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• 2016

  Antitumor Molecular Mechanism of Trifluridine and Tipiracil Hydrochloride (TAS-102: TFTD)

  Kitao, H., Matsuoka, K., Iimori, M., Tokunaga, E., Saeki, H., Oki, E., Miyamoto, Y., Baba, H. & Maehara, Y., Jan 1 2016, In: Gan to kagaku ryoho. Cancer & chemotherapy. 43, 1, p. 8-14 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • trifluridine tipiracil
  • Colorectal Neoplasms
  • Trifluridine
  • Salvage Therapy
  • Drug Therapy

• APOBEC3B is an enzymatic source of molecular alterations in esophageal squamous cell carcinoma

  Kosumi, K., Baba, Y., Ishimoto, T., Harada, K., Nakamura, K., Ohuchi, M., Kiyozumi, Y., Izumi, D., Tokunaga, R., Taki, K., Higashi, T., Miyata, T., Shigaki, H., Kurashige, J., Hiyoshi, Y., Iwatsuki, M., Iwagami, S., Sakamoto, Y., Miyamoto, Y., Yoshida, N. & 3 others, Oki, E., Watanabe, M. & Baba, H., Mar 1 2016, In: Medical Oncology. 33, 3, p. 1-9 9 p., 26.

  Research output: Contribution to journal › Article › peer-review

  • Esophageal Squamous Cell Carcinoma
  • Long Interspersed Nucleotide Elements
  • Mutation
  • Methylation
  • APOBEC Deaminases
  10 Citations (Scopus)

• A prospective study of XELOX plus bevacizumab as first-line therapy in Japanese patients with metastatic colorectal cancer (KSCC 0902)

  Ogata, Y., Shimokawa, M., Tanaka, T., Emi, Y., Oki, E., Saeki, H., Sadanaga, N., Kusumoto, T., Touyama, T., Kimura, M., Baba, H., Akagi, Y., Shirouzu, K. & Maehara, Y., Apr 1 2016, In: International Journal of Clinical Oncology. 21, 2, p. 335-343 9 p.

  Research output: Contribution to journal › Article › peer-review

  • XELOX
  • Bevacizumab
  • Colorectal Neoplasms
  • Prospective Studies
  • Confidence Intervals
  8 Citations (Scopus)

• A randomized phase III trial comparing S-1 versus UFT as adjuvant chemotherapy for stage II/III rectal cancer (JFMC35-C1: ACTS-RC)

  Oki, E., Murata, A., Yoshida, K., Maeda, K., Ikejiri, K., Munemoto, Y., Sasaki, K., Matsuda, C., Kotake, M., Suenaga, T., Matsuda, H., Emi, Y., Kakeji, Y., Baba, H., Hamada, C., Saji, S. & Maehara, Y., Jul 1 2016, In: Annals of Oncology. 27, 7, p. 1266-1272 7 p., mdw162.

  Research output: Contribution to journal › Article › peer-review

  • 1-UFT protocol
  • Rectal Neoplasms
  • Adjuvant Chemotherapy
  • Confidence Intervals
  • Survival
  19 Citations (Scopus)

• Autophagy inhibition dysregulates TBK1 signaling and promotes pancreatic inflammation

  Yang, S., Imamura, Y., Jenkins, R. W., Canadas, I., Kitajima, S., Aref, A., Brannon, A., Oki, E., Castoreno, A., Zhu, Z., Thai, T., Reibel, J., Qian, Z., Ogino, S., Kwong, K., Baba, H., Kimmelman, A. C., Magliano, M. P. D. & Barbie, D. A., Jun 2016, In: Cancer Immunology Research. 4, 6, p. 520-530 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Autophagy
  • Inflammation
  • N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide
  • Neutrophils
  • Phosphotransferases
  36 Citations (Scopus)

• Biological and clinical significance of loss of heterozygosity at the INPP4B gene locus in Japanese breast cancer

