A 6-year-old girl with an extra-axial mass in the middle cranial fossa: Com sept 2009, case 1

Kenta Masui, Satoshi O. Suzuki, Akira Kondo, Toru Iwaki

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A 6-year-old Japanese girl presented with psychomotor seizures. Magnetic resonance (MR) images disclosed a mass lesion in the left middle cranial fossa with an internal irregular-shaped area, which was hyperintense on T1-weighted images and hypointense on T2-weighted images. Gross total resection of the tumor was performed through left occipital craniotomy. The tumor was white-to-grayish hard tissue, focally showing blackish pigmentation. Histological, immunohistochemical and electron-microscopical analyses revealed that white-to-grayish hard tissue corresponded to an atypical meningioma, and the blackish pigmentation of the tumor was composed of non-neoplastic, reactive hyperplasia and colonization of meningeal melanocytes in the meningioma tissue. A meningioma with reactive hyperplasia and colonization of meningeal melanocytes is unusual, but it is clinically important to differentiate this entity from other melanocytic tumors.

Original languageEnglish
Pages (from-to)269-272
Number of pages4
JournalBrain Pathology
Issue number1
Publication statusPublished - Jan 1 2010


All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Neuroscience(all)
  • Clinical Neurology

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