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2019

A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient

Hayashi, N., Kuroda, Y., Saito, T., Tsuruda, Y., Niida, A., Otsu, H., Eguchi, H., Masuda, T., Suzuki, Y., Natsugoe, S. & Mimori, K., Sep 10 2019, In : Surgery today. 49, 9, p. 738-747 10 p.

Research output: Contribution to journalArticle

Clinical Trials
Neoplasms
Constitution and Bylaws
Mutation
Molecular Targeted Therapy
48 Citations (Scopus)

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

Yokoyama, A., Kakiuchi, N., Yoshizato, T., Nannya, Y., Suzuki, H., Takeuchi, Y., Shiozawa, Y., Sato, Y., Aoki, K., Kim, S. K., Fujii, Y., Yoshida, K., Kataoka, K., Nakagawa, M. M., Inoue, Y., Hirano, T., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M. & 20 others, Nishikawa, Y., Amanuma, Y., Ohashi, S., Aoyama, I., Horimatsu, T., Miyamoto, S., Tsunoda, S., Sakai, Y., Narahara, M., Brown, J. B., Sato, Y., Sawada, G., Mimori, K., Minamiguchi, S., Haga, H., Seno, H., Miyano, S., Makishima, H., Muto, M. & Ogawa, S., Jan 17 2019, In : Nature. 565, 7739, p. 312-317 6 p.

Research output: Contribution to journalArticle

Epithelium
Mutation
Clone Cells
Neoplasms
Smoking

ASO Author Reflections: ARL4C and Peritoneal Dissemination in Gastric Cancer

Hu, Q. & Mimori, K., Dec 1 2019, In : Annals of Surgical Oncology. 26, 1 p.

Research output: Contribution to journalComment/debate

Stomach Neoplasms
2 Citations (Scopus)

Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens

Kohsaka, S., Tatsuno, K., Ueno, T., Nagano, M., Shinozaki-Ushiku, A., Ushiku, T., Takai, D., Ikegami, M., Kobayashi, H., Kage, H., Ando, M., Hata, K., Ueda, H., Yamamoto, S., Kojima, S., Oseto, K., Akaike, K., Suehara, Y., Hayashi, T., Saito, T. & 19 others, Takahashi, F., Takahashi, K., Takamochi, K., Suzuki, K., Nagayama, S., Oda, Y., Mimori, K., Ishihara, S., Yatomi, Y., Nagase, T., Nakajima, J., Tanaka, S., Fukayama, M., Oda, K., Nangaku, M., Miyazono, K., Miyagawa, K., Aburatani, H. & Mano, H., Apr 2019, In : Cancer Science. 110, 4, p. 1464-1479 16 p.

Research output: Contribution to journalArticle

Open Access
Paraffin
Formaldehyde
RNA
Neoplasms
Microsatellite Instability

CRMP5-associated GTPase (CRAG) Is a candidate driver gene for colorectal cancer carcinogenesis

Shimizu, D., Masuda, T., Sato, K., Tsuruda, Y., otsu, H., Kuroda, Y., Eguchi, H., Kodera, Y. & Mimori, K., Jan 1 2019, In : Anticancer research. 39, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Colorectal Neoplasms
Carcinogenesis
Genes
Atlases
2 Citations (Scopus)

Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis

Muto, Y., Moroishi, T., Ichihara, K., Nishiyama, M., Shimizu, H., Eguchi, H., Moriya, K., Koike, K., Mimori, K., Mori, M., Katayama, Y. & Nakayama, K. I., Apr 1 2019, In : Journal of Experimental Medicine. 216, 4, p. 950-965 16 p.

