We report the case of a 63-year-old Japanese woman who was hospitalized for the diagnosis and treatment of a fever of unknown origin. Based on several laboratory findings including a bone marrow and peripheral blood check, she was diagnosed to have chronic phase chronic myelomonocytic leukemia (CMMoL). Thereafter the patient simultaneously developed palpable purpuras on both thighs with blastic transformation of CMMoL. Histopathological examination showed a leukemic infiltration in the reticular dermis with an extravasation of red blood cells.
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