Find Research Outputs

Search concepts
Selected filters
2018
1 Citation (Scopus)

A case of multiple system atrophy-parkinsonian type with stuttering- and palilalia-like dysfluencies and putaminal atrophy

Kikuchi, Y., Umezaki, T., Uehara, T., Yamaguchi, H., Yamashita, K., Hiwatashi, A., Sawatsubashi, M., Adachi, K., Yamaguchi, Y., Murakami, D., Kira, J. I. & Nakagawa, T., Sep 2018, In : Journal of Fluency Disorders. 57, p. 51-58 8 p.

Research output: Contribution to journalArticle

Multiple System Atrophy
Stuttering
Atrophy
deficit
Putamen
2 Citations (Scopus)

A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression

Nakamura, Y., Gaetano, L., Matsushita, T., Anna, A., Sprenger, T., Radue, E. W., Wuerfel, J., Bauer, L., Amann, M., Shinoda, K., Isobe, N., Yamasaki, R., Saida, T., Kappos, L. & Kira, J. I., Sep 5 2018, In : Journal of neuroinflammation. 15, 1, 255.

Research output: Contribution to journalArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Brain
Atrophy
Relapsing-Remitting Multiple Sclerosis
3 Citations (Scopus)

A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain

Fujii, T., Yamasaki, R., Iinuma, K., Tsuchimoto, D., Hayashi, Y., Saitoh, B. Y., Matsushita, T., Kido, M. A., Aishima, S., Nakanishi, H., Nakabeppu, Y. & Kira, J. I., Aug 2018, In : Annals of Neurology. 84, 2, p. 208-224 17 p.

Research output: Contribution to journalArticle

Neuralgia
Autoantibodies
Spinal Ganglia
Neurons
Unmyelinated Nerve Fibers
2 Citations (Scopus)

Association of decreased percentage of Vδ2+Vγ9+ γδ T cells with disease severity in multiple sclerosis

Maimaitijiang, G., Shinoda, K., Nakamura, Y., Masaki, K., Matsushita, T., Isobe, N., Yamasaki, R., Yoshikai, Y. & Kira, J. I., Apr 10 2018, In : Frontiers in Immunology. 9, APR, 748.

Research output: Contribution to journalArticle

Multiple Sclerosis
T-Lymphocytes
Interferons
T-Cell Receptor Genes
T-Lymphocyte Gene Rearrangement
4 Citations (Scopus)

Chronic inflammatory demyelinating polyneuropathy with concurrent membranous nephropathy: An anti-paranode and podocyte protein antibody study and literature survey

Hashimoto, Y., Ogata, H., Yamasaki, R., Sasaguri, T., Ko, S., Yamashita, K., Xu, Z., Matsushita, T., Tateishi, T., Akiyama, SI., Maruyama, S., Yamamoto, A. & Kira, J. I., Nov 27 2018, In : Frontiers in Neurology. 9, NOV, 00997.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Contactin 1
Podocytes
Membranous Glomerulonephritis
Antibodies
5 Citations (Scopus)
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Connexins
varespladib methyl
Astrocytes
Parkinson Disease
5 Citations (Scopus)
Connexins
Autoimmune Experimental Encephalomyelitis
Microglia
Connexin 43
Knockout Mice
Electrical Synapses
Anterior Horn Cells
Presynaptic Terminals
Amyotrophic Lateral Sclerosis
Down-Regulation
1 Citation (Scopus)

Duplication and deletion upstream of LMNB1 in autosomal dominant adult-onset leukodystrophy

Mezaki, N., Miura, T., Ogaki, K., Eriguchi, M., Mizuno, Y., Komatsu, K., Yamazaki, H., Suetsugi, N., Kawajiri, S., Yamasaki, R., Ishiguro, T., Konno, T., Nozaki, H., Kasuga, K., Okuma, Y., Kira, J. I., Hara, H., Onodera, O. & Ikeuchi, T., Dec 1 2018, In : Neurology: Genetics. 4, 6, e292.