Research output: Contribution to journalArticle

Open Access
Carcinogenesis
Homeostasis
Iron
Iron Overload
Liver
1 Citation (Scopus)

Distinct methylation levels of mature microRNAs in gastrointestinal cancers

Konno, M., Koseki, J., Asai, A., Yamagata, A., Shimamura, T., Motooka, D., Okuzaki, D., Kawamoto, K., Mizushima, T., Eguchi, H., Takiguchi, S., Satoh, T., Mimori, K., Ochiya, T., Doki, Y., Ofusa, K., Mori, M. & Ishii, H., Dec 1 2019, In : Nature communications. 10, 1, 3888.

Research output: Contribution to journalArticle

Open Access
methylation
Gastrointestinal Neoplasms
Methylation
MicroRNAs
cancer
3 Citations (Scopus)

MiR-221 targets QKI to enhance the tumorigenic capacity of human colorectal cancer stem cells

Mukohyama, J., Isobe, T., Hu, Q., Hayashi, T., Watanabe, T., Maeda, M., Yanagi, H., Qian, X., Yamashita, K., Minami, H., Mimori, K., Sahoo, D., Kakeji, Y., Suzuki, A., Dalerba, P. & Shimono, Y., Oct 15 2019, In : Cancer Research. 79, 20, p. 5151-5158 8 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Colorectal Neoplasms
Organoids
MicroRNAs
Heterografts
1 Citation (Scopus)

Multiregion genomic analysis of serially transplanted patient-derived xenograft tumors

Sato, K., Niida, A., Masuda, T., Shimizu, D., Tobo, T., Kuroda, Y., Eguchi, H., Nakagawa, T., Suzuki, Y. & Mimori, K., Jan 1 2019, In : Cancer Genomics and Proteomics. 16, 1, p. 21-27 7 p.

Research output: Contribution to journalArticle

Heterografts
Tumors
Colorectal Neoplasms
Neoplasms
Exome
2 Citations (Scopus)

Novel oncogene 5MP1 reprograms c-Myc translation initiation to drive malignant phenotypes in colorectal cancer

Sato, K., Masuda, T., Hu, Q., Tobo, T., Gillaspie, S., Niida, A., Thornton, M., Kuroda, Y., Eguchi, H., Nakagawa, T., Asano, K. & Mimori, K., Jun 2019, In : EBioMedicine. 44, p. 387-402 16 p.

Research output: Contribution to journalArticle

Open Access
Oncogenes
Tumors
Colorectal Neoplasms
Protein Isoforms
Phenotype
1 Citation (Scopus)

Oncogenic splicing abnormalities induced by DEAD-Box Helicase 56 amplification in colorectal cancer

Kouyama, Y., Masuda, T., Fujii, A., Ogawa, Y., Sato, K., Tobo, T., Wakiyama, H., Yoshikawa, Y., Noda, M., Tsuruda, Y., Kuroda, Y., Eguchi, H., Ishida, F., Kudo, S. E. & Mimori, K., Oct 1 2019, In : Cancer Science. 110, 10, p. 3132-3144 13 p.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Dichlorodiphenyl Dichloroethylene
Alternative Splicing
Oncogenes
Neoplasms
1 Citation (Scopus)

Plastin3 is associated with epithelial-mesenchymal transition and poor prognosis in gastric cancer

Kurashige, J., Yokobori, T., Mima, K., Sawada, G., Takahashi, Y., Ueo, H., Takano, Y., Matsumura, T. A. E., Uchi, R., Eguchi, H., Sudo, T., Sugimachi, K., Mori, M., Baba, H. & Mimori, K., Feb 2019, In : Oncology Letters. 17, 2, p. 2393-2399 7 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Stomach Neoplasms
Cell Movement
Actins
Neoplasms
1 Citation (Scopus)

Potentials of C-C motif chemokine 2–C-C chemokine receptor type 2 blockers including propagermanium as anticancer agents

Yumimoto, K., Sugiyama, S., Mimori, K. & Nakayama, K. I., Jul 2019, In : Cancer Science. 110, 7, p. 2090-2099 10 p.

