TY - JOUR
T1 - A 6-year-old girl with an extra-axial mass in the middle cranial fossa
T2 - Com sept 2009, case 1
AU - Masui, Kenta
AU - Suzuki, Satoshi O.
AU - Kondo, Akira
AU - Iwaki, Toru
PY - 2010/1
Y1 - 2010/1
N2 - A 6-year-old Japanese girl presented with psychomotor seizures. Magnetic resonance (MR) images disclosed a mass lesion in the left middle cranial fossa with an internal irregular-shaped area, which was hyperintense on T1-weighted images and hypointense on T2-weighted images. Gross total resection of the tumor was performed through left occipital craniotomy. The tumor was white-to-grayish hard tissue, focally showing blackish pigmentation. Histological, immunohistochemical and electron-microscopical analyses revealed that white-to-grayish hard tissue corresponded to an atypical meningioma, and the blackish pigmentation of the tumor was composed of non-neoplastic, reactive hyperplasia and colonization of meningeal melanocytes in the meningioma tissue. A meningioma with reactive hyperplasia and colonization of meningeal melanocytes is unusual, but it is clinically important to differentiate this entity from other melanocytic tumors.
AB - A 6-year-old Japanese girl presented with psychomotor seizures. Magnetic resonance (MR) images disclosed a mass lesion in the left middle cranial fossa with an internal irregular-shaped area, which was hyperintense on T1-weighted images and hypointense on T2-weighted images. Gross total resection of the tumor was performed through left occipital craniotomy. The tumor was white-to-grayish hard tissue, focally showing blackish pigmentation. Histological, immunohistochemical and electron-microscopical analyses revealed that white-to-grayish hard tissue corresponded to an atypical meningioma, and the blackish pigmentation of the tumor was composed of non-neoplastic, reactive hyperplasia and colonization of meningeal melanocytes in the meningioma tissue. A meningioma with reactive hyperplasia and colonization of meningeal melanocytes is unusual, but it is clinically important to differentiate this entity from other melanocytic tumors.
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U2 - 10.1111/j.1750-3639.2009.00348.x
DO - 10.1111/j.1750-3639.2009.00348.x
M3 - Article
C2 - 20438488
AN - SCOPUS:71549119863
VL - 20
SP - 269
EP - 272
JO - Brain Pathology
JF - Brain Pathology
SN - 1015-6305
IS - 1
ER -