Miyano, S. & Gotoh, N., Mar 2 2017, In : Oncogene. 36, 9, p. 1276-1286 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
7 Citations (Scopus)

Adult T-Cell Leukemia After Deceased Donor Liver Transplantation for Acute Liver Failure: A Case Report

Motomura, T., Yoshizumi, T., Kosai-Fujimoto, Y., Mano, Y., Toshima, T., Takeishi, K., Itoh, S., Harada, N., Ikegami, T., Soejima, Y., Yoshimoto, G., Akashi, K. & Mori, M., Jul 1 2019, In : Transplantation Proceedings. 51, 6, p. 1978-1981 4 p.

Research output: Contribution to journalArticle

Advances in therapies for acute promyelocytic leukemia

Kamimura, T., Miyamoto, T., Harada, M. & Akashi, K., Nov 1 2011, In : Cancer Science. 102, 11, p. 1929-1937 9 p.

Research output: Contribution to journalReview article

38 Citations (Scopus)

Allogeneic hematopoietic stem cell transplantation for adult T-cell leukemia-lymphoma with special emphasis on preconditioning regimen: A nationwide retrospective study

Ishida, T., Hishizawa, M., Kato, K., Tanosaki, R., Fukuda, T., Taniguchi, S., Eto, T., Takatsuka, Y., Miyazaki, Y., Moriuchi, Y., Hidaka, M., Akashi, K., Uike, N., Sakamaki, H., Morishima, Y., Suzuki, R., Nishiyama, T. & Utsunomiya, A., Aug 23 2012, In : Blood. 120, 8, p. 1734-1741 8 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Amplification of Toll-like receptor-mediated signaling through spleen tyrosine kinase in human B-cell activation

Iwata, S., Yamaoka, K., Niiro, H., Nakano, K., Wang, S. P., Akashi, K. & Tanaka, Y., Jun 2012, In : Journal of Allergy and Clinical Immunology. 129, 6, p. 1594-1601.e2

Research output: Contribution to journalArticle

21 Citations (Scopus)

Amrubicin monotherapy for patients with extrapulmonary neuroendocrine carcinoma after platinum-based chemotherapy

Nio, K., Arita, S., Isobe, T., Kusaba, H., Kohashi, K., Kajitani, T., Tamura, S., Hirano, G., Mitsugi, K., Makiyama, A., Esaki, T., Ariyama, H., Oda, Y., Akashi, K. & Baba, E., Apr 2015, In : Cancer chemotherapy and pharmacology. 75, 4, p. 829-835 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A multinational, open-label, phase 2 study of ruxolitinib in Asian patients with myelofibrosis: Japanese subset analysis

Oritani, K., Okamoto, S., Tauchi, T., Saito, S., Ohishi, K., Handa, H., Takenaka, K., Gopalakrishna, P., Amagasaki, T., Ito, K. & Akashi, K., Mar 6 2015, In : International journal of hematology. 101, 3, p. 295-304 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Analysis of adverse events of bevacizumab-containing systemic chemotherapy for metastatic colorectal cancer in Japan

Isobe, T., Uchino, K., Makiyama, C., Ariyama, H., Arita, S., Tamura, S., Komoda, M., Kusaba, H., Shirakawa, T., Esaki, T., Mitsugi, K., Takaishi, S., Akashi, K. & Baba, E., Apr 1 2014, In : Anticancer research. 34, 4, p. 2035-2040 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Analysis of GNA13 Protein in Follicular Lymphoma and its Association with Poor Prognosis

Shimono, J., Miyoshi, H., Yoshida, N., Kato, T., Sato, K., Sugio, T., Miyawaki, K., Kurita, D., Sasaki, Y., Kawamoto, K., Imaizumi, Y., Kato, K., Nagafuji, K., Akashi, K., Seto, M., Teshima, T. & Ohshima, K., Nov 1 2018, In : American Journal of Surgical Pathology. 42, 11, p. 1466-1471 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Analysis of immune reconstitution after autologous CD34 + stem/progenitor cell transplantation for systemic sclerosis: Predominant reconstitution of Th1 CD4 + t cells

Tsukamoto, H., Nagafuji, K., Horiuchi, T., Mitoma, H., Niiro, H., Arinobu, Y., Inoue, Y., To, K., Miyamoto, T., Iwasaki, H., Teshima, T., Harada, M. & Akashi, K., May 1 2011, In : Rheumatology. 50, 5, p. 944-952 9 p., keq414.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Analysis of the variable factors influencing tacrolimus blood concentration during the switch from continuous intravenous infusion to oral administration after allogeneic hematopoietic stem cell transplantation

