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  • Nozomu Okino
2020

Determination of globotriaosylceramide analogs in the organs of a mouse model of Fabry disease

Ishii, S., Taguchi, A., Okino, N., Ito, M. & Maruyama, H., Apr 24 2020, In : Journal of Biological Chemistry. 295, 17, p. 5577-5587 11 p.

Research output: Contribution to journalArticle

Open Access
2019
Open Access

Expression, purification, and characterization of highly active endo-α-N-acetylgalactosaminidases expressed by silkworm-baculovirus expression system

Morio, A., Xu, J., Masuda, A., Kinoshita, Y., Hino, M., Morokuma, D., Goda, H. M., Okino, N., Ito, M., Mon, H., Fujita, R., Kusakabe, T. & Lee, J. M., Jun 2019, In : Journal of Asia-Pacific Entomology. 22, 2, p. 404-408 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The glycerol-3-phosphate acyltransferase PLAT2 functions in the generation of DHA-rich glycerolipids in Aurantiochytrium limacinum F26-b

Nutahara, E., Abe, E., Uno, S., Ishibashi, Y., Watanabe, T., Hayashi, M., Okino, N. & Ito, M., Jan 2019, In : PloS one. 14, 1, e0211164.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

Correction: Novel lysophospholipid acyltransferase plat1 of aurantiochytrium limacinum f26-b responsible for generation of palmitate-docosahexaenoate-phosphatidylcholine and phosphatidylethanolamine (PLoS ONE (2014) 9: 8 (e102377) DOI: 10.1371/journal.pone.0102377)

Abe, E., Ikeda, K., Nutahara, E., Hayashi, M., Yamashita, A., Taguchi, R., Doi, K., Honda, D., Okino, N. & Ito, M., Aug 2018, In : PloS one. 13, 8, e0203016.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice

Yoshihara, T., Satake, H., Nishie, T., Okino, N., Hatta, T., Otani, H., Naruse, C., Suzuki, H., Sugihara, K., Kamimura, E., Tokuda, N., Furukawa, K., Fururkawa, K., Ito, M. & Asano, M., Aug 2018, In : PLoS genetics. 14, 8, e1007545.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Molecular mechanism for Pseudomottas ceramidase expression through sphingosine-specific transcriptional regulator and its biological roles

Okino, N. & Ito, M., Jan 1 2018, In : Seikagaku. 90, 2, p. 178-182 5 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)
2017

Enhancing the sialylation of recombinant EPO produced in CHO cells via the inhibition of glycosphingolipid biosynthesis /631/1647/338/318 /631/61/318 /82/80 /82/83 article

Kwak, C. Y., Park, S. Y., Lee, C. G., Okino, N., Ito, M. & Kim, J. H., Dec 1 2017, In : Scientific reports. 7, 1, 13059.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Regulation of TG accumulation and lipid droplet morphology by the novel TLDP1 in Aurantiochytrium limacinum F26-b

Watanabe, T., Sakiyama, R., Iimi, Y., Sekine, S., Abe, E., Nomura, K. H., Nomura, K., Ishibashi, Y., Okino, N., Hayashi, M. & Ito, M., Jan 1 2017, In : Journal of Lipid Research. 58, 12, p. 2334-2347 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016
3 Citations (Scopus)
6 Citations (Scopus)
2015

Ergosteryl-β-glucosidase (Egh1) involved in sterylglucoside catabolism and vacuole formation in Saccharomyces cerevisiae

Watanabe, T., Tani, M., Ishibashi, Y., Endo, I., Okino, N. & Ito, M., Apr 14 2015, In : Glycobiology. 25, 10, p. 1079-1089 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Sterylglucoside catabolism in cryptococcus neoformans with endoglycoceramidase-related protein 2 (EGCrP2), the first steryl-β-glucosidase identified in fungi

Watanabe, T., Ito, T., Goda, H. M., Ishibashi, Y., Miyamoto, T., Ikeda, K., Taguchi, R., Okino, N. & Ito, M., Sep 9 2015, In : Journal of Biological Chemistry. 290, 2, p. 1005-1019 15 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2014

A novel ether-linked phytol-containing digalactosylglycerolipid in the marine green alga, Ulva pertusa

Ishibashi, Y., Nagamatsu, Y., Miyamoto, T., Matsunaga, N., Okino, N., Yamaguchi, K. & Ito, M., Oct 3 2014, In : Biochemical and Biophysical Research Communications. 452, 4, p. 873-880 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
20 Citations (Scopus)

Identification of perfluorooctane sulfonate binding protein in the plasma of tiger pufferfish Takifugu rubripes

Honda, M., Muta, A., Akasaka, T., Inoue, Y., Shimasaki, Y., Kannan, K., Okino, N. & Oshima, Y., Jun 2014, In : Ecotoxicology and Environmental Safety. 104, 1, p. 409-413 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Inhibition of GM3 synthase attenuates neuropathology of Niemann-Pick disease type C by affecting sphingolipid metabolism

