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2014

The actual state and problems in neurology training in medical schools

Taniwaki, T., Inuzuka, T., Yoshii, F., Aoki, M., Amano, T., Toyoshima, I., Fukutake, T., Hashimoto, Y. & Kira, J. I., 2014, In : Clinical Neurology. 54, 4, p. 335-340 6 p.

Research output: Contribution to journalArticle

Neurology
Medical Schools
Education
Graduate Education
Textbooks
Multiple Sclerosis
Fingolimod Hydrochloride
Multiple Sclerosis
Central Nervous System
Lysosphingolipid Receptors
Lymphocytes
Spinal Cord
2015
2 Citations (Scopus)

A case of central pontine myelinolysis caused by hypophosphatemia secondary to refeeding syndrome

Yamashita, C., Shigeto, H., Maeda, N., Torii, T., Ohyagi, Y. & Kira, J. I., Jan 1 2015, In : Case Reports in Neurology. 7, 3, p. 196-203 8 p.

Research output: Contribution to journalArticle

Refeeding Syndrome
Central Pontine Myelinolysis
Hypophosphatemia
Hyponatremia
Serum
1 Citation (Scopus)

A case of chronic progressive motor-dominant multiple mononeuritis associated with primary Sjögren's syndrome

Saitoh, B. Y., Hayashi, S., Kamada, T., Murai, H., Omoto, M. & Kira, J. I., Jan 1 2015, In : Clinical Neurology. 55, 10, p. 753-758 6 p.

Research output: Contribution to journalArticle

Mononeuropathies
Oligoclonal Bands
Leg
Paresthesia
Immunoglobulin G
3 Citations (Scopus)

A case of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome presenting with hypertrophic pachymeningitis

Shiraishi, W., Hayashi, S., Iwanaga, Y., Murai, H., Yamamoto, A. & Kira, J. I., Feb 15 2015, In : Journal of the Neurological Sciences. 349, 1-2, p. 229-231 3 p.

Research output: Contribution to journalArticle

Hyperostosis
Osteitis
Synovitis
Acne Vulgaris
Meningitis
11 Citations (Scopus)

Analysis of cerebral lobar microbleeds and a decreased cerebral blood flow in a memory clinic setting

Doi, H., Inamizu, S., Saito, B. Y., Murai, H., Araki, T. & Kira, J. I., Jan 1 2015, In : Internal Medicine. 54, 9, p. 1027-1033 7 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Occipital Lobe
Parietal Lobe
Brain
Frontal Lobe

Background and trigger factors for neuroimmunological diseases

Kira, J. I., Sep 1 2015, In : Nihon rinsho. Japanese journal of clinical medicine. 73, p. 13-22 10 p.

Research output: Contribution to journalArticle

Autoimmune Diseases of the Nervous System
Feeding Behavior
Genetic Predisposition to Disease
HLA Antigens
Autoimmunity

Baló's disease (concentric sclerosis)

Masaki, K. & Kira, J. I., Sep 1 2015, In : Nihon rinsho. Japanese journal of clinical medicine. 73, p. 320-326 7 p.

Research output: Contribution to journalArticle

Diffuse Cerebral Sclerosis of Schilder
Multiple Sclerosis
Differential Diagnosis
Macrophages
Magnetic Resonance Imaging
17 Citations (Scopus)

Body weight-based natalizumab treatment in adult patients with multiple sclerosis

Tanaka, M., Kinoshita, M., Foley, J. F., Tanaka, K., Kira, J. & Carroll, W. M., Mar 18 2015, In : Journal of Neurology. 262, 3, p. 781-782 2 p.

Research output: Contribution to journalLetter

Immunologic Factors
Multiple Sclerosis
Body Weight
Therapeutics
Natalizumab
11 Citations (Scopus)

CD30 ligand is a new therapeutic target for central nervous system autoimmunity

Shinoda, K., Sun, X., Oyamada, A., Yamada, H., Muta, H., Podack, E. R., Kira, J. I. & Yoshikai, Y., Feb 1 2015, In : Journal of Autoimmunity. 57, p. 14-23 10 p.

