A case of anterior ischemic optic neuropathy associated with dysplasminogenemia

K. Motomatsu, Y. Hata, H. Uchida, Tatsuro Ishibashi, T. Kohno, T. Okamura

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We report a case of anterior ischemic optic neuropathy associated with dysplasminogenemia. The patient, a 67-year-old male, complained of superior visual field defect and visual loss, first in his left eye, and 18 months later in his right. Despite treatment with fibrinolytic drug and corticosteroid, light sense in his left eye was lost and right visual acuity diminished to finger count. From this history, and from clinical findings, such as optic disc edema and dye leakage from optic disc in fluorescein fundus angiography, we diagnosed this case as anterior ischemic optic neuropathy. In addition to the optic disk abnormalities, arteriosclerotic changes were found in the retinal vessels. Laboratory examination revealed a low level of plasminogen activity in the plasma, but a normal concentration of plasminogen antigen. These results suggest that circulatory disturbance can occur in patients with dysplasminogenemia when risk factors such as arteriosclerosis are associated.

Original languageEnglish
Pages (from-to)1046-1049
Number of pages4
JournalFolia Ophthalmologica Japonica
Volume45
Issue number10
Publication statusPublished - Dec 27 1994

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Ischemic Optic Neuropathy
Plasminogen
Optic Disk
Retinal Vessels
Papilledema
Fibrinolytic Agents
Arteriosclerosis
Fluorescein Angiography
Visual Fields
Fingers
Visual Acuity
Adrenal Cortex Hormones
Coloring Agents
History
Light
Antigens
Type I Plasminogen Deficiency
Therapeutics

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Motomatsu, K., Hata, Y., Uchida, H., Ishibashi, T., Kohno, T., & Okamura, T. (1994). A case of anterior ischemic optic neuropathy associated with dysplasminogenemia. Folia Ophthalmologica Japonica, 45(10), 1046-1049.

A case of anterior ischemic optic neuropathy associated with dysplasminogenemia. / Motomatsu, K.; Hata, Y.; Uchida, H.; Ishibashi, Tatsuro; Kohno, T.; Okamura, T.

In: Folia Ophthalmologica Japonica, Vol. 45, No. 10, 27.12.1994, p. 1046-1049.

Research output: Contribution to journalArticle

Motomatsu, K, Hata, Y, Uchida, H, Ishibashi, T, Kohno, T & Okamura, T 1994, 'A case of anterior ischemic optic neuropathy associated with dysplasminogenemia', Folia Ophthalmologica Japonica, vol. 45, no. 10, pp. 1046-1049.
Motomatsu K, Hata Y, Uchida H, Ishibashi T, Kohno T, Okamura T. A case of anterior ischemic optic neuropathy associated with dysplasminogenemia. Folia Ophthalmologica Japonica. 1994 Dec 27;45(10):1046-1049.
Motomatsu, K. ; Hata, Y. ; Uchida, H. ; Ishibashi, Tatsuro ; Kohno, T. ; Okamura, T. / A case of anterior ischemic optic neuropathy associated with dysplasminogenemia. In: Folia Ophthalmologica Japonica. 1994 ; Vol. 45, No. 10. pp. 1046-1049.
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