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  • Nozomu Okino
2020

Determination of globotriaosylceramide analogs in the organs of a mouse model of Fabry disease

Ishii, S., Taguchi, A., Okino, N., Ito, M. & Maruyama, H., Apr 24 2020, In : Journal of Biological Chemistry. 295, 17, p. 5577-5587 11 p.

Research output: Contribution to journalArticle

Open Access
2019
Open Access

Expression, purification, and characterization of highly active endo-α-N-acetylgalactosaminidases expressed by silkworm-baculovirus expression system

Morio, A., Xu, J., Masuda, A., Kinoshita, Y., Hino, M., Morokuma, D., Goda, H. M., Okino, N., Ito, M., Mon, H., Fujita, R., Kusakabe, T. & Lee, J. M., Jun 2019, In : Journal of Asia-Pacific Entomology. 22, 2, p. 404-408 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The glycerol-3-phosphate acyltransferase PLAT2 functions in the generation of DHA-rich glycerolipids in Aurantiochytrium limacinum F26-b

Nutahara, E., Abe, E., Uno, S., Ishibashi, Y., Watanabe, T., Hayashi, M., Okino, N. & Ito, M., Jan 2019, In : PloS one. 14, 1, e0211164.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Enhancing the sialylation of recombinant EPO produced in CHO cells via the inhibition of glycosphingolipid biosynthesis /631/1647/338/318 /631/61/318 /82/80 /82/83 article

Kwak, C. Y., Park, S. Y., Lee, C. G., Okino, N., Ito, M. & Kim, J. H., Dec 1 2017, In : Scientific reports. 7, 1, 13059.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Regulation of TG accumulation and lipid droplet morphology by the novel TLDP1 in Aurantiochytrium limacinum F26-b

Watanabe, T., Sakiyama, R., Iimi, Y., Sekine, S., Abe, E., Nomura, K. H., Nomura, K., Ishibashi, Y., Okino, N., Hayashi, M. & Ito, M., Jan 1 2017, In : Journal of Lipid Research. 58, 12, p. 2334-2347 14 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2016
3 Citations (Scopus)
6 Citations (Scopus)
2015

Ergosteryl-β-glucosidase (Egh1) involved in sterylglucoside catabolism and vacuole formation in Saccharomyces cerevisiae

Watanabe, T., Tani, M., Ishibashi, Y., Endo, I., Okino, N. & Ito, M., Apr 14 2015, In : Glycobiology. 25, 10, p. 1079-1089 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Sterylglucoside catabolism in cryptococcus neoformans with endoglycoceramidase-related protein 2 (EGCrP2), the first steryl-β-glucosidase identified in fungi

Watanabe, T., Ito, T., Goda, H. M., Ishibashi, Y., Miyamoto, T., Ikeda, K., Taguchi, R., Okino, N. & Ito, M., Sep 9 2015, In : Journal of Biological Chemistry. 290, 2, p. 1005-1019 15 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2014

A novel ether-linked phytol-containing digalactosylglycerolipid in the marine green alga, Ulva pertusa

Ishibashi, Y., Nagamatsu, Y., Miyamoto, T., Matsunaga, N., Okino, N., Yamaguchi, K. & Ito, M., Oct 3 2014, In : Biochemical and Biophysical Research Communications. 452, 4, p. 873-880 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
20 Citations (Scopus)

Identification of perfluorooctane sulfonate binding protein in the plasma of tiger pufferfish Takifugu rubripes

Honda, M., Muta, A., Akasaka, T., Inoue, Y., Shimasaki, Y., Kannan, K., Okino, N. & Oshima, Y., Jun 2014, In : Ecotoxicology and Environmental Safety. 104, 1, p. 409-413 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Inhibition of GM3 synthase attenuates neuropathology of Niemann-Pick disease type C by affecting sphingolipid metabolism

Lee, H., Lee, J. K., Bae, Y. C., Yang, S. H., Okino, N., Schuchman, E. H., Yamashita, T., Bae, J. S. & Jin, H. K., Feb 2014, In : Molecules and cells. 37, 2, p. 161-171 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
17 Citations (Scopus)

Novel lysophospholipid acyltransferase PLAT1 of Aurantiochytrium limacinum F26-b responsible for generation of palmitate-docosahexaenoate- phosphatidylcholine and phosphatidylethanolamine

Abe, E., Ikeda, K., Nutahara, E., Hayashi, M., Yamashita, A., Taguchi, R., Doi, K., Honda, D., Okino, N. & Ito, M., Aug 4 2014, In : PloS one. 9, 8, e102377.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons

Lee, H., Lee, J. K., Park, M. H., Hong, Y. R., Marti, H. H., Kim, H., Okada, Y., Otsu, M., Seo, E. J., Park, J. H., Bae, J. H., Okino, N., He, X., Schuchman, E. H., Bae, J. S. & Jin, H. K., 2014, In : Nature communications. 5, 5514.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Pseudomonas-derived ceramidase induces production of inflammatory mediators from human keratinocytes via sphingosine-1-phosphate

Oizumi, A., Nakayama, H., Okino, N., Iwahara, C., Kina, K., Matsumoto, R., Ogawa, H., Takamori, K., Ito, M., Suga, Y. & Iwabuchi, K., Feb 25 2014, In : PloS one. 9, 2, e89402.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2013