Research output: Contribution to journalArticle

lamin B1
Leukoencephalopathies
Temporal Lobe
Reverse Transcription
Leukocytes
8 Citations (Scopus)

ELectron microscopic abnormality and therapeutic efficacy in chronic inflammatory demyelinating polyneuropathy with anti-neurofascin155 immunoglobulin G4 antibody

Kuwahara, M., Suzuki, H., Oka, N., Ogata, H., Yanagimoto, S., Sadakane, S., Fukumoto, Y., Yamana, M., Yuhara, Y., Yoshikawa, K., Morikawa, M., Kawai, S., Okazaki, M., Tsujimoto, T., Kira, J. I. & Kusunoki, S., Mar 2018, In : Muscle and Nerve. 57, 3, p. 498-502 5 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Immunoglobulins
Electrons
Antibodies
Sural Nerve

Elevated end-diastolic ratio of the common carotid artery due to cerebral arteriovenous malformation: Two case reports

Tanaka, K., Matsumoto, S., Yamada, T., Kondo, D., Chihara, H., Koga, M., Hatano, T., Miyagi, T., Yamasaki, R. & Kira, J. I., Aug 2018, In : Radiology Case Reports. 13, 4, p. 917-920 4 p.

Research output: Contribution to journalArticle

Intracranial Arteriovenous Malformations
Common Carotid Artery
Cerebral Veins
Nervous System Malformations
Headache Disorders

HLA genotype and cortical lesions: Response to the letter from Spencer et al.

Shinoda, K., Matsushita, T., Nakamura, Y., Masaki, K., Yamasaki, R. & Kira, J. I., May 1 2018, In : Multiple Sclerosis Journal. 24, 6, p. 819-820 2 p.

Research output: Contribution to journalLetter

Genotype

Hopkins syndrome following the first episode of bronchial asthma associated with enterovirus D68: A case report

Hayashi, F., Hayashi, S., Matsuse, D., Yamasaki, R., Yonekura, K. & Kira, J. I., May 23 2018, In : BMC neurology. 18, 1, 71.

Research output: Contribution to journalArticle

Enterovirus
Asthma
Respiratory Hypersensitivity
Lower Extremity
Adult Respiratory Distress Syndrome
2 Citations (Scopus)
Lumbosacral Plexus
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Spinal Ganglia
ROC Curve
Research Ethics Committees

Mitochondrial dysfunction and altered ribostasis in hippocampal neurons with cytoplasmic inclusions of multiple system atrophy

Maeda, N., Honda, H., Suzuki, S. O., Fujii, N., Kira, J. I. & Iwaki, T., Aug 2018, In : Neuropathology. 38, 4, p. 361-371 11 p.

Research output: Contribution to journalArticle

Multiple System Atrophy
Inclusion Bodies
Neurons
Hippocampus
Heterogeneous-Nuclear Ribonucleoproteins
8 Citations (Scopus)

Nationwide epidemiological study of neuromyelitis optica in Japan

Miyamoto, K., Fujihara, K., Kira, J. I., Kuriyama, N., Matsui, M., Tamakoshi, A. & Kusunoki, S., Jun 1 2018, In : Journal of neurology, neurosurgery, and psychiatry. 89, 6, p. 667-668 2 p.

Research output: Contribution to journalLetter

Neuromyelitis Optica
Epidemiologic Studies
Japan
7 Citations (Scopus)
Antirheumatic Agents
Autoimmune Experimental Encephalomyelitis
Macrophage Activation
Microglia
Demyelinating Diseases

Oral phase dysphagia in facial onset sensory and motor neuronopathy

Watanabe, M., Shiraishi, W., Yamasaki, R., Isobe, N., Sawatsubashi, M., Yasumatsu, R., Nakagawa, T. & Kira, J. I., Jun 2018, In : Brain and Behavior. 8, 6, e00999.