Research output: Contribution to journalReview article

Open Access
C Chemokines
CC Chemokines
Chemokine Receptors
Antineoplastic Agents
Inflammation
2017
4 Citations (Scopus)

Altered Expression of Hippo Signaling Pathway Molecules in Intrahepatic Cholangiocarcinoma

Sugimachi, K., Nishio, M., Aishima, S., Kuroda, Y., Iguchi, T., Komatsu, H., Hirata, H., Sakimura, S., Eguchi, H., Bekki, Y., Takenaka, K., Maehara, Y., Suzuki, A. & Mimori, K., Jul 1 2017, In : Oncology (Switzerland). 93, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Proteins
Knockout Mice
Multivariate Analysis
Cell Proliferation
5 Citations (Scopus)

Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer

Nambara, S., Masuda, T., Nishio, M., Kuramitsu, S., Tobo, T., Ogawa, Y., Hu, Q., Iguchi, T., Kuroda, Y., Ito, S., Eguchi, H., Sugimachi, K., Saeki, H., Oki, E., Maehara, Y., Suzuki, A. & Mimori, K., Jan 1 2017, In : Oncotarget. 8, 64, p. 107666-107677 12 p.

Research output: Contribution to journalArticle

Antiparasitic Agents
Ivermectin
Stomach Neoplasms
Proteins
Heterografts

As a Novel Prognostic Marker, Cysteine/histidine-rich 1 (CYHR1) is a Therapeutic Target in Patients with Esophageal Squamous Cell Carcinoma

Desaki, R., Sawada, G., Okumura, H., Ikeda, R., Tanabe, K., Komatsu, H., Mimori, K., Mori, M., Kita, Y., Uchikado, Y., Arigami, T., Uenosono, Y., Owaki, T., Ishigami, S. & Natsugoe, S., Feb 1 2017, In : Annals of Surgical Oncology. 24, 2, p. 586-593 8 p.

Research output: Contribution to journalArticle

Histidine
Cysteine
Therapeutics
Galectin 3
Esophageal Squamous Cell Carcinoma
6 Citations (Scopus)

Attenuated RND1 Expression Confers Malignant Phenotype and Predicts Poor Prognosis in Hepatocellular Carcinoma

Komatsu, H., Iguchi, T., Masuda, T., Hirata, H., Ueda, M., Kidogami, S., Ogawa, Y., Sato, K., Hu, Q., Nambara, S., Saito, T., Sakimura, S., Uchi, R., Ito, S., Eguchi, H., Sugimachi, K., Eguchi, H., Doki, Y., Mori, M. & Mimori, K., Mar 1 2017, In : Annals of Surgical Oncology. 24, 3, p. 850-859 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Phenotype
Survival
Atlases
Neoplasms
26 Citations (Scopus)

Circulating exosomal microRNA-203 is associated with metastasis possibly via inducing tumor-associated macrophages in colorectal cancer

Takano, Y., Masuda, T., Iinuma, H., Yamaguchi, R., Sato, K., Tobo, T., Hirata, H., Kuroda, Y., Nambara, S., Hayashi, N., Iguchi, T., Ito, S., Eguchi, H., Ochiya, T., Yanaga, K., Miyano, S. & Mimori, K., Jan 1 2017, In : Oncotarget. 8, 45, p. 78598-78613 16 p.

Research output: Contribution to journalArticle

MicroRNAs
Colorectal Neoplasms
Macrophages
Neoplasm Metastasis
Neoplasms
16 Citations (Scopus)

Clinical Impact of Tumor-Infiltrating Lymphocytes in Esophageal Squamous Cell Carcinoma

Sudo, T., Nishida, R., Kawahara, A., Saisho, K., Mimori, K., Yamada, A., Mizoguchi, A., Kadoya, K., Matono, S., Mori, N., Tanaka, T. & Akagi, Y., Nov 1 2017, In : Annals of Surgical Oncology. 24, 12, p. 3763-3770 8 p.

