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2018
7 Citations (Scopus)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Antibodies
Neural Conduction
Immunotherapy
Cerebrospinal Fluid Proteins
Neuromyelitis Optica
Gold
Dimethyl Fumarate
3 Citations (Scopus)

Restoration of a conduction block after the long-term treatment of CIDP with anti-neurofascin 155 antibodies: Follow-up of a case over 23 years

Koike, H., Nishi, R., Ikeda, S., Kawagashira, Y., Iijima, M., Atsuta, N., Nakamura, T., Hirayama, M., Ogata, H., Yamasaki, R., Kira, J. I., Katsuno, M. & Sobue, G., Jan 1 2018, In : Internal Medicine. 57, 14, p. 2061-2066 6 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Hypesthesia
Antibodies
Neural Conduction
Action Potentials

The contribution of glial inflammation in the pathogenesis of multiple sclerosis

Yamasaki, R. & Kira, J. I., Jan 1 2018, In : Neuro-Ophthalmology Japan. 35, 1, p. 4-10 7 p.

Research output: Contribution to journalArticle

Connexins
Neuroglia
Multiple Sclerosis
Inflammation
Recurrence

The neuropathological study of myelin oligodendrocyte glycoprotein in the temporal lobe of schizophrenia patients

Marui, T., Torii, Y., Iritani, S., Sekiguchi, H., Habuchi, C., Fujishiro, H., Oshima, K., Niizato, K., Hayashida, S., Masaki, K., Kira, J. & Ozaki, N., Aug 1 2018, In : Acta Neuropsychiatrica. 30, 4, p. 232-240 9 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Temporal Lobe
Schizophrenia
Oligodendroglia
Brain
Vesicular Glutamate Transport Protein 2
STAT3 Transcription Factor
Transcriptional Activation
Glutamic Acid
Spinal Cord
2017
3 Citations (Scopus)

A case of anti-neurofascin 155 antibody-positive combined central and peripheral demyelination successfully treated with plasma exchange

Shimizu, M., Koda, T., Nakatsuji, Y., Ogata, H., Kira, J. I. & Mochizuki, H., Jan 1 2017, In : Clinical Neurology. 57, 1, p. 41-44 4 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Plasma Exchange
Demyelinating Diseases
Cerebrospinal Fluid
Anti-Idiotypic Antibodies
MELAS Syndrome
Rhabdomyolysis
Status Epilepticus
Stroke

A case of stiff-person syndrome due to secondary adrenal insufficiency

Mizuno, Y., Yamaguchi, H., Uehara, T., Yamashita, K., Yamasaki, R. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 6, p. 298-302 5 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Adrenal Insufficiency
Contracture
Hypopituitarism
Muscles

A case of superficial siderosis ameliorated after closure of dural deficit detected by MRI-CISS (constructive interference in steady state) imaging

Sakoda, A., Yamashita, K. I., Hayashida, M., Iwamoto, Y., Yamasaki, R. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 4, p. 180-183 4 p.

Research output: Contribution to journalArticle

Siderosis
Dizziness
Ataxia
Headache
Cerebrospinal Fluid
2 Citations (Scopus)

A novel mutation in FGD4 causes Charcot–Marie–Tooth disease type 4H with cranial nerve involvement

Kondo, D., Shinoda, K., Yamashita, K. I., Yamasaki, R., Hashiguchi, A., Takashima, H. & Kira, J. I., Oct 2017, In : Neuromuscular Disorders. 27, 10, p. 959-961 3 p.

Research output: Contribution to journalArticle

Cranial Nerves
Muscle Weakness
Scoliosis
Bilateral Hearing Loss
Facial Muscles
5 Citations (Scopus)

Apomorphine Therapy for Neuronal Insulin Resistance in a Mouse Model of Alzheimer's Disease

Nakamura, N., Ohyagi, Y., Imamura, T., Yanagihara, Y. T., Iinuma, K. M., Soejima, N., Murai, H., Yamasaki, R. & Kira, J. I., Jan 1 2017, In : Journal of Alzheimer's Disease. 58, 4, p. 1151-1161 11 p.