  Tokunaga, E., Yamashita, N., Kitao, H., Tanaka, K., Taketani, K., Inoue, Y., Saeki, H., Oki, E., Oda, Y. & Maehara, Y., Feb 1 2016, In: Breast. 25, p. 62-68 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Loss of Heterozygosity
  • Breast Neoplasms
  • Genes
  • Survival
  • Neoplasms
  6 Citations (Scopus)

• Blood Flow Assessment with Indocyanine Green Fluorescence Angiography for Pedicled Omental Flap on Cervical Esophagogastric Anastomosis after Esophagectomy

  Nakashima, Y., Saeki, H., Yukaya, T., Tsutsumi, S., Nakanishi, R., Sugiyama, M., Ohgaki, K., Sonoda, H., Oki, E. & Maehara, Y., May 1 2016, In: Journal of the American College of Surgeons. 222, 5, p. e67-e69

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Clinical significance of closure of mesenteric defects in laparoscopic colectomy: A single-institutional cohort study

  Sugiyama, M., Sakaguchi, Y., Oki, E., Kusumoto, E., Ota, M., Kimura, Y., Tsutsumi, N., Kusumoto, T., Ikejiri, K. & Maehara, Y., 2016, In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 26, 1, p. 82-85 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Colectomy
  • Cohort Studies
  • Reoperation
  • Ileus
  • Surgical Wound Infection
  2 Citations (Scopus)

• Clinical significance of totally laparoscopic distal gastrectomy: A comparison of short-term outcomes relative to open and laparoscopic-assisted distal gastrectomy

  Nishimura, S., Oki, E., Tsutsumi, S., Tsuda, Y., Sugiyama, M., Nakashima, Y., Sonoda, H., Ohgaki, K., Saeki, H. & Maehara, Y., Jul 1 2016, In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 26, 5, p. 372-376 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastrectomy
  • Stomach Neoplasms
  7 Citations (Scopus)

• Conversion to neuroendocrine carcinoma from squamous cell carcinoma of the esophagus after definitive chemoradiotherapy

  Morita, M., Saeki, H., Nakaji, Y., Zaitsu, Y., Hirahashi, M., Ohguri, T., Oki, E., Toh, Y., Oda, Y. & Maehara, Y., Aug 2016, In: Anticancer research. 36, 8, p. 4045-4049 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroendocrine Carcinoma
  • Chemoradiotherapy
  • Esophagus
  • Squamous Cell Carcinoma
  • Neuroendocrine Tumors
  6 Citations (Scopus)

• Current status of and perspectives regarding neoadjuvant chemoradiotherapy for locally advanced esophageal squamous cell carcinoma

  Saeki, H., Nakashima, Y., Zaitsu, Y., Tsuda, Y., Kasagi, Y., Ando, K., Imamura, Y., Ohgaki, K., Ito, S., Kimura, Y., Egashira, A., Oki, E., Morita, M. & Maehara, Y., Mar 1 2016, In: Surgery today. 46, 3, p. 261-267 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Esophageal Squamous Cell Carcinoma
  • Chemoradiotherapy
  • Esophagectomy
  • Survival
  • Neoadjuvant Therapy
  7 Citations (Scopus)

• Diagnosis of early colorectal cancer invasion depth by quantitative evaluation of the basal indentation in CT colonography

  Miyasaka, M., Tsurumaru, D., Nishimuta, Y., Asayama, Y., Kawanami, S., Oki, E., Hirahashi, M. & Honda, H., Dec 1 2016, In: Japanese Journal of Radiology. 34, 12, p. 786-794 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Computed Tomographic Colonography
  • Evaluation Studies
  • Colorectal Neoplasms
  • Enema
  • Computer-Assisted Image Processing

• Differentiation of early gastric cancer with ulceration and resectable advanced gastric cancer using multiphasic dynamic multidetector CT

  Tsurumaru, D., Miyasaka, M., Nishimuta, Y., Asayama, Y., Nishie, A., Kawanami, S., Oki, E., Hirahashi, M. & Honda, H., May 1 2016, In: European Radiology. 26, 5, p. 1330-1337 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Stomach Neoplasms
  • Contrast Media
  • Ulcer
  • Retrospective Studies
  • Injections
  21 Citations (Scopus)

