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  • Koichi Akashi

Helper T cell-dominant tertiary lymphoid structures are associated with disease relapse of advanced colorectal cancer

Yamaguchi, K., Ito, M., Ohmura, H., Hanamura, F., Nakano, M., Tsuchihashi, K., Nagai, S., Ariyama, H., Kusaba, H., Yamamoto, H., Oda, Y., Nakamura, M., Akashi, K. & Baba, E., Jan 1 2020, In : OncoImmunology. 9, 1, 1724763.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack

Espinoza, J. L., Elbadry, M. I., Chonabayashi, K., Yoshida, Y., Katagiri, T., Harada, K., Nakagawa, N., Zaimoku, Y., Imi, T., Takamatsu, H., Ozawa, T., Maruyama, H., Hassanein, H. A., Noreldin, A. K. A., Takenaka, K., Akashi, K., Hamana, H., Kishi, H., Akatsuka, Y. & Nakao, S., Feb 27 2018, In : Blood Advances. 2, 4, p. 390-400 11 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Hepatitis C virus infection is an independent prognostic factor in follicular lymphoma

Shimono, J., Miyoshi, H., Kato, T., Sugio, T., Miyawaki, K., Kamimura, T., Miyagishima, T., Eto, T., Imaizumi, Y., Kato, K., Nagafuji, K., Akashi, K., Seto, M., Teshima, T. & Ohshima, K., Jan 1 2018, In : Oncotarget. 9, 2, p. 1717-1725 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Hereditary angioedema in Japan: Genetic analysis of 13 unrelated cases

Yamamoto, T., Horiuchi, T., Miyahara, H., Yoshizawa, S., Maehara, J., Shono, E., Takamura, K., MacHida, H., Tsujioka, K., Kaneko, T., Uemura, N., Suzawa, K., Inagaki, N., Umegaki, N., Kasamatsu, Y., Hara, A., Arinobu, Y., Inoue, Y., Niiro, H., Kashiwagai, Y. & 4 others, Harashima, S. I., Tahira, T., Tsukamoto, H. & Akashi, K., Mar 2012, In : American Journal of the Medical Sciences. 343, 3, p. 210-214 5 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Higher incidence of injection site reactions after subcutaneous bortezomib administration on the thigh compared with the abdomen

Kamimura, T., Miyamoto, T., Yokota, N., Takashima, S., Chong, Y., Ito, Y. & Akashi, K., Feb 1 2013, In : European Journal of Haematology. 90, 2, p. 157-161 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

High incidence and severity of injection site reactions in the first cycle compared with subsequent cycles of subcutaneous bortezomib

Kamimura, T., Miyamoto, T., Yokota, N., Aoki, T., Ito, Y. & Akashi, K., Dec 1 2013, In : International journal of hematology. 98, 6, p. 694-701 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

HLA-Haploidentical Peripheral Blood Stem Cell Transplantation with Post-Transplant Cyclophosphamide after Busulfan-Containing Reduced-Intensity Conditioning

on behalf of the Japan Study Group for Cell Therapy and Transplantation, Sep 1 2015, In : Biology of Blood and Marrow Transplantation. 21, 9, p. 1646-1652 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Homeostatic milieu induces production of deoxyribonuclease 1-like 3 from myeloid cells

Inokuchi, S., Mitoma, H., Kawano, S., Nakano, S., Ayano, M., Kimoto, Y., Akahoshi, M., Arinobu, Y., Tsukamoto, H., Akashi, K., Horiuchi, T. & Niiro, H., Apr 15 2020, In : Journal of Immunology. 204, 8, p. 2088-2097 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells

Uchino, K., Hirano, G., Hirahashi, M., Isobe, T., Shirakawa, T., Kusaba, H., Baba, E., Tsuneyoshi, M. & Akashi, K., Sep 10 2012, In : Experimental Cell Research. 318, 15, p. 1799-1807 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Human STEAP3 maintains tumor growth under hypoferric condition