Research output: Contribution to journalArticle

Apomorphine
Insulin Resistance
Alzheimer Disease
Insulysin
Brain
3 Citations (Scopus)

Cerebral blood flow laterality derived from arterial spin labeling as a biomarker for assessing the disease severity of parkinson's disease

Yamashita, K., Hiwatashi, A., Togao, O., Kikuchi, K., Yamaguchi, H., Suzuki, Y., Kamei, R., Yamasaki, R., Kira, J. I. & Honda, H., Jun 2017, In : Journal of Magnetic Resonance Imaging. 45, 6, p. 1821-1826 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Parkinson Disease
Biomarkers
Caudate Nucleus
Globus Pallidus
1 Citation (Scopus)

Clinical characteristics of atrial fibrillation-related cardioembolic stroke in patients aged 80 years or older

Tanaka, K., Yamada, T., Torii, T., Matsumoto, S., Yoshimura, T., Takase, K. I., Wakata, Y., Nakashima, N., Kira, J. I. & Murai, H., May 2017, In : Geriatrics and Gerontology International. 17, 5, p. 708-713 6 p.

Research output: Contribution to journalArticle

stroke
Atrial Fibrillation
Stroke
mortality
Mortality
Amyotrophic Lateral Sclerosis
Neuroglia
Motor Neurons
Spinal Cord
Microglia
3 Citations (Scopus)
Amyotrophic Lateral Sclerosis
Neuroglia
Motor Neurons
Spinal Cord
Microglia
1 Citation (Scopus)
Vesicular Glutamate Transport Proteins
Amino Acid Transport System X-AG
Amyotrophic Lateral Sclerosis
Motor Neurons
Neuroglia
9 Citations (Scopus)

Early and extensive spinal white matter involvement in neuromyelitis optica

Hayashida, S., Masaki, K., Yonekawa, T., Suzuki, S. O., Hiwatashi, A., Matsushita, T., Watanabe, M., Yamasaki, R., Suenaga, T., Iwaki, T., Murai, H. & Kira, J. I., May 2017, In : Brain Pathology. 27, 3, p. 249-265 17 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Aquaporin 4
Spinal Cord
Horns
Antibodies
9 Citations (Scopus)
Multiple System Atrophy
Chemokines
Cerebrospinal Fluid
Case-Control Studies
Cytokines
8 Citations (Scopus)

Efficacy, safety, and pharmacokinetics of natalizumab in Japanese multiple sclerosis patients: A double-blind, randomized controlled trial and open-label pharmacokinetic study

Saida, T., Kira, J. I., Kishida, S., Yamamura, T., Sudo, Y., Ogiwara, K., Tibung, J. T., Lucas, N. & Subramanyam, M., Jan 1 2017, In : Multiple Sclerosis and Related Disorders. 11, p. 25-31 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Randomized Controlled Trials
Pharmacokinetics
Safety
Relapsing-Remitting Multiple Sclerosis
10 Citations (Scopus)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Ganglia
Brachial Plexus
Signal-To-Noise Ratio
Research Ethics Committees

Extensive white matter pathology of longitudinally extensive myelitis in neuromyelitis optica

Hayashida, S., Masaki, K. & Kira, J. I., Feb 1 2017, In : Clinical and Experimental Neuroimmunology. 8, 1, p. 9-10 2 p.

