A bioreactor utilizing high-resolution three dimensional microchannel for on-chip platelet production

Hiroki Kumon, Shinya Sakuma, Yusuke Kasai, Sou Nakamura, Koji Eto, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Several groups have proposed microfluidic chips as small test benches to evaluate the effect of fluid force on platelet production. The conventional method is difficult to trap megakaryocytes (MKs) of various size without clogging MKs. Therefore, we proposed a 3D microchannel for applying equalized fluid force. We fabricate the 3D microchannel by using grey-scale lithography technique and DRIE including O2 plasma ashing process. As a result, we succeeded in fabrication of high resolution 3D microchannel.

Original languageEnglish
Title of host publicationMHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781538667927
DOIs
Publication statusPublished - Dec 2018
Externally publishedYes
Event29th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2018 - Nagoya, Japan
Duration: Dec 10 2018Dec 12 2018

Publication series

NameMHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science

Conference

Conference29th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2018
Country/TerritoryJapan
CityNagoya
Period12/10/1812/12/18

All Science Journal Classification (ASJC) codes

  • Human-Computer Interaction
  • Artificial Intelligence
  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Control and Optimization
  • Instrumentation

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