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  • Dongchon Kang
2016

The expression of ubiquitous mitochondrial creatine kinase is downregulated as prostate cancer progressionz

Amamoto, R., Uchiumi, T., Yagi, M., Monji, K., Song, Y. H., Oda, Y., Shiota, M., Yokomizo, A., Naito, S. & Kang, D., Jan 1 2016, In : Journal of Cancer. 7, 1, p. 50-59 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

Analysis of influenza A/H3N2 neuraminidase genes obtained from influenza patients in the 2011/12 and 2012/13 seasons in Japan

Ikematsu, H., Chong, Y., Shirane, K., Toh, H., Sasaki, H., Koga, Y., Urata, M., Hotta, T., Uchiumi, T. & Kang, D., Jan 1 2015, In : Fukuoka igaku zasshi = Hukuoka acta medica. 106, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

Analysis of the Neuraminidase Amino Acid Sequences of Influenza A/H1N1pdm09, A/H3N2, and B Viruses Isolated from Influenza Patients in the 2013/14 Japanese Influenza Season

Ikematsu, H., Chong, Y., Shirane, K., Toh, H., Sasaki, H., Koga, Y., Matsumoto, S., Hotta, T., Uchiumi, T. & Kang, D., Aug 1 2015, In : Fukuoka igaku zasshi = Hukuoka acta medica. 106, 8, p. 231-239 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Association of hemoglobin A1c and glycated albumin with carotid atherosclerosis in community-dwelling Japanese subjects: The Hisayama Study

Mukai, N., Ninomiya, T., Hata, J., Hirakawa, Y., Ikeda, F., Fukuhara, M., Hotta, T., Koga, M., Nakamura, U., Kang, D., Kitazono, T. & Kiyohara, Y., Jun 24 2015, In : Cardiovascular Diabetology. 14, 1, 84.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Collaborative derivation of reference intervals for major clinical laboratory tests in Japan

on behalf of the Committee on Common Reference Intervals, Japan Society of Clinical Chemistry, Jan 1 2015, In : Annals of Clinical Biochemistry. 53, 3, p. 347-356 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Comparison of two types of matrix-assisted laser desorption/ionization time-of-flight mass spectrometer for the identification and typing of clostridium difficile

Kiyosuke, M., Kibe, Y., Oho, M., Kusaba, K., Shimono, N., Hotta, T., Kang, D., Shoubuike, T. & Miyamoto, H., Oct 2015, In : Journal of Medical Microbiology. 64, 10, p. 1144-1150 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Crystal structure of the anion exchanger domain of human erythrocyte band 3

Arakawa, T., Kobayashi-Yurugi, T., Alguel, Y., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Ikeda-Suno, C., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A. D., Kobayashi, T., Hamasaki, N. & Iwata, S., Nov 6 2015, In : Science. 350, 6261, p. 680-684 5 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

Disruption of mitochondrial fission in the liver protects mice from diet-induced obesity and metabolic deterioration

Wang, L., Ishihara, T., Ibayashi, Y., Tatsushima, K., Setoyama, D., Hanada, Y., Takeichi, Y., Sakamoto, S., Yokota, S., Mihara, K., Kang, D., Ishihara, N., Takayanagi, R. & Nomura, M., Oct 24 2015, In : Diabetologia. 58, 10, p. 2371-2380 10 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Evaluation of the short-term stability of specimens for clinical laboratory testing

Ikeda, K., Ichihara, K., Hashiguchi, T., Hidaka, Y., Kang, D., Maekawa, M., Matsumoto, H., Matsushita, K., Okubo, S., Tsuchiya, T. & Furuta, K., Apr 1 2015, In : Biopreservation and Biobanking. 13, 2, p. 135-143 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Mass Spectrometry Based Metabolic Study; Application to Mitochondria Dysfunction Model for Biomarker Discovery

Setoyama, D. & Kang, D., Oct 1 2015, In : Fukuoka Acta Medica. 106, 10, p. 267-272 6 p.