Research output: Contribution to journalArticle

Deglutition Disorders
Deglutition
Pharynx
Aspiration Pneumonia
Gastrostomy
7 Citations (Scopus)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Antibodies
Neural Conduction
Immunotherapy
Cerebrospinal Fluid Proteins
Neuromyelitis Optica
Gold
Dimethyl Fumarate
3 Citations (Scopus)

Restoration of a conduction block after the long-term treatment of CIDP with anti-neurofascin 155 antibodies: Follow-up of a case over 23 years

Koike, H., Nishi, R., Ikeda, S., Kawagashira, Y., Iijima, M., Atsuta, N., Nakamura, T., Hirayama, M., Ogata, H., Yamasaki, R., Kira, J. I., Katsuno, M. & Sobue, G., Jan 1 2018, In : Internal Medicine. 57, 14, p. 2061-2066 6 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Hypesthesia
Antibodies
Neural Conduction
Action Potentials

The contribution of glial inflammation in the pathogenesis of multiple sclerosis

Yamasaki, R. & Kira, J. I., Jan 1 2018, In : Neuro-Ophthalmology Japan. 35, 1, p. 4-10 7 p.

Research output: Contribution to journalArticle

Connexins
Neuroglia
Multiple Sclerosis
Inflammation
Recurrence

The neuropathological study of myelin oligodendrocyte glycoprotein in the temporal lobe of schizophrenia patients

Marui, T., Torii, Y., Iritani, S., Sekiguchi, H., Habuchi, C., Fujishiro, H., Oshima, K., Niizato, K., Hayashida, S., Masaki, K., Kira, J. & Ozaki, N., Aug 1 2018, In : Acta Neuropsychiatrica. 30, 4, p. 232-240 9 p.

Research output: Contribution to journalArticle

Myelin-Oligodendrocyte Glycoprotein
Temporal Lobe
Schizophrenia
Oligodendroglia
Brain
Vesicular Glutamate Transport Protein 2
STAT3 Transcription Factor
Transcriptional Activation
Glutamic Acid
Spinal Cord
2017
3 Citations (Scopus)

A case of anti-neurofascin 155 antibody-positive combined central and peripheral demyelination successfully treated with plasma exchange

Shimizu, M., Koda, T., Nakatsuji, Y., Ogata, H., Kira, J. I. & Mochizuki, H., Jan 1 2017, In : Clinical Neurology. 57, 1, p. 41-44 4 p.

Research output: Contribution to journalArticle

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Plasma Exchange
Demyelinating Diseases
Cerebrospinal Fluid
Anti-Idiotypic Antibodies
MELAS Syndrome
Rhabdomyolysis
Status Epilepticus
Stroke

A case of stiff-person syndrome due to secondary adrenal insufficiency

Mizuno, Y., Yamaguchi, H., Uehara, T., Yamashita, K., Yamasaki, R. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 6, p. 298-302 5 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Adrenal Insufficiency
Contracture
Hypopituitarism
Muscles

A case of superficial siderosis ameliorated after closure of dural deficit detected by MRI-CISS (constructive interference in steady state) imaging

Sakoda, A., Yamashita, K. I., Hayashida, M., Iwamoto, Y., Yamasaki, R. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 4, p. 180-183 4 p.

Research output: Contribution to journalArticle

Siderosis
Dizziness
Ataxia
Headache
Cerebrospinal Fluid
2 Citations (Scopus)

A novel mutation in FGD4 causes Charcot–Marie–Tooth disease type 4H with cranial nerve involvement

Kondo, D., Shinoda, K., Yamashita, K. I., Yamasaki, R., Hashiguchi, A., Takashima, H. & Kira, J. I., Oct 2017, In : Neuromuscular Disorders. 27, 10, p. 959-961 3 p.

Research output: Contribution to journalArticle

Cranial Nerves
Muscle Weakness
Scoliosis
Bilateral Hearing Loss
Facial Muscles
6 Citations (Scopus)

Apomorphine Therapy for Neuronal Insulin Resistance in a Mouse Model of Alzheimer's Disease

Nakamura, N., Ohyagi, Y., Imamura, T., Yanagihara, Y. T., Iinuma, K. M., Soejima, N., Murai, H., Yamasaki, R. & Kira, J. I., Jan 1 2017, In : Journal of Alzheimer's Disease. 58, 4, p. 1151-1161 11 p.