• Effect of EGFR and p-AKT Overexpression on Chromosomal Instability in Gastric Cancer

  Hisamatsu, Y., Oki, E., Otsu, H., Ando, K., Saeki, H., Tokunaga, E., Aishima, S., Morita, M., Oda, Y. & Maehara, Y., Jun 1 2016, In: Annals of Surgical Oncology. 23, 6, p. 1986-1992 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Chromosomal Instability
  • ErbB Receptors
  • Stomach Neoplasms
  • Aneuploidy
  • human ERBB2 protein
  6 Citations (Scopus)

• Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study

  KYUSHU STUDY GROUP OF CLINICAL CANCER (KSCC), Feb 1 2016, In: European Journal of Surgical Oncology. 42, 2, p. 184-189 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Multicenter Studies
  • Surgeons
  • Neoplasm Metastasis
  • Drug Therapy
  • Liver
  10 Citations (Scopus)

• Evolving 5-fluorouracil therapy to achieve enhanced efficacy-past and current efforts of researchers

  Maehara, Y., Oki, E., Saeki, H., Tokunaga, E., Kitao, H., Iimori, M., Niimi, S., Kataoka, Y., Emi, Y., Kakeji, Y., Baba, H. & Shirasaka, T., Jul 2016, In: Japanese Journal of Cancer and Chemotherapy. 43, 7, p. 845-854 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Fluorouracil
  • Research Personnel
  • Tegafur
  • Prodrugs
  • potassium oxonate
  1 Citation (Scopus)

• Expression of APOBEC3B mRNA in primary breast cancer of Japanese women

  Tokunaga, E., Yamashita, N., Tanaka, K., Inoue, Y., Akiyoshi, S., Saeki, H., Oki, E., Kitao, H. & Maehara, Y., Dec 2016, In: PloS one. 11, 12, e0168090.

  Research output: Contribution to journal › Article › peer-review

  • APOBEC Deaminases
  • apolipoprotein B
  • breast neoplasms
  • polypeptides
  • Breast Neoplasms
  9 Citations (Scopus)

• Expression of PD-L1 and HLA Class I in Esophageal Squamous Cell Carcinoma: Prognostic Factors for Patient Outcome

  Ito, S., Okano, S., Morita, M., Saeki, H., Tsutsumi, S., Tsukihara, H., Nakashima, Y., Ando, K., Imamura, Y., Ohgaki, K., Oki, E., Kitao, H., Mimori, K. & Maehara, Y., Aug 2016, In: Annals of Surgical Oncology. 23, Suppl 4, p. 508-515 8 p.

  Research output: Contribution to journal › Article › peer-review

  • B7-H1 Antigen
  • Esophageal Squamous Cell Carcinoma
  • HLA Antigens
  • Survival
  • Recurrence

• Expression of PD-L1 and HLA Class I in Esophageal Squamous Cell Carcinoma: Prognostic Factors for Patient Outcome

  Ito, S., Okano, S., Morita, M., Saeki, H., Tsutsumi, S., Tsukihara, H., Nakashima, Y., Ando, K., Imamura, Y., Ohgaki, K., Oki, E., Kitao, H., Mimori, K. & Maehara, Y., Aug 1 2016, In: Annals of Surgical Oncology. 23, p. 508-515 8 p.

  Research output: Contribution to journal › Article › peer-review

  • B7-H1 Antigen
  • Esophageal Squamous Cell Carcinoma
  • HLA Antigens
  • Survival
  • Recurrence
  26 Citations (Scopus)

• Expression of the anaphylatoxin C5a receptor in gastric cancer: implications for vascular invasion and patient outcomes

  Nitta, H., Shimose, T., Emi, Y., Imamura, T., Ohnishi, K., Kusumoto, T., Yamamoto, M., Fukuzawa, K., Takahashi, I., Higashi, H., Tsuji, A., Akagi, Y., Oki, E., Maehara, Y., Baba, H. & Kyushu Study Group of Clinical Cancer (KSCC) ancillary study, S. G. O. C. C. KSCC. A. S., Nov 1 2016, In: Medical Oncology. 33, 11, 118.

