Find Research Outputs — Kyushu University

2019

Adult T-Cell Leukemia After Deceased Donor Liver Transplantation for Acute Liver Failure: A Case Report

Motomura, T., Yoshizumi, T., Kosai-Fujimoto, Y., Mano, Y., Toshima, T., Takeishi, K., Itoh, S., Harada, N., Ikegami, T., Soejima, Y., Yoshimoto, G., Akashi, K. & Mori, M., Jul 1 2019, In : Transplantation Proceedings. 51, 6, p. 1978-1981 4 p.

Research output: Contribution to journal › Article

Adult T Cell Leukemia Lymphoma

Acute Liver Failure

Deltaretrovirus

Liver Transplantation

Tissue Donors

Anti-GPRC5D/CD3 bispecific T-cell-redirecting antibody for the treatment of multiple myeloma

Kodama, T., Kochi, Y., Nakai, W., Mizuno, H., Baba, T., Habu, K., Sawada, N., Tsunoda, H., Shima, T., Miyawaki, K., Kikushige, Y., Mori, Y., Miyamoto, T., Maeda, T. & Akashi, K., Jan 1 2019, In : Molecular Cancer Therapeutics. 18, 9, p. 1555-1564 10 p.

Research output: Contribution to journal › Article

G-Protein-Coupled Receptors

Multiple Myeloma

T-Lymphocytes

Antibodies

Therapeutics

3 Citations (Scopus)

A phase II study of lenalidomide consolidation and maintenance therapy after autologous PBSCT in patients with multiple myeloma

on behalf of the Japan Study Group for Cell Therapy and Transplantation (JSCT), Jan 22 2019, In : International journal of hematology. 109, 1, p. 107-114 8 p.

Research output: Contribution to journal › Article

Multiple Myeloma

Peripheral Blood Stem Cell Transplantation

Dexamethasone

Therapeutics

lenalidomide

Atrial fibrillation observed in a patient with esophageal cancer treated with fluorouracil

Moriyama, S., Yokoyama, T., Irie, K., Ito, M., Tsuchihashi, K., Fukata, M., Kusaba, H., Maruyama, T. & Akashi, K., Nov 2019, In : Journal of Cardiology Cases. 20, 5, p. 183-186 4 p.

Research output: Contribution to journal › Article

Open Access

Esophageal Neoplasms

Fluorouracil

Atrial Fibrillation

Coronary Vessels

Nicorandil

Bortezomib-based strategy with autologous stem cell transplantation for newly diagnosed multiple myeloma: a phase II study by the Japan Study Group for Cell Therapy and Transplantation (JSCT-MM12)

Sunami, K., Matsumoto, M., Fuchida, S. I., Omoto, E., Takamatsu, H., Adachi, Y., Choi, I., Fujishima, N., Kiguchi, T., Miyamoto, T., Maeda, A., Suzumiya, J., Yamamura, R., Nagafuji, K., Nakazato, T., Kuroda, Y., Yujiri, T., Takamatsu, Y., Harada, M. & Akashi, K., Jan 1 2019, In : International Journal of Clinical Oncology.

Research output: Contribution to journal › Article

Cell Transplantation

Stem Cell Transplantation

Group Psychotherapy

Cell- and Tissue-Based Therapy

Multiple Myeloma

CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines

Takaki-Kuwahara, A., Arinobu, Y., Miyawaki, K., Yamada, H., Tsuzuki, H., Irino, K., Ayano, M., Kimoto, Y., Mitoma, H., Akahoshi, M., Tsukamoto, H., Horiuchi, T., Niiro, H. & Akashi, K., Aug 30 2019, In : Arthritis Research and Therapy. 21, 1, 198.

Research output: Contribution to journal › Article

Open Access

Rheumatoid Arthritis

Joints

Lymphocytes

Cytokines

Synovial Fluid

CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: A post hoc analysis of a phase I/II clinical trial conducted in Japan

Ayano, M., Tsukamoto, H., Mitoma, H., Kimoto, Y., Akahoshi, M., Arinobu, Y., Miyamoto, T., Horiuchi, T., Niiro, H., Nagafuji, K., Harada, M. & Akashi, K., Jan 22 2019, In : Arthritis Research and Therapy. 21, 1, 30.

