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  • Hiroyuki Tsutsui
2020

Association of short-term exposure to air pollution with myocardial infarction with and without obstructive coronary artery disease

on the behalf of the JROAD Investigators, Jan 1 2020, (Accepted/In press) In : European Journal of Preventive Cardiology.

Research output: Contribution to journalArticle

Brain perivascular macrophages contribute to the development of hypertension in stroke-prone spontaneously hypertensive rats via sympathetic activation

Iyonaga, T., Shinohara, K., Mastuura, T., Hirooka, Y. & Tsutsui, H., Feb 1 2020, In : Hypertension Research. 43, 2, p. 99-110 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
1 Citation (Scopus)

Erratum: Baseline demographics and clinical characteristics in the All Nippon AF in the Elderly (ANAFIE) registry (Circulation Journal (2019) 83 (1538-1545) DOI: 10.1253/circj.CJ-19-0094)

Koretsune, Y., Yamashita, T., Akao, M., Atarashi, H., Ikeda, T., Okumura, K., Shimizu, W., Tsutsui, H., Toyoda, K., Hirayama, A., Yasaka, M., Yamaguchi, T., Teramukai, S., Kimura, T., Kaburagi, J., Takita, A. & Inoue, H., Jan 1 2020, In : Circulation Journal. 84, 2, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Impact of population density on mortality in patients hospitalized for heart failure – JROAD-DPC Registry Analysis –

Konishi, M., Matsuzawa, Y., Ebina, T., Kosuge, M., Gohbara, M., Nishimura, K., Nakai, M., Miyamoto, Y., Saito, Y., Tsutsui, H., Komuro, I., Ogawa, H., Tamura, K. & Kimura, K., Apr 2020, In : Journal of Cardiology. 75, 4, p. 447-453 7 p.

Research output: Contribution to journalArticle

Left ventricular noncompaction with multiple thrombi in apical aneurysm

Yakabe, D., Matsushima, S., Uchino, S., Ohtani, K., Ide, T., Higo, T. & Tsutsui, H., Feb 1 2020, In : Internal Medicine. 59, 3, p. 377-381 5 p.

Research output: Contribution to journalArticle

Open Access

Rhythm versus rate control strategies regarding anticoagulant use in elderly non-valvular atrial fibrillation patients: Subanalysis of the ANAFIE (All Nippon AF In the Elderly) Registry

Yuzawa, H., Inoue, H., Yamashita, T., Akao, M., Atarashi, H., Koretsune, Y., Okumura, K., Shimizu, W., Tsutsui, H., Toyoda, K., Hirayama, A., Yasaka, M., Yamaguchi, T., Teramukai, S., Kimura, T., Kaburagi, J., Takita, A. & Ikeda, T., Jan 1 2020, (Accepted/In press) In : Journal of Cardiology.

Research output: Contribution to journalArticle

Short-term exposure to desert dust and the risk of acute myocardial infarction in Japan: a time-stratified case-crossover study

JROAD Investigators, Jan 1 2020, (Accepted/In press) In : European Journal of Epidemiology.

Research output: Contribution to journalArticle

Spironolactone use is associated with improved outcomes in heart failure with mid-range ejection fraction

Enzan, N., Matsushima, S., Ide, T., Kaku, H., Higo, T., Tsuchihashi-Makaya, M. & Tsutsui, H., Jan 1 2020, (Accepted/In press) In : ESC Heart Failure.

Research output: Contribution to journalArticle

Open Access

The disruption of invariant natural killer T cells exacerbates cardiac hypertrophy and failure caused by pressure overload in mice

Takahashi, M., Kinugawa, S., Takada, S., Kakutani, N., Furihata, T., Sobirin, M. A., Fukushima, A., Obata, Y., Saito, A., Ishimori, N., Iwabuchi, K. & Tsutsui, H., Jan 1 2020, (Accepted/In press) In : Experimental Physiology.

Research output: Contribution to journalArticle

2019
Open Access
2 Citations (Scopus)

Architecture of the Japan ischemic heart disease multimodal prospective data acquisition for precision treatment (J-IMPACT) system

Matoba, T., Kohro, T., Fujita, H., Nakayama, M., Kiyosue, A., Miyamoto, Y., Nishimura, K., Hashimoto, H., Antoku, Y., Nakashima, N., Ohe, K., Ogawa, H., Tsutsui, H. & Nagai, R., Jan 1 2019, In : International heart journal. 60, 2, p. 264-270 7 p.