  Research output: Contribution to journal › Article › peer-review

  • Anaphylatoxin C5a Receptor
  • Stomach Neoplasms
  • Blood Vessels
  • Neoplasms
  • Liver
  5 Citations (Scopus)

• Fibroblast growth factor receptor 2 expression, but not its genetic amplification, is associated with tumor growth and worse survival in esophagogastric junction adenocarcinoma

  Tokunaga, R., Imamura, Y., Nakamura, K., Ishimoto, T., Nakagawa, S., Miyake, K., Nakaji, Y., Tsuda, Y., Iwatsuki, M., Baba, Y., Sakamoto, Y., Miyamoto, Y., Saeki, H., Yoshida, N., Oki, E., Watanabe, M., Oda, Y., Bass, A. J., Maehara, Y. & Baba, H., Apr 12 2016, In: Oncotarget. 7, 15, p. 19748-19761 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Fibroblast Growth Factor, Type 2
  • Esophagogastric Junction
  • Adenocarcinoma
  • Survival
  • Growth
  16 Citations (Scopus)

• Gastric Cancer Patients with High PLK1 Expression and DNA Aneuploidy Correlate with Poor Prognosis

  Otsu, H., Iimori, M., Ando, K., Saeki, H., Aishima, S., Oda, Y., Morita, M., Matsuo, K., Kitao, H., Oki, E. & Maehara, Y., Jul 1 2016, In: Oncology (Switzerland). 91, 1, p. 31-40 10 p.

  Research output: Contribution to journal › Article › peer-review

  • polo-like kinase 1
  • Aneuploidy
  • Stomach Neoplasms
  • DNA
  • Ploidies
  18 Citations (Scopus)

• Genomic landscape of colorectal cancer in Japan: Clinical implications of comprehensive genomic sequencing for precision medicine

  Nagahashi, M., Wakai, T., Shimada, Y., Ichikawa, H., Kameyama, H., Kobayashi, T., Sakata, J., Yagi, R., Sato, N., Kitagawa, Y., Uetake, H., Yoshida, K., Oki, E., Kudo, S. E., Izutsu, H., Kodama, K., Nakada, M., Tse, J., Russell, M., Heyer, J. & 8 others, Powers, W., Sun, R., Ring, J. E., Takabe, K., Protopopov, A., Ling, Y., Okuda, S. & Lyle, S., Dec 22 2016, In: Genome Medicine. 8, 1, 136.

  Research output: Contribution to journal › Article › peer-review

  • Precision Medicine
  • Japan
  • Colorectal Neoplasms
  • Mutation
  • Genes
  40 Citations (Scopus)

• High expression of the Notch ligand Jagged-1 is associated with poor prognosis after surgery for colorectal cancer

  Sugiyama, M., Oki, E., Nakaji, Y., Tsutsumi, S., Ono, N., Nakanishi, R., Sugiyama, M., Nakashima, Y., Sonoda, H., Ohgaki, K., Yamashita, N., Saeki, H., Okano, S., Kitao, H., Morita, M., Oda, Y. & Maehara, Y., Nov 1 2016, In: Cancer Science. 107, 11, p. 1705-1716 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Jagged-1 Protein
  • Colorectal Neoplasms
  • Ligands
  • Cadherins
  • Epithelial-Mesenchymal Transition
  15 Citations (Scopus)

• Impact of Expression of Vimentin and Axl in Breast Cancer

  Tanaka, K., Tokunaga, E., Inoue, Y., Yamashita, N., Saeki, H., Okano, S., Kitao, H., Oki, E., Oda, Y. & Maehara, Y., Dec 1 2016, In: Clinical Breast Cancer. 16, 6, p. 520-526.e2

  Research output: Contribution to journal › Article › peer-review

  • Vimentin
  • Breast Neoplasms
  • Triple Negative Breast Neoplasms
  • Survival
  • axl receptor tyrosine kinase
  13 Citations (Scopus)

• Incidence of Venous Thromboembolism Following Laparoscopic Surgery for Gastrointestinal Cancer: A Single-Center, Prospective Cohort Study