Research output: Contribution to journalReview article

Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways

Hirota, Y., Yamashita, S. I., Kurihara, Y., Jin, X., Aihara, M., Saigusa, T., Kang, D. & Kanki, T., Jan 1 2015, In : Autophagy. 11, 2, p. 332-343 12 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress

Ikeda, M., Ide, T., Fujino, T., Arai, S., Saku, K., Kakino, T., Tyynismaa, H., Yamasaki, T., Yamada, K. I., Kang, D., Suomalainen, A. & Sunagawa, K., Mar 30 2015, In : PloS one. 10, 3, e0119687.

Research output: Contribution to journalArticle

50 Citations (Scopus)

The JLAC Coding System for Clinical Laboratory Tests

Kang, D., Jan 1 2015, In : Rinsho byori. The Japanese journal of clinical pathology. 63, 1, p. 129-132 4 p.

Research output: Contribution to journalArticle

2014

[Surveillance report of drug-resistant bacteria from 2007 to 2012 in Saga Prefecture, Japan (the second report)].

Kiyosuke, M., Nagasawa, Z., Hotta, T., Utsumi, T., Kang, D. & Miyamoto, H., Jan 1 2014, In : Rinsho byori. The Japanese journal of clinical pathology. 62, 6, p. 546-551 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A novel mutation in protein C gene (PROC) causing severe phenotype in neonatal period

Unal, S., Gumruk, F., Yigit, S., Tuncer, M., Tavil, B., Cil, O., Takci, S., Urata, M., Hotta, T., Kang, D. & Cetin, M., Jan 1 2014, In : Pediatric Blood and Cancer. 61, 4, p. 763-764 2 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1

Baba, T., Otake, H., Sato, T., Miyabayashi, K., Shishido, Y., Wang, C. Y., Shima, Y., Kimura, H., Yagi, M., Ishihara, Y., Hino, S., Ogawa, H., Nakao, M., Yamazaki, T., Kang, D., Ohkawa, Y., Suyama, M., Chung, B. C. & Morohashi, K. I., Apr 14 2014, In : Nature communications. 5, 3634.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Improvement and evaluation of a 1,2-dioleoylglycerol method for measuring pancreatic lipase catalytic activity in serum

Iizuka, Y., Yamashita, K., Sakasegawa, S. I., Hanada, T., Tani, W., Adachi, H., Haga, R., Yamaguchi, M., Kurotani, W., Sekiguchi, M., Osawa, S., Hosogaya, S., Kang, D. & Ueda, S., Aug 1 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 8, p. e171-e173

Research output: Contribution to journalLetter

Staphylococcal endocarditis as the first manifestation of heritable protein S deficiency in childhood

Hoshina, T., Nakashima, Y., Sato, D., Nanishi, E., Nishio, H., Nagata, H., Yamamura, K., Doi, T., Shiokawa, Y., Koga, Y., Kang, D., Ohga, S. & Hara, T., Feb 2014, In : Journal of Infection and Chemotherapy. 20, 2, p. 128-130 3 p.

Research output: Contribution to journalArticle

Thresholds of various glycemic measures for diagnosing diabetes based on prevalence of retinopathy in community-dwelling Japanese subjects: The Hisayama Study

Mukai, N., Yasuda, M., Ninomiya, T., Hata, J., Hirakawa, Y., Ikeda, F., Fukuhara, M., Hotta, T., Koga, M., Nakamura, U., Kang, D., Kitazono, T. & Kiyohara, Y., Feb 17 2014, In : Cardiovascular Diabetology. 13, 1, 45.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Tor and the Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast

Aihara, M., Jin, X., Kurihara, Y., Yoshida, Y., Matsushima, Y., Oku, M., Hirota, Y., Saigusa, T., Aoki, Y., Uchiumi, T., Yamamoto, T., Sakai, Y., Kang, D. & Kanki, T., 2014, In : Journal of cell science. 127, 14, p. 3184-3196 13 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2013

[Mitochondrial stress in diseases].