Research output: Contribution to journalArticle

Tumor-Infiltrating Lymphocytes
Neoplasms
Survival
Esophageal Squamous Cell Carcinoma
3 Citations (Scopus)

Clinical significance of fancd2 gene expression and its association with tumor progression in hepatocellular carcinoma

Komatsu, H., Masuda, T., Iguchi, T., Nambara, S., Sato, K., Hu, Q., Hirata, H., Ito, S., Eguchi, H., Sugimachi, K., Doki, Y., Mori, M. & Mimori, K., Mar 2017, In : Anticancer research. 37, 3, p. 1083-1090 8 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Hepatocellular Carcinoma
Gene Expression
Neoplasms
Sirolimus
2 Citations (Scopus)

Clinical significance of ZNF750 gene expression, a novel tumor suppressor gene, in esophageal squamous cell carcinoma

Nambara, S., Masuda, T., Tobo, T., Kidogami, S., Komatsu, H., Sugimachi, K., Saeki, H., Oki, E., Maehara, Y. & Mimori, K., Jan 1 2017, In : Oncology Letters. 14, 2, p. 1795-1801 7 p.

Research output: Contribution to journalArticle

Zinc Fingers
Tumor Suppressor Genes
Gene Expression
Proteins
Encyclopedias
8 Citations (Scopus)

DDR2 expression is associated with a high frequency of peritoneal dissemination and poor prognosis in colorectal cancer

Sasaki, S., Ueda, M., Iguchi, T., Kaneko, M., Nakayama, H., Watanabe, T., Sakamoto, A. & Mimori, K., May 2017, In : Anticancer research. 37, 5, p. 2587-2591 5 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Stomach Neoplasms
Biomarkers
Lymph Nodes
Immunohistochemistry

Diagnostic laparoscopy for pneumatosis intestinalis in a very elderly patient: A case report

Ito, S., Masuda, T., Harada, N., Matsuyama, A., Hamatake, M., Maeda, T., Tsutsui, S., Matsuda, H., Mimori, K. & Ishida, T., Sep 1 2017, In : Annals of Medicine and Surgery. 21, p. 109-113 5 p.

Research output: Contribution to journalArticle

Laparoscopy
Emergencies
Air
Frail Elderly
Systemic Inflammatory Response Syndrome
2 Citations (Scopus)

Downregulation of ST6GALNAC1 is associated with esophageal squamous cell carcinoma development

Iwaya, T., Sawada, G., Amano, S., Kume, K., Ito, C., Endo, F., Konosu, M., Shioi, Y., Akiyama, Y., Takahara, T., Otsuka, K., Nitta, H., Koeda, K., Mizuno, M., Nishizuka, S., Sasaki, A. & Mimori, K., Feb 2017, In : International journal of oncology. 50, 2, p. 441-447 7 p.

Research output: Contribution to journalArticle

Down-Regulation
Loss of Heterozygosity
Keratoderma, Palmoplantar, Diffuse
Methylation
Genes
1 Citation (Scopus)

Erratum: Correction: Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution (PLoS genetics (2016) 12 2 (e1005778))

Uchi, R., Takahashi, Y., Niida, A., Shimamura, T., Hirata, H., Sugimachi, K., Sawada, G., Iwaya, T., Kurashige, J., Shinden, Y., Iguchi, T., Eguchi, H., Chiba, K., Shiraishi, Y., Nagae, G., Yoshida, K., Nagata, Y., Haeno, H., Yamamoto, H., Ishii, H. & 21 others, Doki, Y., Iinuma, H., Sasaki, S., Nagayama, S., Yamada, K., Yachida, S., Kato, M., Shibata, T., Oki, E., Saeki, H., Shirabe, K., Oda, Y., Maehara, Y., Komune, S., Mori, M., Suzuki, Y., Yamamoto, K., Aburatani, H., Ogawa, S., Miyano, S. & Mimori, K., May 1 2017, In : PLoS genetics. 13, 5, p. e1006798

