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• Erratum to: Assessing the safety and efficacy of ruxolitinib in a multicenter, open-label study in Japanese patients with myelofibrosis (International Journal of Hematology, (2017), 105, 3, (309-317), 10.1007/s12185-016-2130-z)

  Komatsu, N., Kirito, K., Shimoda, K., Ishikawa, T., Ohishi, K., Ohyashiki, K., Takahashi, N., Okada, H., Amagasaki, T., Yonezu, T. & Akashi, K., Mar 1 2017, In: International journal of hematology. 105, 3, p. 387 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • INCB018424
  • Primary Myelofibrosis
  • Hematology
  • Reading
  • Publications

• Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia

  Elbadry, M. I., Mizumaki, H., Hosokawa, K., Espinoza, J. L., Nakagawa, N., Yoshida, Y., Katagiri, T., Hosomichi, K., Zaimoku, Y., Imi, T., Nguyen, M. A. T., Fujii, Y., Tajima, A., Ogawa, S., Takenaka, K., Akashi, K. & Nakao, S., 2019, In: Haematologica. 104, 10, p. E447-E450

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  1 Citation (Scopus)

• Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells

  Aikawa, Y., Yamagata, K., Katsumoto, T., Shima, Y., Shino, M., Stanley, E. R., Cleary, M. L., Akashi, K., Tenen, D. G. & Kitabayashi, I., Mar 1 2015, In: Cancer Science. 106, 3, p. 227-236 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Leukemia
  • Stem Cells
  • Acute Myeloid Leukemia
  • Maintenance
  • Myeloid-Lymphoid Leukemia Protein
  13 Citations (Scopus)

• Evaluating the association between histological manifestations of cord colitis syndrome with GVHD

  Shimoji, S., Kato, K., Eriguchi, Y., Takenaka, K., Iwasaki, H., Miyamoto, T., Oda, Y., Akashi, K. & Teshima, T., Sep 2013, In: Bone Marrow Transplantation. 48, 9, p. 1249-1252 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Colitis
  • Paneth Cells
  • Metaplasia
  • Fetal Blood
  • Crohn Disease
  17 Citations (Scopus)

• Evaluation of the compliance with antiemetic guidelines for prevention of chemotherapy-induced nausea and vomiting in patients with hematologic malignancy

  Uchida, M., Nakamura, T., Shima, T., Mori, Y., Yoshimoto, G., Kato, K., Shimokawa, M., Hosohata, K., Miyamoto, T. & Akashi, K., 2019, In: Pharmazie. 74, 4, p. 250-254 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Antiemetics
  • Hematologic Neoplasms
  • Nausea
  • Vomiting
  • Guidelines

• Evaluation of the dose and efficacy of ruxolitinib in Japanese patients with myelofibrosis

  Kirito, K., Okamoto, S., Ohishi, K., Tauchi, T., Handa, H., Saito, S., Takenaka, K., Shimoda, K., Oritani, K., Akashi, K., Okada, H., Amagasaki, T., Suzuki, K., Yonezu, T. & Komatsu, N., Jan 1 2018, In: International journal of hematology. 107, 1, p. 92-97 6 p.

  Research output: Contribution to journal › Article › peer-review

  • INCB018424
  • Primary Myelofibrosis
  • Spleen
  • Splenomegaly
  • Placebos
  4 Citations (Scopus)

• Evaluation of the feasibility and efficacy of autologous stem cell transplantation in elderly patients with multiple myeloma

  Muta, T., Miyamoto, T., Fujisaki, T., Ohno, Y., Kamimura, T., Kato, K., Takenaka, K., Iwasaki, H., Eto, T., Takamatsu, Y., Teshima, T. & Akashi, K., 2013, In: Internal Medicine. 52, 1, p. 63-70 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Stem Cell Transplantation
  • Multiple Myeloma
  • Elderly
  • Hematopoietic Stem Cell Transplantation
  • Control Groups
  34 Citations (Scopus)