Research output: Contribution to journalComment/debate

Neuromyelitis Optica
Myelitis
Pathology
White Matter
5 Citations (Scopus)

HLA-DRB1*04:05 allele is associated with intracortical lesions on three-dimensional double inversion recovery images in Japanese patients with multiple sclerosis

Shinoda, K., Matsushita, T., Nakamura, Y., Masaki, K., Yamasaki, R., Yamaguchi, H., Togao, O., Hiwatashi, A. & Kira, J-I., May 1 2017, In : Multiple Sclerosis. p. 1352458517707067

Research output: Contribution to journalArticle

Multiple Sclerosis
Alleles
HLA-DRB1 Chains
HLA-DRB1*04 antigen
Logistic Models
3 Citations (Scopus)

Improving treatment times for patients with in-hospital stroke using a standardized protocol

Koge, J., Matsumoto, S., Nakahara, I., Ishii, A., Hatano, T., Sadamasa, N., Kai, Y., Ando, M., Saka, M., Chihara, H., Takita, W., Tokunaga, K., Kamata, T., Nishi, H., Hashimoto, T., Tsujimoto, A., Kira, J. I. & Nagata, I., Oct 15 2017, In : Journal of the Neurological Sciences. 381, p. 68-73 6 p.

Research output: Contribution to journalArticle

Stroke
Neuroimaging
Therapeutics
Intracranial Hemorrhages
Clinical Protocols
7 Citations (Scopus)

Long-term efficacy and safety of fingolimod in Japanese patients with relapsing multiple sclerosis: 3-year results of the phase 2 extension study

Saida, T., Itoyama, Y., Kikuchi, S., Hao, Q., Kurosawa, T., Ueda, K., Auberson, L. Z., Tsumiyama, I., Nagato, K. & Kira, J. I., Jan 28 2017, In : BMC neurology. 17, 1, 17.

Research output: Contribution to journalArticle

Multiple Sclerosis
Safety
Placebos
Fingolimod Hydrochloride
Recurrence
10 Citations (Scopus)
Lumbosacral Plexus
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Polyneuropathies
Ganglia
ROC Curve
Common Carotid Artery
Arteries
Middle Cerebral Artery
Internal Carotid Artery
Ultrasonography
1 Citation (Scopus)

Natalizumab for Achieving Relapse-Free, T1 Gadolinium-Enhancing-Lesion-Free, and T2 Lesion-Free Status in Japanese Multiple Sclerosis Patients: A Phase 2 Trial Subanalysis

Saida, T., Kira, J. I., Kishida, S., Yamamura, T., Ohtsuka, N., Dong, Q. & Tibung, J. T., Jun 1 2017, In : Neurology and Therapy. 6, 1, p. 153-159 7 p.

Research output: Contribution to journalArticle

Gadolinium
Multiple Sclerosis
Recurrence
Relapsing-Remitting Multiple Sclerosis
Placebos
46 Citations (Scopus)

Paranodal dissection in chronic inflammatory demyelinating polyneuropathy with anti-neurofascin-155 and anti-contactin-1 antibodies

Koike, H., Kadoya, M., Kaida, K. I., Ikeda, S., Kawagashira, Y., Iijima, M., Kato, D., Ogata, H., Yamasaki, R., Matsukawa, N., Kira, J. I., Katsuno, M. & Sobue, G., Jun 1 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 6, p. 465-473 9 p.

Research output: Contribution to journalArticle

Contactin 1
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Dissection
Antibodies
Demyelinating Diseases
1 Citation (Scopus)

q-space Myelin Map imaging: A new imaging technique for treatment evaluation in multiple sclerosis

Kira, J. I., Feb 15 2017, In : Journal of the Neurological Sciences. 373, p. 358-359 2 p.

Research output: Contribution to journalComment/debate

Questionnaire survey on the process of specialty training in neurology in Japan

Sonoo, M., Nishiyama, K., Ando, T., Shindo, K., Kanda, T., Aoki, M., Kamei, S., Kikuchi, S., Kusunoki, S., Suzuki, N., Sobue, G., Nakashima, K., Hara, H., Hirata, K., Mizusawa, H., Murai, H., Murata, M., Mochizuki, H., Takahashi, R. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 7, p. 402-410 9 p.