Lee, H., Lee, J. K., Bae, Y. C., Yang, S. H., Okino, N., Schuchman, E. H., Yamashita, T., Bae, J. S. & Jin, H. K., Feb 2014, In : Molecules and cells. 37, 2, p. 161-171 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
17 Citations (Scopus)

Novel lysophospholipid acyltransferase PLAT1 of Aurantiochytrium limacinum F26-b responsible for generation of palmitate-docosahexaenoate- phosphatidylcholine and phosphatidylethanolamine

Abe, E., Ikeda, K., Nutahara, E., Hayashi, M., Yamashita, A., Taguchi, R., Doi, K., Honda, D., Okino, N. & Ito, M., Aug 4 2014, In : PloS one. 9, 8, e102377.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons

Lee, H., Lee, J. K., Park, M. H., Hong, Y. R., Marti, H. H., Kim, H., Okada, Y., Otsu, M., Seo, E. J., Park, J. H., Bae, J. H., Okino, N., He, X., Schuchman, E. H., Bae, J. S. & Jin, H. K., 2014, In : Nature communications. 5, 5514.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Pseudomonas-derived ceramidase induces production of inflammatory mediators from human keratinocytes via sphingosine-1-phosphate

Oizumi, A., Nakayama, H., Okino, N., Iwahara, C., Kina, K., Matsumoto, R., Ogawa, H., Takamori, K., Ito, M., Suga, Y. & Iwabuchi, K., Feb 25 2014, In : PloS one. 9, 2, e89402.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2013

Two Fatty Acid Elongases Possessing C18-Δ6/C18-Δ9/C20-Δ5 or C16-Δ9 Elongase Activity in Thraustochytrium sp. ATCC 26185

Ohara, J., Sakaguchi, K., Okita, Y., Okino, N. & Ito, M., Aug 1 2013, In : Marine Biotechnology. 15, 4, p. 476-486 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Vibrios adhere to epithelial cells in the intestinal tract of red sea bream, Pagrus major, utilizing GM4 as an attachment site

Chisada, S. I., Shimizu, K., Kamada, H., Matsunaga, N., Okino, N. & Ito, M., Apr 1 2013, In : FEMS microbiology letters. 341, 1, p. 18-26 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2011

Glycosphingolipid receptors for pathogenic vibrios in intestines of mariculture fish

Matsunaga, N., Chisada, S. I., Fujioka, H., Takashima, K., Okino, N. & Ito, M., Jul 2011, In : Fisheries science. 77, 4, p. 583-590 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Increase of eicosapentaenoic acid in thraustochytrids through thraustochytrid ubiquitin promoter-driven expression of a fatty acid Δ5 desaturase gene

Kobayashi, T., Sakaguchi, K., Matsuda, T., Abe, E., Hama, Y., Hayashi, M., Honda, D., Okita, Y., Sugimoto, S., Okino, N. & Ito, M., Jun 1 2011, In : Applied and environmental microbiology. 77, 11, p. 3870-3876 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Lipid rafts enriched in monosialylGb5Cer carrying the stage-specific embryonic antigen-4 epitope are involved in development of mouse preimplantation embryos at cleavage stage

Sato, B., Katagiri, Y. U., Miyado, K., Okino, N., Ito, M., Akutsu, H., Okita, H., Umezawa, A., Fujimoto, J., Toshimori, K. & Kiyokawa, N., Apr 18 2011, In : BMC Developmental Biology. 11, 22.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Molecular cloning of a Pinguiochrysis pyriformis oleate-specific microsomal Δ12-fatty acid desaturase and functional analysis in yeasts and thraustochytrids

Matsuda, T., Sakaguchi, K., Kobayashi, T., Abe, E., Kurano, N., Sato, A., Okita, Y., Sugimoto, S., Hama, Y., Hayashi, M., Okino, N. & Ito, M., Oct 1 2011, In : Journal of biochemistry. 150, 4, p. 375-383 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Multiplex analysis of sphingolipids using amine-reactive tags (iTRAQ)

Nabetani, T., Makino, A., Hullin-Matsuda, F., Hirakawa, T. A., Takeoka, S., Okino, N., Ito, M., Kobayashi, T. & Hirabayashi, Y., Jun 1 2011, In : Journal of Lipid Research. 52, 6, p. 1294-1302 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Purification, molecular cloning, and application of a novel sphingomyelin-binding protein (clamlysin) from the brackishwater clam, Corbicula japonica

Takara, T., Nakagawa, T., Isobe, M., Okino, N., Ichinose, S., Omori, A. & Ito, M., May 1 2011, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1811, 5, p. 323-332 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)