Isobe, T., Baba, E., Arita, S., Komoda, M., Tamura, S., Shirakawa, T., Ariyama, H., Takaishi, S., Kusaba, H., Ueki, T. & Akashi, K., Nov 1 2011, In : Experimental Cell Research. 317, 18, p. 2582-2591 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Hydrophobic bile acids suppress expression of AE2 in biliary epithelial cells and induce bile duct inflammation in primary biliary cholangitis

Hisamoto, S., Shimoda, S., Harada, K., Iwasaka, S., Onohara, S., Chong, Y., Nakamura, M., Bekki, Y., Yoshizumi, T., Ikegami, T., Maehara, Y., He, X. S., Gershwin, M. E. & Akashi, K., Dec 1 2016, In : Journal of Autoimmunity. 75, p. 150-160 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Hypoalbuminemia for the prediction of venous thromboembolism and treatment of direct oral anticoagulants in metastatic gastric cancer patients

Takayoshi, K., Kusaba, H., Aikawa, T., Koreishi, S., Sagara, K., Nakano, M., Komoda, M., Kono, M., Fukata, M., Arita, T., Esaki, T., Akashi, K. & Baba, E., Sep 5 2019, In : Gastric Cancer. 22, 5, p. 988-998 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Identification and biology of CML stem cells

Iwasaki, H. & Akashi, K., Jan 1 2015, Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia. Springer Japan, p. 1-10 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Identification of a Human Clonogenic Progenitor with Strict Monocyte Differentiation Potential: A Counterpart of Mouse cMoPs

Kawamura, S., Onai, N., Miya, F., Sato, T., Tsunoda, T., Kurabayashi, K., Yotsumoto, S., Kuroda, S., Takenaka, K., Akashi, K. & Ohteki, T., May 16 2017, In : Immunity. 46, 5, p. 835-848.e4

Research output: Contribution to journalArticle

27 Citations (Scopus)

Identification of human erythroid lineage-committed progenitors

Mori, Y., Akashi, K. & Weissman, I. L., May 1 2016, In : [Rinsho ketsueki] The Japanese journal of clinical hematology. 57, 5, p. 585-591 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Identification of unipotent megakaryocyte progenitors in human hematopoiesis

Miyawaki, K., Iwasaki, H., Jiromaru, T., Kusumoto, H., Yurino, A., Sugio, T., Uehara, Y., Odawara, J., Daitoku, S., Kunisaki, Y., Mori, Y., Arinobu, Y., Tsuzuki, H., Kikushige, Y., Iino, T., Kato, K., Takenaka, K., Miyamoto, T., Maeda, T. & Akashi, K., Jun 22 2017, In : Blood. 129, 25, p. 3332-3343 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Immunosuppressant therapy successfully improved regorafenib-induced severe hepatic injury in a patient with metastatic gastrointestinal stromal tumor: A case report

Kuwayama, M., Uchino, K., Takayoshi, K., Komoda, M., Kohjima, M., Nakamuta, M., Momosaki, S., Kusaba, H., Akashi, K. & Baba, E., Jan 2016, In : Oncology Letters. 11, 1, p. 85-88 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access
4 Citations (Scopus)

Impaired deformability of erythrocytes in diabetic rat and human: Investigation by the nickel-mesh-filtration technique

Saito, K., Kogawa, Y., Fukata, M., Odashiro, K., Maruyama, T., Akashi, K. & Fujino, T., Dec 1 2011, In : Journal of Biorheology. 25, 1-2, p. 18-26 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Impaired erythrocyte deformability in patients with coronary risk factors: Significance of nonvalvular atrial fibrillation

Odashiro, K., Maruyama, T., Yokoyama, T., Nakamura, H., Fukata, M., Yasuda, S., Saito, K., Fujino, T. & Akashi, K., Oct 1 2013, In : Journal of Atrial Fibrillation. 6, 3, p. 6-12 7 p.