  Kimura, Y., Oki, E., Ando, K., Saeki, H., Kusumoto, T. & Maehara, Y., Feb 1 2016, In: World journal of surgery. 40, 2, p. 309-314 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastrointestinal Neoplasms
  • Venous Thromboembolism
  • Laparoscopy
  • Cohort Studies
  • Prospective Studies
  20 Citations (Scopus)

• Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution

  Uchi, R., Takahashi, Y., Niida, A., Shimamura, T., Hirata, H., Sugimachi, K., Sawada, G., Iwaya, T., Kurashige, J., Shinden, Y., Iguchi, T., Eguchi, H., Chiba, K., Shiraishi, Y., Nagae, G., Yoshida, K., Nagata, Y., Haeno, H., Yamamoto, H., Ishii, H. & 21 others, Doki, Y., Iinuma, H., Sasaki, S., Nagayama, S., Yamada, K., Yachida, S., Kato, M., Shibata, T., Oki, E., Saeki, H., Shirabe, K., Oda, Y., Maehara, Y., Komune, S., Mori, M., Suzuki, Y., Yamamoto, K., Aburatani, H., Ogawa, S., Miyano, S. & Mimori, K., Feb 2016, In: PLoS genetics. 12, 2, e1005778.

  Research output: Contribution to journal › Article › peer-review

  • colorectal neoplasms
  • cancer
  • Colorectal Neoplasms
  • Genetic Drift
  • tumor
  64 Citations (Scopus)

• Laparoscopic resection of gastric cancer in a patient with chronic lymphocytic leukemia accompanied by neutropenia

  Nakashima, Y., Nakanishi, R., Sugiyama, M., Ohgaki, K., Sonoda, H., Saeki, H., Oki, E., Matsuyama, A., Maeda, T., Tsutsui, S., Matsuda, H., Ishida, T. & Maehara, Y., Apr 2016, In: Anticancer research. 36, 4, p. 1779-1783 5 p.

  Research output: Contribution to journal › Article › peer-review

  • B-Cell Chronic Lymphocytic Leukemia
  • Gastrectomy
  • T-Cell Prolymphocytic Leukemia
  • Neutropenia
  • Stomach Neoplasms

• Lysine-specific demethylase-1 contributes to malignant behavior by regulation of invasive activity and metabolic shift in esophageal cancer

  Kosumi, K., Baba, Y., Sakamoto, A., Ishimoto, T., Harada, K., Nakamura, K., Kurashige, J., Hiyoshi, Y., Iwatsuki, M., Iwagami, S., Sakamoto, Y., Miyamoto, Y., Yoshida, N., Oki, E., Watanabe, M., Hino, S., Nakao, M. & Baba, H., Jan 15 2016, In: International Journal of Cancer. 138, 2, p. 428-439 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Esophageal Neoplasms
  • Lysine
  • Oxygen Consumption
  • Respiration
  • human KDM1A protein
  15 Citations (Scopus)

• Mixed spindle and epithelioid cell type gastrointestinal stromal tumor of the esophagus: a case report

  Korehisa, S., Saeki, H., Nakashima, Y., Nakaji, Y., Tsutsumi, S., Yukaya, T., Tajiri, H., Kasagi, Y., Sonoda, H., Sugiyama, M., Ohgaki, K., Oki, E., Hirahashi, M., Yamamoto, H. & Maehara, Y., Jul 1 2016, In: Esophagus. 13, 3, p. 301-305 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelioid Cells
  • Gastrointestinal Stromal Tumors
  • Esophagus
  • Hematemesis
  • Biopsy

• Multicenter phase II study of combination therapy with cetuximab and S-1 in patients with KRAS exon 2 wild-type unresectable colorectal cancer previously treated with irinotecan, oxaliplatin, and fluoropyrimidines (KSCC 0901 study)