Kang, D., Jan 1 2013, In : Unknown Journal. 85, 3, p. 160-166 7 p.

Research output: Contribution to journalReview article

[Molecular tests of mitochondrial genome].

Kang, D., Jan 1 2013, In : Unknown Journal. 61, 11, p. 1035-1043 9 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

[The functional and pathological analysis of mitochondrial protein p32].

Uchiumi, T. & Kang, D., Jun 2013, In : Unknown Journal. 61, 6, p. 493-500 8 p.

Research output: Contribution to journalReview article

Casein kinase 2 is essential for mitophagy

Kanki, T., Kurihara, Y., Jin, X., Goda, T., Ono, Y., Aihara, M., Hirota, Y., Saigusa, T., Aoki, Y., Uchiumi, T. & Kang, D., Sep 1 2013, In : EMBO Reports. 14, 9, p. 788-794 7 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Takazaki, S., Yamaza, H., Nonaka, K. & Kang, D., May 20 2013, In : Bioscience reports. 33, 2, p. 217-227 11 p., e00021.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction.

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Takazaki, S., Yamaza, H., Nonaka, K. & Kang, D., 2013, In : Bioscience Reports. 33, 2

Research output: Contribution to journalArticle

Effects of DNA lesions on the transcription reaction of mitochondrial RNA polymerase: Implications for bypass RNA synthesis on oxidative DNA lesions

Nakanishi, N., Fukuoh, A., Kang, D., Iwai, S. & Kuraoka, I., Jan 1 2013, In : Mutagenesis. 28, 1, p. 117-123 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Effects of overexpression of mitochondrial transcription factor A on lifespan and oxidative stress response in Drosophila melanogaster

Matsuda, T., Kanki, T., Tanimura, T., Kang, D. & Matsuura, E. T., Jan 11 2013, In : Biochemical and Biophysical Research Communications. 430, 2, p. 717-721 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Mutation and functional analysis of ABCC2/multidrug resistance protein 2 in a Japanese patient with Dubin-Johnson syndrome

Uchiumi, T., Tanamachi, H., Kuchiwaki, K., Kajita, M., Matsumoto, S., Yagi, M., Kanki, T. & Kang, D., May 1 2013, In : Hepatology Research. 43, 5, p. 569-575 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Neonatal asphyxia and renal failure as the presentation of non-inherited protein C deficiency

Matsunaga, Y., Ohga, S., Kinjo, T., Ochiai, M., Ito, N., Doi, T., Kang, D. & Hara, T., Mar 1 2013, In : Journal of Perinatology. 33, 3, p. 239-241 3 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Paediatric presentation and outcome of congenital protein C deficiency in Japan

Ohga, S., Kang, D., Kinjo, T., Ochiai, M., Doi, T., Ishimura, M., Kayamori, Y., Urata, M., Yamamoto, J., Suenobu, S. I., Kanegane, H., Ikenoue, T., Shirahata, A. & Hara, T., May 1 2013, In : Haemophilia. 19, 3, p. 378-384 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Protein C deficiency as the major cause of thrombophilias in childhood

Ohga, S., Ishiguro, A., Takahashi, Y., Shima, M., Taki, M., Kaneko, M., Fukushima, K., Kang, D. & Hara, T., Jun 2013, In : Pediatrics International. 55, 3, p. 267-271 5 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)

The clinical evaluation of high risk human papillomavirus (HPV) genotyping in cervical cancer tissue using a novel electric DNA chip-based diagnostic system

Koga, Y., Urata, M., Uchiumi, T., Sato, O., Kobayashi, H. & Kang, D., Apr 1 2013, In : Japanese Journal of Clinical Chemistry. 42, 2, p. 140-145 6 p.