Research output: Contribution to journalArticle

Open Access

Assessment of coronary flow velocity reserve in the left main trunk using phase-contrast MR imaging at 3T: Comparison with 15O-labeled water positron emission tomography

Kikuchi, Y., Naya, M., Manabe, N. O., Manabe, O., Sugimori, H., Kudo, K., Kato, F., Aikawa, T., Tsutsui, H., Tamaki, N. & Shirato, H., Jan 1 2019, In : Magnetic Resonance in Medical Sciences. 18, 2, p. 134-141 8 p.

Research output: Contribution to journalArticle

Open Access

Association between prehospital supraglottic airway compared with bag-mask ventilation and Glasgow–Pittsburgh cerebral performance category 1 in patients with out-of-hospital cardiac arrest

Jinno, K., Hifumi, T., Okazaki, T., Kuroda, Y., Tahara, Y., Yonemoto, N., Nonogi, H., Nagao, K., Ikeda, T., Sato, N. & Tsutsui, H., Jan 1 2019, In : Circulation Journal. 83, 12, p. 2479-2486 8 p.

Research output: Contribution to journalArticle

Open Access

A statement on the appropriate administration of tafamidis in patients with transthyretin cardiac amyloidosis

Endo, J., Sano, M., Izumiya, Y., Tsujita, K., Nakamura, K., Tahara, N., Kuwahara, K., Inomata, T., Ueda, M., Sekijima, Y., Ando, Y., Tsutsui, H., Isobe, M. & Fukuda, K., Jan 1 2019, In : Circulation Journal. 84, 1, p. 15-17 3 p.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Baseline demographics and clinical characteristics in the all nippon af in the elderly (ANAFIE) registry

Koretsune, Y., Yamashita, T., Akao, M., Atarashi, H., Ikeda, T., Okumura, K., Shimizu, W., Tsutsui, H., Toyoda, K., Hirayama, A., Yasaka, M., Yamaguchi, T., Teramukai, S., Kimura, T., Kaburagi, J., Takita, A. & Inoue, H., Jan 1 2019, In : Circulation Journal. 83, 7, p. 1538-1545 8 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Blockade of L-type Ca2+ channel attenuates doxorubicin-induced cardiomyopathy via suppression of CaMKII-NF-κB pathway

Ikeda, S., Matsushima, S., Okabe, K., Ikeda, M., Ishikita, A., Tadokoro, T., Enzan, N., Yamamoto, T., Sada, M., Deguchi, H., Morimoto, S., Ide, T. & Tsutsui, H., Dec 1 2019, In : Scientific reports. 9, 1, 9850.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Cardioprotective effect of renin–angiotensin inhibitors and β-blockers in trastuzumab-related cardiotoxicity

Ohtani, K., Ide, T., Hiasa, K. I., Sakamoto, I., Yamashita, N., Kubo, M. & Tsutsui, H., Oct 1 2019, In : Clinical Research in Cardiology. 108, 10, p. 1128-1139 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Cilostazol is useful for the treatment of sinus bradycardia and associated hemodynamic deterioration following heart transplantation

Uchikawa, T., Fujino, T., Higo, T., Ohtani, K., Shiose, A. & Tsutsui, H., Jan 1 2019, In : International heart journal. 60, 5, p. 1222-1225 4 p.

Research output: Contribution to journalArticle

Open Access

Diabetes mellitus attenuates the pressure response against hypotensive stress by impairing the sympathetic regulation of the baroreflex afferent arc

Kamada, K., Saku, K., Tohyama, T., Kawada, T., Mannoji, H., Abe, K., Nishikawa, T., Sunagawa, G., Kishi, T., Sunagawa, K. & Tsutsui, H., Jan 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 1, p. H35-H44

Research output: Contribution to journalArticle

Early therapeutic effects of adaptive servo-ventilation on cardiac sympathetic nervous function in patients with heart failure evaluated using a combination of 11C-HED PET and 123I-MIBG SPECT

Tokuda, Y., Sakakibara, M., Yoshinaga, K., Yamada, S., Kamiya, K., Asakawa, N., Yoshitani, T., Noguchi, K., Manabe, O., Tamaki, N. & Tsutsui, H., Aug 15 2019, In : Journal of Nuclear Cardiology. 26, 4, p. 1079-1089 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Effects of coronary revascularization on global coronary flow reserve in stable coronary artery disease

