We herein present the case of a 45-year-old asymptomatic female who was referred to our institution for main pancreatic duct stenosis revealed by US. CT and MRI confirmed a well-defined hypervascular tumor of 4 mm in diameter in the head of the pancreas. Endoscopic ultrasound-guided fine needle aspiration and pancreatic juice cytology under ERCP showed no malignancy. Laparoscopy-assisted pancreatoduodenectomy was performed under a preoperative diagnosis of a serotonin-producing pancreatic neuroendocrine tumor (PanNET). Pathological examination of the resected specimen showed that the tumor was a serotonin-producing PanNET.
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