Research output: Contribution to journalArticle

CD30 Ligand
Autoimmunity
Central Nervous System
Th17 Cells
Th1 Cells
Early Medical Intervention
Age Distribution
Vitamin D
Multiple Sclerosis
Japan
61 Citations (Scopus)

Characterization of IgG4 anti-neurofascin 155 antibody-positive polyneuropathy

Ogata, H., Yamasaki, R., Hiwatashi, A., Oka, N., Kawamura, N., Matsuse, D., Kuwahara, M., Suzuki, H., Kusunoki, S., Fujimoto, Y., Ikezoe, K., Kishida, H., Tanaka, F., Matsushita, T., Murai, H. & Kira, J. I., Oct 2015, In : Annals of Clinical and Translational Neurology. 2, 10, p. 960-971 12 p.

Research output: Contribution to journalArticle

Polyneuropathies
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Immunoglobulin G
Antibodies
Hypertrophy
7 Citations (Scopus)

Copy number variations in multiple sclerosis and neuromyelitis optica

Sato, S., Yamamoto, K., Matsushita, T., Isobe, N., Kawano, Y., Iinuma, K., Niino, M., Fukazawa, T., Nakamura, Y., Watanabe, M., Yonekawa, T., Masaki, K., Yoshimura, S., Murai, H., Yamasaki, R. & Kira, J. I., Nov 2015, In : Annals of Neurology. 78, 5, p. 762-774 13 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Multiple Sclerosis
T-Cell Antigen Receptor
Odds Ratio
Aquaporin 4
23 Citations (Scopus)

Decreased serum vitamin D levels in Japanese patients with multiple sclerosis

Niino, M., Sato, S., Fukazawa, T., Masaki, K., Miyazaki, Y., Matsuse, D., Yamasaki, R., Takahashi, E., Kikuchi, S. & Kira, J. I., Jan 1 2015, In : Journal of Neuroimmunology. 279, C, p. 40-45 6 p.

Research output: Contribution to journalArticle

Vitamin D
Multiple Sclerosis
Serum
Japan
Vitamin D-Binding Protein
1 Citation (Scopus)

Distinct features of immunoglobulin G2 aquaporin-4 antibody carriers with neuromyelitis optica

Isobe, N., Yonekawa, T., Matsushita, T., Kawano, Y., Masaki, K., Yoshimura, S., Murai, H., Yamasaki, R. & Kira, J-I., May 1 2015, In : Clinical and Experimental Neuroimmunology. 6, 2, p. 154-158 5 p.

Research output: Contribution to journalArticle

Aquaporin 4
Neuromyelitis Optica
Immunoglobulins
Antibodies
Immunoglobulin G
6 Citations (Scopus)

Galectin-1 deficiency improves axonal swelling of motor neurones in SOD1G93A transgenic mice

Kobayakawa, Y., Sakumi, K., Kajitani, K., Kadoya, T., Horie, H., Kira, J. I. & Nakabeppu, Y., Feb 1 2015, In : Neuropathology and Applied Neurobiology. 41, 2, p. 227-244 18 p.

Research output: Contribution to journalArticle

Galectin 1
Motor Neurons
Transgenic Mice
Amyotrophic Lateral Sclerosis
Axons
4 Citations (Scopus)

Helicobacter pylori infection might prove the hygiene hypothesis in multiple sclerosis

Kira, J. I., Jun 1 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 6, p. 591-592 2 p.

Research output: Contribution to journalComment/debate

Infection
Hygiene
Multiple Sclerosis
Neuromyelitis Optica
Spinal Cord
White Matter
11 Citations (Scopus)

Japanese POEMS syndrome with thalidomide ( J-POST) trial: Study protocol for a phase II/III multicentre, randomised, double-blind, placebo-controlled trial

Katayama, K., Misawa, S., Sato, Y., Sobue, G., Yabe, I., Watanabe, O., Nishizawa, M., Kusunoki, S., Kikuchi, S., Nakashima, I., Ikeda, S. I., Kohara, N., Kanda, T., Kira, J. I., Hanaoka, H. & Kuwabara, S., 2015, In : BMJ open. 5, 1, e007330.

Research output: Contribution to journalArticle

POEMS Syndrome
Thalidomide
Clinical Protocols
Placebos
Safety

Japan MG Registry Study: A Sophisti- cated Multi-center Study of Myasthe- nia Gravis A sophisticated multi-center Study of Myasthenia Gravis

Murai, H., Utsugisawa, K., Suzuki, S., Nagane, Y., Imai, T., Motomura, M. & Kira, J. I., Dec 1 2015, In : Fukuoka igaku zasshi = Hukuoka acta medica. 106, 12, p. 309-315 7 p.