Aikawa, T., Naya, M., Obara, M., Manabe, O., Magota, K., Koyanagawa, K., Asakawa, N., Ito, Y. M., Shiga, T., Katoh, C., Anzai, T., Tsutsui, H., Murthy, V. L. & Tamaki, N., Jan 1 2019, In : Cardiovascular research. 115, 1, p. 119-129 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Efficacy and safety of ivabradine in Japanese patients with chronic heart failure ― J-SHIFT study ―

behalf of the J-SHIFT Study Investigators, Jan 1 2019, In : Circulation Journal. 83, 10, p. 2049-2060 12 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2 Citations (Scopus)

Estimation of the baroreflex total loop gain by the power spectral analysis of continuous arterial pressure recordings

Mannoji, H., Saku, K., Nishikawa, T., Tohyama, T., Kamada, K., Abe, K., Sunagawa, G., Kishi, T., Sunagawa, K. & Tsutsui, H., Apr 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 4, p. H828-H839

Research output: Contribution to journalArticle

1 Citation (Scopus)

Evaluation of the effect of sodium–glucose co-transporter 2 inhibition with empagliflozin on morbidity and mortality of patients with chronic heart failure and a reduced ejection fraction: rationale for and design of the EMPEROR-Reduced trial

on behalf of the EMPEROR-Reduced Trial Committees and Investigators, Executive Committee, National Coordinators, Consulting Statistician, Clinical Events Committee, Scientific Excellence Committee & Data Monitoring Committee, Oct 1 2019, In : European Journal of Heart Failure. 21, 10, p. 1270-1278 9 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
Open Access
5 Citations (Scopus)
Open Access
1 Citation (Scopus)

Geographical differences and the national meeting effect in patients with out-of-hospital cardiac arrests: A JCS–ReSS study report

behalf of the Japanese Circulation Society Resuscitation Science Study (JCS-ReSS) Group, Dec 2 2019, In : International journal of environmental research and public health. 16, 24, 5130.

Research output: Contribution to journalArticle

Open Access

Heart Failure Practice in Japan: Successful at Present, but Challenging in the Future

Tsutsui, H., Mar 2019, In : Journal of Cardiac Failure. 25, 3, p. 145-146 2 p.

Research output: Contribution to journalEditorial

Heart failure with reduced ejection fraction: comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas

Dewan, P., Jhund, P. S., Shen, L., Petrie, M. C., Abraham, W. T., Atif Ali, M., Chen, C. H., Desai, A. S., Dickstein, K., Huang, J., Kiatchoosakun, S., Kim, K. S., Køber, L., Lai, W. T., Liao, Y., Mogensen, U. M., Oh, B. H., Packer, M., Rouleau, J. L., Shi, V. & 7 others, Sibulo, A. S., Solomon, S. D., Sritara, P., Swedberg, K., Tsutsui, H., Zile, M. R. & McMurray, J. J. V., May 2019, In : European Journal of Heart Failure. 21, 5, p. 577-587 11 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Hospitalization costs for patients with acute congestive heart failure in Japan

Kanaoka, K., Okayama, S., Nakai, M., Sumita, Y., Nishimura, K., Kawakami, R., Okura, H., Miyamoto, Y., Yasuda, S., Tsutsui, H., Komuro, I., Ogawa, H. & Saito, Y., Jan 1 2019, In : Circulation Journal. 83, 5, p. 1025-1031 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Hypoxia-inducible factor-1 α deletion in myeloid lineage attenuates hypoxia-induced pulmonary hypertension

Kojima, H., Tokunou, T., Takahara, Y., Sunagawa, K., Hirooka, Y., Ichiki, T. & Tsutsui, H., Apr 2019, In : Physiological Reports. 7, 7, e14025.