Research output: Contribution to journalComment/debate

Open Access
Molecular Evolution
colorectal neoplasms
Colorectal Neoplasms
cancer
Demography
2 Citations (Scopus)

Extraction of cell-free DNA from urine, using polylysine-coated silica particles

Takano, S., Hu, Q., Amamoto, T., Refinetti, P., Mimori, K., Funatsu, T. & Kato, M., Jun 1 2017, In : Analytical and Bioanalytical Chemistry. 409, 16, p. 4021-4025 5 p.

Research output: Contribution to journalArticle

Polylysine
Silicon Dioxide
Urine
DNA
Inborn Genetic Diseases
2 Citations (Scopus)

Japanese genome-wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p14

Takahashi, Y., Sugimachi, K., Yamamoto, K., Niida, A., Shimamura, T., Sato, T., Watanabe, M., Tanaka, J., Kudo, S., Sugihara, K., Hase, K., Kusunoki, M., Yamada, K., Shimada, Y., Moriya, Y., Suzuki, Y., Miyano, S., Mori, M. & Mimori, K., Nov 2017, In : Cancer Science. 108, 11, p. 2239-2247 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Colorectal Neoplasms
Chromosomes
Single Nucleotide Polymorphism
Disease Susceptibility
3 Citations (Scopus)

Long-term outcome of adipose-derived regenerative cell-enriched autologous fat transplantation for reconstruction after breast-conserving surgery for Japanese women with breast cancer

Ito, S., Kai, Y., Masuda, T., Tanaka, F., Matsumoto, T., Kamohara, Y., Hayakawa, H., Ueo, H., Iwaguro, H., Hedrick, M. H., Mimori, K. & Mori, M., Dec 1 2017, In : Surgery today. 47, 12, p. 1500-1511 12 p.

Research output: Contribution to journalArticle

Segmental Mastectomy
Autologous Transplantation
Fats
Breast Neoplasms
Adjuvant Radiotherapy
2 Citations (Scopus)

MicroRNA in various aspects of cancer development

Nambara, S. & Mimori, K., May 1 2017, In : Japanese Journal of Cancer and Chemotherapy. 44, 5, p. 362-366 5 p.

Research output: Contribution to journalArticle

MicroRNAs
Neoplasms
Tumor Microenvironment
Biomarkers
Exosomes
42 Citations (Scopus)

MicroRNAs as biomarkers in colorectal cancer

Masuda, T., Hayashi, N., Kuroda, Y., Ito, S., Eguchi, H. & Mimori, K., Sep 13 2017, In : Cancers. 9, 9, 124.

Research output: Contribution to journalReview article

MicroRNAs
Colorectal Neoplasms
Biomarkers
Neoplasms
Organ Specificity
14 Citations (Scopus)

MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation

Otsubo, K., Goto, H., Nishio, M., Kawamura, K., Yanagi, S., Nishie, W., Sasaki, T., Maehama, T., Nishina, H., Mimori, K., Nakano, T., Shimizu, H., Mak, T. W., Nakao, K., Nakanishi, Y. & Suzuki, A., Jul 20 2017, In : Oncogene. 36, 29, p. 4201-4211 11 p.

Research output: Contribution to journalArticle

Cell Adhesion
Cell Differentiation
Doxycycline
Alveolar Epithelial Cells
Neoplasms
6 Citations (Scopus)

Overexpression of CXCR7 Is a novel prognostic indicator in gastric cancer

Nambara, S., Iguchi, T., Oki, E., Tan, P., Maehara, Y. & Mimori, K., Jul 1 2017, In : Digestive surgery. 34, 4, p. 312-318 7 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Singapore
Messenger RNA
CCR Receptors
Genes
7 Citations (Scopus)

Overexpression of heat-shock factor 1 is associated with a poor prognosis in esophageal squamous cell carcinoma

Tsukao, Y., Yamasaki, M., Miyazaki, Y., Makino, T., Takahashi, T., Kurokawa, Y., Miyata, H., Nakajima, K., Takiguchi, S., Mimori, K., Mori, M. & Doki, Y., Mar 2017, In : Oncology Letters. 13, 3, p. 1819-1825 7 p.