• Expansion of NKG2C-expressing natural killer cells after umbilical cord blood transplantation in a patient with peripheral T-cell lymphoma with cytotoxic molecules

  Muta, T., Yoshihiro, T., Jinnouchi, F., Aoki, K., Kochi, Y., Shima, T., Takenaka, K., Ogawa, R., Akashi, K. & Oshima, K., 2018, In: Internal Medicine. 57, 6, p. 861-866 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Peripheral T-Cell Lymphoma
  • Fetal Blood
  • Natural Killer Cells
  • Tissue Donors
  • Transplantation
  4 Citations (Scopus)

• Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma

  Kiyasu, J., Miyoshi, H., Hirata, A., Arakawa, F., Ichikawa, A., Niino, D., Sugita, Y., Yufu, Y., Choi, I., Abe, Y., Uike, N., Nagafuji, K., Okamura, T., Akashi, K., Takayanagi, R., Shiratsuchi, M. & Ohshima, K., Nov 5 2015, In: Blood. 126, 19, p. 2193-2201 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell death
  • Lymphoma, Large B-Cell, Diffuse
  • Cells
  • Cell Death
  • Ligands
  258 Citations (Scopus)

• Factors prognostic of eligibility for allogeneic HCT among older patients with AML-CR1 and adverse- or intermediate-risk cytogenetics

  Yamasaki, S., Yoshimoto, G., Ogawa, R., Aoki, K., Higuchi, M., Harada, N., Arima, F., Kondo, S., Matubara, F., Takahashi, T., Uike, N., Miyamoto, T., Okamura, S. & Akashi, K., Jul 18 2015, In: Annals of Hematology. 94, 7, p. 1159-1165 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cytogenetics
  • Acute Myeloid Leukemia
  • Cell Transplantation
  • Allogeneic Cells
  • Karnofsky Performance Status
  3 Citations (Scopus)

• Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes

  Tsuzuki, H., Arinobu, Y., Miyawaki, K., Takaki, A., Ota, S. I., Ota, Y., Mitoma, H., Akahoshi, M., Mori, Y., Iwasaki, H., Niiro, H., Tsukamoto, H. & Akashi, K., Jan 1 2017, In: Immunology. 150, 1, p. 64-73 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-1 Receptor-Like 1 Protein
  • Interleukin-33
  • Granulocytes
  • Hypersensitivity
  • Eosinophils
  10 Citations (Scopus)

• Further assessment of atrial fibrillation as a risk factor for gastroesophageal reflux disease: A multicenter questionnaire survey

  Kubota, S., Nakaji, G., Shimazu, H., Odashiro, K., Maruyama, T. & Akashi, K., 2013, In: Internal Medicine. 52, 21, p. 2401-2407 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastroesophageal Reflux
  • Atrial Fibrillation
  • Discriminant Analysis
  • Dyslipidemias
  • Informed Consent
  7 Citations (Scopus)

• Gastrointestinal Graft-versus-Host Disease Is a Risk Factor for Postengraftment Bloodstream Infection in Allogeneic Hematopoietic Stem Cell Transplant Recipients

  Mori, Y., Yoshimoto, G., Nishida, R., Sugio, T., Miyawaki, K., Shima, T., Nagasaki, Y., Miyake, N., Harada, Y., Kunisaki, Y., Kamezaki, K., Numata, A., Kato, K., Shiratsuchi, M., Maeda, T., Takenaka, K., Iwasaki, H., Shimono, N., Akashi, K. & Miyamoto, T., Nov 2018, In: Biology of Blood and Marrow Transplantation. 24, 11, p. 2302-2309 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Graft vs Host Disease
  • Hematopoietic Stem Cells
  • Transplant Recipients
  • Transplants
  • Infection
  8 Citations (Scopus)

• Generation mechanism of RANKL⁺ effector memory B cells: Relevance to the pathogenesis of rheumatoid arthritis

  Ota, Y., Niiro, H., Ota, S. I., Ueki, N., Tsuzuki, H., Nakayama, T., Mishima, K., Higashioka, K., Jabbarzadeh-Tabrizi, S., Mitoma, H., Akahoshi, M., Arinobu, Y., Kukita, A., Yamada, H., Tsukamoto, H. & Akashi, K., Mar 16 2016, In: Arthritis Research and Therapy. 18, 1, 67.