Suetsugu, K., Ikesue, H., Miyamoto, T., Shiratsuchi, M., Yamamoto-Taguchi, N., Tsuchiya, Y., Matsukawa, K., Uchida, M., Watanabe, H., Akashi, K. & Masuda, S., Mar 1 2017, In : International journal of hematology. 105, 3, p. 361-368 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A novel filtration method for cord blood processing using a polyester fabric filter

Shima, T., Forraz, N., Sato, N., Yamauchi, T., Iwasaki, H., Takenaka, K., Akashi, K., Mcguckin, C. & Teshima, T., Aug 1 2013, In : International Journal of Laboratory Hematology. 35, 4, p. 436-446 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A novel scoring system based on common laboratory tests predicts the efficacy of TNF-inhibitor and IL-6 targeted therapy in patients with rheumatoid arthritis: a retrospective, multicenter observational study

Nakagawa, J., Koyama, Y., Kawakami, A., Ueki, Y., Tsukamoto, H., Horiuchi, T., Nagano, S., Uchino, A., Ota, T., Akahoshi, M. & Akashi, K., Aug 11 2017, In : Arthritis research & therapy. 19, 1, 1 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Antibiotic Rotation for Febrile Neutropenic Patients with Hematological Malignancies: Clinical Significance of Antibiotic Heterogeneity

Chong, Y., Shimoda, S., Yakushiji, H., Ito, Y., Miyamoto, T., Kamimura, T., Shimono, N. & Akashi, K., Jan 29 2013, In : PloS one. 8, 1, e54190.

Research output: Contribution to journalArticle

16 Citations (Scopus)
4 Citations (Scopus)

Antiemetic effectiveness and safety of aprepitant in patients with hematologic malignancy receiving multiday chemotherapy

Uchida, M., Ikesue, H., Kato, K., Ichinose, K., Hiraiwa, H., Sakurai, A., Takenaka, K., Iwasaki, H., Miyamoto, T., Teshima, T., Egashira, N., Akashi, K. & Oishi, R., Feb 15 2013, In : American Journal of Health-System Pharmacy. 70, 4, p. 343-349 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Anti-GPRC5D/CD3 bispecific T-cell-redirecting antibody for the treatment of multiple myeloma

Kodama, T., Kochi, Y., Nakai, W., Mizuno, H., Baba, T., Habu, K., Sawada, N., Tsunoda, H., Shima, T., Miyawaki, K., Kikushige, Y., Mori, Y., Miyamoto, T., Maeda, T. & Akashi, K., Jan 1 2019, In : Molecular Cancer Therapeutics. 18, 9, p. 1555-1564 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy

Kumagai, H., Kusaba, H., Yamanaka, T., Nio, K., Inadomi, K., Takayoshi, K., Ito, M., Tamura, S., Makiyama, A., Makiyama, C., Hirano, G., Shibata, Y., Shirakawa, T., Mitsugi, K., Ariyama, H., Esaki, T., Akashi, K. & Baba, E., Jun 1 2018, In : Medicine (United States). 97, 25, e11042.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A phase II study of lenalidomide consolidation and maintenance therapy after autologous PBSCT in patients with multiple myeloma

on behalf of the Japan Study Group for Cell Therapy and Transplantation (JSCT), Jan 22 2019, In : International journal of hematology. 109, 1, p. 107-114 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A retrospective analysis for thromboembolic events associated with multikinase inhibitors

Nio, K., Tsuchihashi, K., Kusaba, H., Yoshihiro, T., Arita, S., Ariyama, H., Arita, T., Odashiro, K., Akashi, K. & Baba, E., Oct 1 2017, In : Annals of oncology : official journal of the European Society for Medical Oncology. 28, p. ix77

Research output: Contribution to journalArticle

Open Access

Ascites retention during mogamulizumab treatment in a patient with adult T-cell leukemia/lymphoma

Shima, T., Kamezaki, K., Higashioka, K., Takashima, S., Yoshimoto, G., Kato, K., Muta, T., Takenaka, K., Iwasaki, H., Miyamoto, T. & Akashi, K., Jan 1 2016, In : Internal Medicine. 55, 13, p. 1793-1796 4 p.