Research output: Contribution to journal › Article

Phase II Clinical Trials

Clinical Trials, Phase I

Systemic Scleroderma

Hematopoietic Stem Cell Transplantation

Japan

Cessation of nilotinib in patients with chronic myelogenous leukemia who have maintained deep molecular responses for 2 years: a multicenter phase 2 trial, stop nilotinib (NILSt)

Nagafuji, K., Matsumura, I., Shimose, T., Kawaguchi, T., Kuroda, J., Nakamae, H., Miyamoto, T., Kadowaki, N., Ishikawa, J., Imamura, Y., Yamazaki, H., Akashi, K. & Kanakura, Y., Dec 1 2019, In : International journal of hematology. 110, 6, p. 675-682 8 p.

Research output: Contribution to journal › Article

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Leukemia, Myeloid, Chronic Phase

Therapeutics

4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide

Recurrence

Clinicopathological features of HCV-positive splenic diffuse large B cell lymphoma

Shimono, J., Miyoshi, H., Arakawa, F., Yamada, K., Sugio, T., Miyawaki, K., Eto, T., Miyagishima, T., Kato, K., Nagafuji, K., Akashi, K., Teshima, T. & Ohshima, K., May 1 2019, In : Annals of Hematology. 98, 5, p. 1197-1207 11 p.

Research output: Contribution to journal › Article

Lymphoma, Large B-Cell, Diffuse

Hepacivirus

B-Cell Lymphoma

RNA

Reverse Transcription

Comparison of calcineurin inhibitors in combination with conventional methotrexate, reduced methotrexate, or mycophenolate mofetil for prophylaxis of graft-versus-host disease after umbilical cord blood transplantation

Yoshida, S., Ohno, Y., Nagafuji, K., Yoshimoto, G., Sugio, T., Kamimura, T., Ohta, T., Takase, K., Henzan, H., Muta, T., Iwasaki, H., Ogawa, R., Eto, T., Akashi, K. & Miyamoto, T., Nov 1 2019, In : Annals of Hematology. 98, 11, p. 2579-2591 13 p.

Research output: Contribution to journal › Article

Mycophenolic Acid

Graft vs Host Disease

Fetal Blood

Methotrexate

Transplantation

Correction to: A phase II study of lenalidomide consolidation and maintenance therapy after autologous PBSCT in patients with multiple myeloma (International Journal of Hematology, (2019), 109, 1, (107-114), 10.1007/s12185-018-2543-y)

on behalf of the Japan Study Group for Cell Therapy and Transplantation (JSCT), Jan 22 2019, In : International journal of hematology. 109, 1, 1 p.

Research output: Contribution to journal › Comment/debate

Hematology

Multiple Myeloma

Fees and Charges

Pharmaceutical Preparations

Organized Financing

10 Citations (Scopus)

Dedifferentiation process driven by TGF-beta signaling enhances stem cell properties in human colorectal cancer

Nakano, M., Kikushige, Y., Miyawaki, K., Kunisaki, Y., Mizuno, S., Takenaka, K., Tamura, S., Okumura, Y., Ito, M., Ariyama, H., Kusaba, H., Nakamura, M., Maeda, T., Baba, E. & Akashi, K., Feb 7 2019, In : Oncogene. 38, 6, p. 780-793 14 p.

Research output: Contribution to journal › Article

Neoplastic Stem Cells

Transforming Growth Factor beta

Colorectal Neoplasms

Stem Cells

Organoids

Efficacy and safety of ramucirumab plus modified FOLFIRI for metastatic colorectal cancer

Yoshihiro, T., Kusaba, H., Makiyama, A., Kobayashi, K., Uenomachi, M., Ito, M., Doi, Y., Mitsugi, K., Aikawa, T., Takayoshi, K., Esaki, T., Shimokawa, H., Tsuchihashi, K., Ariyama, H., Akashi, K. & Baba, E., May 15 2019, In : International Journal of Clinical Oncology. 24, 5, p. 508-515 8 p.

Research output: Contribution to journal › Article

Colorectal Neoplasms

Safety

irinotecan

Confidence Intervals

ramucirumab

Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia

Elbadry, M. I., Mizumaki, H., Hosokawa, K., Espinoza, J. L., Nakagawa, N., Yoshida, Y., Katagiri, T., Hosomichi, K., Zaimoku, Y., Imi, T., Nguyen, M. A. T., Fujii, Y., Tajima, A., Ogawa, S., Takenaka, K., Akashi, K. & Nakao, S., Jan 1 2019, In : Haematologica. 104, 10, p. E447-E450

Research output: Contribution to journal › Letter

Open Access

Aplastic Anemia

Hematopoiesis

Hematopoietic Stem Cells

Evaluation of the compliance with antiemetic guidelines for prevention of chemotherapy-induced nausea and vomiting in patients with hematologic malignancy

Uchida, M., Nakamura, T., Shima, T., Mori, Y., Yoshimoto, G., Kato, K., Shimokawa, M., Hosohata, K., Miyamoto, T. & Akashi, K., Jan 1 2019, In : Pharmazie. 74, 4, p. 250-254 5 p.

