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  • Noriko Isobe
2020

A case of overlapping adult-onset linear scleroderma and Parry-Romberg syndrome presenting with widespread ipsilateral neurogenic involvement

Yamasaki, R., Yonekawa, T., Inamizu, S., Shinoda, K., Ochi, H., Matsushita, T., Isobe, N., Tsuji, G., Sadashima, S., Kuma, Y., Oda, Y., Iwaki, T., Furue, M. & Kira, J. I., Feb 1 2020, In : Neuropathology. 40, 1, p. 109-115 7 p.

Research output: Contribution to journalArticle

Central nervous system-specific antinuclear antibodies in patients with multiple sclerosis

Fujii, T., Yamasaki, R., Miyachi, Y., Nagata, S., Maimaitijiang, G., Nakamura, Y., Shinoda, K., Matsushita, T., Isobe, N. & Kira, J. I., Feb 15 2020, In : Journal of the Neurological Sciences. 409, 116619.

Research output: Contribution to journalArticle

Environmental risk factors for multiple sclerosis in Japanese people

Sakoda, A., Matsushita, T., Nakamura, Y., Watanabe, M., Shinoda, K., Masaki, K., Isobe, N., Yamasaki, R. & Kira, J. I., Feb 2020, In : Multiple Sclerosis and Related Disorders. 38, 101872.

Research output: Contribution to journalArticle

Oligodendroglial connexin 47 regulates neuroinflammation upon autoimmune demyelination in a novel mouse model of multiple sclerosis

Zhao, Y., Yamasaki, R., Yamaguchi, H., Nagata, S., Une, H., Cui, Y., Masaki, K., Nakamuta, Y., Iinuma, K., Watanabe, M., Matsushita, T., Isobe, N. & Kira, J. I., Jan 28 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2160-2169 10 p.

Research output: Contribution to journalArticle

Spinal cord involvement by atrophy and associations with disability are different between multiple sclerosis and neuromyelitis optica spectrum disorder

Nakamura, Y., Liu, Z., Fukumoto, S., Shinoda, K., Sakoda, A., Matsushita, T., Hayashida, S., Isobe, N., Watanabe, M., Hiwatashi, A., Yamasaki, R. & Kira, J. I., Jan 1 2020, In : European Journal of Neurology. 27, 1, p. 92-99 8 p.

Research output: Contribution to journalArticle

Unique HLA haplotype associations in IgG4 anti-neurofascin 155 antibody-positive chronic inflammatory demyelinating polyneuropathy

Ogata, H., Isobe, N., Zhang, X., Yamasaki, R., Fujii, T., Machida, A., Morimoto, N., Kaida, K., Masuda, T., Ando, Y., Kuwahara, M., Kusunoki, S., Nakamura, Y., Matsushita, T. & Kira, J. I., Feb 15 2020, In : Journal of Neuroimmunology. 339, 577139.

Research output: Contribution to journalArticle

2018

Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients

MS-EPIC Study Group, Mar 7 2018, In : Journal of neuroinflammation. 15, 1, 72.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression

Nakamura, Y., Gaetano, L., Matsushita, T., Anna, A., Sprenger, T., Radue, E. W., Wuerfel, J., Bauer, L., Amann, M., Shinoda, K., Isobe, N., Yamasaki, R., Saida, T., Kappos, L. & Kira, J. I., Sep 5 2018, In : Journal of neuroinflammation. 15, 1, 255.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Association of decreased percentage of Vδ2+Vγ9+ γδ T cells with disease severity in multiple sclerosis

Maimaitijiang, G., Shinoda, K., Nakamura, Y., Masaki, K., Matsushita, T., Isobe, N., Yamasaki, R., Yoshikai, Y. & Kira, J. I., Apr 10 2018, In : Frontiers in Immunology. 9, APR, 748.

Research output: Contribution to journalArticle

2 Citations (Scopus)
6 Citations (Scopus)

Emerging importance of big data in neuroimmunological research

Isobe, N., Feb 1 2018, In : Clinical and Experimental Neuroimmunology. 9, 1, 1 p.

Research output: Contribution to journalEditorial

Genetics in multiple sclerosis: Updates in the era of big data

Isobe, N., Feb 1 2018, In : Clinical and Experimental Neuroimmunology. 9, 1, p. 19-24 6 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Oral phase dysphagia in facial onset sensory and motor neuronopathy

Watanabe, M., Shiraishi, W., Yamasaki, R., Isobe, N., Sawatsubashi, M., Yasumatsu, R., Nakagawa, T. & Kira, J. I., Jun 2018, In : Brain and Behavior. 8, 6, e00999.