Research output: Contribution to journalArticle

Shock
Hot Temperature
Confidence Intervals
Esophageal Squamous Cell Carcinoma
HSP27 Heat-Shock Proteins
9 Citations (Scopus)

Phosphoserine phosphatase is a novel prognostic biomarker on chromosome 7 in colorectal cancer

Sato, K., Masuda, T., Hu, Q., Tobo, T., Kidogami, S., Ogawa, Y., Saito, T., Nambara, S., Komatsu, H., Hirata, H., Sakimura, S., Uchi, R., Hayashi, N., Iguchi, T., Eguchi, H., Ito, S., Nakagawa, T. & Mimori, K., May 2017, In : Anticancer research. 37, 5, p. 2365-2371 7 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 7
Colorectal Neoplasms
Biomarkers
Atlases
Genes
4 Citations (Scopus)

phyC: Clustering cancer evolutionary trees

Matsui, Y., Niida, A., Uchi, R., Mimori, K., Miyano, S. & Shimamura, T., May 2017, In : PLoS Computational Biology. 13, 5, e1005509.

Research output: Contribution to journalArticle

Evolutionary Tree
Cluster Analysis
Tumors
cancer
Cancer
4 Citations (Scopus)

Significance of CD47 expression in gastric cancer

Sudo, T., Takahashi, Y., Sawada, G., Uchi, R., Mimori, K. & Akagi, Y., Jan 1 2017, In : Oncology Letters. 14, 1, p. 801-809 9 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Bone Marrow
Neoplasms
Lymph Nodes
Lymphocytes
23 Citations (Scopus)

The Expression of CCAT2, a Novel Long Noncoding RNA Transcript, and rs6983267 Single-Nucleotide Polymorphism Genotypes in Colorectal Cancers

Kasagi, Y., Oki, E., Ando, K., Ito, S., Iguchi, T., Sugiyama, M., Nakashima, Y., Ohgaki, K., Saeki, H., Mimori, K. & Maehara, Y., Jan 1 2017, In : Oncology (Switzerland). 92, 1, p. 48-54 7 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Colonic Neoplasms
Single Nucleotide Polymorphism
Colorectal Neoplasms
Genotype
2 Citations (Scopus)

The loss of CASP4 expression is associated with poor prognosis in esophageal squamous cell carcinoma

Shibamoto, M., Hirata, H., Eguchi, H., Sawada, G., Sakai, N., Kajiyama, Y. & Mimori, K., Mar 2017, In : Oncology Letters. 13, 3, p. 1761-1766 6 p.

Research output: Contribution to journalArticle

Caspases
Endoplasmic Reticulum Stress
Comparative Genomic Hybridization
Gene Dosage
Esophageal Squamous Cell Carcinoma
1 Citation (Scopus)

Up-regulation of SLC9A9 promotes cancer progression and is involved in poor prognosis in colorectal cancer

Ueda, M., Iguchi, T., Masuda, T., Komatsu, H., Nambara, S., Sakimura, S., Hirata, H., Uchi, R., Eguchi, H., Ito, S., Sugimachi, K., Mizushima, T., Doki, Y., Mori, M. & Mimori, K., May 2017, In : Anticancer research. 37, 5, p. 2255-2263 9 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Up-Regulation
Neoplasms
Glioblastoma
Growth
2016
1 Citation (Scopus)

8q24 Polymorphisms and Diabetes Mellitus Regulate Apolipoprotein A-IV in Colorectal Carcinogenesis

Sugimachi, K., Yamaguchi, R., Eguchi, H., Ueda, M., Niida, A., Sakimura, S., Hirata, H., Uchi, R., Shinden, Y., Iguchi, T., Morita, K., Yamamoto, K., Miyano, S., Mori, M., Maehara, Y. & Mimori, K., Aug 1 2016, In : Annals of Surgical Oncology. 23, p. 546-551 6 p.