Research output: Contribution to journal › Article

Antiemetics

Hematologic Neoplasms

Nausea

Vomiting

Guidelines

Glucose signaling in the brain and periphery to memory

Hossain, M. S., Oomura, Y., Fujino, T. & Akashi, K., Jan 1 2019, In : Neuroscience and Biobehavioral Reviews.

Research output: Contribution to journal › Review article

Glucose

Brain

Vagus Nerve Stimulation

Incretins

Gene Expression

1 Citation (Scopus)

Hypoalbuminemia for the prediction of venous thromboembolism and treatment of direct oral anticoagulants in metastatic gastric cancer patients

Takayoshi, K., Kusaba, H., Aikawa, T., Koreishi, S., Sagara, K., Nakano, M., Komoda, M., Kono, M., Fukata, M., Arita, T., Esaki, T., Akashi, K. & Baba, E., Sep 5 2019, In : Gastric Cancer. 22, 5, p. 988-998 11 p.

Research output: Contribution to journal › Article

Hypoalbuminemia

Venous Thromboembolism

Anticoagulants

Stomach Neoplasms

Therapeutics

Impact of CYP3A5, POR, and CYP2C19 Polymorphisms on Trough Concentration to Dose Ratio of Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplantation

Suetsugu, K., Mori, Y., Yamamoto, N., Shigematsu, T., Miyamoto, T., Egashira, N., Akashi, K. & Masuda, S., May 15 2019, In : International journal of molecular sciences. 20, 10

Research output: Contribution to journal › Article

Open Access

Cytochrome P-450 CYP3A

transplantation

stem cells

Hematopoietic Stem Cell Transplantation

polymorphism

Large-scale genome analysis of bovine commensal Escherichia coli reveals that bovine-adapted E. Coli lineages are serving as evolutionary sources of the emergence of human intestinal pathogenic strains

Arimizu, Y., Kirino, Y., Sato, M. P., Uno, K., Sato, T., Gotoh, Y., Auvray, F., Brugere, H., Oswald, E., Mainil, J. G., Anklam, K. S., Döpfer, D., Yoshino, S., Ooka, T., Tanizawa, Y., Nakamura, Y., Iguchi, A., Morita-Ishihara, T., Ohnishi, M., Akashi, K. & 2 others, Hayashi, T. & Ogura, Y., Jan 1 2019, In : Genome Research. 29, 9, p. 1495-1505 11 p.

Research output: Contribution to journal › Article

Open Access

Enteropathogenic Escherichia coli

Genome

Escherichia coli

Virulence

Enterocytes

5 Citations (Scopus)

Myeloablative and reduced-intensity conditioning in HLA-haploidentical peripheral blood stem cell transplantation using post-transplant cyclophosphamide

on behalf of the Japan Study Group for Cell Therapy and Transplantation (JSCT), Mar 1 2019, In : Bone Marrow Transplantation. 54, 3, p. 432-441 10 p.

Research output: Contribution to journal › Article

Peripheral Blood Stem Cell Transplantation

Graft vs Host Disease

Cyclophosphamide

Disease-Free Survival

Transplants

21 Citations (Scopus)

Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial

TOURMALINE-MM3 study group, Jan 19 2019, In : The Lancet. 393, 10168, p. 253-264 12 p.

Research output: Contribution to journal › Article

Stem Cell Transplantation

Placebos

Maintenance

Multiple Myeloma

Disease-Free Survival

1 Citation (Scopus)

Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells

Ali, F., Hossain, M. S., Sejimo, S. & Akashi, K., May 1 2019, In : Molecular Neurobiology. 56, 5, p. 3404-3419 16 p.