Research output: Contribution to journalArticle

多地点接続症例検討遠隔会議におけるユーザー体感品質を考慮した技術的課題 (JTTA 2018 FUKUOKA 第22回日本遠隔医療学会学術大会)

Translated title of the contribution: Technical agenda considering QoE in large multiparty videoconferencing for clinical case study富松俊太, 工藤孔梨子, 森山智彦, 平井康之, 磯部紀子 & 清水周次, Oct 2018, In : 日本遠隔医療学会雑誌 = Japanese journal of telemedicine and telecare. 14, 2, p. 155-158 4 p.

Research output: Contribution to journalArticle

2017

American Academy of Neurology 2017 Annual Meeting

Isobe, N., Aug 2017, In : Clinical and Experimental Neuroimmunology. 8, 3, p. 273-275 3 p.

Research output: Contribution to journalArticle

2016

Association of HLA genetic risk burden with disease phenotypes in multiple sclerosis

Isobe, N., Keshavan, A., Gourraud, P. A., Zhu, A. H., Datta, E., Schlaeger, R., Caillier, S. J., Santaniello, A., Lizée, A., Himmelstein, D. S., Baranzini, S. E., Hollenbach, J., Cree, B. A. C., Hauser, S. L., Oksenberg, J. R. & Henry, R. G., Jul 2016, In : JAMA Neurology. 73, 7, p. 795-802 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

HLA genetic risk burden in multiple sclerosis-reply

Isobe, N., Oksenberg, J. R. & Henry, R. G., Jan 1 2016, In : JAMA Neurology. 73, 12, p. 1501-1502 2 p.

Research output: Contribution to journalLetter

Latitude and HLA-DRB1*04:05 independently influence disease severity in Japanese multiple sclerosis: A cross-sectional study

Nakamura, Y., Matsushita, T., Sato, S., Niino, M., Fukazawa, T., Yoshimura, S., Hisahara, S., Isobe, N., Shimohama, S., Watanabe, M., Yoshida, K., Houzen, H., Miyazaki, Y., Yamasaki, R., Kikuchi, S. & Kira, J. I., Sep 6 2016, In : Journal of neuroinflammation. 13, 1, 239.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2015

An ImmunoChip study of multiple sclerosis risk in African Americans

Isobe, N., Madireddy, L., Khankhanian, P., Matsushita, T., Caillier, S. J., Moré, J. M., Gourraud, P. A., McCauley, J. L., Beecham, A. H., Piccio, L., Herbert, J., Khan, O., Cohen, J., Stone, L., Santaniello, A., Cree, B. A. C., Onengut-Gumuscu, S., Rich, S. S., Hauser, S. L., Sawcer, S. & 1 others, Oksenberg, J. R., Jun 1 2015, In : Brain. 138, 6, p. 1518-1530 13 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome

Didonna, A., Isobe, N., Caillier, S. J., Li, K. H., Burlingame, A. L., Hauser, S. L., Baranzini, S. E., Patsopoulos, N. A. & Oksenberg, J. R., Jan 1 2015, In : Human Molecular Genetics. 24, 24, p. 7151-7158 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Copy number variations in multiple sclerosis and neuromyelitis optica

Sato, S., Yamamoto, K., Matsushita, T., Isobe, N., Kawano, Y., Iinuma, K., Niino, M., Fukazawa, T., Nakamura, Y., Watanabe, M., Yonekawa, T., Masaki, K., Yoshimura, S., Murai, H., Yamasaki, R. & Kira, J. I., Nov 2015, In : Annals of Neurology. 78, 5, p. 762-774 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Distinct features of immunoglobulin G2 aquaporin-4 antibody carriers with neuromyelitis optica

Isobe, N., Yonekawa, T., Matsushita, T., Kawano, Y., Masaki, K., Yoshimura, S., Murai, H., Yamasaki, R. & Kira, J-I., May 1 2015, In : Clinical and Experimental Neuroimmunology. 6, 2, p. 154-158 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Latitude and HLA-DRB1 alleles independently affect the emergence of cerebrospinal fluid IgG abnormality in multiple sclerosis

Niino, M., Sato, S., Fukazawa, T., Yoshimura, S., Hisahara, S., Matsushita, T., Isobe, N., Yoshida, K., Houzen, H., Miyazaki, Y., Shimohama, S., Kikuchi, S. & Kira, J. I., Aug 25 2015, In : Multiple Sclerosis. 21, 9, p. 1112-1120 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Whole genome sequences of 2 octogenarians with sustained cognitive abilities