Research output: Contribution to journalReview article

Neurology
Japan
Internship and Residency
Urban Hospitals
Documentation
1 Citation (Scopus)

Re-emergence of a tumefactive demyelinating lesion after initiation of fingolimod therapy

Hashimoto, Y., Shinoda, K., Tanaka, E., Uehara, T., Matsushita, T., Yamasaki, R. & Kira, J. I., Aug 15 2017, In : Journal of the Neurological Sciences. 379, p. 167-168 2 p.

Research output: Contribution to journalLetter

Multiple Sclerosis
Therapeutics
Fingolimod Hydrochloride

Safety and effectiveness of interferon β-1a intramuscular therapy: results of the postmarketing drug surveillance in Japan

Makioka, H., Nakaya, F., Ling, Y., Torii, S., Saida, T. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 10, p. 553-561 9 p.

Research output: Contribution to journalArticle

Postmarketing Product Surveillance
Interferons
Japan
Safety
Recurrence
3 Citations (Scopus)

Safety and Efficacy of Natalizumab in Japanese Patients with Relapsing-Remitting Multiple Sclerosis: Open-Label Extension Study of a Phase 2 Trial

on behalf of the Natalizumab Trial Principal Investigators, Jun 1 2017, In : Neurology and Therapy. 6, 1, p. 39-55 17 p.

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
Safety
Placebos
JC Virus
Natalizumab
2 Citations (Scopus)
Pathologic Nystagmus
Smooth Pursuit
Eye Movements
Mutation
Type 2 Episodic Ataxia
2 Citations (Scopus)

Structural changes in Parkinson’s disease: voxel-based morphometry and diffusion tensor imaging analyses based on 123I-MIBG uptake

Kikuchi, K., Hiwatashi, A., Togao, O., Yamashita, K., Somehara, R., Kamei, R., Baba, S., Yamaguchi, H., Kira, J. I. & Honda, H., Dec 1 2017, In : European Radiology. 27, 12, p. 5073-5079 7 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Parkinson Disease
Mediastinum
Brain
Myocardial Perfusion Imaging

Survey of the participants of EEG teaching courses provided by Japanese Society of Neurology: Current state and gradual evolution for EEG teaching in the last 5 years

Tanioka, K., Hitomi, T., Matsumoto, R., Takahashi, R., Tobimatsu, S., Inuzuka, T., Kira, J-I., Kusunoki, S. & Ikeda, A., Jan 1 2017, In : Clinical Neurology. 57, 3, p. 110-117 8 p.

Research output: Contribution to journalArticle

Neurology
Electroencephalography
Teaching
Surveys and Questionnaires
Epilepsy
15 Citations (Scopus)
Aquaporin 4
Neuromyelitis Optica
Th17 Cells
Th2 Cells
Th1 Cells
2016
1 Citation (Scopus)

A case of cerebrotendinous xanthomatosis mimicking the clinical phenotype of mitochondrial disease with a novel frame-shift mutation (c. 43-44 delGG) in CYP27A1 gene exon 1

Koge, J., Hayashi, S., Yamaguchi, H., Tateishi, T., Murai, H. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 10, p. 667-671 5 p.

Research output: Contribution to journalArticle

Cerebrotendinous Xanthomatosis
Mitochondrial Diseases
Frameshift Mutation
MERRF Syndrome
Cholestanol
1 Citation (Scopus)

A case of paroxysmal sympathetic storm after acute disseminated encephalomyelitis and hypoxic encephalopathy responding to clonidine hydrochloride

Shimmura, M., Kawamura, N., Tateishi, T., Shigeto, H., Murai, H. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 2, p. 108-111 4 p.

Research output: Contribution to journalArticle

Acute Disseminated Encephalomyelitis
Brain Hypoxia
Clonidine
Decerebrate State
Tachypnea

A case of primary central nervous system vasculitis diagnosed by second brain biopsy and treated successfully

Mizuno, Y., Shigeto, H., Yamada, T., Maeda, N., Suzuki, S. O. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 3, p. 186-190 5 p.

