A case of anti-SS-A and anti-SS-B antibody-positive lipoatropy

Yumiko Arao, Futoshi Kohda, Kyoko Nakamura, Manabu Hamada, Yoichi Moroi, Kazunori Urabe, Masutaka Furue

Research output: Contribution to journalArticle

Abstract

A 66-year-old woman noticed cutaneous concavities of 2-3 cm in diameter on her upper arms in 1999. Similar lesions gradually developed on her forearms, chest, and back. Anti-SS-A and anti-SS-B antibodies were positive. The histopathological examination revealed a degeneration of lipocytes with infiltration of lymphocytes and macrophages. An immunofluorescence microscopic study demonstrated no deposition of immunoglobulin and complement in the basement membrane zone. These findings led to the diagnosis of the inflammatory type of localized lipoatrophy. This clinical entity is equivalent to lipoatrophic connective tissue panniculitis. The pathogenesis is unknown; however, an autoimmune mechanism may be involved.

Original languageEnglish
Pages (from-to)113-115
Number of pages3
JournalNishinihon Journal of Dermatology
Volume67
Issue number2
DOIs
Publication statusPublished - May 18 2005

Fingerprint

Panniculitis
Adipocytes
Basement Membrane
Forearm
Connective Tissue
Fluorescent Antibody Technique
Immunoglobulins
Arm
Thorax
Macrophages
Lymphocytes
Skin
SS-B antibodies

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

A case of anti-SS-A and anti-SS-B antibody-positive lipoatropy. / Arao, Yumiko; Kohda, Futoshi; Nakamura, Kyoko; Hamada, Manabu; Moroi, Yoichi; Urabe, Kazunori; Furue, Masutaka.

In: Nishinihon Journal of Dermatology, Vol. 67, No. 2, 18.05.2005, p. 113-115.

Research output: Contribution to journalArticle

Arao, Y, Kohda, F, Nakamura, K, Hamada, M, Moroi, Y, Urabe, K & Furue, M 2005, 'A case of anti-SS-A and anti-SS-B antibody-positive lipoatropy', Nishinihon Journal of Dermatology, vol. 67, no. 2, pp. 113-115. https://doi.org/10.2336/nishinihonhifu.67.113
Arao Y, Kohda F, Nakamura K, Hamada M, Moroi Y, Urabe K et al. A case of anti-SS-A and anti-SS-B antibody-positive lipoatropy. Nishinihon Journal of Dermatology. 2005 May 18;67(2):113-115. https://doi.org/10.2336/nishinihonhifu.67.113
Arao, Yumiko ; Kohda, Futoshi ; Nakamura, Kyoko ; Hamada, Manabu ; Moroi, Yoichi ; Urabe, Kazunori ; Furue, Masutaka. / A case of anti-SS-A and anti-SS-B antibody-positive lipoatropy. In: Nishinihon Journal of Dermatology. 2005 ; Vol. 67, No. 2. pp. 113-115.
@article{c93832f4259f458094f3c2542a3d6b6a,
title = "A case of anti-SS-A and anti-SS-B antibody-positive lipoatropy",
abstract = "A 66-year-old woman noticed cutaneous concavities of 2-3 cm in diameter on her upper arms in 1999. Similar lesions gradually developed on her forearms, chest, and back. Anti-SS-A and anti-SS-B antibodies were positive. The histopathological examination revealed a degeneration of lipocytes with infiltration of lymphocytes and macrophages. An immunofluorescence microscopic study demonstrated no deposition of immunoglobulin and complement in the basement membrane zone. These findings led to the diagnosis of the inflammatory type of localized lipoatrophy. This clinical entity is equivalent to lipoatrophic connective tissue panniculitis. The pathogenesis is unknown; however, an autoimmune mechanism may be involved.",
author = "Yumiko Arao and Futoshi Kohda and Kyoko Nakamura and Manabu Hamada and Yoichi Moroi and Kazunori Urabe and Masutaka Furue",
year = "2005",
month = "5",
day = "18",
doi = "10.2336/nishinihonhifu.67.113",
language = "English",
volume = "67",
pages = "113--115",
journal = "Nishinihon Journal of Dermatology",
issn = "0386-9784",
publisher = "Kyushu University, Faculty of Science",
number = "2",

}

TY - JOUR

T1 - A case of anti-SS-A and anti-SS-B antibody-positive lipoatropy

AU - Arao, Yumiko

AU - Kohda, Futoshi

AU - Nakamura, Kyoko

AU - Hamada, Manabu

AU - Moroi, Yoichi

AU - Urabe, Kazunori

AU - Furue, Masutaka

PY - 2005/5/18

Y1 - 2005/5/18

N2 - A 66-year-old woman noticed cutaneous concavities of 2-3 cm in diameter on her upper arms in 1999. Similar lesions gradually developed on her forearms, chest, and back. Anti-SS-A and anti-SS-B antibodies were positive. The histopathological examination revealed a degeneration of lipocytes with infiltration of lymphocytes and macrophages. An immunofluorescence microscopic study demonstrated no deposition of immunoglobulin and complement in the basement membrane zone. These findings led to the diagnosis of the inflammatory type of localized lipoatrophy. This clinical entity is equivalent to lipoatrophic connective tissue panniculitis. The pathogenesis is unknown; however, an autoimmune mechanism may be involved.

AB - A 66-year-old woman noticed cutaneous concavities of 2-3 cm in diameter on her upper arms in 1999. Similar lesions gradually developed on her forearms, chest, and back. Anti-SS-A and anti-SS-B antibodies were positive. The histopathological examination revealed a degeneration of lipocytes with infiltration of lymphocytes and macrophages. An immunofluorescence microscopic study demonstrated no deposition of immunoglobulin and complement in the basement membrane zone. These findings led to the diagnosis of the inflammatory type of localized lipoatrophy. This clinical entity is equivalent to lipoatrophic connective tissue panniculitis. The pathogenesis is unknown; however, an autoimmune mechanism may be involved.

UR - http://www.scopus.com/inward/record.url?scp=18244373688&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=18244373688&partnerID=8YFLogxK

U2 - 10.2336/nishinihonhifu.67.113

DO - 10.2336/nishinihonhifu.67.113

M3 - Article

AN - SCOPUS:18244373688

VL - 67

SP - 113

EP - 115

JO - Nishinihon Journal of Dermatology

JF - Nishinihon Journal of Dermatology

SN - 0386-9784

IS - 2

ER -