  Research output: Contribution to journal › Article › peer-review

  • B-Lymphocyte Subsets
  • Rheumatoid Arthritis
  • B-Lymphocytes
  • Interferons
  • Osteoprotegerin
  20 Citations (Scopus)

• Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head

  Sakamoto, Y., Yamamoto, T., Sugano, N., Takahashi, D., Watanabe, T., Atsumi, T., Nakamura, J., Hasegawa, Y., Akashi, K., Narita, I., Miyamoto, T., Takeuchi, T., Ikari, K., Amano, K., Fujie, A., Kubo, T., Tada, Y., Kaneuji, A., Nakamura, H., Miyamura, T. & 70 others, Kabata, T., Yamaji, K., Okawa, T., Sudo, A., Ohzono, K., Tanaka, Y., Yasunaga, Y., Matsuda, S., Imai, Y., Nakashima, Y., Motomura, G., Ikemura, S., Yamaguchi, R., Karasuyama, K., Sonoda, K., Nishii, T., Sakai, T., Takao, M., Irie, T., Asano, T., Iwasaki, N., Atsumi, T., Tamaoki, S., Nakanishi, R., Tanabe, S., Kishida, S., Hagiwara, S., Seki, T., Tsukamoto, H., Niiro, H., Arinobu, Y., Akahoshi, M., Mitoma, H., Ayano, M., Kuroda, T., Toyama, Y., Funayama, A., Hanaoka, H., Yamaoka, K., Kawaguchi, Y., Yamanaka, H., Hosozawa, T., Momohara, S., Chino, K., Fujioka, M., Ueshima, K., Ishida, M., Saito, M., Hayashi, S., Ikegami, A., Ichiseki, T., Mizokawa, S., Ohta, Y., Kajino, Y., Sekiya, F., Higuchi, F., Hasegawa, M., Miyamoto, N., Miyazaki, S., Yamaguchi, T., Ando, W., Saito, K., Nakano, K., Kuroda, Y., Yamasaki, T., Akiyama, M., Kubo, M., Kamatani, Y., Iwamoto, Y. & Ikegawa, S., Dec 1 2017, In: Scientific reports. 7, 1, 15035.

  Research output: Contribution to journal › Article › peer-review

  • Osteonecrosis
  • Genome-Wide Association Study
  • Thigh
  • Big Data
  • Hip Joint
  8 Citations (Scopus)

• Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

  Yamauchi, T., Masuda, T., Canver, M. C., Seiler, M., Semba, Y., Shboul, M., Al-Raqad, M., Maeda, M., Schoonenberg, V. A. C., Cole, M. A., Macias-Trevino, C., Ishikawa, Y., Yao, Q., Nakano, M., Arai, F., Orkin, S. H., Reversade, B., Buonamici, S., Pinello, L., Akashi, K. & 2 others, Bauer, D. E. & Maeda, T., Mar 12 2018, In: Cancer Cell. 33, 3, p. 386-400.e5

  Research output: Contribution to journal › Article › peer-review

  • mRNA decapping enzymes
  • Clustered Regularly Interspaced Short Palindromic Repeats
  • RNA Precursors
  • Metabolic Networks and Pathways
  • Leukemia
  35 Citations (Scopus)

• Graft-versus-host disease targets ovary and causes female infertility in mice

  Shimoji, S., Hashimoto, D., Tsujigiwa, H., Miyawaki, K., Kato, K., Takahashi, S., Ogasawara, R., Jiromaru, T., Iwasaki, H., Miyamoto, T., Akashi, K. & Teshima, T., Mar 2 2017, In: Blood. 129, 9, p. 1216-1225 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Female Infertility
  • Grafts
  • Stem cells
  • Graft vs Host Disease
  • Ovary
  11 Citations (Scopus)