Research output: Contribution to journal › Article

Plasmalogens

Toll-Like Receptor 4

Endocytosis

Alzheimer Disease

Caspases

1 Citation (Scopus)

Previous exposure to bortezomib is linked to a lower risk of engraftment syndrome after autologous hematopoietic stem cell transplantation

Mori, Y., Yoshimoto, G., Yuda, J. I., Hayashi, M., Odawara, J., Kuriyama, T., Sugio, T., Miyawaki, K., Kamezaki, K., Kato, K., Takenaka, K., Iwasaki, H., Maeda, T., Miyamoto, T. & Akashi, K., Jan 2 2019, In : Leukemia and Lymphoma. 60, 1, p. 271-273 3 p.

Research output: Contribution to journal › Letter

Hematopoietic Stem Cell Transplantation

Bortezomib

Prospective evaluation of minimal residual disease monitoring to predict prognosis of adult patients with Ph-negative acute lymphoblastic leukemia

Nagafuji, K., Miyamoto, T., Eto, T., Ogawa, R., Okumura, H., Takase, K., Kawano, N., Miyazaki, Y., Fujisaki, T., Wake, A., Ohno, Y., Kurokawa, T., Kamimura, T., Takamatsu, Y., Yokota, S. & Akashi, K., Jan 1 2019, In : European Journal of Haematology. 103, 3, p. 164-171 8 p.

Research output: Contribution to journal › Article

Residual Neoplasm

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Disease-Free Survival

Hematopoietic Stem Cell Transplantation

Consolidation Chemotherapy

1 Citation (Scopus)

PUFA-Plasmalogens Attenuate the LPS-Induced Nitric Oxide Production by Inhibiting the NF-kB, p38 MAPK and JNK Pathways in Microglial Cells

Youssef, M., Ibrahim, A., Akashi, K. & Hossain, M. S., Jan 15 2019, In : Neuroscience. 397, p. 18-30 13 p.

Research output: Contribution to journal › Article

Plasmalogens

MAP Kinase Signaling System

p38 Mitogen-Activated Protein Kinases

Lipopolysaccharides

Nitric Oxide

2 Citations (Scopus)

Recovery from left ventricular dysfunction was associated with the early introduction of heart failure medical treatment in cancer patients with anthracycline-induced cardiotoxicity

Ohtani, K., Fujino, T., Ide, T., Funakoshi, K., Sakamoto, I., Hiasa, K. I., Higo, T., Kamezaki, K., Akashi, K. & Tsutsui, H., Jun 1 2019, In : Clinical Research in Cardiology. 108, 6, p. 600-611 12 p.

Research output: Contribution to journal › Article

Anthracyclines

Left Ventricular Dysfunction

Heart Failure

Treatment Failure

Neoplasms

Risk of secondary primary malignancies in multiple myeloma patients with or without autologous stem cell transplantation

For the Fukuoka Blood and Marrow Transplantation Group, Jan 22 2019, In : International journal of hematology. 109, 1, p. 98-106 9 p.

Research output: Contribution to journal › Article

Stem Cell Transplantation

Multiple Myeloma

Transplants

Neoplasms

Thalidomide

1 Citation (Scopus)

Safety and Seropositivity after Live Attenuated Vaccine in Adult Patients Receiving Hematopoietic Stem Cell Transplantation

Aoki, T., Kamimura, T., Yoshida, S., Mori, Y., Kadowaki, M., Kohno, K., Ishihara, D., Urata, S., Sugio, T., Kamezaki, K., Kato, K., Ito, Y., Eto, T., Akashi, K. & Miyamoto, T., Aug 2019, In : Biology of Blood and Marrow Transplantation. 25, 8, p. 1576-1585 10 p.

Research output: Contribution to journal › Article

Attenuated Vaccines

Hematopoietic Stem Cell Transplantation

Measles

Safety

Mumps

1 Citation (Scopus)

Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells

Tominaga, K., Minato, H., Murayama, T., Sasahara, A., Nishimura, T., Kiyokawa, E., Kanauchi, H., Shimizu, S., Sato, A., Nishioka, K., Tsuji, E. I., Yano, M., Ogawa, T., Ishii, H., Mori, M., Akashi, K., Okamoto, K., Tanabe, M., Tada, K. I., Tojo, A. & 1 others, Gotoh, N., Jan 8 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 2, p. 625-630 6 p.