Research output: Contribution to journalArticle

Apomorphine
Insulin Resistance
Alzheimer Disease
Insulysin
Brain
3 Citations (Scopus)

Cerebral blood flow laterality derived from arterial spin labeling as a biomarker for assessing the disease severity of parkinson's disease

Yamashita, K., Hiwatashi, A., Togao, O., Kikuchi, K., Yamaguchi, H., Suzuki, Y., Kamei, R., Yamasaki, R., Kira, J. I. & Honda, H., Jun 2017, In : Journal of Magnetic Resonance Imaging. 45, 6, p. 1821-1826 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Parkinson Disease
Biomarkers
Caudate Nucleus
Globus Pallidus
2 Citations (Scopus)

Clinical characteristics of atrial fibrillation-related cardioembolic stroke in patients aged 80 years or older

Tanaka, K., Yamada, T., Torii, T., Matsumoto, S., Yoshimura, T., Takase, K. I., Wakata, Y., Nakashima, N., Kira, J. I. & Murai, H., May 2017, In : Geriatrics and Gerontology International. 17, 5, p. 708-713 6 p.

Research output: Contribution to journalArticle

stroke
Atrial Fibrillation
Stroke
mortality
Mortality
Amyotrophic Lateral Sclerosis
Neuroglia
Motor Neurons
Spinal Cord
Microglia
3 Citations (Scopus)
Amyotrophic Lateral Sclerosis
Neuroglia
Motor Neurons
Spinal Cord
Microglia
1 Citation (Scopus)
Vesicular Glutamate Transport Proteins
Amino Acid Transport System X-AG
Amyotrophic Lateral Sclerosis
Motor Neurons
Neuroglia
9 Citations (Scopus)

Early and extensive spinal white matter involvement in neuromyelitis optica

Hayashida, S., Masaki, K., Yonekawa, T., Suzuki, S. O., Hiwatashi, A., Matsushita, T., Watanabe, M., Yamasaki, R., Suenaga, T., Iwaki, T., Murai, H. & Kira, J. I., May 2017, In : Brain Pathology. 27, 3, p. 249-265 17 p.

Research output: Contribution to journalArticle

Neuromyelitis Optica
Aquaporin 4
Spinal Cord
Horns
Antibodies
9 Citations (Scopus)
Multiple System Atrophy
Chemokines
Cerebrospinal Fluid
Case-Control Studies
Cytokines
8 Citations (Scopus)

Efficacy, safety, and pharmacokinetics of natalizumab in Japanese multiple sclerosis patients: A double-blind, randomized controlled trial and open-label pharmacokinetic study

Saida, T., Kira, J. I., Kishida, S., Yamamura, T., Sudo, Y., Ogiwara, K., Tibung, J. T., Lucas, N. & Subramanyam, M., Jan 1 2017, In : Multiple Sclerosis and Related Disorders. 11, p. 25-31 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Randomized Controlled Trials
Pharmacokinetics
Safety
Relapsing-Remitting Multiple Sclerosis
10 Citations (Scopus)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Ganglia
Brachial Plexus
Signal-To-Noise Ratio
Research Ethics Committees

Extensive white matter pathology of longitudinally extensive myelitis in neuromyelitis optica

Hayashida, S., Masaki, K. & Kira, J. I., Feb 1 2017, In : Clinical and Experimental Neuroimmunology. 8, 1, p. 9-10 2 p.

Research output: Contribution to journalComment/debate

Neuromyelitis Optica
Myelitis
Pathology
White Matter
5 Citations (Scopus)

HLA-DRB1*04:05 allele is associated with intracortical lesions on three-dimensional double inversion recovery images in Japanese patients with multiple sclerosis

Shinoda, K., Matsushita, T., Nakamura, Y., Masaki, K., Yamasaki, R., Yamaguchi, H., Togao, O., Hiwatashi, A. & Kira, J-I., May 1 2017, In : Multiple Sclerosis. p. 1352458517707067

Research output: Contribution to journalArticle

Multiple Sclerosis
Alleles
HLA-DRB1 Chains
HLA-DRB1*04 antigen
Logistic Models
3 Citations (Scopus)

Improving treatment times for patients with in-hospital stroke using a standardized protocol

Koge, J., Matsumoto, S., Nakahara, I., Ishii, A., Hatano, T., Sadamasa, N., Kai, Y., Ando, M., Saka, M., Chihara, H., Takita, W., Tokunaga, K., Kamata, T., Nishi, H., Hashimoto, T., Tsujimoto, A., Kira, J. I. & Nagata, I., Oct 15 2017, In : Journal of the Neurological Sciences. 381, p. 68-73 6 p.