Research output: Contribution to journalArticle

Improvement of diabetic or obese patients' erythrocyte deformability by the program of the brain-oriented obesity control system (BOOCS)

Saito, K., Odashiro, K., Maruyama, T., Akashi, K., Mawatari, S. & Fujino, T., Nov 1 2012, In : Journal of Physiological Sciences. 62, 6, p. 445-451 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Improvement of quality of life and survival using self-expandable metal stent placement for severe malignant stenosis of the gastric body: A case report

Kumagai, H., Nio, K., Shirakawa, T., Uchino, K., Kusaba, H., Isobe, T., Komoda, M., Tamura, S., Maeyama, R., Nagai, E., Akashi, K. & Baba, E., Sep 21 2012, In : Journal of Medical Case Reports. 6, 315.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Increased CD226 expression on CD8+ T cells is associated with upregulated cytokine production and endothelial cell injury in patients with systemic sclerosis

Ayano, M., Tsukamoto, H., Kohno, K., Ueda, N., Tanaka, A., Mitoma, H., Akahoshi, M., Arinobu, Y., Niiro, H., Horiuchi, T. & Akashi, K., Aug 1 2015, In : Journal of Immunology. 195, 3, p. 892-900 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Increased Syk phosphorylation leads to overexpression of TRAF6 in peripheral B cells of patients with systemic lupus erythematosus

Iwata, S., Yamaoka, K., Niiro, H., Jabbarzadeh-Tabrizi, S., Wang, S. P., Kondo, M., Yoshikawa, M., Akashi, K. & Tanaka, Y., Jun 3 2015, In : Lupus. 24, 7, p. 695-704 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Increasing diluent volume decreases bendamustine-induced venous irritation without reducing the therapeutic efficacy

Ishida, S., Morikawa, H., Watanabe, H., Tsuji, T., Sugio, T., Mori, Y., Miyamoto, T., Masuda, S., Akashi, K. & Egashira, N., Mar 1 2020, In : Biological and Pharmaceutical Bulletin. 43, 3, p. 488-492 5 p.

Research output: Contribution to journalArticle

Open Access

Infective endocarditis caused by Listeria monocytogenes forming a pseudotumor

Uehara Yonekawa, A., Iwasaka, S., Nakamura, H., Fukata, M., Kadowaki, M., Uchida, Y., Odashiro, K., Shimoda, S., Shimono, N. & Akashi, K., 2014, In : Internal Medicine. 53, 9, p. 1029-1032 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Influence of common cardiac drugs on gastroesophageal reflux disease: Multicenter questionnaire survey

Nakaji, G., Fujihara, M., Fukata, M., Yasuda, S., Odashiro, K., Maruyama, T. & Akashi, K., Sep 1 2011, In : International Journal of Clinical Pharmacology and Therapeutics. 49, 9, p. 555-563 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Influence of medical history in parents or siblings on the development of systemic lupus erythematosus among Japanese females

Kyushu Sapporo SLE (KYSS) Study Group, Jan 1 2016, In : International Medical Journal. 23, 5, p. 466-469 4 p.

Research output: Contribution to journalArticle

Initial low-dose valganciclovir as a preemptive therapy is effective for cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients

Takenaka, K., Nagafuji, K., Takase, K., Kamimura, T., Mori, Y., Ito, Y., Nishi, Y., Henzan, H., Kato, K., Harada, N., Eto, T., Miyamoto, T., Teshima, T. & Akashi, K., Jul 2012, In : International journal of hematology. 96, 1, p. 94-100 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Injection site reaction after subcutaneous administration of bortezomib in Japanese patients with multiple myeloma

Kamimura, T., Miyamoto, T., Takashima, S., Yokota, N., Chong, Y., Ito, Y. & Akashi, K., Oct 1 2012, In : International journal of hematology. 96, 4, p. 525-527 3 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets

Karube, K., Enjuanes, A., Dlouhy, I., Jares, P., Martin-Garcia, D., Nadeu, F., Ordóñez, G. R., Rovira, J., Clot, G., Royo, C., Navarro, A., Gonzalez-Farre, B., Vaghefi, A., Castellano, G., Rubio-Perez, C., Tamborero, D., Briones, J., Salar, A., Sancho, J. M., Mercadal, S. & 19 others, Gonzalez-Barca, E., Escoda, L., Miyoshi, H., Ohshima, K., Miyawaki, K., Kato, K., Akashi, K., Mozos, A., Colomo, L., Alcoceba, M., Valera, A., Carrió, A., Costa, D., Lopez-Bigas, N., Schmitz, R., Staudt, L. M., Salaverria, I., López-Guillermo, A. & Campo, E., Mar 1 2018, In : Leukemia. 32, 3, p. 675-684 10 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis

Shimoda, S., Harada, K., Niiro, H., Shirabe, K., Taketomi, A., Maehara, Y., Tsuneyama, K., Nakanuma, Y., Leung, P., Ansari, A. A., Gershwin, M. E. & Akashi, K., Apr 1 2011, In : Hepatology. 53, 4, p. 1270-1281 12 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Interstitial pneumonia during bevacizumab-based chemotherapy for colorectal cancer

Tamura, S., Kusaba, H., Kubo, N., Ijichi, K., Tsuchihashi, K., Komoda, M., Uchino, K., Ariyama, H., Akashi, K. & Baba, E., Jan 1 2014, In : Medical Oncology. 31, 3, 856.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis

Mizuochi, C., Fraser, S. T., Biasch, K., Horio, Y., Kikushige, Y., Tani, K., Akashi, K., Tavian, M. & Sugiyama, D., Apr 27 2012, In : PloS one. 7, 4, e35763.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Intraluminal superior vena cava metastasis from adenosquamous carcinoma of the duodenum: A case report

Takayoshi, K., Ariyama, H., Tamura, S., Yoda, S., Arita, T., Yamaguchi, T., Ozono, K., Yamamoto, H., Inadomi, K., Kumagai, H., Tanaka, M., Okumura, Y., Sagara, K., Nio, K., Nakano, M., Arita, S., Kusaba, H., Odashiro, K., Oda, Y., Akashi, K. & 1 others, Baba, E., Jan 2016, In : Oncology Letters. 11, 1, p. 605-609 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin

Hirano, G., Izumi, H., Yasuniwa, Y., Shimajiri, S., Ke-Yong, W., Sasagiri, Y., Kusaba, H., Matsumoto, K., Hasegawa, T., Akimoto, M., Akashi, K. & Kohno, K., Apr 1 2011, In : International journal of oncology. 38, 4, p. 893-902 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Involvement of Syk in pathology of systemic autoimmune disease

Iwata, S., Yamaoka, K., Nakano, K., Wang, S. P., Saito, K., Tanaka, Y., Niiro, H. & Akashi, K., Jan 1 2012, In : Japanese Journal of Clinical Immunology. 35, 1, p. 56-61 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer

Makiyama, A., Arimizu, K., Hirano, G., Makiyama, C., Matsushita, Y., Shirakawa, T., Ohmura, H., Komoda, M., Uchino, K., Inadomi, K., Arita, S., Ariyama, H., Kusaba, H., Shinohara, Y., Kuwayama, M., Kajitani, T., Oda, H., Esaki, T., Akashi, K. & Baba, E., May 1 2018, In : Gastric Cancer. 21, 3, p. 464-472 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Large-scale genome analysis of bovine commensal Escherichia coli reveals that bovine-adapted E. Coli lineages are serving as evolutionary sources of the emergence of human intestinal pathogenic strains

Arimizu, Y., Kirino, Y., Sato, M. P., Uno, K., Sato, T., Gotoh, Y., Auvray, F., Brugere, H., Oswald, E., Mainil, J. G., Anklam, K. S., Döpfer, D., Yoshino, S., Ooka, T., Tanizawa, Y., Nakamura, Y., Iguchi, A., Morita-Ishihara, T., Ohnishi, M., Akashi, K. & 2 others, Hayashi, T. & Ogura, Y., 2019, In : Genome Research. 29, 9, p. 1495-1505 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Light chain deposition disease in an older adult patient successfully treated with long-term administration of bortezomib, melphalan and prednisone

Hiyamuta, H., Yamada, S., Matsukuma, Y., Tsuchimoto, A., Nakano, T., Taniguchi, M., Masutani, K., Yoshimoto, G., Muta, T., Akashi, K., Kitazono, T. & Tsuruya, K., Jan 1 2016, In : Internal Medicine. 55, 10, p. 1319-1325 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Lingual alveolar soft part sarcoma responsive to pazopanib: A case report