Research output: Contribution to journalArticle

Open Access

Inhibition of TLR9-NF-κB-mediated sterile inflammation improves pressure overload-induced right ventricular dysfunction in rats

Yoshida, K., Abe, K., Ishikawa, M., Saku, K., Shinoda-Sakamoto, M., Ishikawa, T., Watanabe, T., Oka, M., Sunagawa, K. & Tsutsui, H., Mar 1 2019, In : Cardiovascular research. 115, 3, p. 658-668 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Ivabradine for the treatment of cardiovascular diseases

Ide, T., Ohtani, K., Higo, T., Tanaka, M., Kawasaki, Y. & Tsutsui, H., Feb 2019, In : Circulation Journal. 83, 2, p. 252-260 9 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

JCS 2016 guideline on diagnosis and treatment of cardiac sarcoidosis ― digest version ―

Terasaki, F., Azuma, A., Anzai, T., Ishizaka, N., Ishida, Y., Isobe, M., Inomata, T., Ishibashi-Ueda, H., Eishi, Y., Kitakaze, M., Kusano, K., Sakata, Y., Shijubo, N., Tsuchida, A., Tsutsui, H., Nakajima, T., Nakatani, S., Horii, T., Yazaki, Y., Yamaguchi, E. & 18 others, Yamaguchi, T., Ide, T., Okamura, H., Kato, Y., Goya, M., Sakakibara, M., Soejima, K., Nagai, T., Nakamura, H., Noda, T., Hasegawa, T., Morita, H., Ohe, T., Kihara, Y., Saito, Y., Sugiyama, Y., Morimoto, S. I. & Yamashina, A., Jan 1 2019, In : Circulation Journal. 83, 11, p. 2329-2388 60 p.

Research output: Contribution to journalReview article

Open Access

JCS 2017/JHFS 2017 guideline on diagnosis and treatment of acute and chronic heart failure ― digest version ―

behalf of the Japanese Circulation Society and the Japanese Heart Failure Society Joint Working Group, Jan 1 2019, In : Circulation Journal. 83, 10, p. 2084-2184 101 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

JCS 2018 guideline on diagnosis and treatment of acute coronary syndrome

on behalf of the Japanese Circulation Society Joint Working Group, Jan 1 2019, In : Circulation Journal. 83, 5, p. 1085-1196 112 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Left atrial involvement of cardiac sarcoidosis manifesting as left atrial re-entrant tachycardia

Enzan, N., Ohtani, K., Nagaoka, K., Sakamoto, I. & Tsutsui, H., Aug 1 2019, In : European heart journal cardiovascular Imaging. 20, 8, 1 p., jez051.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Mechano-chronotropic Unloading During the Acute Phase of Myocardial Infarction Markedly Reduces Infarct Size via the Suppression of Myocardial Oxygen Consumption

Sunagawa, G., Saku, K., Arimura, T., Nishikawa, T., Mannoji, H., Kamada, K., Abe, K., Kishi, T., Tsutsui, H. & Sunagawa, K., Apr 15 2019, In : Journal of Cardiovascular Translational Research. 12, 2, p. 124-134 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J. I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., Jun 1 2019, In : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice

Fujiwara, M., Matoba, T., Koga, J-I., Okahara, A., Funamoto, D., Nakano, K., Tsutsui, H. & Egashira, K., Jun 1 2019, In : Cardiovascular research. 115, 7, p. 1244-1255 12 p.

Research output: Contribution to journalArticle

Nationwide survey of multidisciplinary care and cardiac rehabilitation for patients with heart failure in Japan ― An analysis of the AMED-CHF study ―

Kamiya, K., Yamamoto, T., Tsuchihashi-Makaya, M., Ikegame, T., Takahashi, T., Sato, Y., Kotooka, N., Saito, Y., Tsutsui, H., Miyata, H. & Isobe, M., Jan 1 2019, In : Circulation Journal. 83, 7, p. 1546-1552 7 p.

Research output: Contribution to journalArticle

Open Access

Non-Pulmonary Vein Triggers of Atrial Fibrillation Are Likely to Arise from Low-Voltage Areas in the Left Atrium

Kawai, S., Mukai, Y., Inoue, S., Yakabe, D., Nagaoka, K., Sakamoto, K., Takase, S., Chishaki, A. & Tsutsui, H., Dec 1 2019, In : Scientific reports. 9, 1, 12271.

Research output: Contribution to journalArticle

Open Access
Open Access

Number of Cardiologists per Cardiovascular Beds and In-Hospital Mortality for Acute Heart Failure: A Nationwide Study in Japan

Kanaoka, K., Okayama, S., Nakai, M., Sumita, Y., Onoue, K., Soeda, T., Nishimura, K., Kawakami, R., Okura, H., Miyamoto, Y., Yasuda, S., Tsutsui, H., Komuro, I., Ogawa, H. & Saito, Y., Sep 17 2019, In : Journal of the American Heart Association. 8, 18, p. e012282

Research output: Contribution to journalArticle

Open Access