Research output: Contribution to journalArticle

2012

1,2-Dioleoylglycerol method for pancreatic lipase catalytic activity in serum

Iizuka, Y., Ueda, S., Hanada, T., Tani, W., Adachi, H., Haga, R., Yamaguchi, M., Kurotani, W., Sekiguchi, M., Kang, D. & Sakasegawa, S. I., Mar 1 2012, In : Clinical Chemistry and Laboratory Medicine. 50, 3, p. 475-481 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Arg 901 in the AE1 C-terminal tail is involved in conformational change but not in substrate binding

Takazaki, S., Abe, Y., Yamaguchi, T., Yagi, M., Ueda, T., Kang, D. & Hamasaki, N., Mar 1 2012, In : Biochimica et Biophysica Acta - Biomembranes. 1818, 3, p. 658-665 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Cardiac-specific deletion of SOCS-3 prevents development of left ventricular remodeling after acute myocardial infarction

Oba, T., Yasukawa, H., Hoshijima, M., Sasaki, K. I., Futamata, N., Fukui, D., Mawatari, K., Nagata, T., Kyogoku, S., Ohshima, H., Minami, T., Nakamura, K., Kang, D., Yajima, T., Knowlton, K. U. & Imaizumi, T., Feb 28 2012, In : Journal of the American College of Cardiology. 59, 9, p. 838-852 15 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Determination of serum pancreatic lipase activity measurement as a candidate reference procedure

Iizuka, Y., Tani, W., Adachi, H., Yamaguchi, M., Kurotani, W., Sakasegawa, S. I., Imamura, S., Ueda, S., Haga, R., Hanada, T., Sekiguchi, M. & Kang, D., Jan 31 2012, In : Japanese Journal of Clinical Chemistry. 41, 1, p. 72-85 14 p.

Research output: Contribution to journalArticle

Effect of mitochondrial transcription factor a overexpression on motor neurons in amyotrophic lateral sclerosis model mice

Morimoto, N., Miyazaki, K., Kurata, T., Ikeda, Y., Matsuura, T., Kang, D., Ide, T. & Abe, K., Jun 1 2012, In : Journal of Neuroscience Research. 90, 6, p. 1200-1208 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Effects of penicillin on clinical tests with special reference to serum albumin measured by a modified BCP method

Kayamori, Y., Ono, M. & Kang, D., Jan 1 2012, Penicillin: Biosynthesis, Applications and Adverse Effects. Nova Science Publishers, Inc., p. 113-126 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,866 clinical isolates obtained from 72 centers in 2010

Yamaguchi, K., Ohno, A., Ishii, Y., Tateda, K., Iwata, M., Akizawa, K., Shimizu, C., Hayashi, T., Kaku, M., Kunishima, H., Kitagawa, M., Miki, M., Kawamura, C., Yasujima, M., Tashiro, H., Horiuchi, H., Katayama, Y., Suwabe, A., Kurota, M., Kikuchi, K. & 124 others, Kuroki, S., Hirayama, K., Takahashi, T., Gotou, T., Morikane, K., Ota, R., Nakagawa, T., Moriya, K., Murata, M., Yoneyama, A., Kondou, S., Misawa, S., Sekine, I., Shiotani, J., Nakayama, T., Yagoshi, M., Horiuchi, H., Tazawa, Y., Kanno, H., Aihara, M., Yamazaki, K., Okamoto, H., Haruki, K., Yazawa, J., Nagano, E., Okada, M., Fukuda, Y., Ikari, H., Maesaki, S., Hashikita, G., Sumitomo, M., Miyajima, E., Saito, T., Taniguchi, N., Hishinuma, A., Yamamoto, Y., Okamoto, Y., Yamane, N., Maruyama, R., Kawashima, C., Murakami, M., Yomoda, S., Machida, T., Ozaki, Y., Uchida, T., Baba, H., Sugiura, Y., Kondo, K., Yamada, T., Gonda, H., Yamaguchi, I., Akahori, T., Uemura, K., Maekawa, M., Yoshimura, H., Nakatani, K., Matsushima, Y., Nobori, T., Fujimoto, Y., Asano, Y., Morinaga, A., Fujita, S., Senda, Y., Hida, Y., Yamashita, M., Yoshida, H., Ichiyama, S., Okabe, H., Shigeta, M., Shimizu, K., Masaki, H., Heijyou, H., Nakaya, H., Takubo, T., Kusakabe, T., Higashiyama, T., Yoshida, H., Morishita, H., Matsuo, S., Kono, H., Fukuda, S., Sano, R., Yuzuki, Y., Ikeda, N., Idomuki, M., Yamamoto, G., Kinoshita, S., Kawano, S., Doi, M., Watanabe, Y., Shimizu, S., Oka, M., Kobashi, Y., Kusano, N., Fujiwara, H., Murota, H., Morishita, S., Nagai, A., Moriyama, H., Taniguchi, Y., Negayama, K., Murao, K., Miyamoto, H., Sugiura, T., Morita, T., Tou, H., Matsunaga, A., Kang, D., Kiyosuke, M., Mashiba, K., Yanagihara, K., Matsuda, J., Kohno, S., Aoki, Y., Nagasawa, Z., Kusaba, K., Hiramatsu, K., Saikawa, T., Miyanohara, H., Saeki, Y., Takajo, I., Okayama, A., Yamane, N. & Nakasone, I., Jun 1 2012, In : Japanese Journal of Antibiotics. 65, 3, p. 181-206 26 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)