Research output: Contribution to journal › Article

Semaphorins

Neoplastic Stem Cells

Cell Division

Neuropilin-1

Breast Neoplasms

Serum levels of fibroblast growth factor-2 distinguish Takayasu arteritis from giant cell arteritis independent of age at diagnosis

Fukui, S., Kuwahara-Takaki, A., Ono, N., Sato, S., Koga, T., Kawashiri, S. Y., Iwanaga, N., Iwamoto, N., Ichinose, K., Tamai, M., Nakamura, H., Origuchi, T., Migita, K., Arinobu, Y., Niiro, H., Tada, Y., Akashi, K., Maeda, T. & Kawakami, A., Dec 1 2019, In : Scientific reports. 9, 1, 688.

Research output: Contribution to journal › Article

Takayasu Arteritis

Giant Cell Arteritis

Fibroblast Growth Factor 2

Granulocyte-Macrophage Colony-Stimulating Factor

Serum

Sick sinus syndrome observed in a patient with cholinesterase deficiency

Yasuda, S., Fukata, M., Yokoyama, T., Arita, T., Odashiro, K., Maruyama, T., Hiramoto, Y. & Akashi, K., Jan 1 2019, In : Internal Medicine. 58, 6, p. 809-812 4 p.

Research output: Contribution to journal › Article

Open Access

Sick Sinus Syndrome

Cholinesterases

Atrial Fibrillation

Sinoatrial Node

Bradycardia

Successful rescue transplantation with desensitization procedure after primary graft failure due to donor-specific antibody

Minami, M., Matsushima, T., Mori, Y., Ishihara, D., Jinnnouchi, F., Takenaka, K., Tomoko, H., Yoshimoto, G., Numata, A., Kato, K., Maeda, T., Miyamoto, T. & Akashi, K., Aug 1 2019, In : Bone Marrow Transplantation. 54, 8, p. 1374-1376 3 p.

Research output: Contribution to journal › Letter

Transplantation

Transplants

Antibodies

2018

9 Citations (Scopus)

Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody

Yamaguchi, K., Mishima, K., Ohmura, H., Hanamura, F., Ito, M., Nakano, M., Tsuchihashi, K., Ota, S. I., Wada, N., Uchi, H., Ariyama, H., Kusaba, H., Niiro, H., Akashi, K. & Baba, E., Oct 2018, In : Cancer Science. 109, 10, p. 3032-3042 11 p.

Research output: Contribution to journal › Article

Th1 Cells

Melanoma

T-Lymphocytes

Antibodies

Phenotype

Analysis of GNA13 Protein in Follicular Lymphoma and its Association with Poor Prognosis

Shimono, J., Miyoshi, H., Yoshida, N., Kato, T., Sato, K., Sugio, T., Miyawaki, K., Kurita, D., Sasaki, Y., Kawamoto, K., Imaizumi, Y., Kato, K., Nagafuji, K., Akashi, K., Seto, M., Teshima, T. & Ohshima, K., Nov 1 2018, In : American Journal of Surgical Pathology. 42, 11, p. 1466-1471 6 p.

Research output: Contribution to journal › Article

Follicular Lymphoma

Disease Progression

Disease-Free Survival

Proteins

GTP-Binding Proteins

A phase 2 study of fosaprepitant combined with high-dose dexamethasone for Japanese cancer patients receiving highly emetogenic chemotherapy

Kumagai, H., Kusaba, H., Yamanaka, T., Nio, K., Inadomi, K., Takayoshi, K., Ito, M., Tamura, S., Makiyama, A., Makiyama, C., Hirano, G., Shibata, Y., Shirakawa, T., Mitsugi, K., Ariyama, H., Esaki, T., Akashi, K. & Baba, E., Jun 1 2018, In : Medicine (United States). 97, 25, e11042.

Research output: Contribution to journal › Article

fosaprepitant

Dexamethasone

Antiemetics

Drug Therapy

Neoplasms

1 Citation (Scopus)

Association of atrial fibrillation and gastroesophageal reflux disease: Natural and therapeutic linkage of the two common diseases

Maruyama, T., Fukata, M. & Akashi, K., Jan 1 2018, (Accepted/In press) In : journal of arrhythmia.

Research output: Contribution to journal › Article

Gastroesophageal Reflux

Atrial Fibrillation

Therapeutics

Proton Pump Inhibitors

Inflammation

Comparative quantification of chemotherapy-induced nausea and emesis between the common terminology criteria for adverse events and the multinational association of supportive care in cancer antiemesis tool

Uchida, M., Nakamura, T., Shima, T., Yoshimoto, G., Kato, K., Hosohata, K., Miyamoto, T. & Akashi, K., Jan 1 2018, In : Biological and Pharmaceutical Bulletin. 41, 11, p. 1667-1671 5 p.