• Guest editorial: Leukemia stem cell

  Akashi, K., Dec 2013, In: International journal of hematology. 98, 6, p. 625-626 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Citation (Scopus)

• Helicobacter cinaedi bacteremia mimicking a flare of systemic lupus erythematosus

  Nishida, R., Shimono, N., Miyake, N., Chong, Y., Shimoda, S., Tsukamoto, H. & Akashi, K., 2017, In: Internal Medicine. 56, 6, p. 725-728 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Helicobacter
  • Bacteremia
  • Systemic Lupus Erythematosus
  • Vasculitis
  • Thrombocytopenia
  4 Citations (Scopus)

• Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack

  Espinoza, J. L., Elbadry, M. I., Chonabayashi, K., Yoshida, Y., Katagiri, T., Harada, K., Nakagawa, N., Zaimoku, Y., Imi, T., Takamatsu, H., Ozawa, T., Maruyama, H., Hassanein, H. A., Noreldin, A. K. A., Takenaka, K., Akashi, K., Hamana, H., Kishi, H., Akatsuka, Y. & Nakao, S., Feb 27 2018, In: Blood Advances. 2, 4, p. 390-400 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Aplastic Anemia
  • Induced Pluripotent Stem Cells
  • Hematopoiesis
  • Hematopoietic Stem Cells
  • T-Lymphocytes
  10 Citations (Scopus)

• Hepatitis C virus infection is an independent prognostic factor in follicular lymphoma

  Shimono, J., Miyoshi, H., Kato, T., Sugio, T., Miyawaki, K., Kamimura, T., Miyagishima, T., Eto, T., Imaizumi, Y., Kato, K., Nagafuji, K., Akashi, K., Seto, M., Teshima, T. & Ohshima, K., 2018, In: Oncotarget. 9, 2, p. 1717-1725 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Follicular Lymphoma
  • Hepacivirus
  • Virus Diseases
  • Hepatitis C Antibodies
  • hemoglobin IV
  4 Citations (Scopus)

• Higher incidence of injection site reactions after subcutaneous bortezomib administration on the thigh compared with the abdomen

  Kamimura, T., Miyamoto, T., Yokota, N., Takashima, S., Chong, Y., Ito, Y. & Akashi, K., Feb 2013, In: European Journal of Haematology. 90, 2, p. 157-161 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Injection Site Reaction
  • Bortezomib
  • Abdomen
  • Thigh
  • Injections
  15 Citations (Scopus)

• High incidence and severity of injection site reactions in the first cycle compared with subsequent cycles of subcutaneous bortezomib

  Kamimura, T., Miyamoto, T., Yokota, N., Aoki, T., Ito, Y. & Akashi, K., Dec 2013, In: International journal of hematology. 98, 6, p. 694-701 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Injection Site Reaction
  • Bortezomib
  • Thigh
  • Incidence
  • Subcutaneous Injections
  3 Citations (Scopus)

• HLA-Haploidentical Peripheral Blood Stem Cell Transplantation with Post-Transplant Cyclophosphamide after Busulfan-Containing Reduced-Intensity Conditioning

  on behalf of the Japan Study Group for Cell Therapy and Transplantation, Sep 1 2015, In: Biology of Blood and Marrow Transplantation. 21, 9, p. 1646-1652 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Peripheral Blood Stem Cell Transplantation
  • Busulfan
  • Cyclophosphamide
  • Hematopoietic Stem Cell Transplantation
  • Transplants
  46 Citations (Scopus)

• Human Herpes Virus-6–Associated Encephalitis/Myelitis Mimicking Calcineurin Inhibitor–Induced Pain Syndrome in Allogeneic Stem Cell Transplantation Recipients