Yoshihiro, T., Tsuchihashi, K., Nio, K., Arita, S., Nakano, T., Yasumatsu, R., Jiroumaru, R., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Nov 2017, In : Medicine (United States). 96, 44, e8470.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Long-term remission after high-dose chemotherapy followed by auto-SCT as consolidation for intravascular large B-cell lymphoma

Kato, K., Ohno, Y., Kamimura, T., Kusumoto, H., Tochigi, T., Jinnouchi, F., Kohno, K., Kuriyama, T., Henzan, H., Takase, K., Kawano, I., Kadowaki, M., Nawata, R., Muta, T., Eto, T., Iawasaki, H., Ohshima, K., Miyamoto, T. & Akashi, K., Dec 11 2014, In : Bone Marrow Transplantation. 49, 12, p. 1543-1544 2 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Low incidence of adenovirus hemorrhagic cystitis following autologous hematopoietic stem cell transplantation in the rituximab era

Mori, Y., Miyamoto, T., Kamezaki, K., Kato, K., Kikushige, Y., Takashima, S., Urata, S., Shimoda, S., Shimono, N., Takenaka, K., Iwasaki, H., Nagafuji, K., Teshima, T. & Akashi, K., Aug 1 2012, In : American Journal of Hematology. 87, 8, p. 828-830 3 p.

Research output: Contribution to journalLetter

6 Citations (Scopus)

M2 macrophages enhance pathological neovascularization in the mouse model of oxygen-induced retinopathy

Zhou, Y., Yoshida, S., Nakao, S., Yoshimura, T., Kobayashi, Y., Nakama, T., Kubo, Y., Miyawaki, K., Yamaguchi, M., Ishikawa, K., Oshima, Y., Akashi, K. & Ishibashi, T., Jan 1 2015, In : Investigative Ophthalmology and Visual Science. 56, 8, p. 4767-4777 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Manifestation of J wave induced by acetylcholine applied for a coronary spasm provocation test in a patient with aborted sudden cardiac death

Kodama, H., Fujita, K., Moriyama, S., Irie, K., Noda, H., Yokoyama, T., Fukata, M., Arita, T., Odashiro, K., Maruyama, T. & Akashi, K., Jun 2017, In : journal of arrhythmia. 33, 3, p. 234-236 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Measurable residual disease after the first consolidation predicts the outcomes of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy

for the Fukuoka Blood & Marrow Transplantation Group (FBMTG), Jan 1 2020, (Accepted/In press) In : International journal of hematology.

Research output: Contribution to journalArticle

Metastatic esophageal cancer presenting as shock by injury of vagus nerve mimicking baroreceptor reflex: A case report

Tsuchihashi, K., Yoshihiro, T., Aikawa, T., Nio, K., Takayoshi, K., Yokoyama, T., Fukata, M., Arita, S., Ariyama, H., Shimizu, Y., Yoshida, Y., Torisu, T., Esaki, M., Odashiro, K., Kusaba, H., Akashi, K. & Baba, E., Dec 1 2017, In : Medicine (United States). 96, 49, e8987.

Research output: Contribution to journalArticle

Metastatic esophageal carcinosarcoma comprising neuroendocrine carcinoma, squamous cell carcinoma, and sarcoma A case report

Tsuchihashi, K., Arita, S., Fujiwara, M., Iwasaki, K., Hirano, A., Yoshihiro, T., Nio, K., Koga, Y., Esaki, M., Ariyama, H., Kusaba, H., Moriyama, T., Ohuchida, K., Nagai, E., Nakamura, M., Oda, Y., Akashi, K. & Baba, E., Oct 1 2018, In : Medicine (United States). 97, 41, e12796.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein–Barr virus-associated gastric cancer

Ohmura, H., Ito, M., Uchino, K., Okada, C., Tanishima, S., Yamada, Y., Momosaki, S., Komoda, M., Kuwayama, M., Yamaguchi, K., Okumura, Y., Nakano, M., Tsuchihashi, K., Isobe, T., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Jan 1 2020, In : FEBS Open Bio. 10, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)