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2019
1 Citation (Scopus)

A novel model for treatment of hypertrophic pachymeningitis

Cui, Y., Masaki, K., Zhang, X., Yamasaki, R., Fujii, T., Ogata, H., Hayashida, S., Yamaguchi, H., Hyodo, F., Eto, H., Koyama, S., Iinuma, K., Yonekawa, T., Matsushita, T., Yoshida, M., Yamada, K., Kawano, M., Malissen, M., Malissen, B. & Kira, J., Mar 2019, In : Annals of Clinical and Translational Neurology. 6, 3, p. 431-444 14 p.

Research output: Contribution to journalArticle

Open Access
Transforming Growth Factors
Meningitis
irbesartan
Immunoglobulin G
B-Lymphocytes
1 Citation (Scopus)

Anti-neurofascin autoantibody and demyelination

Kira, J. I., Yamasaki, R. & Ogata, H., Nov 2019, In : Neurochemistry International. 130, 104360.

Research output: Contribution to journalReview article

Demyelinating Diseases
Autoantibodies
Immunoglobulin G
Nodal Protein
Contactin 1

Anti-plexin D1 antibodies are a novel biomarker for immune-mediated neuropathic pain

Fujii, T., Yamasaki, R. & Kira, J. I., Feb 1 2019, In : Clinical and Experimental Neuroimmunology. 10, 1, p. 7-8 2 p.

Research output: Contribution to journalComment/debate

Neuralgia
Biomarkers
Antibodies
plexin
1 Citation (Scopus)

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

International Multiple Sclerosis Genetics Consortium, Dec 1 2019, In : Nature communications. 10, 1, 2236.

Research output: Contribution to journalArticle

Open Access
Systems Biology
Regulator Genes
biology
genes
genome
Open Access
document markup languages
HTML
Systems Biology
Regulator Genes
biology

A visual task management application for acute ischemic stroke care

Matsumoto, S., Koyama, H., Nakahara, I., Ishii, A., Hatano, T., Ohta, T., Tanaka, K., Ando, M., Chihara, H., Takita, W., Tokunaga, K., Hashikawa, T., Funakoshi, Y., Kamata, T., Higashi, E., Watanabe, S., Kondo, D., Tsujimoto, A., Furuta, K., Ishihara, T. & 8 others, Hashimoto, T., Koge, J., Sonoda, K., Torii, T., Nakagaki, H., Yamasaki, R., Nagata, I. & Kira, J. I., Jan 1 2019, In : Frontiers in Neurology. 10, OCT, 1118.

Research output: Contribution to journalArticle

Open Access
Stroke
Communication
Blood Cell Count
Workflow
Information Dissemination

Brainstem posterior reversible encephalopathy syndrome in a case with Guillain–Barré syndrome

Yokoyama, J., Yamaguchi, H., Koge, J., Matsushita, T., Isobe, N., Yamasaki, R. & Kira, J. I., Nov 1 2019, In : Clinical and Experimental Neuroimmunology. 10, 4, p. 267-271 5 p.

Research output: Contribution to journalArticle

Posterior Leukoencephalopathy Syndrome
Brain Stem
Consciousness
Passive Immunization
Intravenous Immunoglobulins

Case of central nervous system inflammatory disease in late pregnancy

Isobe, N., Baba, T., Nakamura, Y., Shinoda, K., Watanabe, M., Matsushita, T. & Kira, J. I., Mar 2019, In : Clinical and Experimental Neuroimmunology. 10, S1, p. 54-58 5 p.

Research output: Contribution to journalArticle

Open Access
Central Nervous System Diseases
Pregnancy
Dysarthria
Myoclonus
Hypesthesia
1 Citation (Scopus)

Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis

Harada, Y., Zhang, J., Imari, K., Yamasaki, R., Ni, J., Wu, Z., Yamamoto, K., Kira, J. I., Nakanishi, H. & Hayashi, Y., Sep 1 2019, In : Pain. 160, 9, p. 2050-2062 13 p.