Research output: Contribution to journalArticle

Diabetes Mellitus
Carcinogenesis
Single Nucleotide Polymorphism
Colorectal Neoplasms
Lipid Metabolism
6 Citations (Scopus)

Aberrant Methylation of FOXE1 Contributes to a Poor Prognosis for Patients with Colorectal Cancer

Sugimachi, K., Matsumura, T., Shimamura, T., Hirata, H., Uchi, R., Ueda, M., Sakimura, S., Iguchi, T., Eguchi, H., Masuda, T., Morita, K., Takenaka, K., Maehara, Y., Mori, M. & Mimori, K., Nov 1 2016, In : Annals of Surgical Oncology. 23, 12, p. 3948-3955 8 p.

Research output: Contribution to journalArticle

Methylation
Colorectal Neoplasms
DNA Methylation
Neoplasm Metastasis
Genes
44 Citations (Scopus)

Clinical and biological significance of circulating tumor cells in cancer

Masuda, T., Hayashi, N., Iguchi, T., Ito, S., Eguchi, H. & Mimori, K., Mar 1 2016, In : Molecular Oncology. 10, 3, p. 408-417 10 p.

Research output: Contribution to journalReview article

Circulating Neoplastic Cells
Neoplasms
Neoplasm Metastasis
Bone Marrow
Mesenchymal Stromal Cells
1 Citation (Scopus)

Clinical and biological significance of transcription termination factor, RNA polymerase i in human liver hepatocellular carcinoma

Komatsu, H., Iguchi, T., Ueda, M., Nambara, S., Saito, T., Hirata, H., Sakimura, S., Takano, Y., Uchi, R., Shinden, Y., Eguchi, H., Masuda, T., Sugimachi, K., Doki, Y., Mori, M. & Mimori, K., Apr 2016, In : Oncology reports. 35, 4, p. 2073-2080 8 p.

Research output: Contribution to journalArticle

DNA-Directed RNA Polymerases
Hepatocellular Carcinoma
Transcription Factors
Liver
Pol1 Transcription Initiation Complex Proteins
38 Citations (Scopus)

Decreased expression of fructose-1,6-bisphosphatase associates with glucose metabolism and tumor progression in hepatocellular carcinoma

Hirata, H., Sugimachi, K., Komatsu, H., Ueda, M., Masuda, T., Uchi, R., Sakimura, S., Nambara, S., Saito, T., Shinden, Y., Iguchi, T., Eguchi, H., Ito, S., Terashima, K., Sakamoto, K., Hirakawa, M., Honda, H. & Mimori, K., Jun 1 2016, In : Cancer Research. 76, 11, p. 3265-3276 12 p.

Research output: Contribution to journalArticle

Fructose-Bisphosphatase
Hepatocellular Carcinoma
Glucose
Neoplasms
Gluconeogenesis
10 Citations (Scopus)

Downregulation of SIRT4 expression is associated with poor prognosis in esophageal squamous cell carcinoma

Nakahara, Y., Yamasaki, M., Sawada, G., Miyazaki, Y., Makino, T., Takahashi, T., Kurokawa, Y., Nakajima, K., Takiguchi, S., Mimori, K., Mori, M. & Doki, Y., Jun 14 2016, In : Oncology (Switzerland). 90, 6, p. 347-355 9 p.