Research output: Contribution to journalArticle

Assessing the safety and efficacy of ruxolitinib in a multicenter, open-label study in Japanese patients with myelofibrosis

Komatsu, N., Kirito, K., Shimoda, K., Ishikawa, T., Ohishi, K., Ohyashiki, K., Takahashi, N., Okada, H., Amagasaki, T., Yonezu, T. & Akashi, K., Mar 1 2017, In : International journal of hematology. 105, 3, p. 309-317 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Assessment of erythrocyte deformability in an obese case of chronic thromboembolic pulmonary hypertension

Yoda, S., Yokoyama, T., Fukata, M., Arita, T., Odashiro, K., Maruyama, T. & Akashi, K., Jan 1 2017, In : Journal of Biorheology. 31, 2, p. 57-60 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression

Kikushige, Y., Miyamoto, T., Yuda, J., Jabbarzadeh-Tabrizi, S., Shima, T., Takayanagi, S. I., Niiro, H., Yurino, A., Miyawaki, K., Takenaka, K., Iwasaki, H. & Akashi, K., Sep 3 2015, In : Cell stem cell. 17, 3, p. 341-352 12 p., 1815.

Research output: Contribution to journalArticle

55 Citations (Scopus)

A Transcriptional Switch Point during Hematopoietic Stem and Progenitor Cell Ontogeny

Sugiyama, D., Joshi, A., Kulkeaw, K., Tan, K. S., Yokoo-Inoue, T., Mizuochi-Yanagi, C., Yasuda, K., Doi, A., Iino, T., Itoh, M., Nagao-Sato, S., Tani, K., Akashi, K., Hayashizaki, Y., Suzuki, H., Kawaji, H., Carninci, P. & Forrest, A. R. R., Mar 1 2017, In : Stem cells and development. 26, 5, p. 314-327 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Atrial fibrillation observed in a patient with esophageal cancer treated with fluorouracil

Moriyama, S., Yokoyama, T., Irie, K., Ito, M., Tsuchihashi, K., Fukata, M., Kusaba, H., Maruyama, T. & Akashi, K., Nov 2019, In : Journal of Cardiology Cases. 20, 5, p. 183-186 4 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Autologous peripheral blood stem cell transplantation with granulocyte colony-stimulating factor combined conditioning regimen as a postremission therapy for acute myelogenous leukemia in first complete remission

Eto, T., Takase, K., Miyamoto, T., Ohno, Y., Kamimura, T., Nagafuji, K., Takamatsu, Y., Teshima, T., Gondo, H., Taniguchi, S., Akashi, K. & Harada, M., Aug 1 2013, In : International journal of hematology. 98, 2, p. 186-196 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Bi-cytopenia possibly induced by anti-PD-1 antibody for primary malignant melanoma of the esophagus A case report

Inadomi, K., Kumagai, H., Arita, S., Tsuruta, N., Takayoshi, K., Mishima, K., Ota, S. I., Tanaka, M., Okumura, Y., Sagara, K., Nio, K., Nakano, M., Uchi, H., Yamamoto, H., Ariyama, H., Kusaba, H., Niiro, H., Oda, Y., Akashi, K. & Baba, E., Jul 26 2016, In : Medicine (United States). 95, 29, e4283.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Bortezomib-based strategy with autologous stem cell transplantation for newly diagnosed multiple myeloma: a phase II study by the Japan Study Group for Cell Therapy and Transplantation (JSCT-MM12)

Sunami, K., Matsumoto, M., Fuchida, S. I., Omoto, E., Takamatsu, H., Adachi, Y., Choi, I., Fujishima, N., Kiguchi, T., Miyamoto, T., Maeda, A., Suzumiya, J., Yamamura, R., Nagafuji, K., Nakazato, T., Kuroda, Y., Yujiri, T., Takamatsu, Y., Harada, M. & Akashi, K., Jan 1 2019, In : International Journal of Clinical Oncology.

Research output: Contribution to journalArticle

C/EBPΑ is required for development of dendritic cell progenitors

Welner, R. S., Bararia, D., Amabile, G., Czibere, A., Benoukraf, T., Bach, C., Wansa, K. D. S. A., Ye, M., Zhang, H., Iino, T., Hetherington, C. J., Akashi, K. & Tenen, D. G., May 16 2013, In : Blood. 121, 20, p. 4073-4081 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)