Research output: Contribution to journalArticle

Cathepsin E
Autoimmune Experimental Encephalomyelitis
Neuralgia
Neutrophils
Hyperalgesia

Cerebrospinal fluid cytokine/chemokine/growth factor profiles in idiopathic hypertrophic pachymeningitis

Zhang, X., Fujii, T., Ogata, H., Yamasaki, R., Masaki, K., Cui, Y., Matsushita, T., Isobe, N. & Kira, J. I., May 15 2019, In : Journal of Neuroimmunology. 330, p. 38-43 6 p.

Research output: Contribution to journalArticle

Nervous System Diseases
Meningitis
Chemokines
Cerebrospinal Fluid
Intercellular Signaling Peptides and Proteins

Cognition with magnetic resonance imaging findings and social activities in patients with multiple sclerosis in a Japanese cohort

Niino, M., Fukazawa, T., Kira, J. I., Okuno, T., Mori, M., Sanjo, N., Ohashi, T., Fukaura, H., Fujimori, J., Shimizu, Y., Mifune, N., Miyazaki, Y., Takahashi, E., Kikuchi, S., Langdon, D., Benedict, R. H. B. & Matsui, M., Feb 1 2019, In : Clinical and Experimental Neuroimmunology. 10, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

Cognition
Multiple Sclerosis
Magnetic Resonance Imaging
Verbal Learning
Analysis of Variance
Limbic Encephalitis
Voltage-Gated Potassium Channels
Creutzfeldt-Jakob Syndrome
Antibodies

Differences between predictive factors for early neurological deterioration due to hemorrhagic and ischemic insults following intravenous recombinant tissue plasminogen activator

Tanaka, K., Matsumoto, S., Furuta, K., Yamada, T., Nagano, S., Takase, K. I., Hatano, T., Yamasaki, R. & Kira, J. I., Jan 1 2019, (Accepted/In press) In : Journal of Thrombosis and Thrombolysis.

Research output: Contribution to journalArticle

Open Access
Tissue Plasminogen Activator
Stroke
Odds Ratio
Confidence Intervals
Tomography
Chronic Progressive Multiple Sclerosis
Neuroimaging
Cross-Sectional Studies
Oligoclonal Bands
Colony-Stimulating Factor Receptors
2 Citations (Scopus)
Gyrus Cinguli
Alzheimer Disease
Temporal Lobe
Brain
Frontal Lobe
2 Citations (Scopus)

Grand Total EEG score can differentiate Parkinson's disease from Parkinson-related disorders

Barcelon, E. A., Mukaino, T., Yokoyama, J., Uehara, T., Ogata, K., Kira, J. I. & Tobimatsu, S., Jan 1 2019, In : Frontiers in Neurology. 10, APR, 398.

Research output: Contribution to journalArticle

Open Access
Parkinson Disease
Electroencephalography
Parkinsonian Disorders
Multiple System Atrophy
Paralysis
2 Citations (Scopus)

Helicobacter pylori infection and demyelinating disease of the central nervous system

Kira, J. I. & Isobe, N., Apr 15 2019, In : Journal of Neuroimmunology. 329, p. 14-19 6 p.

Research output: Contribution to journalReview article

Helicobacter Infections
Demyelinating Diseases
Helicobacter pylori
Central Nervous System
Neuromyelitis Optica

Higher postictal parasympathetic activity following greater ictal heart rate increase in right- than left-sided seizures

Shimmura, M., Uehara, T., Ogata, K., Shigeto, H., Maeda, T., Sakata, A., Yamasaki, R. & Kira, J. I., Aug 2019, In : Epilepsy and Behavior. 97, p. 161-168 8 p.