Research output: Contribution to journalArticle

Down-Regulation
Glutamate Dehydrogenase
Survival
Glutamine
Disease-Free Survival
66 Citations (Scopus)

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice

Nishio, M., Sugimachi, K., Goto, H., Wang, J., Morikawa, T., Miyachi, Y., Takano, Y., Hikasa, H., Itoh, T., Suzuki, S. O., Kurihara, H., Aishima, S., Leask, A., Sasaki, T., Nakano, T., Nishina, H., Nishikawa, Y., Sekido, Y., Nakao, K., Shin-Ya, K. & 2 others, Mimori, K. & Suzuki, A., Jan 5 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 1, p. E71-E80

Research output: Contribution to journalArticle

Cholangiocarcinoma
Transforming Growth Factor beta
Liver Neoplasms
Liver
Phosphotransferases
20 Citations (Scopus)

Expression of PD-L1 and HLA Class I in Esophageal Squamous Cell Carcinoma: Prognostic Factors for Patient Outcome

Ito, S., Okano, S., Morita, M., Saeki, H., Tsutsumi, S., Tsukihara, H., Nakashima, Y., Ando, K., Imamura, Y., Ohgaki, K., Oki, E., Kitao, H., Mimori, K. & Maehara, Y., Aug 1 2016, In : Annals of Surgical Oncology. 23, p. 508-515 8 p.

Research output: Contribution to journalArticle

CD274 Antigen
HLA Antigens
Survival
Recurrence
Confidence Intervals
94 Citations (Scopus)

Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population

Sawada, G., Niida, A., Uchi, R., Hirata, H., Shimamura, T., Suzuki, Y., Shiraishi, Y., Chiba, K., Imoto, S., Takahashi, Y., Iwaya, T., Sudo, T., Hayashi, T., Takai, H., Kawasaki, Y., Matsukawa, T., Eguchi, H., Sugimachi, K., Tanaka, F., Suzuki, H. & 24 others, Yamamoto, K., Ishii, H., Shimizu, M., Yamazaki, H., Yamazaki, M., Tachimori, Y., Kajiyama, Y., Natsugoe, S., Fujita, H., Mafune, K., Tanaka, Y., Kelsell, D. P., Scott, C. A., Tsuji, S., Yachida, S., Shibata, T., Sugano, S., Doki, Y., Akiyama, T., Aburatani, H., Ogawa, S., Miyano, S., Mori, M. & Mimori, K., May 1 2016, In : Gastroenterology. 150, 5, p. 1171-1182 12 p.

Research output: Contribution to journalArticle

Mutation
Population
Japan
Smoking
Esophageal Neoplasms
9 Citations (Scopus)

HMGA1 silencing reduces stemness and temozolomide resistance in glioblastoma stem cells

Colamaio, M., Tosti, N., Puca, F., Mari, A., Gattordo, R., Kuzay, Y., Federico, A., Pepe, A., Sarnataro, D., Ragozzino, E., Raia, M., Hirata, H., Gemei, M., Mimori, K., del Vecchio, L., Battista, S. & Fusco, A., Oct 2 2016, In : Expert Opinion on Therapeutic Targets. 20, 10, p. 1169-1179 11 p.

Research output: Contribution to journalArticle

temozolomide
Neoplastic Stem Cells
Glioblastoma
Stem cells
Tumors
5 Citations (Scopus)

HOXB7 expression is a novel biomarker for long-term prognosis after resection of hepatocellular carcinoma

Komatsu, H., Iguchi, T., Masuda, T., Ueda, M., Kidogami, S., Ogawa, Y., Nambara, S., Sato, K., Hu, Q., Saito, T., Hirata, H., Sakimura, S., Uchi, R., Hayashi, N., Ito, S., Eguchi, H., Sugimachi, K., Doki, Y., Mori, M. & Mimori, K., Jun 2016, In : Anticancer research. 36, 6, p. 2767-2773 7 p.

Research output: Contribution to journalArticle

Homeobox Genes
Hepatocellular Carcinoma
Biomarkers
Homeodomain Proteins
Liver