A basic study of determination matrix metalloproteinase-3 and carbohydrate in rheumatoid factor in serum for diagnosis of rheumatoid arthritis

Michiyo Urata; Nobuko Nakamura; Sachiko Kinoshita; Yuzo Kayamori; Naotaka Hamasaki

A basic study of determination matrix metalloproteinase-3 and carbohydrate in rheumatoid factor in serum for diagnosis of rheumatoid arthritis

Michiyo Urata, Nobuko Nakamura, Sachiko Kinoshita, Yuzo Kayamori, Naotaka Hamasaki

Division of Medical Technology

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Abstract

The examination of rheumatoid factor (RF), one of the diagnostic marker of rheumatoid arthritis (RA), showed negative about 25% of patients with RA. We analyzed a matrix metalloproteinase-3 (MMP-3) and a carbohydrate in rheumatoid factor (CA.RF) for diagnosis of RA: the former is used the kit "Panaclear MMP-3[Plate]" and the latter is used the kit "Picolumi CA.RF". The basic study of these reagents showed satisfactory results. In 73.3% of seronegative RA showed positive on both MMP-3 and CA.RF levels in serum, respectively. We found that these examinations might be useful for diagnosis of RA, especially during seronegative RA.

Original language	English
Pages (from-to)	745-750
Number of pages	6
Journal	Rinsho byori. The Japanese journal of clinical pathology
Volume	51
Issue number	8
Publication status	Published - Jan 1 2003

All Science Journal Classification (ASJC) codes

Medicine(all)

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A basic study of determination matrix metalloproteinase-3 and carbohydrate in rheumatoid factor in serum for diagnosis of rheumatoid arthritis. / Urata, Michiyo; Nakamura, Nobuko; Kinoshita, Sachiko et al.

In: Rinsho byori. The Japanese journal of clinical pathology, Vol. 51, No. 8, 01.01.2003, p. 745-750.

Research output: Contribution to journal › Article › peer-review

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AU - Hamasaki, Naotaka

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A basic study of determination matrix metalloproteinase-3 and carbohydrate in rheumatoid factor in serum for diagnosis of rheumatoid arthritis

Abstract

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