Research output: Contribution to journalReview article

Early Medical Intervention
Myasthenia Gravis
Registries
Japan
Quality of Life
8 Citations (Scopus)

Latitude and HLA-DRB1 alleles independently affect the emergence of cerebrospinal fluid IgG abnormality in multiple sclerosis

Niino, M., Sato, S., Fukazawa, T., Yoshimura, S., Hisahara, S., Matsushita, T., Isobe, N., Yoshida, K., Houzen, H., Miyazaki, Y., Shimohama, S., Kikuchi, S. & Kira, J. I., Aug 25 2015, In : Multiple Sclerosis. 21, 9, p. 1112-1120 9 p.

Research output: Contribution to journalArticle

Oligoclonal Bands
HLA-DRB1 Chains
Multiple Sclerosis
Cerebrospinal Fluid
Immunoglobulin G

Multimodal diagnostic approach for limbic encephalitis associated with antivoltage-gated potassium channel complex antibodies

Mukaino, T., Shiraishi, W., Kamada, T., Uehara, T., Yamaguchi, H., Shigeto, H., Akutagawa, N., Yoshimura, T., Murai, H. & Kira, J. I., Aug 1 2015, In : Clinical and Experimental Neuroimmunology. 6, 3, p. 318-320 3 p.

Research output: Contribution to journalArticle

Limbic Encephalitis
Potassium Channels
Antibodies
3 Citations (Scopus)

Multiphasic acute disseminated encephalomyelitis associated with atypical rubella virus infection

Shinoda, K., Asahara, H., Uehara, T., Miyoshi, K., Suzuki, S. O., Iwaki, T. & Kira, J. I., Feb 17 2015, In : Multiple Sclerosis Journal. 21, 2, p. 252-254 3 p.

Research output: Contribution to journalLetter

Acute Disseminated Encephalomyelitis
Rubella virus
Rubella
Virus Diseases
Passive Immunization
Acute Disseminated Encephalomyelitis
Rubella virus
Rubella
Virus Diseases
1 Citation (Scopus)
Demyelinating Diseases
Surveys and Questionnaires
13 Citations (Scopus)

Necklace cytoplasmic bodies in hereditary myopathy with early respiratory failure

Uruha, A., Hayashi, Y. K., Oya, Y., Mori-Yoshimura, M., Kanai, M., Murata, M., Kawamura, M., Ogata, K., Matsumura, T., Suzuki, S., Takahashi, Y., Kondo, T., Kawarabayashi, T., Ishii, Y., Kokubun, N., Yokoi, S., Yasuda, R., Kira, J. I., Mitsuhashi, S., Noguchi, S. & 2 others, Nonaka, I. & Nishino, I., May 1 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 5, p. 483-489 7 p.

Research output: Contribution to journalArticle

Fibronectins
Muscles
Pathology
Sensitivity and Specificity
Muscular Diseases

Neuropathology of multiple sclerosis

Masaki, K. & Kira, J. I., Sep 1 2015, In : Nihon rinsho. Japanese journal of clinical medicine. 73, p. 141-149 9 p.

Research output: Contribution to journalArticle

Acute Disease
Meningitis
Multiple Sclerosis
Disease Progression
Chronic Disease
5 Citations (Scopus)

Outcomes of pregnancy during interferon beta-1a therapy in Japanese patients with multiple sclerosis: Interim results of a postmarketing surveillance study

Shimizu, Y., Makioka, H., Harada, N., Nakabayashi, S., Saida, T. & Kira, J-I., Nov 1 2015, In : Clinical and Experimental Neuroimmunology. 6, 4, p. 402-408 7 p.

Research output: Contribution to journalArticle

Pregnancy Outcome
Multiple Sclerosis
Recurrence
Postpartum Period
Pregnancy
Central Nervous System Diseases
Demyelinating Diseases
Peripheral Nervous System Diseases
Multiple Sclerosis
Pathology
39 Citations (Scopus)

Peripheral blood T cell dynamics predict relapse in multiple sclerosis patients on fingolimod

Song, Z. Y., Yamasaki, R., Kawano, Y., Sato, S., Masaki, K., Yoshimura, S., Matsuse, D., Murai, H., Matsushita, T. & Kira, J. I., Apr 28 2015, In : PloS one. 10, 4, e0124923.