  Takahashi, T., Emi, Y., Oki, E., Kobayashi, K., Tsuji, A., Shimokawa, M., Tanaka, T., Akagi, Y., Ogata, Y., Baba, H., Yoshida, K., Natsugoe, S., Maehara, Y. & Kyushu Study Group of Clinical Cancer (KSCC), S. G. O. C. C. KSCC., Sep 1 2016, In: Cancer chemotherapy and pharmacology. 78, 3, p. 585-593 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cetuximab
  • Oxaliplatin
  • Irinotecan
  • Exons
  • Colorectal Neoplasms
  3 Citations (Scopus)

• Oxaliplatin - A 10-year trajectory

  Kanaji, S., Oki, E., Saeki, H., Kitao, H., Maehara, Y. & Kakeji, Y., Jun 2016, In: Japanese Journal of Cancer and Chemotherapy. 43, 6, p. 715-722 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • antineoplaston A10
  • Oxaliplatin
  • 1,2-cyclohexanediamine
  • Platinum
  • Japan

• Peritoneal dissemination requires an Sp1-dependent CXCR4/CXCL12 signaling axis and extracellular matrix-directed spheroid formation

  Kasagi, Y., Harada, Y., Morodomi, Y., Iwai, T., Saito, S., Yoshida, K., Oki, E., Saeki, H., Ohgaki, K., Sugiyama, M., Onimaru, M., Maehara, Y. & Yonemitsu, Y., Jan 15 2016, In: Cancer Research. 76, 2, p. 347-357 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Matrix
  • Peritoneal Cavity
  • Neoplasms
  • Peritoneal Lavage
  • Gastrointestinal Neoplasms
  14 Citations (Scopus)

• Phase II trial of an alternating regimen consisting of first-line mFOLFOX6 plus bevacizumab and FOLFIRI plus bevacizumab for patients with metastatic colorectal cancer: FIREFOX plus bevacizumab trial (KSCC0801)

  Miwa, K., Oki, E., Emi, Y., Saeki, H., Kusumoto, T., Akagi, Y., Ogata, Y., Samura, H., Tokunaga, S., Ishikawa, H., Tanaka, T., Sueyoshi, S., Higashi, H., Matsuda, H., Touyama, T. & Maehara, Y., Feb 1 2016, In: International Journal of Clinical Oncology. 21, 1, p. 110-117 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Leucovorin
  • Irinotecan
  • Bevacizumab
  • Fluorouracil
  • Colorectal Neoplasms
  7 Citations (Scopus)

• Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability

  Iimori, M., Watanabe, S., Kiyonari, S., Matsuoka, K., Sakasai, R., Saeki, H., Oki, E., Kitao, H. & Maehara, Y., Mar 31 2016, In: Nature communications. 7, 11117.

  Research output: Contribution to journal › Article › peer-review

  • Phosphorylation
  • phosphorylation
  • genome
  • progressions
  • Genomic Instability
  14 Citations (Scopus)

• Real-Time Accurate Identification of Tumor Site Using a Mobile X-Ray Image-Intensifier System during Laparoscopic Gastrectomy

  Imamura, Y., Oki, E., Ohgaki, K., Nakashima, Y., Ando, K., Tsutsumi, S., Tsurumaru, D., Saeki, H., Baba, H. & Maehara, Y., Feb 1 2016, In: Journal of the American College of Surgeons. 222, 2, p. e1-e7

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Recent Advances in Systemic Chemotherapy for Metastatic Colorectal Cancer

  Miyamoto, Y., Oki, E., Saeki, H., Maehara, Y. & Baba, H., Jan 1 2016, In: Gan to kagaku ryoho. Cancer & chemotherapy. 43, 1, p. 15-23 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Colorectal Neoplasms
  • Drug Therapy
  • trifluridine tipiracil
  • regorafenib
  • Salvage Therapy
  2 Citations (Scopus)

• Reduced MUTYH, MTH1, and OGG1 expression and TP53 mutation in diffuse-type adenocarcinoma of gastric cardia

  Kohno, Y., Yamamoto, H., Hirahashi, M., Kumagae, Y., Nakamura, M., Oki, E. & Oda, Y., Jun 1 2016, In: Human Pathology. 52, p. 145-152 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cardia
  • Adenocarcinoma
  • Stomach
  • Mutation
  • Pylorus
  8 Citations (Scopus)