Nickles, D., Madireddy, L., Patel, N., Isobe, N., Miller, B. L., Baranzini, S. E., Kramer, J. H. & Oksenberg, J. R., Mar 1 2015, In : Neurobiology of Aging. 36, 3, p. 1435-1438 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2014

A case of neuromyelitis optica harboring both anti-aquaporin-4 antibodies and a pathogenic mitochondrial DNA mutation for Leber's hereditary optic neuropathy

Shiraishi, W., Hayashi, S., Kamada, T., Isobe, N., Yamasaki, R., Murai, H., Ohyagi, Y. & Kira, J. I., Feb 1 2014, In : Multiple Sclerosis. 20, 2, p. 258-260 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A nationwide survey of hypertrophic pachymeningitis in Japan

Yonekawa, T., Murai, H., Utsuki, S., Matsushita, T., Masaki, K., Isobe, N., Yamasaki, R., Yoshida, M., Kusunoki, S., Sakata, K., Fujii, K. & Kira, J. I., Jul 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, 7, p. 732-739 8 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Decreased CCR2 and CD62L expressions on peripheral blood classical monocytes in amyotrophic lateral sclerosis

Cui, Y. W., Kawano, Y., Yamasaki, R., Shi, N., Masaki, K., Isobe, N., Yonekawa, T., Matsushita, T., Tateishi, T., Hayashi, S. & Kira, J-I., Jan 1 2014, In : Clinical and Experimental Neuroimmunology. 5, 1, p. 92-96 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genetic and infectious profiles influence cerebrospinal fluid IgG abnormality in japanese multiple sclerosis patients

Yoshimura, S., Isobe, N., Matsushita, T., Masaki, K., Sato, S., Kawano, Y., Ochi, H. & Kira, J. I., Apr 15 2014, In : PloS one. 9, 4, e95367.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Genetic and infectious profiles influence cerebrospinal fluid IgG abnormality in Japanese multiple sclerosis patients

Yoshimura, S., Isobe, N., Matsushita, T., Masaki, K., Sato, S., Kawano, Y., Ochi, H. & Kira, J. I., Jan 1 2014, In : PloS one. 9, 4, p. e95367

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)
3 Citations (Scopus)

Interleukin 2 receptor α chain gene polymorphisms and risks of multiple sclerosis and neuromyelitis optica in southern Japanese

Ainiding, G., Kawano, Y., Sato, S., Isobe, N., Matsushita, T., Yoshimura, S., Yonekawa, T., Yamasaki, R., Murai, H. & Kira, J. I., Feb 15 2014, In : Journal of the Neurological Sciences. 337, 1-2, p. 147-150 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis

Harbo, H. F., Isobe, N., Berg-Hansen, P., Bos, S. D., Caillier, S. J., Gustavsen, M. W., Mero, I. L., Celius, E. G., Hauser, S. L., Oksenberg, J. R. & Gourraud, P. A., May 2014, In : Multiple Sclerosis Journal. 20, 6, p. 660-668 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2013

Alterations in chemokine receptor expressions on peripheral blood monocytes in multiple sclerosis and neuromyelitis optica

Cui, Y. W., Kawano, Y., Shi, N., Masaki, K., Isobe, N., Yonekawa, T., Matsushita, T., Tateishi, T., Yamasaki, R., Murai, H. & Kira, J. I., Aug 1 2013, In : Clinical and Experimental Neuroimmunology. 4, 2, p. 201-205 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A NOTCH4 missense mutation confers resistance to multiple sclerosis in Japanese

Huang, J., Yoshimura, S., Isobe, N., Matsushita, T., Yonekawa, T., Sato, S., Yamasaki, R. & Kira, J. I., Nov 2013, In : Multiple Sclerosis Journal. 19, 13, p. 1696-1703 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2 Citations (Scopus)
101 Citations (Scopus)

Clinical relevance of serum aquaporin-4 antibody levels in neuromyelitis optica

Isobe, N., Yonekawa, T., Matsushita, T., Masaki, K., Yoshimura, S., Fichna, J., Chen, S., Furmaniak, J., Smith, B. R. & Kira, J. I., May 1 2013, In : Neurochemical Research. 38, 5, p. 997-1001 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Distinct genetic and infectious profiles in Japanese neuromyelitis optica patients according to anti-aquaporin 4 antibody status

Yoshimura, S., Isobe, N., Matsushita, T., Yonekawa, T., Masaki, K., Sato, S., Kawano, Y., Kira, J. I., Miyamoto, K., Kusunoki, S., Nakatsuji, Y., Mochizuki, H., Ochi, K., Matsumoto, M., Kanda, T., Ochi, H., Miki, T., Okada, K. & Tsuji, S., Jan 2013, In : Journal of Neurology, Neurosurgery and Psychiatry. 84, 1, p. 29-34 6 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Distinct genetic profiles between Japanese multiple sclerosis patients with and without Barkhof brain lesions