Research output: Contribution to journalArticle

Stroke
Neuroimaging
Therapeutics
Intracranial Hemorrhages
Clinical Protocols
7 Citations (Scopus)

Long-term efficacy and safety of fingolimod in Japanese patients with relapsing multiple sclerosis: 3-year results of the phase 2 extension study

Saida, T., Itoyama, Y., Kikuchi, S., Hao, Q., Kurosawa, T., Ueda, K., Auberson, L. Z., Tsumiyama, I., Nagato, K. & Kira, J. I., Jan 28 2017, In : BMC neurology. 17, 1, 17.

Research output: Contribution to journalArticle

Multiple Sclerosis
Safety
Placebos
Fingolimod Hydrochloride
Recurrence
10 Citations (Scopus)
Lumbosacral Plexus
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Polyneuropathies
Ganglia
ROC Curve
Common Carotid Artery
Arteries
Middle Cerebral Artery
Internal Carotid Artery
Ultrasonography
1 Citation (Scopus)

Natalizumab for Achieving Relapse-Free, T1 Gadolinium-Enhancing-Lesion-Free, and T2 Lesion-Free Status in Japanese Multiple Sclerosis Patients: A Phase 2 Trial Subanalysis

Saida, T., Kira, J. I., Kishida, S., Yamamura, T., Ohtsuka, N., Dong, Q. & Tibung, J. T., Jun 1 2017, In : Neurology and Therapy. 6, 1, p. 153-159 7 p.

Research output: Contribution to journalArticle

Gadolinium
Multiple Sclerosis
Recurrence
Relapsing-Remitting Multiple Sclerosis
Placebos
48 Citations (Scopus)

Paranodal dissection in chronic inflammatory demyelinating polyneuropathy with anti-neurofascin-155 and anti-contactin-1 antibodies

Koike, H., Kadoya, M., Kaida, K. I., Ikeda, S., Kawagashira, Y., Iijima, M., Kato, D., Ogata, H., Yamasaki, R., Matsukawa, N., Kira, J. I., Katsuno, M. & Sobue, G., Jun 1 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 6, p. 465-473 9 p.

Research output: Contribution to journalArticle

Contactin 1
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Dissection
Antibodies
Demyelinating Diseases
1 Citation (Scopus)

q-space Myelin Map imaging: A new imaging technique for treatment evaluation in multiple sclerosis

Kira, J. I., Feb 15 2017, In : Journal of the Neurological Sciences. 373, p. 358-359 2 p.

Research output: Contribution to journalComment/debate

Questionnaire survey on the process of specialty training in neurology in Japan

Sonoo, M., Nishiyama, K., Ando, T., Shindo, K., Kanda, T., Aoki, M., Kamei, S., Kikuchi, S., Kusunoki, S., Suzuki, N., Sobue, G., Nakashima, K., Hara, H., Hirata, K., Mizusawa, H., Murai, H., Murata, M., Mochizuki, H., Takahashi, R. & Kira, J. I., Jan 1 2017, In : Clinical Neurology. 57, 7, p. 402-410 9 p.

Research output: Contribution to journalReview article

Neurology
Japan
Internship and Residency
Urban Hospitals
Documentation
1 Citation (Scopus)

Re-emergence of a tumefactive demyelinating lesion after initiation of fingolimod therapy

Hashimoto, Y., Shinoda, K., Tanaka, E., Uehara, T., Matsushita, T., Yamasaki, R. & Kira, J. I., Aug 15 2017, In : Journal of the Neurological Sciences. 379, p. 167-168 2 p.

Research output: Contribution to journalLetter

Multiple Sclerosis
Therapeutics
Fingolimod Hydrochloride