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• Article

  A novel anti-microtubule agent with carbazole and benzohydrazide structures suppresses tumor cell growth in vivo

  Ohira, M., Iwasaki, Y., Tanaka, C., Kuroki, M., Matsuo, N., Kitamura, T., Yukuhiro, M., Morimoto, H., Pang, N., Liu, B., Kiyono, T., Amemiya, M., Tanaka, K., Yoshida, K., Sugimoto, N., Ohshima, T. & Fujita, M., May 19 2015, In: Biochimica et Biophysica Acta - General Subjects. 1850, 9, p. 1676-1684 9 p.

  Research output: Contribution to journal › Article › peer-review

  • carbazole
  • Cell growth
  • Tumors
  • Cells
  • Microtubules
  6 Citations (Scopus)

• ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication

  Iwahori, S., Kohmon, D., Kobayashi, J., Tani, Y., Yugawa, T., Komatsu, K., Kiyono, T., Sugimoto, N. & Fujita, M., Feb 1 2014, In: Cell Cycle. 13, 3, p. 471-481 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ataxia Telangiectasia
  • S Phase
  • Double-Stranded DNA Breaks
  • Genomic Instability
  • Ligases
  8 Citations (Scopus)

• CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells

  Yoshida, K., Sugimoto, N., Iwahori, S., Yugawa, T., Narisawa-Saito, M., Kiyono, T. & Fujita, M., 2010, In: Journal of cell science. 123, 2, p. 225-235 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Eukaryotic Cells
  • Xenopus
  • Phosphorylation
  • S Phase
  • Chromatin
  21 Citations (Scopus)

• Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture

  Sugimoto, N., Maehara, K., Yoshida, K., Yasukouchi, S., Osano, S., Watanabe, S., Aizawa, M., Yugawa, T., Kiyono, T., Kurumizaka, H., Ohkawa, Y. & Fujita, M., 2015, In: Nucleic acids research. 43, 12, p. 5898-5911 14 p.

  Research output: Contribution to journal › Article › peer-review

  • WD40 Repeats
  • Histones
  • Chromatin
  • Glutamic Acid
  • Carrier Proteins
  26 Citations (Scopus)

• Generation of a monoclonal antibody for INI1/hSNF5/BAF47

  Harada, A., Hayashi, M., Kuniyoshi, Y., Semba, Y., Sugahara, S., Tachibana, T., Ohkawa, Y. & Fujita, M., Feb 1 2014, In: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33, 1, p. 49-51 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Differentiation
  • Monoclonal Antibodies
  • Chromatin Assembly and Disassembly
  • Antibodies
  • Gene Expression Regulation

• Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

  Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., 2018, In: Nucleic acids research. 46, 13, p. 6683-6696 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Spatio-Temporal Analysis
  • Replication Origin
  • Chromatin
  • Transcription Initiation Site
  • Genome
  17 Citations (Scopus)

• Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

  Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., Jul 27 2018, In: Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Spatio-Temporal Analysis
  • Replication Origin
  • Chromatin
  • Transcription Initiation Site
  • Genome

• GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

  Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., Aug 1 2018, In: Journal of cell science. 131, 15

  Research output: Contribution to journal › Article › peer-review

  • WD40 Repeats
  • Ribosomal Proteins
  • Proteasome Endopeptidase Complex
  • Ubiquitin
  • Glutamic Acid
  5 Citations (Scopus)

• Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10

  Yokoyama, T., Yukuhiro, M., Iwasaki, Y., Tanaka, C., Sankoda, K., Fujiwara, R., Shibuta, A., Higashi, T., Motoyama, K., Arima, H., Yoshida, K., Sugimoto, N., Morimoto, H., Kosako, H., Ohshima, T. & Fujita, M., Dec 1 2019, In: Scientific reports. 9, 1, 16825.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • polyoxyethylene(10)nonylphenyl ether
  • Antimitotic Agents
  • Antineoplastic Agents
  • carbazole
  • Karyopherins

• Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib

  Morii, I., Iwabuchi, Y., Mori, S., Suekuni, M., Natsume, T., Yoshida, K., Sugimoto, N., Kanemaki, M. T. & Fujita, M., Mar 2019, In: Cancer Science. 110, 3, p. 1044-1053 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • olaparib
  • Cisplatin
  • Platinum Compounds
  • Poly(ADP-ribose) Polymerase Inhibitors
  • Neoplasms
  4 Citations (Scopus)

• Noncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation

  Yugawa, T., Nishino, K., Ohno, S. I., Nakahara, T., Fujita, M., Goshima, N., Umezawa, A. & Kiyono, T., Nov 15 2013, In: Molecular and cellular biology. 33, 22, p. 4434-4447 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Induced Pluripotent Stem Cells
  • Keratinocytes
  • Y 27632
  • Pluripotent Stem Cells
  • Monomeric GTP-Binding Proteins
  33 Citations (Scopus)

• Sensitive detection of fluorescence in western blotting by merging images

  Kondo, Y., Higa, S., Iwasaki, T., Matsumoto, T., Maehara, K., Harada, A., Baba, Y., Fujita, M. & Ohkawa, Y., Jan 2018, In: PloS one. 13, 1, e0191532.

  Research output: Contribution to journal › Article › peer-review

  • Fluorescence
  • Merging
  • Western blotting
  • fluorescence
  • Chemiluminescence
  8 Citations (Scopus)

• ΔNp63α repression of the Notch1 gene supports the proliferative capacity of normal human keratinocytes and cervical cancer cells

  Yugawa, T., Narisawa-Saito, M., Yoshimatsu, Y., Haga, K., Ohno, S. I., Egawa, N., Fujita, M. & Kiyono, T., May 15 2010, In: Cancer Research. 70, 10, p. 4034-4044 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Keratinocytes
  • Uterine Cervical Neoplasms
  • Genes
  • Differentiation Antigens
  • p53 Genes
  41 Citations (Scopus)