  Yoshimoto, G., Mori, Y., Kato, K., Shima, T., Miyawaki, K., Kikushige, Y., Kamezaki, K., Numata, A., Maeda, T., Takenaka, K., Iwasaki, H., Teshima, T., Akashi, K. & Miyamoto, T., Dec 2018, In: Biology of Blood and Marrow Transplantation. 24, 12, p. 2540-2548 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Encephalitis Viruses
  • Myelitis
  • Calcineurin
  • Allogeneic Cells
  • Stem Cell Transplantation
  3 Citations (Scopus)

• Human STEAP3 maintains tumor growth under hypoferric condition

  Isobe, T., Baba, E., Arita, S., Komoda, M., Tamura, S., Shirakawa, T., Ariyama, H., Takaishi, S., Kusaba, H., Ueki, T. & Akashi, K., Nov 1 2011, In: Experimental Cell Research. 317, 18, p. 2582-2591 10 p.

  Research output: Contribution to journal › Article › peer-review

  • human STEAP1 protein
  • Prostate
  • Iron
  • Antigens
  • Growth
  15 Citations (Scopus)

• Hydrophobic bile acids suppress expression of AE2 in biliary epithelial cells and induce bile duct inflammation in primary biliary cholangitis

  Hisamoto, S., Shimoda, S., Harada, K., Iwasaka, S., Onohara, S., Chong, Y., Nakamura, M., Bekki, Y., Yoshizumi, T., Ikegami, T., Maehara, Y., He, X. S., Gershwin, M. E. & Akashi, K., Dec 1 2016, In: Journal of Autoimmunity. 75, p. 150-160 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Chloride-Bicarbonate Antiporters
  • Cholangitis
  • Bile Acids and Salts
  • Bile Ducts
  • Epithelial Cells
  29 Citations (Scopus)

• Hypoalbuminemia for the prediction of venous thromboembolism and treatment of direct oral anticoagulants in metastatic gastric cancer patients

  Takayoshi, K., Kusaba, H., Aikawa, T., Koreishi, S., Sagara, K., Nakano, M., Komoda, M., Kono, M., Fukata, M., Arita, T., Esaki, T., Akashi, K. & Baba, E., Sep 5 2019, In: Gastric Cancer. 22, 5, p. 988-998 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Hypoalbuminemia
  • Venous Thromboembolism
  • Anticoagulants
  • Stomach Neoplasms
  • Therapeutics
  2 Citations (Scopus)

• Identification and biology of CML stem cells

  Iwasaki, H. & Akashi, K., Jan 1 2015, Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia. Springer Japan, p. 1-10 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Myeloid Progenitor Cells
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive
  • Hematopoietic Stem Cells
  • Protein-Tyrosine Kinases
  • Stem Cell Niche
  1 Citation (Scopus)

• Identification of a Human Clonogenic Progenitor with Strict Monocyte Differentiation Potential: A Counterpart of Mouse cMoPs

  Kawamura, S., Onai, N., Miya, F., Sato, T., Tsunoda, T., Kurabayashi, K., Yotsumoto, S., Kuroda, S., Takenaka, K., Akashi, K. & Ohteki, T., May 16 2017, In: Immunity. 46, 5, p. 835-848.e4

  Research output: Contribution to journal › Article › peer-review

  • Forensic Anthropology
  • Monocytes
  • Granulocyte Precursor Cells
  • Myeloid Cells
  • Dendritic Cells
  33 Citations (Scopus)

• Identification of human erythroid lineage-committed progenitors

  Mori, Y., Akashi, K. & Weissman, I. L., May 1 2016, In: [Rinsho ketsueki] The Japanese journal of clinical hematology. 57, 5, p. 585-591 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Forensic Anthropology
  • Megakaryocytes
  • Megakaryocyte-Erythroid Progenitor Cells
  • Population
  • Erythrocytes
  1 Citation (Scopus)