Research output: Contribution to journalArticle

Seizures
Heart Rate
Stroke
ROC Curve
Partial Epilepsy
1 Citation (Scopus)

Intractable axonal neuropathy with multifocal peripheral nerve swelling in neuromyelitis optica spectrum disorders: A case report

Mizuno, Y., Shinoda, K., Watanabe, M., Ogata, H., Isobe, N., Matsushita, T., Yamasaki, R., Tanaka, K., Koike, H., Katsuno, M. & Kira, J. I., Oct 2019, In : Multiple Sclerosis and Related Disorders. 35, p. 16-18 3 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Peripheral Nerves
Upper Extremity
Aquaporin 4
Magnetic Resonance Spectroscopy

Intrathecal cytokine profile in neuropathy with anti-neurofascin 155 antibody

Ogata, H., Zhang, X., Yamasaki, R., Fujii, T., Machida, A., Morimoto, N., Kaida, K., Masuda, T., Ando, Y., Kuwahara, M., Kusunoki, S., Nakamura, Y., Matsushita, T., Isobe, N. & Kira, J. I., Nov 1 2019, In : Annals of Clinical and Translational Neurology. 6, 11, p. 2304-2316 13 p.

Research output: Contribution to journalArticle

Open Access
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Cytokines
Antibodies
Interleukin-13
Interleukin-8

Long-term use of interferon-β in multiple sclerosis increases Vδ1-Vδ2-Vγ9- γδ T cells that are associated with a better outcome

Maimaitijiang, G., Watanabe, M., Shinoda, K., Isobe, N., Nakamura, Y., Masaki, K., Matsushita, T., Yoshikai, Y. & Kira, J. I., Sep 13 2019, In : Journal of neuroinflammation. 16, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Interferons
Multiple Sclerosis
T-Lymphocytes
B-Lymphocytes
T-Lymphocyte Subsets

Modified diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomography Score including deep white matter lesions predicts symptomatic intracerebral hemorrhage following intravenous thrombolysis

Tanaka, K., Matsumoto, S., Furuta, K., Yamada, T., Nagano, S., Takase, K. I., Hatano, T., Yamasaki, R. & Kira, J. I., Jan 1 2019, (Accepted/In press) In : Journal of Thrombosis and Thrombolysis.

Research output: Contribution to journalArticle

Open Access
Alberta
Cerebral Hemorrhage
Stroke
Tomography
Tissue Plasminogen Activator
3 Citations (Scopus)
Myelin-Oligodendrocyte Glycoprotein
Central Nervous System Vasculitis
Immunotherapy
Antibodies
Cerebrum
Mitochondrial DNA
Mitochondria
Pharmaceutical Preparations

Multiple Sclerosis

Yamasaki, R. & Kira, J. I., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer, p. 217-247 31 p. (Advances in Experimental Medicine and Biology; vol. 1190).

Research output: Chapter in Book/Report/Conference proceedingChapter

Multiple Sclerosis
T-cells
Neurology
Demyelinating Diseases
T-Lymphocytes

Neuromagnetic correlates of hemispheric specialization for face and word recognition

Inamizu, S., Yamada, E., Ogata, K., Uehara, T., Kira, J. I. & Tobimatsu, S., Jan 1 2019, (Accepted/In press) In : Neuroscience Research.

Research output: Contribution to journalArticle

Open Access
Cerebral Dominance
Visual Fields
Word Processing
Magnetic Fields
Young Adult

Novel Neuropathic Pain Mechanisms Associated With Allergic Inflammation

Fujii, T., Yamasaki, R. & Kira, J. I., Dec 17 2019, In : Frontiers in Neurology. 10, 1337.

Research output: Contribution to journalReview article

Open Access
Neuralgia
Inflammation
Spinal Ganglia
Endothelin B Receptors
Hyperalgesia

Recurrent rhombencephalomyelitis associated with allergen immunotherapy by mite antigen sublingual tablets

Kawajiri, M., Koge, J., Hashimoto, T., Yamada, T., Isobe, N. & Kira, J. I., Jun 2019, In : eNeurologicalSci. 15, 100190.