Huang, J., Isobe, N., Matsushita, T., Yoshimura, S., Sato, S., Yonekawa, T., Yamasaki, R., Murai, H. & Kira, J. I., Aug 1 2013, In : Clinical and Experimental Neuroimmunology. 4, 2, p. 173-180 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genetic burden in multiple sclerosis families

Isobe, N., Damotte, V., Lo Re, V., Ban, M., Pappas, D., Guillot-Noel, L., Rebeix, I., Compston, A., Mack, T., Cozen, W., Fontaine, B., Hauser, S. L., Oksenberg, J. R., Sawcer, S. & Gourraud, P. A., Aug 2 2013, In : Genes and Immunity. 14, 7, p. 434-440 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Genetic risk variants in African Americans with multiple sclerosis

Isobe, N., Gourraud, P. A., Harbo, H. F., Caillier, S. J., Santaniello, A., Khankhanian, P., Maiers, M., Spellman, S., Cereb, N., Yang, S., Pando, M. J., Piccio, L., Cross, A. H., De Jager, P. L., Cree, B. A. C., Hauser, S. L. & Oksenberg, J. R., Jul 16 2013, In : Neurology. 81, 3, p. 219-227 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Multimodality evoked potentials for discrimination of atopic myelitis and multiple sclerosis

Kanamori, Y., Isobe, N., Yonekawa, T., Matsushita, T., Shigeto, H., Kawamura, N., Yamasaki, R., Murai, H., Tobimatsu, S. & Kira, J. I., Jun 1 2013, In : Clinical and Experimental Neuroimmunology. 4, 1, p. 29-35 7 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Protein kinase C-η polymorphism rs2230500 does not confer disease susceptibility to multiple sclerosis or neuromyelitis optica

Kawano, Y., Matsushita, T., Cui, Y. W., Isobe, N., Yoshimura, S., Yonekawa, T., Masaki, K., Yamasaki, R., Murai, H. & Kira, J. I., Dec 1 2013, In : Clinical and Experimental Neuroimmunology. 4, 3, p. 283-287 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2012

Clinical disability progression and platelet GP IIb/IIIa values in patients with atopic myelitis

Ainiding, G., Yamashita, K. I., Torii, T., Furuta, K., Isobe, N., Matsushita, T., Masaki, K., Matsumoto, S. & Kira, J. I., May 15 2012, In : Journal of Neuroimmunology. 246, 1-2, p. 108-112 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
20 Citations (Scopus)

Extensive loss of connexins in Baló's disease: Evidence for an auto-antibody-independent astrocytopathy via impaired astrocyte-oligodendrocyte/ myelin interaction

Masaki, K., Suzuki, S. O., Matsushita, T., Yonekawa, T., Matsuoka, T., Isobe, N., Motomura, K., Wu, X. M., Tabira, T., Iwaki, T. & Kira, J. I., Jun 1 2012, In : Acta neuropathologica. 123, 6, p. 887-900 14 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

First diagnostic criteria for atopic myelitis with special reference to discrimination from myelitis-onset multiple sclerosis

Isobe, N., Kanamori, Y., Yonekawa, T., Matsushita, T., Shigeto, H., Kawamura, N. & Kira, J. I., May 15 2012, In : Journal of the Neurological Sciences. 316, 1-2, p. 30-35 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Genetic and Infectious Profiles of Japanese Multiple Sclerosis Patients

Yoshimura, S., Isobe, N., Yonekawa, T., Matsushita, T., Masaki, K., Sato, S., Kawano, Y., Yamamoto, K. & Kira, J. I., Nov 9 2012, In : PloS one. 7, 11, e48592.

Research output: Contribution to journalArticle

45 Citations (Scopus)

HLA-DPB1*0201 is associated with susceptibility to atopic myelitis in Japanese

Sato, S., Isobe, N., Yoshimura, S., Kanamori, Y., Masaki, K., Matsushita, T. & Kira, J. I., Oct 15 2012, In : Journal of Neuroimmunology. 251, 1-2, p. 110-113 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Quantitative assays for anti-aquaporin-4 antibody with subclass analysis in neuromyelitis optica

Isobe, N., Yonekawa, T., Matsushita, T., Kawano, Y., Masaki, K., Yoshimura, S., Fichna, J., Chen, S., Furmaniak, J., Smith, B. R. & Kira, J. I., Nov 2012, In : Multiple Sclerosis Journal. 18, 11, p. 1541-1551 11 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)