Research output: Contribution to journal › Article

Terminology

Nausea

Vomiting

Drug Therapy

Neoplasms

1 Citation (Scopus)

Comparison of antiemetic effects of granisetron and palonosetron in patients receiving bendamustine-based chemotherapy

Uchida, M., Nakamura, T., Makihara, Y., Suetsugu, K., Ikesue, H., Mori, Y., Kato, K., Shiratsuchi, M., Hosohata, K., Miyamoto, T. & Akashi, K., Jan 1 2018, In : Pharmazie. 73, 5, p. 304-308 5 p.

Research output: Contribution to journal › Article

Granisetron

Antiemetics

Drug Therapy

Nausea

Vomiting

Cyclophosphamide-induced tolerance in kidney transplantation avoids long-term immunosuppressive therapy

Takeuchi, A., Kato, K., Akashi, K. & Eto, M., Feb 1 2018, In : International Journal of Urology. 25, 2, p. 112-120 9 p.

Research output: Contribution to journal › Review article

Immunosuppressive Agents

Kidney Transplantation

Cyclophosphamide

Chimerism

Transplantation

6 Citations (Scopus)

Development of a 2-h suicide prevention program for medical staff including nurses and medical residents: A two-center pilot trial

Nakagami, Y., Kubo, H., Katsuki, R., Sakai, T., Sugihara, G., Naito, C., Oda, H., Hayakawa, K., Suzuki, Y., Fujisawa, D., Hashimoto, N., Kobara, K., Cho, T., Kuga, H., Takao, K., Kawahara, Y., Matsumura, Y., Murai, T., Akashi, K., Kanba, S. & 2 others, Otsuka, K. & Kato, T. A., Jan 1 2018, In : Journal of Affective Disorders. 225, p. 569-576 8 p.

Research output: Contribution to journal › Article

Medical Staff

Suicide

Nurses

Depression

First Aid

17 Citations (Scopus)

Dual inhibition of EZH1/2 breaks the quiescence of leukemia stem cells in acute myeloid leukemia

Fujita, S., Honma, D., Adachi, N., Araki, K., Takamatsu, E., Katsumoto, T., Yamagata, K., Akashi, K., Aoyama, K., Iwama, A. & Kitabayashi, I., Apr 1 2018, In : Leukemia. 32, 4, p. 855-864 10 p.

Research output: Contribution to journal › Article

Acute Myeloid Leukemia

Leukemia

Stem Cells

Polycomb Repressive Complex 2

Cyclin D

2 Citations (Scopus)

E-cadherin regulates proliferation of colorectal cancer stem cells through NANOG

Tamura, S., Isobe, T., Ariyama, H., Nakano, M., Kikushige, Y., Takaishi, S., Kusaba, H., Takenaka, K., Ueki, T., Nakamura, M., Akashi, K. & Baba, E., Aug 2018, In : Oncology reports. 40, 2, p. 693-703 11 p.

Research output: Contribution to journal › Article

Neoplastic Stem Cells

Cadherins

Colorectal Neoplasms

Cyclin D1

Embryonic Stem Cells

1 Citation (Scopus)

Effect of ruxolitinib therapy on the quality-of-life of Japanese patients with myelofibrosis

Oritani, K., Ohishi, K., Okamoto, S., Kirito, K., Komatsu, N., Tauchi, T., Handa, H., Saito, S., Takenaka, K., Shimoda, K., Okada, H., Amagasaki, T., Wakase, S., Shimozuma, K. & Akashi, K., Jan 4 2018, In : Current Medical Research and Opinion. 34, 3, p. 531-537 7 p.

Research output: Contribution to journal › Article

Primary Myelofibrosis

Quality of Life

Therapeutics

Janus Kinase 1

Spleen

5 Citations (Scopus)

Effects of tumor necrosis factor inhibitors and tocilizumab on the glycosylated hemoglobin levels in patients with rheumatoid arthritis; an observational study

Otsuka, Y., Kiyohara, C., Kashiwado, Y., Sawabe, T., Nagano, S., Kimoto, Y., Ayano, M., Mitoma, H., Akahoshi, M., Arinobu, Y., Niiro, H., Akashi, K. & Horiuchi, T., Apr 2018, In : PloS one. 13, 4, e0196368.