Localization of mRNAs encoding human mitochondrial oxidative phosphorylation proteins

Matsumoto, S., Uchiumi, T., Saito, T., Yagi, M., Takazaki, S., Kanki, T. & Kang, D., May 1 2012, In : Mitochondrion. 12, 3, p. 391-398 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
161 Citations (Scopus)

MtSSB may sequester UNG1 at mitochondrial ssDNA and delay uracil processing until the dsDNA conformation is restored

Wollen Steen, K., Doseth, B., P. Westbye, M., Akbari, M., Kang, D., Falkenberg, M. & Slupphaug, G., Jan 2 2012, In : DNA Repair. 11, 1, p. 82-91 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

P32/gC1qR is indispensable for fetal development and mitochondrial translation: Importance of its RNA-binding ability

Yagi, M., Uchiumi, T., Takazaki, S., Okuno, B., Nomura, M., Yoshida, S. I., Kanki, T. & Kang, D., Oct 1 2012, In : Nucleic acids research. 40, 19, p. 9717-9737 21 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients

Fang, J. X., Uchiumi, T., Yagi, M., Matsumoto, S., Amamoto, R., Saito, T., Takazaki, S., Kanki, T., Yamaza, H., Nonaka, K. & Kang, D., Dec 1 2012, In : Bioscience reports. 32, 6, p. 631-639 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Recombinant mitochondrial transcription factor A protein inhibits nuclear factor of activated T cells signaling and attenuates pathological hypertrophy of cardiac myocytes

Fujino, T., Ide, T., Yoshida, M., Onitsuka, K., Tanaka, A., Hata, Y., Nishida, M., Takehara, T., Kanemaru, T., Kitajima, N., Takazaki, S., Kurose, H., Kang, D. & Sunagawa, K., Jul 1 2012, In : Mitochondrion. 12, 4, p. 449-458 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Ribonucleoprotein Y-box-binding protein-1 regulates mitochondrial oxidative phosphorylation (OXPHOS) protein expression after serum stimulation through binding to OXPHOS mRNA

Matsumoto, S., Uchiumi, T., Tanamachi, H., Saito, T., Yagi, M., Takazaki, S., Kanki, T. & Kang, D., Apr 15 2012, In : Biochemical Journal. 443, 2, p. 573-584 12 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

The physiological role of mitophagy: New insights into phosphorylation events

Hirota, Y., Kang, D. & Kanki, T., Apr 19 2012, In : International Journal of Cell Biology. 354914.

Research output: Contribution to journalReview article

33 Citations (Scopus)

The role of TFAM-associated proteins in mitochondrial RNA metabolism

Uchiumi, T. & Kang, D., May 1 2012, In : Biochimica et Biophysica Acta - General Subjects. 1820, 5, p. 565-570 6 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)