• S-1 and irinotecan plus bevacizumab as second-line chemotherapy for patients with oxaliplatin-refractory metastatic colorectal cancer: a multicenter phase II study in Japan (KSCC1102)

  Miyamoto, Y., Tsuji, A., Tanioka, H., Maekawa, S., Kawanaka, H., Kitazono, M., Oki, E., Emi, Y., Murakami, H., Ogata, Y., Saeki, H., Shimokawa, M., Natsugoe, S., Akagi, Y., Baba, H. & Maehara, Y., Aug 1 2016, In: International Journal of Clinical Oncology. 21, 4, p. 705-712 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxaliplatin
  • Irinotecan
  • Bevacizumab
  • Japan
  • S 1 (combination)
  4 Citations (Scopus)

• Surgical treatment of liver metastasis of gastric cancer: a retrospective multicenter cohort study (KSCC1302)

  Oki, E., Tokunaga, S., Emi, Y., Kusumoto, T., Yamamoto, M., Fukuzawa, K., Takahashi, I., Ishigami, S., Tsuji, A., Higashi, H., Nakamura, T., Saeki, H., Shirabe, K., Kakeji, Y., Sakai, K., Baba, H., Nishimaki, T., Natsugoe, S. & Maehara, Y., Jul 1 2016, In: Gastric Cancer. 19, 3, p. 968-976 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Multicenter Studies
  • Stomach Neoplasms
  • Cohort Studies
  • Neoplasm Metastasis
  • Liver
  60 Citations (Scopus)

• The antibodies against 5-bromo-2′-deoxyuridine specifically recognize trifluridine incorporated into DNA

  Kitao, H., Morodomi, Y., Niimi, S., Kiniwa, M., Shigeno, K., Matsuoka, K., Kataoka, Y., Iimori, M., Tokunaga, E., Saeki, H., Oki, E. & Maehara, Y., May 3 2016, In: Scientific reports. 6, 25286.

  Research output: Contribution to journal › Article › peer-review

  • Trifluridine
  • trifluridine tipiracil
  • Bromodeoxyuridine
  • DNA
  • Antibodies
  15 Citations (Scopus)

• The molecular aspect of the antitumor effect of oxaliplatin in combination with 5-FU

  Kitao, H., Kiyonari, S., Limori, M., Niimi, S., Kataoka, Y., Akiyama, S., Edahiro, K., Nakanishi, R., Tokunaga, E., Saeki, H., Oki, E., Kanaji, S., Kakeji, Y. & Maehara, Y., Jun 2016, In: Japanese Journal of Cancer and Chemotherapy. 43, 6, p. 707-714 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Oxaliplatin
  • Platinum
  • Fluorouracil
  • Leucovorin
  • Combination Drug Therapy
  3 Citations (Scopus)

• The Prognostic Significance of Histone Lysine Demethylase JMJD3/KDM6B in Colorectal Cancer

  Tokunaga, R., Sakamoto, Y., Nakagawa, S., Miyake, K., Izumi, D., Kosumi, K., Taki, K., Higashi, T., Imamura, Y., Ishimoto, T., Iwatsuki, M., Baba, Y., Miyamoto, Y., Yoshida, N., Oki, E., Watanabe, M. & Baba, H., Feb 1 2016, In: Annals of Surgical Oncology. 23, 2, p. 678-685 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Histone Demethylases
  • Colorectal Neoplasms
  • Lysine
  • Histones
  • Cell Cycle
  26 Citations (Scopus)
• 2017

  Actionable gene-based classification toward precision medicine in gastric cancer

  Ichikawa, H., Nagahashi, M., Shimada, Y., Hanyu, T., Ishikawa, T., Kameyama, H., Kobayashi, T., Sakata, J., Yabusaki, H., Nakagawa, S., Sato, N., Hirata, Y., Kitagawa, Y., Tanahashi, T., Yoshida, K., Nakanishi, R., Oki, E., Vuzman, D., Lyle, S., Takabe, K. & 4 others, Ling, Y., Okuda, S., Akazawa, K. & Wakai, T., Oct 31 2017, In: Genome Medicine. 9, 1, 93.