Research output: Contribution to journal › Article

glycohemoglobin

rheumatoid arthritis

tumor necrosis factors

Glycosylated Hemoglobin A

observational studies

1 Citation (Scopus)

Efficacy and safety of switching to nilotinib in patients with CML-CP in major molecular response to imatinib: results of a multicenter phase II trial (NILSw trial)

Ishikawa, J., Matsumura, I., Kawaguchi, T., Kuroda, J., Nakamae, H., Miyamoto, T., Matsuoka, K. I., Shibayama, H., Hino, M., Hirase, C., Kamimura, T., Shimose, T., Akashi, K. & Kanakura, Y., May 1 2018, In : International journal of hematology. 107, 5, p. 535-540 6 p.

Research output: Contribution to journal › Article

Safety

4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide

Imatinib Mesylate

Dyspnea

Atrial Fibrillation

1 Citation (Scopus)

Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate–sensitive glutamate receptor signaling

Suina, K., Tsuchihashi, K., Yamasaki, J., Kamenori, S., Shintani, S., Hirata, Y., Okazaki, S., Sampetrean, O., Baba, E., Akashi, K., Mitsuishi, Y., Takahashi, F., Takahashi, K., Saya, H. & Nagano, O., Dec 2018, In : Cancer Science. 109, 12, p. 3874-3882 9 p.

Research output: Contribution to journal › Article

Glutamate Receptors

Epidermal Growth Factor Receptor

Glioma

Glutamic Acid

Epidermal Growth Factor

Epithelial-mesenchymal transition is activated in CD44-positive malignant ascites tumor cells of gastrointestinal cancer

Nakano, M., Ito, M., Tanaka, R., Ariyama, H., Mitsugi, K., Makiyama, A., Uchino, K., Esaki, T., Tsuruta, N., Hanamura, F., Yamaguchi, K., Okumura, Y., Sagara, K., Takayoshi, K., Nio, K., Tsuchihashi, K., Tamura, S., Shimokawa, H., Arita, S., Miyawaki, K. & 3 others, Kusaba, H., Akashi, K. & Baba, E., Nov 2018, In : Cancer Science. 109, 11, p. 3461-3470 10 p.

Research output: Contribution to journal › Article

Gastrointestinal Neoplasms

Epithelial-Mesenchymal Transition

Ascites

Neoplasms

Transforming Growth Factor beta

Erratum: Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack (Blood Adv) (2018) 2:4 (390-400) DOI: 10.1182/bloodadvances.201701334)

Espinoza, J. L., Elbadry, M. I., Chonabayashi, K., Yoshida, Y., Katagiri, T., Harada, K., Nakagawa, N., Zaimoku, Y., Imi, T., Takamatsu, H., Ozawa, T., Maruyama, H., Hassanein, H. A., Noreldin, A. K. A., Takenaka, K., Akashi, K., Hamana, H., Kishi, H., Akatsuka, Y. & Nakao, S., Sep 11 2018, In : Blood Advances. 2, 17, 1 p.

Research output: Contribution to journal › Comment/debate

Manuscripts

Aplastic Anemia

Hematopoiesis

Hematopoietic Stem Cells

Authorship

1 Citation (Scopus)

Evaluation of the dose and efficacy of ruxolitinib in Japanese patients with myelofibrosis

Kirito, K., Okamoto, S., Ohishi, K., Tauchi, T., Handa, H., Saito, S., Takenaka, K., Shimoda, K., Oritani, K., Akashi, K., Okada, H., Amagasaki, T., Suzuki, K., Yonezu, T. & Komatsu, N., Jan 1 2018, In : International journal of hematology. 107, 1, p. 92-97 6 p.

Research output: Contribution to journal › Article

Primary Myelofibrosis

Spleen

Splenomegaly

Therapeutics

INCB018424

3 Citations (Scopus)

Expansion of NKG2C-expressing natural killer cells after umbilical cord blood transplantation in a patient with peripheral T-cell lymphoma with cytotoxic molecules

Muta, T., Yoshihiro, T., Jinnouchi, F., Aoki, K., Kochi, Y., Shima, T., Takenaka, K., Ogawa, R., Akashi, K. & Oshima, K., Jan 1 2018, In : Internal Medicine. 57, 6, p. 861-866 6 p.

Research output: Contribution to journal › Article

Peripheral T-Cell Lymphoma

Fetal Blood

Natural Killer Cells

Transplantation

Tissue Donors