• Identification of unipotent megakaryocyte progenitors in human hematopoiesis

  Miyawaki, K., Iwasaki, H., Jiromaru, T., Kusumoto, H., Yurino, A., Sugio, T., Uehara, Y., Odawara, J., Daitoku, S., Kunisaki, Y., Mori, Y., Arinobu, Y., Tsuzuki, H., Kikushige, Y., Iino, T., Kato, K., Takenaka, K., Miyamoto, T., Maeda, T. & Akashi, K., Jun 22 2017, In: Blood. 129, 25, p. 3332-3343 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Megakaryocyte Progenitor Cells
  • Megakaryocytes
  • Hematopoiesis
  • Cells
  • Macrophages
  28 Citations (Scopus)

• Immunosuppressant therapy successfully improved regorafenib-induced severe hepatic injury in a patient with metastatic gastrointestinal stromal tumor: A case report

  Kuwayama, M., Uchino, K., Takayoshi, K., Komoda, M., Kohjima, M., Nakamuta, M., Momosaki, S., Kusaba, H., Akashi, K. & Baba, E., Jan 2016, In: Oncology Letters. 11, 1, p. 85-88 4 p.

  Research output: Contribution to journal › Article › peer-review

  • regorafenib
  • Gastrointestinal Stromal Tumors
  • Immunosuppressive Agents
  • Prednisolone
  • Liver
  5 Citations (Scopus)

• Impact of CYP3A5, POR, and CYP2C19 Polymorphisms on Trough Concentration to Dose Ratio of Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplantation

  Suetsugu, K., Mori, Y., Yamamoto, N., Shigematsu, T., Miyamoto, T., Egashira, N., Akashi, K. & Masuda, S., May 15 2019, In: International journal of molecular sciences. 20, 10

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • transplantation
  • Stem cells
  • stem cells
  • Cytochrome P-450 CYP2C19
  • polymorphism
  9 Citations (Scopus)

• Impaired deformability of erythrocytes in diabetic rat and human: Investigation by the nickel-mesh-filtration technique

  Saito, K., Kogawa, Y., Fukata, M., Odashiro, K., Maruyama, T., Akashi, K. & Fujino, T., Dec 2011, In: Journal of Biorheology. 25, 1-2, p. 18-26 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Nickel
  • Rats
  • Formability
  • Rat control
  • Microcirculation
  7 Citations (Scopus)

• Impaired erythrocyte deformability in patients with coronary risk factors: Significance of nonvalvular atrial fibrillation

  Odashiro, K., Maruyama, T., Yokoyama, T., Nakamura, H., Fukata, M., Yasuda, S., Saito, K., Fujino, T. & Akashi, K., Oct 2013, In: Journal of Atrial Fibrillation. 6, 3, p. 6-12 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Erythrocyte Deformability
  • Atrial Fibrillation
  • Coronary Artery Disease, Autosomal Dominant, 1
  • Demography
  • Stable Angina

• Increased CD226 expression on CD8⁺ T cells is associated with upregulated cytokine production and endothelial cell injury in patients with systemic sclerosis

  Ayano, M., Tsukamoto, H., Kohno, K., Ueda, N., Tanaka, A., Mitoma, H., Akahoshi, M., Arinobu, Y., Niiro, H., Horiuchi, T. & Akashi, K., Aug 1 2015, In: Journal of Immunology. 195, 3, p. 892-900 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Systemic Scleroderma
  • Endothelial Cells
  • Cytokines
  • T-Lymphocytes
  • Wounds and Injuries
  24 Citations (Scopus)

• Increased Syk phosphorylation leads to overexpression of TRAF6 in peripheral B cells of patients with systemic lupus erythematosus

  Iwata, S., Yamaoka, K., Niiro, H., Jabbarzadeh-Tabrizi, S., Wang, S. P., Kondo, M., Yoshikawa, M., Akashi, K. & Tanaka, Y., Jun 3 2015, In: Lupus. 24, 7, p. 695-704 10 p.