Research output: Contribution to journalArticle

T-cells
relapse
sclerosis
blood cells
Multiple Sclerosis
20 Citations (Scopus)

Pre-admission CHADS2, CHA2DS2-VASc, and R2CHADS2 scores on severity and functional outcome in acute ischemic stroke with atrial fibrillation

Tanaka, K., Yamada, T., Torii, T., Furuta, K., Matsumoto, S., Yoshimura, T., Takase, K. I., Wakata, Y., Nakashima, N., Kira, J. I. & Murai, H., Jul 1 2015, In : Journal of Stroke and Cerebrovascular Diseases. 24, 7, p. 1629-1635 7 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Stroke
ROC Curve
National Institutes of Health (U.S.)
Area Under Curve
2 Citations (Scopus)

Pure dysarthria and dysarthria-facial paresis syndrome due to internal capsule and/or corona radiata infarction

Tanaka, K., Yamada, T., Torii, T., Yoshimura, T., Takase, K. I., Togao, O., Wakata, Y., Hiwatashi, A., Nakashima, N., Kira, J. I. & Murai, H., Oct 7 2015, In : BMC neurology. 15, 1, 184.

Research output: Contribution to journalArticle

Internal Capsule
Dysarthria
Facial Paralysis
Infarction
Stroke

Tumefactive multiple sclerosis and connexin

Masaki, K. & Kira, J. I., Sep 1 2015, In : Nihon rinsho. Japanese journal of clinical medicine. 73, p. 826-834 9 p.

Research output: Contribution to journalArticle

Connexins
Gap Junctions
Cell Communication
Neuroglia
Multiple Sclerosis
2016
1 Citation (Scopus)

A case of cerebrotendinous xanthomatosis mimicking the clinical phenotype of mitochondrial disease with a novel frame-shift mutation (c. 43-44 delGG) in CYP27A1 gene exon 1

Koge, J., Hayashi, S., Yamaguchi, H., Tateishi, T., Murai, H. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 10, p. 667-671 5 p.

Research output: Contribution to journalArticle

Cerebrotendinous Xanthomatosis
Mitochondrial Diseases
Frameshift Mutation
MERRF Syndrome
Cholestanol
1 Citation (Scopus)

A case of paroxysmal sympathetic storm after acute disseminated encephalomyelitis and hypoxic encephalopathy responding to clonidine hydrochloride

Shimmura, M., Kawamura, N., Tateishi, T., Shigeto, H., Murai, H. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 2, p. 108-111 4 p.

Research output: Contribution to journalArticle

Acute Disseminated Encephalomyelitis
Brain Hypoxia
Clonidine
Decerebrate State
Tachypnea

A case of primary central nervous system vasculitis diagnosed by second brain biopsy and treated successfully

Mizuno, Y., Shigeto, H., Yamada, T., Maeda, N., Suzuki, S. O. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 3, p. 186-190 5 p.

Research output: Contribution to journalArticle

Central Nervous System Vasculitis
Biopsy
Brain
Frontal Lobe
Diplopia
3 Citations (Scopus)
MELAS Syndrome
Rhabdomyolysis
Status Epilepticus
Stroke
Occipital Lobe
10 Citations (Scopus)

Allergic inflammation leads to neuropathic pain via glial cell activation

Yamasaki, R., Fujii, T., Wang, B., Masaki, K., Kido, M. A., Yoshida, M., Matsushita, T. & Kira, J. I., Nov 23 2016, In : Journal of Neuroscience. 36, 47, p. 11929-11945 17 p.

Research output: Contribution to journalArticle

Endothelin B Receptors
Neuralgia
Neuroglia
Microglia
Inflammation
31 Citations (Scopus)

A nationwide survey of combined central and peripheral demyelination in Japan

Ogata, H., Matsuse, D., Yamasaki, R., Kawamura, N., Matsushita, T., Yonekawa, T., Hirotani, M., Murai, H. & Kira, J. I., Jan 1 2016, In : Journal of Neurology, Neurosurgery and Psychiatry. 87, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

Demyelinating Diseases
Japan
Oligoclonal Bands
Visual Evoked Potentials
Peripheral Nervous System
19 Citations (Scopus)

A nationwide survey of pediatric acquired demyelinating syndromes in Japan

Yamaguchi, Y., Torisu, H., Kira, R., Ishizaki, Y., Sakai, Y., Sanefuji, M., Ichiyama, T., Oka, A., Kishi, T., Kimura, S., Kubota, M., Takanashi, J., Takahashi, Y., Tamai, H., Natsume, J., Hamano, S., Hirabayashi, S., Maegaki, Y., Mizuguchi, M., Minagawa, K. & 4 others, Yoshikawa, H., Kira, J., Kusunoki, S. & Hara, T., Nov 8 2016, In : Neurology. 87, 19, p. 2006-2015 10 p.