Research output: Contribution to journalLetter

Open Access
Myelitis
Immunologic Desensitization
Mites
Immunotherapy
Allergens
1 Citation (Scopus)

Serum GFAP and neurofilament light as biomarkers of disease activity and disability in NMOSD

Watanabe, M., Nakamura, Y., Michalak, Z., Isobe, N., Barro, C., Leppert, D., Matsushita, T., Hayashi, F., Yamasaki, R., Kuhle, J. & Kira, J. I., Sep 24 2019, In : Neurology. 93, 13, p. e1299-e1311

Research output: Contribution to journalArticle

Neuromyelitis Optica
Intermediate Filaments
Glial Fibrillary Acidic Protein
Blood Proteins
Biomarkers
3 Citations (Scopus)

Simultaneous MR neurography and apparent T2 mapping in brachial plexus: Evaluation of patients with chronic inflammatory demyelinating polyradiculoneuropathy

Hiwatashi, A., Togao, O., Yamashita, K., Kikuchi, K., Momosaka, D., Nakatake, H., Yamasaki, R., Ogata, H., Yoneyama, M., Kira, J. I. & Honda, H., Jan 2019, In : Magnetic Resonance Imaging. 55, p. 112-117 6 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Brachial Plexus
Relaxation time
Healthy Volunteers
Ganglia
2 Citations (Scopus)

Temporal Trends in Clinical Characteristics and Door-to-Needle Time in Patients Receiving Intravenous Tissue Plasminogen Activator: A Retrospective Study of 4 Hospitals in Japan

Tanaka, K., Matsumoto, S., Yamada, T., Nagano, S., Takase, K. I., Hatano, T., Yamasaki, R. & Kira, J. I., Nov 2019, In : Journal of Stroke and Cerebrovascular Diseases. 28, 11, 104305.

Research output: Contribution to journalArticle

Tissue Plasminogen Activator
Needles
Japan
Retrospective Studies
Stroke
2 Citations (Scopus)

Toxic myopathy with multiple deletions in mitochondrial DNA associated with long-term use of oral anti-viral drugs for hepatitis B: A case study

Fujii, T., Takase, K. I., Honda, H., Kawamura, N., Yamasaki, R., Urata, M., Uchiumi, T., Iwaki, T. & Kira, J. I., Apr 2019, In : Neuropathology. 39, 2, p. 162-167 6 p.

Research output: Contribution to journalArticle

Poisons
Muscular Diseases
Hepatitis B
Mitochondrial DNA
Nucleosides
2016
1 Citation (Scopus)

A case of cerebrotendinous xanthomatosis mimicking the clinical phenotype of mitochondrial disease with a novel frame-shift mutation (c. 43-44 delGG) in CYP27A1 gene exon 1

Koge, J., Hayashi, S., Yamaguchi, H., Tateishi, T., Murai, H. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 10, p. 667-671 5 p.

Research output: Contribution to journalArticle

Cerebrotendinous Xanthomatosis
Mitochondrial Diseases
Frameshift Mutation
MERRF Syndrome
Cholestanol
1 Citation (Scopus)

A case of paroxysmal sympathetic storm after acute disseminated encephalomyelitis and hypoxic encephalopathy responding to clonidine hydrochloride

Shimmura, M., Kawamura, N., Tateishi, T., Shigeto, H., Murai, H. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 2, p. 108-111 4 p.

Research output: Contribution to journalArticle

Acute Disseminated Encephalomyelitis
Brain Hypoxia
Clonidine
Decerebrate State
Tachypnea

A case of primary central nervous system vasculitis diagnosed by second brain biopsy and treated successfully

Mizuno, Y., Shigeto, H., Yamada, T., Maeda, N., Suzuki, S. O. & Kira, J. I., Jan 1 2016, In : Clinical Neurology. 56, 3, p. 186-190 5 p.

Research output: Contribution to journalArticle

Central Nervous System Vasculitis
Biopsy
Brain
Frontal Lobe
Diplopia
3 Citations (Scopus)
MELAS Syndrome
Rhabdomyolysis
Status Epilepticus
Stroke
Occipital Lobe
10 Citations (Scopus)

Allergic inflammation leads to neuropathic pain via glial cell activation

Yamasaki, R., Fujii, T., Wang, B., Masaki, K., Kido, M. A., Yoshida, M., Matsushita, T. & Kira, J. I., Nov 23 2016, In : Journal of Neuroscience. 36, 47, p. 11929-11945 17 p.