  Research output: Contribution to journal › Article › peer-review

  • Precision Medicine
  • Stomach Neoplasms
  • Genes
  • Microsatellite Instability
  • Atlases
  24 Citations (Scopus)

• Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells

  Ishimoto, T., Miyake, K., Nandi, T., Yashiro, M., Onishi, N., Huang, K. K., Lin, S. J., Kalpana, R., Tay, S. T., Suzuki, Y., Cho, B. C., Kuroda, D., Arima, K., Izumi, D., Iwatsuki, M., Baba, Y., Oki, E., Watanabe, M., Saya, H., Hirakawa, K. & 2 others, Baba, H. & Tan, P., Jul 2017, In: Gastroenterology. 153, 1, p. 191-204.e16

  Research output: Contribution to journal › Article › peer-review

  • Cancer-Associated Fibroblasts
  • Transforming Growth Factor beta
  • Stomach Neoplasms
  • Fibroblasts
  • Nude Mice
  61 Citations (Scopus)

• Adjuvant capecitabine plus oxaliplatin after D2 gastrectomy in Japanese patients with gastric cancer: a phase II study

  Fuse, N., Bando, H., Chin, K., Ito, S., Yoshikawa, T., Tsuburaya, A., Terashima, M., Kawashima, Y., Fukunaga, T., Gotoh, M., Emi, Y., Yoshida, K., Oki, E., Takahashi, S., Kuriki, H., Sato, K. & Sasako, M., Mar 1 2017, In: Gastric Cancer. 20, 2, p. 332-340 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Capecitabine
  • Oxaliplatin
  • XELOX
  • Gastrectomy
  • Stomach Neoplasms
  36 Citations (Scopus)

• A locally advanced breast cancer that achieved pCR with pertuzumab, trastuzumab and docetaxel: Case report

  Inoue, Y., Yamashita, N., Tokunaga, E., Tanaka, K., Ueo, H., Saeki, H., Oki, E., Yamamoto, H. & Maehara, Y., Apr 2017, In: Anticancer research. 37, 4, p. 1917-1921 5 p.

  Research output: Contribution to journal › Article › peer-review

  • pertuzumab
  • Trastuzumab
  • Docetaxel
  • human ERBB2 protein
  • Breast Neoplasms
  1 Citation (Scopus)

• Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer

  Nambara, S., Masuda, T., Nishio, M., Kuramitsu, S., Tobo, T., Ogawa, Y., Hu, Q., Iguchi, T., Kuroda, Y., Ito, S., Eguchi, H., Sugimachi, K., Saeki, H., Oki, E., Maehara, Y., Suzuki, A. & Mimori, K., Dec 8 2017, In: Oncotarget. 8, 64, p. 107666-107677 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Antiparasitic Agents
  • Ivermectin
  • Stomach Neoplasms
  • Proteins
  • Heterografts

• Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer

  Nambara, S., Masuda, T., Nishio, M., Kuramitsu, S., Tobo, T., Ogawa, Y., Hu, Q., Iguchi, T., Kuroda, Y., Ito, S., Eguchi, H., Sugimachi, K., Saeki, H., Oki, E., Maehara, Y., Suzuki, A. & Mimori, K., 2017, In: Oncotarget. 8, 64, p. 107666-107677 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Antiparasitic Agents
  • Ivermectin
  • Stomach Neoplasms
  • Proteins
  • Heterografts
  14 Citations (Scopus)

• A phase II study of FOLFOXIRI with bevacizumab in untreated metastatic colorectal cancer patients: A UGT1A1 genotype and safety results (QUATTRO study)

  Kato, T., Yoshino, T., Muro, K., Yamazaki, K., Yamaguchi, T., Oki, E., Iwamoto, S., Tsuji, A., Nakayama, G., Emi, Y., Touyama, T., Nakamura, M., Kotaka, M., Bando, H., Kagawa, Y., Taniguchi, H., Yamanaka, T. & Kanazawa, A., Jun 1 2017, In: Annals of oncology : official journal of the European Society for Medical Oncology. 28, p. iii9-iii10

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)