A case of advanced esophageal cancer with multiple lymph node metastases successfully treated with induction chemotherapy consisting of nedaplatin and 5-FU followed by chemoradiotherapy

Tomonari Sasaki, Katsumasa Nakamura, Takashi Toba, Masahiko Kimura, Saijo Ohga, Yusuke Urashima, Hiromi Terashima, Kouji Masuda

Research output: Contribution to journalArticlepeer-review

Abstract

A 61-year-old male patient had esophageal carcinoma with multiple mediastinal and right supraclavicular lymph node metastases. Chemotherapy consisting of infusion of nedaplatin and continuous infusion of 5-fluorouracil was performed. After three courses of the chemotherapy, the patient was treated with a combination of cisplatin and 5-FU and radiotherapy. However, only radiotherapy was performed after 18 Gy because of grade 3 leukocytonenia during the chemoradiotherapy. The patient achieved a partial response (nearly complete response) for 9 months after the initiation of the treatment. In conclusion, chemotherapy with NDP and 5-FU followed by chemoradiotherapy is effective and safe for patients with esophageal carcinoma with multiple lymph node metastases.

Original languageEnglish
Pages (from-to)1417-1420
Number of pages4
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume29
Issue number8
Publication statusPublished - Aug 2002

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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