Research output: Contribution to journalArticle

Endothelin B Receptors
Neuralgia
Neuroglia
Microglia
Inflammation
31 Citations (Scopus)

A nationwide survey of combined central and peripheral demyelination in Japan

Ogata, H., Matsuse, D., Yamasaki, R., Kawamura, N., Matsushita, T., Yonekawa, T., Hirotani, M., Murai, H. & Kira, J. I., Jan 1 2016, In : Journal of Neurology, Neurosurgery and Psychiatry. 87, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

Demyelinating Diseases
Japan
Oligoclonal Bands
Visual Evoked Potentials
Peripheral Nervous System
19 Citations (Scopus)

A nationwide survey of pediatric acquired demyelinating syndromes in Japan

Yamaguchi, Y., Torisu, H., Kira, R., Ishizaki, Y., Sakai, Y., Sanefuji, M., Ichiyama, T., Oka, A., Kishi, T., Kimura, S., Kubota, M., Takanashi, J., Takahashi, Y., Tamai, H., Natsume, J., Hamano, S., Hirabayashi, S., Maegaki, Y., Mizuguchi, M., Minagawa, K. & 4 others, Yoshikawa, H., Kira, J., Kusunoki, S. & Hara, T., Nov 8 2016, In : Neurology. 87, 19, p. 2006-2015 10 p.

Research output: Contribution to journalArticle

Japan
Acute Disseminated Encephalomyelitis
Neuromyelitis Optica
Pediatrics
Multiple Sclerosis
3 Citations (Scopus)

Antibodies to myelin oligodendrocyte glycoprotein are uncommon in Japanese opticospinal multiple sclerosis

Ramanathan, S., Sato, S., Matsushita, T., Masaki, K., Yamasaki, R., Dale, R. C., Kira, J. I. & Brilot, F., Jan 1 2016, In : Multiple Sclerosis. 22, 1, p. 127-128 2 p.

Research output: Contribution to journalLetter

Myelin-Oligodendrocyte Glycoprotein
Neuromyelitis Optica
Antibodies
Opticospinal Multiple Sclerosis

Antibodies to myelin oligodendrocyte glycoprotein are uncommon in Japanese opticospinal multiple sclerosis

Ramanathan, S., Sato, S., Matsushita, T., Masaki, K., Yamasaki, R., Dale, R. C., Kira, J. I. & Brilot, F., Jan 1 2016, In : Multiple Sclerosis. 22, 1, p. 127-128 2 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Neuromyelitis Optica
Autoantibodies
Multiple Sclerosis
Young Adult
8 Citations (Scopus)

A Potential VEP Biomarker for Mild Cognitive Impairment: Evidence from Selective Visual Deficit of Higher-Level Dorsal Pathway

Yamasaki, T., Horie, S., Ohyagi, Y., Tanaka, E., Nakamura, N., Goto, Y., Kanba, S., Kira, J. I., Tobimatsu, S. & Mandal, P., Jan 1 2016, In : Journal of Alzheimer's Disease. 53, 2, p. 661-676 16 p.

Research output: Contribution to journalArticle

Visual Evoked Potentials
Biomarkers
Neuropsychological Tests
ROC Curve
Optic Flow
7 Citations (Scopus)

Chondroitin sulfate β-1,4-N-acetylgalactosaminyltransferase-1 (ChGn-1) polymorphism: Association with progression of multiple sclerosis

Saigoh, K., Yoshimura, S., Izumikawa, T., Miyata, S., Tabara, Y., Matsushita, T., Miki, T., Miyamoto, K., Hirano, M., Kitagawa, H., Kira, J. I. & Kusunoki, S., Jul 1 2016, In : Neuroscience Research. 108, p. 55-59 5 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Chondroitin Sulfate Proteoglycans
Single Nucleotide Polymorphism
Central Nervous System
Genes

Dermatomyositis complicated with asymmetric peripheral neuritis on exacerbation: A case report and literature review

Irie, T., Shigeto, H., Koge, J., Yamaguchi, H., Murai, H. & Kira, J. I., Nov 1 2016, In : Clinical and Experimental Neuroimmunology. 7, 4, p. 373-380 8 p.