Research output: Contribution to journalArticle

Central Nervous System Vasculitis
Biopsy
Brain
Frontal Lobe
Diplopia
3 Citations (Scopus)
MELAS Syndrome
Rhabdomyolysis
Status Epilepticus
Stroke
Occipital Lobe
9 Citations (Scopus)

Allergic inflammation leads to neuropathic pain via glial cell activation

Yamasaki, R., Fujii, T., Wang, B., Masaki, K., Kido, M. A., Yoshida, M., Matsushita, T. & Kira, J. I., Nov 23 2016, In : Journal of Neuroscience. 36, 47, p. 11929-11945 17 p.

Research output: Contribution to journalArticle

Endothelin B Receptors
Neuralgia
Neuroglia
Microglia
Inflammation
30 Citations (Scopus)

A nationwide survey of combined central and peripheral demyelination in Japan

Ogata, H., Matsuse, D., Yamasaki, R., Kawamura, N., Matsushita, T., Yonekawa, T., Hirotani, M., Murai, H. & Kira, J. I., Jan 1 2016, In : Journal of Neurology, Neurosurgery and Psychiatry. 87, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

Demyelinating Diseases
Japan
Oligoclonal Bands
Visual Evoked Potentials
Peripheral Nervous System
19 Citations (Scopus)

A nationwide survey of pediatric acquired demyelinating syndromes in Japan

Yamaguchi, Y., Torisu, H., Kira, R., Ishizaki, Y., Sakai, Y., Sanefuji, M., Ichiyama, T., Oka, A., Kishi, T., Kimura, S., Kubota, M., Takanashi, J., Takahashi, Y., Tamai, H., Natsume, J., Hamano, S., Hirabayashi, S., Maegaki, Y., Mizuguchi, M., Minagawa, K. & 4 others, Yoshikawa, H., Kira, J., Kusunoki, S. & Hara, T., Nov 8 2016, In : Neurology. 87, 19, p. 2006-2015 10 p.

Research output: Contribution to journalArticle

Japan
Acute Disseminated Encephalomyelitis
Neuromyelitis Optica
Pediatrics
Multiple Sclerosis
3 Citations (Scopus)

Antibodies to myelin oligodendrocyte glycoprotein are uncommon in Japanese opticospinal multiple sclerosis

Ramanathan, S., Sato, S., Matsushita, T., Masaki, K., Yamasaki, R., Dale, R. C., Kira, J. I. & Brilot, F., Jan 1 2016, In : Multiple Sclerosis. 22, 1, p. 127-128 2 p.

Research output: Contribution to journalLetter

Myelin-Oligodendrocyte Glycoprotein
Neuromyelitis Optica
Antibodies
Opticospinal Multiple Sclerosis

Antibodies to myelin oligodendrocyte glycoprotein are uncommon in Japanese opticospinal multiple sclerosis

Ramanathan, S., Sato, S., Matsushita, T., Masaki, K., Yamasaki, R., Dale, R. C., Kira, J. I. & Brilot, F., Jan 1 2016, In : Multiple Sclerosis. 22, 1, p. 127-128 2 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Neuromyelitis Optica
Autoantibodies
Multiple Sclerosis
Young Adult
8 Citations (Scopus)

A Potential VEP Biomarker for Mild Cognitive Impairment: Evidence from Selective Visual Deficit of Higher-Level Dorsal Pathway

Yamasaki, T., Horie, S., Ohyagi, Y., Tanaka, E., Nakamura, N., Goto, Y., Kanba, S., Kira, J. I., Tobimatsu, S. & Mandal, P., Jan 1 2016, In : Journal of Alzheimer's Disease. 53, 2, p. 661-676 16 p.

Research output: Contribution to journalArticle

Visual Evoked Potentials
Biomarkers
Neuropsychological Tests
ROC Curve
Optic Flow