  Research output: Contribution to journal › Article › peer-review

  • TNF Receptor-Associated Factor 6
  • Systemic Lupus Erythematosus
  • B-Lymphocytes
  • Phosphorylation
  • 2-(7-(3,4-dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide
  14 Citations (Scopus)

• Influence of common cardiac drugs on gastroesophageal reflux disease: Multicenter questionnaire survey

  Nakaji, G., Fujihara, M., Fukata, M., Yasuda, S., Odashiro, K., Maruyama, T. & Akashi, K., Sep 2011, In: International Journal of Clinical Pharmacology and Therapeutics. 49, 9, p. 555-563 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastroesophageal Reflux
  • Calcium Channel Blockers
  • Pharmaceutical Preparations
  • Warfarin
  • Medicine
  7 Citations (Scopus)

• Influence of medical history in parents or siblings on the development of systemic lupus erythematosus among Japanese females

  Kyushu Sapporo SLE (KYSS) Study Group, 2016, In: International Medical Journal. 23, 5, p. 466-469 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Systemic Lupus Erythematosus
  • Siblings
  • Parents
  • Autoimmune Diseases
  • Rheumatoid Arthritis

• Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets

  Karube, K., Enjuanes, A., Dlouhy, I., Jares, P., Martin-Garcia, D., Nadeu, F., Ordóñez, G. R., Rovira, J., Clot, G., Royo, C., Navarro, A., Gonzalez-Farre, B., Vaghefi, A., Castellano, G., Rubio-Perez, C., Tamborero, D., Briones, J., Salar, A., Sancho, J. M., Mercadal, S. & 19 others, Gonzalez-Barca, E., Escoda, L., Miyoshi, H., Ohshima, K., Miyawaki, K., Kato, K., Akashi, K., Mozos, A., Colomo, L., Alcoceba, M., Valera, A., Carrió, A., Costa, D., Lopez-Bigas, N., Schmitz, R., Staudt, L. M., Salaverria, I., López-Guillermo, A. & Campo, E., Mar 1 2018, In: Leukemia. 32, 3, p. 675-684 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Lymphoma, Large B-Cell, Diffuse
  • Mutation
  • Genes
  • B-Lymphocytes
  • Gene Dosage
  63 Citations (Scopus)

• Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis

  Shimoda, S., Harada, K., Niiro, H., Shirabe, K., Taketomi, A., Maehara, Y., Tsuneyama, K., Nakanuma, Y., Leung, P., Ansari, A. A., Gershwin, M. E. & Akashi, K., Apr 2011, In: Hepatology. 53, 4, p. 1270-1281 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Biliary Liver Cirrhosis
  • Toll-Like Receptors
  • Bile Ducts
  • Natural Killer Cells
  • Ligands
  88 Citations (Scopus)

• Intraluminal superior vena cava metastasis from adenosquamous carcinoma of the duodenum: A case report

  Takayoshi, K., Ariyama, H., Tamura, S., Yoda, S., Arita, T., Yamaguchi, T., Ozono, K., Yamamoto, H., Inadomi, K., Kumagai, H., Tanaka, M., Okumura, Y., Sagara, K., Nio, K., Nakano, M., Arita, S., Kusaba, H., Odashiro, K., Oda, Y., Akashi, K. & 1 others, Baba, E., Jan 2016, In: Oncology Letters. 11, 1, p. 605-609 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Adenosquamous Carcinoma
  • Superior Vena Cava
  • Duodenum
  • Neoplasm Metastasis
  • Central Venous Catheters
  3 Citations (Scopus)

• Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin

  Hirano, G., Izumi, H., Yasuniwa, Y., Shimajiri, S., Ke-Yong, W., Sasagiri, Y., Kusaba, H., Matsumoto, K., Hasegawa, T., Akimoto, M., Akashi, K. & Kohno, K., Apr 2011, In: International journal of oncology. 38, 4, p. 893-902 10 p.