Research output: Contribution to journalArticle

Neuritis
Dermatomyositis
Mononeuropathies
Peroneal Nerve
Muscle Weakness
15 Citations (Scopus)

Efficacy of intravenous methylprednisolone pulse therapy in patients with multiple sclerosis and neuromyelitis optica

Yamasaki, R., Matsushita, T., Fukazawa, T., Yokoyama, K., Fujihara, K., Ogino, M., Yokota, T., Miyamoto, K., Niino, M., Nomura, K., Tomioka, R., Tanaka, M., Kawachi, I., Ohashi, T., Kaida, K. I., Matsui, M., Nakatsuji, Y., Ochi, H., Fukaura, H., Kanda, T. & 5 others, Nagaishi, A., Togo, K., Mizusawa, H., Murai, H. & Kira, J. I., Sep 1 2016, In : Multiple Sclerosis. 22, 10, p. 1337-1348 12 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Methylprednisolone
Multiple Sclerosis
Therapeutics
Signs and Symptoms
45 Citations (Scopus)

Histopathologic Analysis of Retrieved Thrombi Associated with Successful Reperfusion after Acute Stroke Thrombectomy

Hashimoto, T., Hayakawa, M., Funatsu, N., Yamagami, H., Satow, T., Takahashi, J. C., Nagatsuka, K., Ishibashi-Ueda, H., Kira, J. I. & Toyoda, K., Dec 1 2016, In : Stroke. 47, 12, p. 3035-3037 3 p.

Research output: Contribution to journalArticle

Thrombectomy
Reperfusion
Thrombosis
Stroke
Erythrocytes
28 Citations (Scopus)

IgG4 anti-neurofascin155 antibodies in chronic inflammatory demyelinating polyradiculoneuropathy: Clinical significance and diagnostic utility of a conventional assay

Kadoya, M., Kaida, K., Koike, H., Takazaki, H., Ogata, H., Moriguchi, K., Shimizu, J., Nagata, E., Takizawa, S., Chiba, A., Yamasaki, R., Kira, J. I., Sobue, G. & Ikewaki, K., Dec 15 2016, In : Journal of Neuroimmunology. 301, p. 16-22 7 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Anti-Idiotypic Antibodies
Immunoglobulin G
Enzyme-Linked Immunosorbent Assay
Antibodies
1 Citation (Scopus)

Immune-mediated spastic paraparesis accompanied with high titres of voltage-gated potassium channel complex antibodies and myokymia/fasciculation

Saitoh, B. Y., Hayashi, S., Ogata, K., Uehara, T., Doi, H., Watanabe, O., Yamasaki, R., Murai, H. & Kira, J. I., May 15 2016, In : Journal of the Neurological Sciences. 364, p. 133-135 3 p.

Research output: Contribution to journalLetter

12 Citations (Scopus)

Latitude and HLA-DRB1*04:05 independently influence disease severity in Japanese multiple sclerosis: A cross-sectional study

Nakamura, Y., Matsushita, T., Sato, S., Niino, M., Fukazawa, T., Yoshimura, S., Hisahara, S., Isobe, N., Shimohama, S., Watanabe, M., Yoshida, K., Houzen, H., Miyazaki, Y., Yamasaki, R., Kikuchi, S. & Kira, J. I., Sep 6 2016, In : Journal of neuroinflammation. 13, 1, 239.

Research output: Contribution to journalArticle

HLA Antigens
Multiple Sclerosis
Cross-Sectional Studies
Cerebrospinal Fluid
Immunoglobulin G