Research output: Contribution to journalArticle

Japan
Acute Disseminated Encephalomyelitis
Neuromyelitis Optica
Pediatrics
Multiple Sclerosis
3 Citations (Scopus)

Antibodies to myelin oligodendrocyte glycoprotein are uncommon in Japanese opticospinal multiple sclerosis

Ramanathan, S., Sato, S., Matsushita, T., Masaki, K., Yamasaki, R., Dale, R. C., Kira, J. I. & Brilot, F., Jan 1 2016, In : Multiple Sclerosis. 22, 1, p. 127-128 2 p.

Research output: Contribution to journalLetter

Myelin-Oligodendrocyte Glycoprotein
Neuromyelitis Optica
Antibodies
Opticospinal Multiple Sclerosis

Antibodies to myelin oligodendrocyte glycoprotein are uncommon in Japanese opticospinal multiple sclerosis

Ramanathan, S., Sato, S., Matsushita, T., Masaki, K., Yamasaki, R., Dale, R. C., Kira, J. I. & Brilot, F., Jan 1 2016, In : Multiple Sclerosis. 22, 1, p. 127-128 2 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Neuromyelitis Optica
Autoantibodies
Multiple Sclerosis
Young Adult
8 Citations (Scopus)

A Potential VEP Biomarker for Mild Cognitive Impairment: Evidence from Selective Visual Deficit of Higher-Level Dorsal Pathway

Yamasaki, T., Horie, S., Ohyagi, Y., Tanaka, E., Nakamura, N., Goto, Y., Kanba, S., Kira, J. I., Tobimatsu, S. & Mandal, P., Jan 1 2016, In : Journal of Alzheimer's Disease. 53, 2, p. 661-676 16 p.

Research output: Contribution to journalArticle

Visual Evoked Potentials
Biomarkers
Neuropsychological Tests
ROC Curve
Optic Flow
7 Citations (Scopus)

Chondroitin sulfate β-1,4-N-acetylgalactosaminyltransferase-1 (ChGn-1) polymorphism: Association with progression of multiple sclerosis

Saigoh, K., Yoshimura, S., Izumikawa, T., Miyata, S., Tabara, Y., Matsushita, T., Miki, T., Miyamoto, K., Hirano, M., Kitagawa, H., Kira, J. I. & Kusunoki, S., Jul 1 2016, In : Neuroscience Research. 108, p. 55-59 5 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Chondroitin Sulfate Proteoglycans
Single Nucleotide Polymorphism
Central Nervous System
Genes

Dermatomyositis complicated with asymmetric peripheral neuritis on exacerbation: A case report and literature review

Irie, T., Shigeto, H., Koge, J., Yamaguchi, H., Murai, H. & Kira, J. I., Nov 1 2016, In : Clinical and Experimental Neuroimmunology. 7, 4, p. 373-380 8 p.

Research output: Contribution to journalArticle

Neuritis
Dermatomyositis
Mononeuropathies
Peroneal Nerve
Muscle Weakness
15 Citations (Scopus)

Efficacy of intravenous methylprednisolone pulse therapy in patients with multiple sclerosis and neuromyelitis optica

Yamasaki, R., Matsushita, T., Fukazawa, T., Yokoyama, K., Fujihara, K., Ogino, M., Yokota, T., Miyamoto, K., Niino, M., Nomura, K., Tomioka, R., Tanaka, M., Kawachi, I., Ohashi, T., Kaida, K. I., Matsui, M., Nakatsuji, Y., Ochi, H., Fukaura, H., Kanda, T. & 5 others, Nagaishi, A., Togo, K., Mizusawa, H., Murai, H. & Kira, J. I., Sep 1 2016, In : Multiple Sclerosis. 22, 10, p. 1337-1348 12 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Methylprednisolone
Multiple Sclerosis
Therapeutics
Signs and Symptoms
45 Citations (Scopus)

Histopathologic Analysis of Retrieved Thrombi Associated with Successful Reperfusion after Acute Stroke Thrombectomy

Hashimoto, T., Hayakawa, M., Funatsu, N., Yamagami, H., Satow, T., Takahashi, J. C., Nagatsuka, K., Ishibashi-Ueda, H., Kira, J. I. & Toyoda, K., Dec 1 2016, In : Stroke. 47, 12, p. 3035-3037 3 p.

Research output: Contribution to journalArticle

Thrombectomy
Reperfusion
Thrombosis
Stroke
Erythrocytes