  Research output: Contribution to journal › Article › peer-review

  • riboflavin kinase
  • Cisplatin
  • Flavin-Adenine Dinucleotide
  • Glutathione Reductase
  • Flavin Mononucleotide
  15 Citations (Scopus)

• Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer

  Makiyama, A., Arimizu, K., Hirano, G., Makiyama, C., Matsushita, Y., Shirakawa, T., Ohmura, H., Komoda, M., Uchino, K., Inadomi, K., Arita, S., Ariyama, H., Kusaba, H., Shinohara, Y., Kuwayama, M., Kajitani, T., Oda, H., Esaki, T., Akashi, K. & Baba, E., May 1 2018, In: Gastric Cancer. 21, 3, p. 464-472 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Irinotecan
  • Stomach Neoplasms
  • Salvage Therapy
  • Survival
  • Therapeutics
  13 Citations (Scopus)

• Large-scale genome analysis of bovine commensal Escherichia coli reveals that bovine-adapted E. Coli lineages are serving as evolutionary sources of the emergence of human intestinal pathogenic strains

  Arimizu, Y., Kirino, Y., Sato, M. P., Uno, K., Sato, T., Gotoh, Y., Auvray, F., Brugere, H., Oswald, E., Mainil, J. G., Anklam, K. S., Döpfer, D., Yoshino, S., Ooka, T., Tanizawa, Y., Nakamura, Y., Iguchi, A., Morita-Ishihara, T., Ohnishi, M., Akashi, K. & 2 others, Hayashi, T. & Ogura, Y., 2019, In: Genome Research. 29, 9, p. 1495-1505 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Enteropathogenic Escherichia coli
  • Cattle
  • Escherichia coli
  • Genome
  • Virulence
  8 Citations (Scopus)

• Light chain deposition disease in an older adult patient successfully treated with long-term administration of bortezomib, melphalan and prednisone

  Hiyamuta, H., Yamada, S., Matsukuma, Y., Tsuchimoto, A., Nakano, T., Taniguchi, M., Masutani, K., Yoshimoto, G., Muta, T., Akashi, K., Kitazono, T. & Tsuruya, K., 2016, In: Internal Medicine. 55, 10, p. 1319-1325 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Bortezomib
  • Melphalan
  • Prednisone
  • VMP regimen
  • Light
  1 Citation (Scopus)

• Lingual alveolar soft part sarcoma responsive to pazopanib: A case report

  Yoshihiro, T., Tsuchihashi, K., Nio, K., Arita, S., Nakano, T., Yasumatsu, R., Jiroumaru, R., Ariyama, H., Kusaba, H., Oda, Y., Akashi, K. & Baba, E., Nov 2017, In: Medicine (United States). 96, 44, e8470.

  Research output: Contribution to journal › Article › peer-review

  • Alveolar Soft Part Sarcoma
  • pazopanib
  • Tongue
  • cediranib
  • Articulation Disorders
  1 Citation (Scopus)

• Long-term efficacy of infliximab treatment and the predictors of treatment outcomes in patients with refractory uveitis associated with Behçet's disease

  Ueda, S., Akahoshi, M., Takeda, A., Inoue, Y., Omoto, A., Ayano, M., Kimoto, Y., Mitoma, H., Arinobu, Y., Niiro, H., Tsukamoto, H., Horiuchi, T., Hikita, S-I., Fukuhara, T., Ishibashi, T., Sonoda, K-H. & Akashi, K., Mar 2018, In: European journal of rheumatology. 5, 1, p. 9-15 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Infliximab
  • Uveitis
  • Cytokines
  • Serum
  • Interleukin-2

• M2 macrophages enhance pathological neovascularization in the mouse model of oxygen-induced retinopathy

  Zhou, Y., Yoshida, S., Nakao, S., Yoshimura, T., Kobayashi, Y., Nakama, T., Kubo, Y., Miyawaki, K., Yamaguchi, M., Ishikawa, K., Oshima, Y., Akashi, K. & Ishibashi, T., 2015, In: Investigative Ophthalmology and Visual Science. 56, 8, p. 4767-4777 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Pathologic Neovascularization
  • Oxygen
  • Macrophages
  • Retinal Neovascularization
  • Endothelial Cells
  33 Citations (Scopus)