Two Fatty Acid Elongases Possessing C18-Δ6/C18-Δ9/C20-Δ5 or C16-Δ9 Elongase Activity in Thraustochytrium sp. ATCC 26185

Ohara, J., Sakaguchi, K., Okita, Y., Okino, N. & Ito, M., Aug 1 2013, In : Marine Biotechnology. 15, 4, p. 476-486 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Vibrios adhere to epithelial cells in the intestinal tract of red sea bream, Pagrus major, utilizing GM4 as an attachment site

Chisada, S. I., Shimizu, K., Kamada, H., Matsunaga, N., Okino, N. & Ito, M., Apr 1 2013, In : FEMS microbiology letters. 341, 1, p. 18-26 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2012

Analysis of Δ12-fatty acid desaturase function revealed that two distinct pathways are active for the synthesis of PUFAs in T. aureum ATCC 34304

Matsuda, T., Sakaguchi, K., Hamaguchi, R., Kobayashi, T., Abe, E., Hama, Y., Hayashi, M., Honda, D., Okita, Y., Sugimoto, S., Okino, N. & Ito, M., Jun 1 2012, In : Journal of Lipid Research. 53, 6, p. 1210-1222 13 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Loss-of-function mutation in bi-functional marine bacterial sialyltransferase

Kajiwara, H., Katayama, S., Kakuta, Y., Okino, N., Ito, M., Mine, T. & Yamamoto, T., Oct 1 2012, In : Bioscience, Biotechnology and Biochemistry. 76, 9, p. 1639-1644 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Preparation and characterization of EGCase I, applicable to the comprehensive analysis of GSLs, using a rhodococcal expression system

Ishibashi, Y., Kobayashi, U., Hijikata, A., Sakaguchi, K., Goda, H. M., Tamura, T., Okino, N. & Ito, M., Oct 1 2012, In : Journal of Lipid Research. 53, 10, p. 2242-2251 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Quality control of fungus-specific glucosylceramide in Cryptococcus neoformans by endoglycoceramidase-related protein 1 (EGCrP1)

Ishibashi, Y., Ikeda, K., Sakaguchi, K., Okino, N., Taguchi, R. & Ito, M., Jan 2 2012, In : Journal of Biological Chemistry. 287, 1, p. 368-381 14 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Versatile transformation system that is applicable to both multiple transgene expression and gene targeting for thraustochytrids

Sakaguchi, K., Matsuda, T., Kobayashi, T., Ohara, J. I., Hamaguchi, R., Abe, E., Nagano, N., Hayashi, M., Ueda, M., Honda, D., Okita, Y., Taoka, Y., Sugimoto, S., Okino, N. & Ito, M., May 1 2012, In : Applied and environmental microbiology. 78, 9, p. 3193-3202 10 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2011

Glycosphingolipid receptors for pathogenic vibrios in intestines of mariculture fish

Matsunaga, N., Chisada, S. I., Fujioka, H., Takashima, K., Okino, N. & Ito, M., Jul 2011, In : Fisheries science. 77, 4, p. 583-590 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Increase of eicosapentaenoic acid in thraustochytrids through thraustochytrid ubiquitin promoter-driven expression of a fatty acid Δ5 desaturase gene

Kobayashi, T., Sakaguchi, K., Matsuda, T., Abe, E., Hama, Y., Hayashi, M., Honda, D., Okita, Y., Sugimoto, S., Okino, N. & Ito, M., Jun 1 2011, In : Applied and environmental microbiology. 77, 11, p. 3870-3876 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Lipid rafts enriched in monosialylGb5Cer carrying the stage-specific embryonic antigen-4 epitope are involved in development of mouse preimplantation embryos at cleavage stage

Sato, B., Katagiri, Y. U., Miyado, K., Okino, N., Ito, M., Akutsu, H., Okita, H., Umezawa, A., Fujimoto, J., Toshimori, K. & Kiyokawa, N., Apr 18 2011, In : BMC Developmental Biology. 11, 22.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Molecular cloning of a Pinguiochrysis pyriformis oleate-specific microsomal Δ12-fatty acid desaturase and functional analysis in yeasts and thraustochytrids

Matsuda, T., Sakaguchi, K., Kobayashi, T., Abe, E., Kurano, N., Sato, A., Okita, Y., Sugimoto, S., Hama, Y., Hayashi, M., Okino, N. & Ito, M., Oct 1 2011, In : Journal of biochemistry. 150, 4, p. 375-383 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Multiplex analysis of sphingolipids using amine-reactive tags (iTRAQ)

Nabetani, T., Makino, A., Hullin-Matsuda, F., Hirakawa, T. A., Takeoka, S., Okino, N., Ito, M., Kobayashi, T. & Hirabayashi, Y., Jun 1 2011, In : Journal of Lipid Research. 52, 6, p. 1294-1302 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Purification, molecular cloning, and application of a novel sphingomyelin-binding protein (clamlysin) from the brackishwater clam, Corbicula japonica

Takara, T., Nakagawa, T., Isobe, M., Okino, N., Ichinose, S., Omori, A. & Ito, M., May 1 2011, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1811, 5, p. 323-332 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)